<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Oluwafemi Adeleke Ojo</style></author><author><style face="normal" font="default" size="100%">Basiru Olaitan Ajiboye</style></author><author><style face="normal" font="default" size="100%">Oluwatosin Debbie Imiere</style></author><author><style face="normal" font="default" size="100%">Oluwatosin Adeyonu</style></author><author><style face="normal" font="default" size="100%">Israel Olayide</style></author><author><style face="normal" font="default" size="100%">Adewale Fadaka</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidative Properties of Blighia sapida K.D. Koenig Stem Bark Extract and Inhibitory Effects on Carbohydrate Hydrolyzing Enzymes Associated with Non-Insulin Dependent Diabetes Mellitus</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Blighia sapida K D Koenig</style></keyword><keyword><style  face="normal" font="default" size="100%">α-amylase</style></keyword><keyword><style  face="normal" font="default" size="100%">α-glucosidase</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/494</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">376-383</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background and Aim:&lt;/strong&gt; In Africa, the fruit, seed, leaf, and stem of &lt;em&gt;Blighia sapida&lt;/em&gt; K.D. Koenig are used as remedy for a range of diseases. This study characterized the phytochemicals, assessed the antioxidant and inhibitory properties of the stem bark of &lt;em&gt;Blighia sapida&lt;/em&gt;. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Samples were consecutively extracted using ethanol solvent and investigated for phenol content, DPPH radical scavenging abilities, iron chelation, reducing power, &amp;alpha;-amylase and &amp;alpha;-glucosidase activities as markers of &lt;em&gt;in vitro&lt;/em&gt; anti-diabetic activities. Phytochemicals were analyzed using gas chromatography-mass spectrometry (GC-MS) analysis. &lt;strong&gt;Results:&lt;/strong&gt; The extract had radical scavenging capabilities, iron chelation and reducing power. Furthermore, the results reveal the extract had considerably high &amp;alpha;-glucosidase and &amp;alpha;- amylase inhibitory activities as the concentration increases with IC&lt;sub&gt;50&lt;/sub&gt; values of 4.17 &amp;plusmn; 0.24 mg/mL and 5.30 &amp;plusmn; 1.25 mg/mL, respectively. Enzyme kinetic studies indicated that the extract displayed uncompetitive inhibitor for &amp;alpha;-glucosidase and was a competitive inhibitor of &amp;alpha;-amylase. The ethanolic extract is rich in several aromatic phenolic compounds and long chain aliphatic acids. &lt;strong&gt;Conclusion:&lt;/strong&gt; These results reveal the bark possessed antioxidant as well as &amp;alpha; -glucosidase and &amp;alpha; -amylase inhibitory activities.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">376</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Oluwafemi Adeleke Ojo*, Basiru Olaitan Ajiboye, Oluwatosin Debbie Imiere, Oluwatosin Adeyonu, Israel Olayide, Adewale Fadaka &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Phytomedicine, Biochemical Toxicology and Diabetes Research Laboratories, Department of Biochemistry, Afe Babalola University, Ado-Ekiti, Ekiti State, NIGERIA.&lt;/p&gt;</style></auth-address></record></records></xml>