<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sushma Devi</style></author><author><style face="normal" font="default" size="100%">Randhir Singh</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant and Anti-hypercholesterolemic potential of Vitis vinifera leaves</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Cholesterol Diet</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypercholesterolemia</style></keyword><keyword><style  face="normal" font="default" size="100%">Total Phenolic Content Etc.</style></keyword><keyword><style  face="normal" font="default" size="100%">Vitis vinifera</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/179</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">807-814</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Grapes (&lt;em&gt;Vitis vinifera&lt;/em&gt;) are universally appreciated fruit for their delicacy, nutrition and accepted as functional food. The objective of the present study is to evaluate antioxidant and anti-hypercholesterolemic potential of &lt;em&gt;Vitis vinifera&lt;/em&gt; leaves extract. &lt;strong&gt;Methods:&lt;/strong&gt; Qualitative and quantitative phytochemical screening of methanolic (VVME) and aqueous (VVAE) extract was carried out to identify the phytoconstituents. Antioxidant potential was evaluated by employing &lt;em&gt;in-vitro&lt;/em&gt; and &lt;em&gt;in vivo&lt;/em&gt; assays. The anti-hypercholesterolemic activity was evaluated by inducing hypercholesterolemia with high cholesterol diet for 21 days in experimental animals. &lt;strong&gt;Results:&lt;/strong&gt; In VVME, total tannins, total flavonoids and total phenolic contents were found to be present in major amount. Both extract has significant &lt;em&gt;in-vitro&lt;/em&gt; and &lt;em&gt;in-vivo&lt;/em&gt; antioxidant efficacy. Different doses i.e. 100, 200 and 400 mg/kg of VVME and VVAE significantly attenuated the lipid levels. Moreover, VVME was found to be more effective as compared to VVAE and also, effectiveness was confirmed with histological results. &lt;strong&gt;Conclusion:&lt;/strong&gt; It can be concluded that antioxidant and anti-hypercholesterolemic efficacy of &lt;em&gt;Vitis vinifera&lt;/em&gt; might be due to presence of antioxidant property and active phytoconstituents.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">807</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sushma Devi,&lt;sup&gt;&amp;nbsp;&lt;/sup&gt;Randhir Singh&lt;sup&gt;*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmaceutical Sciences, Maharishi Markandeshwar University, Mullana, Ambala, Haryana, INDIA.&lt;/p&gt;</style></auth-address></record></records></xml>