<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Arini Wulansari</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Arikadia Noviani</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Arginase Inhibitory and Antioxidant Activities of Caesalpinia coriaria (Jacq.) Willd. Bark Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Arginase inhibitory activity</style></keyword><keyword><style  face="normal" font="default" size="100%">C. coriaria</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemicalscreening</style></keyword><keyword><style  face="normal" font="default" size="100%">total flavonoid content</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">1174-1179</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The aim of this study was to investigate the arginase inhibitory and the antioxidant activities of the bark extract of &lt;em&gt;Caesalpinia coriaria&lt;/em&gt; (Jacq.) Willd. (Dewi tree). &lt;strong&gt;Methods:&lt;/strong&gt; The bark of Dewi tree was extracted successively under reflux condition with n-hexane, ethyl acetate, and methanol. Each extract was tested for its activity in inhibiting arginase activity by measuring the quantity of urea produced in the reaction mixture using a microplate reader. The active extracts were determined for their total flavonoid content followed by antioxidant activity by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method using ultraviolet-visible spectrophotometry with ascorbic acid as standard. Phytochemical screening was conducted to determine the presence of alkaloids, saponins, flavonoids, tannins, and steroids. &lt;strong&gt;Results:&lt;/strong&gt; Arginase inhibitory activity test showed that the ethyl acetate and methanol extracts have average inhibition values of 14.43 and 33.59%, respectively, at concentration of 100 &amp;mu;g/mL. The total flavonoid content of the methanol and ethyl acetate extract were 7.75 and 6.30 mgQE/g sample, respectively. The methanol and ethyl acetate extracts showed antioxidant activity with an IC&lt;sub&gt;50&lt;/sub&gt; values of 4.720 and 3.647 &amp;mu;g/mL, respectively. The ethyl acetate extract contained flavonoid, tannin, saponin, and steroid, while the methanol extract contained flavonoid, tannin, and saponin. &lt;strong&gt;Conclusion:&lt;/strong&gt; In conclusion, &lt;em&gt;C. coriaria&lt;/em&gt; bark extracts possessed low arginase inhibitory activity. The methanol and ethyl acetate extracts have good antioxidant activity.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1174</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Arini Wulansari, Berna Elya*, Arikadia Noviani &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacognosy- Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok 16424 West Java, INDONESIA.&lt;/p&gt;</style></auth-address></record></records></xml>