<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Regiane Sablina Almeida Bernardes</style></author><author><style face="normal" font="default" size="100%">Sandra Layse Ferreira Sarrazin</style></author><author><style face="normal" font="default" size="100%">Flaviana Alves dos Santos</style></author><author><style face="normal" font="default" size="100%">Moacyr Jesus Barreto de Melo Rêgo</style></author><author><style face="normal" font="default" size="100%">Maira Galdino da Rocha Pitta</style></author><author><style face="normal" font="default" size="100%">Marina Ferraz Cordeiro</style></author><author><style face="normal" font="default" size="100%">Patrícia Danielle Oliveira de Almeida</style></author><author><style face="normal" font="default" size="100%">Ricardo Bezerra de Oliveira</style></author><author><style face="normal" font="default" size="100%">Leoneide Érica Maduro Bouillet</style></author><author><style face="normal" font="default" size="100%">José Guilherme Soares Maia</style></author><author><style face="normal" font="default" size="100%">Rosa Helena Veras Mourão</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant Capacity and Cytotoxicity of the Aqueous Extract of Myrcia guianensis (Aubl.) DC</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Myrtaceae</style></keyword><keyword><style  face="normal" font="default" size="100%">Oxidative stress</style></keyword><keyword><style  face="normal" font="default" size="100%">Pedra-ume-caá</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolic compounds</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">s135-s140</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Ethnobotanical studies report that &lt;em&gt;Myrcia guianensis&lt;/em&gt; (Myrtaceae), belonging to a group of plants known as pedr&amp;aacute;-ume-ca&amp;aacute; or insulin plant, is used as a tea to treat various diseases, including diabetes, a metabolic disorder that leads to the constant production of free radicals. The objective of this work was to determine the antioxidant capacity and the cytotoxicity of the AEMg. &lt;strong&gt;Methods:&lt;/strong&gt; The content of phenolic compounds in AEMg was determined by colorimetric assays. &lt;em&gt;In vitro&lt;/em&gt; tests of the antioxidant capacity of AEMg, in the sequestration of DPPH radicals, in &amp;beta;-carotene bleaching, in the FRAP, as well as in human fibroblast cells of the MRC-5 lineage, were performed. The cytotoxic activity of AEMg was evaluated in assays with eukaryotic cells from yeast &lt;em&gt;Saccharomyces cerevisiae&lt;/em&gt; and in PBMC. &lt;strong&gt;Results:&lt;/strong&gt; The results showed that the AEMg is rich in phenolic compounds, presenting high antioxidant potential in all the tests carried out, including in human fibroblast cells of the MRC-5 lineage, besides not being toxic to eukaryotic cells. &lt;strong&gt;Conclusion&lt;/strong&gt;: The AEMg, rich in antioxidant compounds and no toxicity, can be used as source of natural antioxidant in the treatment of metabolic diseases to combat free radicals.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s135</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Regiane Sablina Almeida Bernardes&lt;sup&gt;1,2&lt;/sup&gt;, Sandra Layse Ferreira Sarrazin&lt;sup&gt;2&lt;/sup&gt;, Flaviana Alves dos Santos&lt;sup&gt;4&lt;/sup&gt;, Moacyr Jesus Barreto de Melo R&amp;ecirc;go&lt;sup&gt;4&lt;/sup&gt;, Maira Galdino da Rocha Pitta&lt;sup&gt;4&lt;/sup&gt;, Marina Ferraz Cordeiro&lt;sup&gt;5&lt;/sup&gt;, Patr&amp;iacute;cia Danielle Oliveira de Almeida&lt;sup&gt;6&lt;/sup&gt;, Ricardo Bezerra de Oliveira&lt;sup&gt;2&lt;/sup&gt;, Leoneide &amp;Eacute;rica Maduro Bouillet&lt;sup&gt;2&lt;/sup&gt;, Jos&amp;eacute; Guilherme Soares Maia&lt;sup&gt;3&lt;/sup&gt;, Rosa Helena Veras Mour&amp;atilde;o&lt;sup&gt;1,2,3*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Programa de P&amp;oacute;s-Gradua&amp;ccedil;&amp;atilde;o em Biodiversidade e Biotecnologia da Amaz&amp;ocirc;nia Legal (Bionorte), Universidade Federal do Amazonas, 60077-000 Manaus, AM, BRAZIL.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt; 2&lt;/sup&gt;Laborat&amp;oacute;rio de Bioprospec&amp;ccedil;&amp;atilde;o e Biologia Experimental, Universidade Federal do Oeste do Par&amp;aacute;, 68135-110 Santar&amp;eacute;m, PA, BRAZIL.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Programa de P&amp;oacute;s-Gradua&amp;ccedil;&amp;atilde;o em Recursos Naturais da Amaz&amp;ocirc;nia, Universidade Federal do Oeste do Par&amp;aacute;, 68135-110 Santar&amp;eacute;m, PA, BRAZIL.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt; 4&lt;/sup&gt;N&amp;uacute;cleo de Pesquisa para Inova&amp;ccedil;&amp;atilde;o Terap&amp;ecirc;utica Suely Galdino, Universidade Federal de Pernambuco, 50670- 901 Recife, PE, BRAZIL.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Universidade Federal do Vale do S&amp;atilde;o Francisco, Colegiado de Medicina, Campus Paulo Afonso, 48607-190, BA, BRAZIL.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Universidade Federal do Amazonas, Laborat&amp;oacute;rio de Atividade Biol&amp;oacute;gica, 60077-000 Manaus, AM, BRAZIL.&lt;/p&gt;</style></auth-address></record></records></xml>