<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Erich Christian Wayangkau</style></author><author><style face="normal" font="default" size="100%">Budiyono Budiyono</style></author><author><style face="normal" font="default" size="100%">Martini Martini</style></author><author><style face="normal" font="default" size="100%">Mursid Raharjo</style></author><author><style face="normal" font="default" size="100%">Bagoes Widjanarko</style></author><author><style face="normal" font="default" size="100%">Daru Lestantyo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effectiveness of the UFESA Model: A Culturally Grounded Intervention to Improve Adherence to Lymphatic Filariasis Mass Drug Administration in Papua, Indonesia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">adherence</style></keyword><keyword><style  face="normal" font="default" size="100%">Filariasis</style></keyword><keyword><style  face="normal" font="default" size="100%">Local culture</style></keyword><keyword><style  face="normal" font="default" size="100%">mass drug administration</style></keyword><keyword><style  face="normal" font="default" size="100%">psychometric testing</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2026</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2026</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">18</style></volume><pages><style face="normal" font="default" size="100%">55-62</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Lymphatic filariasis remains a public health challenge in Papua because of low adherence to mass drug administration (MDA). Objective: This study evaluated the effectiveness of the UFESA model—a culturally tailored intervention integrating health education, family support, and traditional leader engagement—in improving adherence to preventive filariasis medication in Sarmi District. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;A quasiexperimental pretest–posttest control group design was implemented across two health centers (intervention: Bagaiserwar; control: Sarmi Kota), with 160 participants recruited via multistage random sampling. The primary outcome was adherence across three MDA cycles; secondary outcomes included knowledge, attitudes, and support measures. The data were analyzed via chi-square, Mann– Whitney U, and Wilcoxon tests. &lt;strong&gt;Results: &lt;/strong&gt;Adherence increased from 38.8% to 87.5% in the intervention group, whereas it increased from 26.2% to 52.5% in the control group (&lt;em&gt;p &lt;/em&gt;&amp;lt; 0.001). All the adherence dimensions were significantly greater in the intervention group. Knowledge increased from 3.00 to 10.00 (intervention) versus 2.00 to 4.00 (control), with similar improvements in attitudes and support (&lt;em&gt;p&lt;/em&gt; &amp;lt; 0.001). The instruments showed strong reliability (α &amp;gt; 0.80) and validity. The effect sizes were medium to large (Cohen's d=0.68–0.78; Cramer's V=0.38–0.45).&lt;strong&gt; Conclusion: &lt;/strong&gt;The findings provide evidence of the effectiveness of the UFESA model in enhancing medication adherence and addressing psychosocial determinants, highlighting the value of culturally grounded, psychometrically rigorous interventions in public health.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">55</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Erich Christian Wayangkau&lt;sup&gt;1,2*&lt;/sup&gt;, Budiyono Budiyono&lt;sup&gt;3&lt;/sup&gt;, Martini Martini&lt;sup&gt;4&lt;/sup&gt;, Mursid Raharjo&lt;sup&gt;3&lt;/sup&gt;, Bagoes Widjanarko&lt;sup&gt;5&lt;/sup&gt;, Daru Lestantyo&lt;sup&gt;6&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Doctoral Program, Faculty of Public Health, Diponegoro University, Semarang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Public Health, Cenderawasih University, Jayapura, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Environmental Health, Faculty of Public Health, Diponegoro University, Semarang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Epidemiology, Faculty of Public Health, Diponegoro University, Semarang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Health Promotion and Behavioral Science, Faculty of Public Health, Diponegoro University, Semarang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Occupational Health and Safety, Faculty of Public Health, Diponegoro University, Semarang, INDONESIA.&lt;/p&gt;
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