<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ridzwan Norhaslinda</style></author><author><style face="normal" font="default" size="100%">Jumli Mimie Noratiqah</style></author><author><style face="normal" font="default" size="100%">Baig Atif Amin</style></author><author><style face="normal" font="default" size="100%">Rohin Mohd Adzim Khalili</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantitative and Optimization of Anthocyanin Extracted from Pomegranate (Punica Granatum) Extract by High-Performance Liquid Chromatography (HPLC)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">5-diglucoside</style></keyword><keyword><style  face="normal" font="default" size="100%">Cyanidin 3</style></keyword><keyword><style  face="normal" font="default" size="100%">Cyanidin 3-glucoside</style></keyword><keyword><style  face="normal" font="default" size="100%">Pelargonidin 3</style></keyword><keyword><style  face="normal" font="default" size="100%">Pelargonidin 3-glucoside</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/645</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">650-653</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; &lt;em&gt;P. granatum&lt;/em&gt; is one of the oldest edible fruits of tropical and subtropical regions. This fruit had high antioxidant contained by hydrolysable tannins and anthocyanin compounds that give many health benefit properties. This study aims to quantify and optimized anthocyanin from &lt;em&gt;P. granatum&lt;/em&gt; extract. &lt;strong&gt;Methods:&lt;/strong&gt; A total of 50g of the flesh was soaked into two different polar solvents; water and 50% ethanol within a ratio of 1:10; w/v for 24-hr. Then, three different methods of extraction were done and test each with HPLC analytical, respectively. &lt;strong&gt;Results:&lt;/strong&gt; The validated method proved to be linear in the range of 5 &amp;ndash; 30 ug/mL and with LOD and LOQ determined respectively for Cy3, Cy3, 5, Pg3, and Pg3, 5. The method also shows recovery (%) close to 100 when accuracy was accessed. For samples, blender water extract had a higher composition of Cy3, Cy3, 5 and Pg3, 5 (22.77 &amp;plusmn; 8.82 mg/100 g e.p; 25.36 &amp;plusmn; 9.95 mg/100 g e.p; 11.16 &amp;plusmn; 5.85 mg/100 g e.p) content as compared to other. &lt;strong&gt;Conclusion:&lt;/strong&gt; As a conclusion, the present methodology proved to be capable of detecting and quantifying Cy3, Cy3, 5, Pg3, Pg3, 5 in a single run. Also, comparatively the composition of each AC detected in blender water extract is significantly higher in value than the other methods. It should regard as a valuable source of antioxidant with the potential used for health benefits properties worldwide.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">650</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ridzwan Norhaslinda&lt;sup&gt;1&lt;/sup&gt;, Jumli Mimie Noratiqah&lt;sup&gt;1&lt;/sup&gt;, Baig Atif Amin&lt;sup&gt;2&lt;/sup&gt;, Rohin Mohd Adzim Khalili&lt;sup&gt;1,3,4&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Nutrition and Dietetic, Faculty of Health Sciences, University Sultan Zainal Abidin (UniSZA), Gong Badak Campus, Kuala Nerus, Terengganu, MALAYSIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Medicine, University Sultan Zainal Abidin, Medical Campus, Jalan Sultan Mahmud, Kuala Terengganu, Terengganu Darul Iman, MALAYSIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Centre for Continuing Education (CCE), Universiti Sultan Zainal Abidin (UniSZA), Gong Badak Campus, 21300 Kuala Nerus, Terengganu, MALAYSIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Institute for Community (Health) Development, Universiti Sultan Zainal Abidin (UniSZA), Gong Badak Campus, 21300 Kuala Nerus, Terengganu, MALAYSIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Jumli Mimie Noratiqah</style></author><author><style face="normal" font="default" size="100%">Ridzwan Norhaslinda</style></author><author><style face="normal" font="default" size="100%">Baig Atif Amin</style></author><author><style face="normal" font="default" size="100%">Rohin Mohd Adzim Khalili</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantitative and Optimization of Phenolic Acid Extracted from Pomegranate by High Performance Liquid Chromatography (HPLC)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Caffeic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Ellagic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Ferulic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Gallic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Pomegranate extract</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">969-972</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; Pomegranate is scientifically known as &lt;em&gt;Punica granatum&lt;/em&gt; L. which is a nutrient dense fruit rich in phytochemical compounds. Phenolic content is the main compound attribute for the most of the functional properties in pomegranate. The aim of this study is to quantify and optimize the composition of phenolic acids extracted from pomegranate extract by using High-performance Liquid Chromatography (HPLC). &lt;strong&gt;Method:&lt;/strong&gt; The pomegranate extracted with three different methods by using two different solvents which is 50% ethanol and water. The methods were blended (aril+ seed), Soaking (aril+ seed) and soaking + squeezed manually. HPLC-PDA was used as equipment to quantify and optimize the phenolic acids extracted from pomegranate. Result: Validation method of HPLC was analysed according to the percentage of recovery, LOD, LOQ and coefficient correlation. Result showed that GA was detected in all sample from different method of extraction applied while CA compound not detected in any of extraction method applied. FA compound was only detected in blended method by 50% ethanol and water as solvent while EA compound was detected only in water extraction of all three methods applied. &lt;strong&gt;Conclusion:&lt;/strong&gt; As a conclusion, according to the standard calibration data curve showed that this method proved to detect and quantify the targeted compounds. By comparing the data obtained from this study, it showed that water blended extract method is significantly higher content of targeted compound except for the CA compound. To the best of our knowledge, this sample can be a valuable source of antioxidant for better used in health benefits.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">969</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Jumli Mimie Noratiqah&lt;sup&gt;1&lt;/sup&gt;, Ridzwan Norhaslinda&lt;sup&gt;1&lt;/sup&gt;, Baig Atif Amin&lt;sup&gt;2&lt;/sup&gt;, Rohin Mohd Adzim Khalili&lt;sup&gt;1,3,4* &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Nutrition and Dietetic, Faculty of Health Sciences, Universiti Sultan Zainal Abidin (UniSZA), Gong Badak Campus, 21300 Kuala Nerus, Terengganu, MALAYSIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Medicine, Universiti Sultan Zainal Abidin (UniSZA), Medical Campus, Jalan Sultan Mahmud, 20400 Kuala Terengganu, Terengganu, MALAYSIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Centre for Continuing Education (CCE), Universiti Sultan Zainal Abidin (UniSZA), Gong Badak Campus, 21300 Kuala Nerus, Terengganu, MALAYSIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Institute for Community (Health) Development, Universiti Sultan Zainal Abidin (UniSZA), Gong Badak Campus, 21300 Kuala Nerus, Terengganu, MALAYSIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rohin Mohd Adzim Khalili</style></author><author><style face="normal" font="default" size="100%">Jumli Mimie Noratiqah</style></author><author><style face="normal" font="default" size="100%">Ridzwan Norhaslinda</style></author><author><style face="normal" font="default" size="100%">Abd Hadi Norhayati</style></author><author><style face="normal" font="default" size="100%">Baig Atif Amin</style></author><author><style face="normal" font="default" size="100%">Arshad Roslan</style></author><author><style face="normal" font="default" size="100%">A. Latif Ahmad Zubaidi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Cytotoxicity Effect and Morphological Study of Different Duku(Lansium domesticum corr.) Extract towards Human Colorectal Adenocarcinoma Cells Line (HT-29)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-proliferative effect</style></keyword><keyword><style  face="normal" font="default" size="100%">colorectal cancer</style></keyword><keyword><style  face="normal" font="default" size="100%">IC50 value.</style></keyword><keyword><style  face="normal" font="default" size="100%">MTT Assay</style></keyword><keyword><style  face="normal" font="default" size="100%">polarity extracts</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/172</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">757-761</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Context:&lt;/strong&gt; &lt;em&gt;Lansium domesticum&lt;/em&gt; corr. is a member of the family Meliaceae, and known locally as duku and has been used traditionally in the prevention and treatment of various illness. &lt;strong&gt;Aim:&lt;/strong&gt; To study the cytotoxic effect and morphological changes of human colorectal adenocarcinoma cells (HT-29) treated with different duku &lt;em&gt;(Lansium domesticum&lt;/em&gt; corr.) extracts. &lt;strong&gt;Methods:&lt;/strong&gt; The &lt;em&gt;L.domesticum&lt;/em&gt; corr. fruit extracts were processed involving three different solvents; methanol, ethanol and ethyl acetate. HT-29 cell lines were treated with different concentrations of &lt;em&gt;L. domesticum&lt;/em&gt; corr. (0-100 &amp;mu;g/ml) extracts for a total of 24, 48 and 72 hours. Cytotoxicity of cells line was determined by using MTT assay as per IC&lt;sub&gt;50&lt;/sub&gt; values. &lt;strong&gt;Results:&lt;/strong&gt; Methanol extract of &lt;em&gt;L. domesticum&lt;/em&gt; corr. showed IC&lt;sub&gt;50&lt;/sub&gt; value at 6.79 &amp;plusmn; 0.00 &amp;mu;g/ml and 50.0 &amp;plusmn; 0.00 &amp;mu;g/ml respective, while ethyl acetate extract of L. domesticum corr. reached IC&lt;sub&gt;50&lt;/sub&gt; value at 86.00 &amp;plusmn; 0.08 &amp;mu;g/ml, and 96.0 &amp;plusmn; 0.12 &amp;mu;g/ml. There was no IC&lt;sub&gt;50&lt;/sub&gt; value of ethanol extract from &lt;em&gt;L.domesticum&lt;/em&gt; corr. Only methanol extract showed toxicity towards HT-29 cells line. &lt;strong&gt;Conclusion:&lt;/strong&gt; To the best of our knowledge, this is the first repeat the exploring the effect of duku (&lt;em&gt;L. domesticum&lt;/em&gt; corr.) extract on HT-29 cells line.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">757</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Rohin Mohd Adzim Khalili, Jumli Mimie Noratiqah, Ridzwan Norhaslinda, Abd Hadi Norhayati, Baig Atif Amin, Arshad Roslan, A. Latif Ahmad Zubaidi&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Faculty of Health Sciences, Universiti Sultan Zainal Abidin, Gong Badak Campus, Hafsah Block, 21300 Kuala Nerus, Terengganu Darul Iman, MALAYSIA.&lt;/p&gt;</style></auth-address></record></records></xml>