<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vishu Manchanda</style></author><author><style face="normal" font="default" size="100%">Bhagyalakshmi K</style></author><author><style face="normal" font="default" size="100%">Nayanatara Arun Kumar</style></author><author><style face="normal" font="default" size="100%">Anupama N</style></author><author><style face="normal" font="default" size="100%">Rekha D Kini</style></author><author><style face="normal" font="default" size="100%">Sneha Shetty</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Intermittent Fasting as a Non-Invasive Strategy to Mitigate Diabetes-Induced Complications in Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Intermittent fasting; Type 2 diabetes mellitus; Alloxan; Wistar rats; Physiological changes; Biochemical parameters; Histological changes</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">632-637</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; The global burden of diabetes mellitus is steadily increasing. Abnormal eating patterns and excess energy intake contribute to obesity and type 2 diabetes mellitus (T2DM). Although dietary modifications such as intermittent fasting have gained attention, evidence supporting their beneficial role in T2DM is limited. &lt;strong&gt;Objective: &lt;/strong&gt;To evaluate the beneficial effects of intermittent fasting on physiological, biochemical, and histological changes in a rat model of type 2 diabetes mellitus. &lt;strong&gt;Methods:&lt;/strong&gt; Healthy adult Wistar albino rats (150–200 g) were used. Diabetes was induced by administering alloxan (150 mg/kg). Animals were divided into four groups: Normal Control (Group I), Experimental Control (Group II), and Intermittent Fasting groups (Group III &amp;amp; Group IV). Physiological, biochemical, and histological parameters were assessed to determine the impact of intermittent fasting. Results: Intermittent fasting demonstrated a protective effect by reducing diabetes-induced physiological, biochemical, and histological alterations. Rats in the intermittent fasting groups showed improved outcomes compared to the experimental control group. &lt;strong&gt;Conclusion:&lt;/strong&gt; Intermittent fasting may serve as a potential non-invasive strategy to reduce diabetesrelated complications. Further studies focusing on molecular mechanisms are warranted to provide deeper insights into its protective role.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">632</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Vishu Manchanda&lt;sup&gt;1&lt;/sup&gt;, Bhagyalakshmi K&lt;sup&gt;1*&lt;/sup&gt;, Nayanatara Arun Kumar&lt;sup&gt;1&lt;/sup&gt;, Anupama N&lt;sup&gt;1&lt;/sup&gt;, Rekha D Kini&lt;sup&gt;1&lt;/sup&gt;, Sneha Shetty&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Physiology, Kasturba Medical College Mangalore, Manipal Academy Higher Education, Manipal, India&lt;/p&gt;
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