<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gaurav Sharma</style></author><author><style face="normal" font="default" size="100%">Sunil Kumar</style></author><author><style face="normal" font="default" size="100%">Megha Sharma</style></author><author><style face="normal" font="default" size="100%">Navneet Upadhyay</style></author><author><style face="normal" font="default" size="100%">Sunil Kumar</style></author><author><style face="normal" font="default" size="100%">Zabeer Ahmed</style></author><author><style face="normal" font="default" size="100%">Neeraj Mahindroo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-Diabetic, Anti-Oxidant and Anti-Adipogenic Potential of Quercetin Rich Ethyl Acetate Fraction of Prunus persica</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-adipogenic</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-diabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-oxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Prunus persica</style></keyword><keyword><style  face="normal" font="default" size="100%">Quercetin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/509</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">463-469</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Diabetes mellitus is enfeebling threatening diseases with continuously increasing rates of incidence and mortality and it may rise tremendously by 2025. &lt;strong&gt;Objective:&lt;/strong&gt; Quercetin rich ethyl acetate fraction (PP-EtOA) of leaves of &lt;em&gt;Prunus persica&lt;/em&gt; was evaluated for antidiabetic, anti-oxidant and anti-adipogenic activities. Material and Methods: Streptozotocin (STZ)-induced diabetic rat model, oral glucose tolerance test (OGTT) and normalglycemic rat models were investigated at the doseof 100 and 200 mg/kg,&lt;em&gt;p.o&lt;/em&gt;. of PP-EtOA. &lt;strong&gt;Results:&lt;/strong&gt; At 200 mg/kg, significant anti-hyperglycaemic activity(&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05) was observed in all the rat models. In STZ induced diabetic rat model, improvement in body weight and lipid profile was also observed.DPPH (2,2&amp;rsquo;-diphenyl-1-picrylhydrazyl) free radical scavenging method showed dose dependent scavenging. Preadipocyte differentiation assay (3T3-L1) showed significant inhibition of differentiation. HPLC fingerprinting analysis of fraction was also performed. &lt;strong&gt;Conclusion:&lt;/strong&gt; PP-EtOA possesses potent free radical scavenging property. Its antihyperglycemic and antiadipogenic activities may be due to quercetin (flavonoid) and may prove to be effective in the treatment of diabetes mellitus and diabetes driven dyslipidemic conditions.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">463</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Gaurav Sharma&lt;sup&gt;1*&lt;/sup&gt;, Sunil Kumar&lt;sup&gt;1&lt;/sup&gt;, Megha Sharma&lt;sup&gt;1&lt;/sup&gt;,&amp;nbsp;Navneet Upadhyay&lt;sup&gt;1&lt;/sup&gt;, Sunil Kumar&lt;sup&gt;2&lt;/sup&gt;, Zabeer Ahmed&lt;sup&gt;3&lt;/sup&gt;, Neeraj Mahindroo&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Pharmaceutical Sciences, Shoolini University, Solan, Himachal Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Medical Parasitology, Post Graduate Institute of Medical Education and Research, Chandigarh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Division of Pharmacology, Indian Institute of Integrative Medicine (CSIR), Jammu, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sunil Kumar</style></author><author><style face="normal" font="default" size="100%">Gaurav Sharma</style></author><author><style face="normal" font="default" size="100%">Amit Kumar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Immunomodulatory Activity of Bioactive Fraction (PBC) from Phyllostachys bambusoides</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Cytokine.</style></keyword><keyword><style  face="normal" font="default" size="100%">Ha Titre</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunostimulation</style></keyword><keyword><style  face="normal" font="default" size="100%">Macrophages</style></keyword><keyword><style  face="normal" font="default" size="100%">Phyllostachys Bambusoides</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/176</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">786-791</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; The lack of vaccines and limitations of currently available strategies demand a need to develop safe and efficacious immunomodulators. &lt;em&gt;Phyllostachys bambusoides&lt;/em&gt; is traditionally used for various autoimmune and infectious disorders, a property possibly attributable to presence of flavonoids like orientin and iso-orientin. &lt;strong&gt;Objective:&lt;/strong&gt; the objective of this study was, to search a potent immunomodulator which elicit both Th1 and Th2 immune response. &lt;strong&gt;Methods:&lt;/strong&gt; The animals were (Balb/c) treated with the bioactive fraction (PBC) from &lt;em&gt;P. bambusoides&lt;/em&gt; (100 and 200 mg/kg body weight) for 14 days with SRBC (Sheep Red Blood Cells) as an antigen. Haemagglutination antibody (HA) titre, delayed type hypersensitivity (DTH) reaction, phagocytic index, NO production, analysis of cytokines in serum and CD80/ CD86 population in spleen. &lt;strong&gt;Results:&lt;/strong&gt; PBC significantly enhanced the expression of IgM and IgG titre and DTH response in a dose dependant manner after 24 and 48 h in BALB/c mice with a maximum response at 200 mg/Kg. Besides humoral and cell mediated immunity, it also enhanced phagocytic index, nitric oxide production, which further leads to protection against &lt;em&gt;Candida albicans&lt;/em&gt; infection. It also, enhanced the expression of CD80 and CD86 in splenic cells. &lt;strong&gt;Conclusion:&lt;/strong&gt; Taken together these i&lt;em&gt;n vitro&lt;/em&gt; and &lt;em&gt;in vivo&lt;/em&gt; data, our results suggest that PBC acts as an effective immunostimulator which specially enhances macrophage function during infection. This further supports the role of PBC in immunopharmacologic applications.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">786</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sunil Kumar&lt;sup&gt;1*&lt;/sup&gt;, Gaurav Sharma&lt;sup&gt;1&lt;/sup&gt;, Amit Kumar&lt;sup&gt;2&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, School of Pharmaceutical Sciences Shoolini University Solan,  Himachal Pradesh 173229, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Indian Institute of Integrative Medicine (CSIR), Jammu 180001, Jammu and
Kashmir, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Bhaskar Sharma</style></author><author><style face="normal" font="default" size="100%">Gaurav Sharma</style></author><author><style face="normal" font="default" size="100%">Suresh Chand Joshi</style></author><author><style face="normal" font="default" size="100%">Sunil Kumar Singh</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">To Evaluate the Antidiabetic and Rejuvenating Capability of Tissues on Alloxan Induced Diabetic Rats under the Effect of Ethanolic Leaf Extract of Coriandrum sativum: A Histopathological Study</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alloxan</style></keyword><keyword><style  face="normal" font="default" size="100%">Coriandrum sativum.</style></keyword><keyword><style  face="normal" font="default" size="100%">Pancreas and Kidney Tissue</style></keyword><keyword><style  face="normal" font="default" size="100%">Wistar Rats</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/177</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">792-798</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; To evaluate the antidiabetic and rejuvenating capability of tissues on alloxan induced diabetic rats under the effect of ethanolic leaf extract of &lt;em&gt;Coriandrum sativum&lt;/em&gt;. &lt;strong&gt;Methods:&lt;/strong&gt; Diabetic model was prepared by administration of alloxan monohydrate (150 mg/ kg i.p). The ethanolic leaf extracts of &lt;em&gt;Coriandrum sativum&lt;/em&gt; at a dose of 200 and 400 mg/kg of body weight were administrated to diabetic induced groups for a period of 28 days. The effect of ethanolic leaf extract of &lt;em&gt;Coriandrum sativum&lt;/em&gt; leaf extract on serum blood glucose, insulin, lipase, &amp;alpha;- amylase and LDH as well as kidney function test [urea, uric acid, albumin, protein and creatinine] were measured in the alloxan induced diabetic rats. &lt;strong&gt;Results:&lt;/strong&gt; In the acute toxicity study, ethanolic leaf extract of &lt;em&gt;Coriandrum sativum&lt;/em&gt; leaf was non-toxic at 2 000 mg/kg in rats. The increased insulin level, albumin and protein level, decreased blood glucose and other biochemical parameters level were observed in diabetic rats treated with both doses of ethanol extract of &lt;em&gt;Coriandrum sativum&lt;/em&gt; leaf compared to diabetic control rats. In Histopathological study were revealed toward normal. &lt;strong&gt;Conclusion:&lt;/strong&gt; Ethanolic extract of &lt;em&gt;Coriandrum sativum&lt;/em&gt; leaf possesses significant antidiabetic and rejuvenating capability of tissues.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">792</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Bhaskar Sharma&lt;sup&gt;1&lt;/sup&gt;, Gaurav Sharma&lt;sup&gt;1*&lt;/sup&gt;, Suresh Chand Joshi&lt;sup&gt;2&lt;/sup&gt;, Sunil Kumar Singh&lt;sup&gt;3&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Sciences , Suresh Gyan Vihar university, Mahal, Jagatpura, Jaipur--302017, Rajasthan, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Reproductive Toxicology Unit, Center for advanced studies, Department of Zoology, University of Rajasthan, Jaipur, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacognosy, United Institute of Pharmacy, Allahabad, Uttar Pradesh, INDIA.&lt;/p&gt;</style></auth-address></record></records></xml>