<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">shreelakshmidevi singaravelu</style></author><author><style face="normal" font="default" size="100%">Jaikumar Sankarapillai</style></author><author><style face="normal" font="default" size="100%">Abilash Sasidaran Chandrakumari</style></author><author><style face="normal" font="default" size="100%">Pammy Sinha</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of Trigonella foenum gracecum (fenugreek) Seed Extract in Experimentally Induced Gastric Ulcer in Wistar Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Fenugreek</style></keyword><keyword><style  face="normal" font="default" size="100%">Gastro-protection</style></keyword><keyword><style  face="normal" font="default" size="100%">Indomethacin</style></keyword><keyword><style  face="normal" font="default" size="100%">seed-extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Ulcer inhibition</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">1169-1173</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; &lt;em&gt;Trigonella foenum graceum&lt;/em&gt; (Fenugreek) seeds are commonly used in India as traditional medicine for Diabetes, Dysmenorrhea, lactation and arthritis. The gastro-protective role of Fenugreek seeds are yet to be explored. &lt;strong&gt;Objectives:&lt;/strong&gt; To evaluate the effect of Fenugreek seed extract in Indomethacin induced gastric ulcer models. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Albino wistar rats were divided into five groups with eight animals in each. Gastric ulcer was induced using Indomethacin 20 mg/Kg. Fenugreek at dose of 200mg/Kg and 400mg/Kg was administered to group III, IV and group V received Rantidine 30mg/Kg. Ulcer index, volume of gastric juice and acidity was estimated. To study the anti-oxidant property the level of catalase, SOD, GST and T. Bars were done. &lt;strong&gt;Results:&lt;/strong&gt; Fenugreek treated group III showed a significant decrease in ulcer index, volume of gastric juice and acidity when compared to control positive group II. Oxidative enzyme study indicated a significant increase in Catalase, SOD and GSH value in treated group when compared with control positive group II and significant decrease in T. Bars value in treated group. &lt;strong&gt;Conclusion:&lt;/strong&gt; Fenugreek seed extract has both gastro-protective and Anti-oxidant property.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1169</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Shreelakshmidevi Singaravelu&lt;sup&gt;1,5&lt;/sup&gt;*, Jaikumar Sankarapillai&lt;sup&gt;2&lt;/sup&gt;, Abilash Sasidaran Chandrakumari&lt;sup&gt;3,5&lt;/sup&gt;, Pammy Sinha&lt;sup&gt;4 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, Shri Sathya Sai Medical College and Research Institute, Sri Balaji Vidyapeeth, Chennai, Tamil Nadu, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacology, Sri Lakshmi Narayana Institute of Medical Science Medical College and Hospital, Puducherry, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pathology, Shri Sathya Sai Medical College and Research Institute, Sri Balaji Vidyapeeth (DU), Chennai, Tamil Nadu, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Pathology, Sri Lakshmi Narayana Institute of Medical Science Medical College and Hospital, BIHER, Puducherry, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Research scholar, Bharath institute of higher education and research, Chennai, Tamil Nadu, INDIA.&lt;/p&gt;</style></auth-address></record></records></xml>