<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rajesh Maheshwari</style></author><author><style face="normal" font="default" size="100%">Bhagyashree Pandya</style></author><author><style face="normal" font="default" size="100%">Ramachandran Balaraman</style></author><author><style face="normal" font="default" size="100%">Avinash Kumar Seth</style></author><author><style face="normal" font="default" size="100%">Yogesh Chand Yadav</style></author><author><style face="normal" font="default" size="100%">Vasa Siva Sankar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective effect of Livplus-A polyherbal formulation</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">CCl4</style></keyword><keyword><style  face="normal" font="default" size="100%">GGT</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatic enzymes.</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Livplus</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">01/2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">311-316</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The aim of the present study was to investigate the hepatoprotective effect of Livplus (a polyherbal formulation) against CCl&lt;sub&gt;4&lt;/sub&gt;-induced hepatotoxicity in rats. &lt;strong&gt;Methods:&lt;/strong&gt; Hepatotoxicity was induced in rats by i.p. injection of CCl&lt;sub&gt;4&lt;/sub&gt; once three days for 14 days. Livplus or Silymarin was administered along with CCl&lt;sub&gt;4&lt;/sub&gt; and the biochemical parameters like aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkalinephosphatase (ALP), total bilirubin (TB), direct bilirubin, total protein (TP), gamma-glutamyl transferase (GGT), total cholesterol (TC) and triglycerides (TG) were estimated. Furthermore, biomarkers of oxidative stress such as MDA levels, Glutathione contents, SOD and catalase activity in liver tissue were estimated. &lt;strong&gt;Results:&lt;/strong&gt; Treatment with Livplus significantly reduced the elevated levels of ALT, AST, ALP, bilirubin (direct and total), GGT, TC, TG and increased levels of TP compared to CCl&lt;sub&gt;4&lt;/sub&gt; control rats. The treatment with Livplus also showed a significant increase in glutathione contents, SOD and catalase activity and a decrease in MDA levels compared to CCl&lt;sub&gt;4&lt;/sub&gt; control rats. &lt;strong&gt;Conclusion:&lt;/strong&gt; The finding of present study indicates that Livplus showed a potential hepatoprotective activity. These results support the traditional use of Livplus in the treatment of liver disorders.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">311</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Rajesh Maheshwari&lt;sup&gt;*&lt;/sup&gt;, Bhagyashree Pandya, Ramachandran Balaraman, Avinash Kumar Seth, Yogesh Chand Yadav and Vasa Siva Sankar&lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacy, Sumandeep Vidyapeeth, Piparia, Vadodara, Gujarat, India.&lt;/p&gt;
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