<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rattazart Denchai</style></author><author><style face="normal" font="default" size="100%">Somsak Nualkaew</style></author><author><style face="normal" font="default" size="100%">Pornpun Laovachirasuwan</style></author><author><style face="normal" font="default" size="100%">Nopphawan Pornsiri</style></author><author><style face="normal" font="default" size="100%">Chonlada Judprakop</style></author><author><style face="normal" font="default" size="100%">Surapong Rattana</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-inflammatory Activity, Toxicity Assessment and GC-MS Chemical Profiling of Cha-Nu-Ruk Traditional Thai Herbal Poultice for Knee Pain Management</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory</style></keyword><keyword><style  face="normal" font="default" size="100%">GC-MS</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal poultice</style></keyword><keyword><style  face="normal" font="default" size="100%">Knee pain</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemistry</style></keyword><keyword><style  face="normal" font="default" size="100%">Thai traditional medicine</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2026</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2026</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">18</style></volume><pages><style face="normal" font="default" size="100%">31-35</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Thai Traditional herbal medicine employs multi-herb formulations for managing inflammatory conditions. This study investigates the anti-inflammatory properties, cytotoxicity, and chemical composition of Cha-Nu-Ruk, an eight-herb traditional poultice formulation for knee pain. &lt;strong&gt;Methods:&lt;/strong&gt; Eight medicinal plants (&lt;em&gt;Tiliacora triandra, Thunbergia laurifolia, Azadirachta indica, Clinacanthus nutans, Pandanus amaryllifolius, Justicia gendarussa, Sida acuta,&lt;/em&gt; and &lt;em&gt;Zingiber cassumunar&lt;/em&gt;) were extracted with 70% ethanol. Anti-inflammatory activity was evaluated through nitric oxide inhibition assay using Jurkat cells. Cytotoxicity was assessed via MTT assay. Chemical profiling employed GC-MS analysis. &lt;strong&gt;Results: &lt;/strong&gt;Individual plant extracts demonstrated variable anti-inflammatory activity (NO inhibition: 28.52-73.80%) with &lt;em&gt;Clinacanthus nutans &lt;/em&gt;showing highest potency. The combined eight-herb formulation yielded 11.82±0.41% extraction efficiency with 26.2% NO inhibition. GC-MS analysis identified 21 compounds, with DMPBD (19.13% relative abundance) and β-sitosterol (1.13%). Cytotoxicity evaluation revealed acceptable safety profiles (&amp;gt;80% cell viability) for most extracts. &lt;strong&gt;Conclusions:&lt;/strong&gt; While individual herbs showed promising anti-inflammatory potential, the traditional eight-herb combination did not demonstrate synergistic enhancement. Chemical standardization revealed significant batch-to-batch variability, highlighting the need for optimized formulation ratios and quality control protocols.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">31</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Rattazart Denchai&lt;sup&gt;1&lt;/sup&gt;, Somsak Nualkaew&lt;sup&gt;2&lt;/sup&gt;, Pornpun Laovachirasuwan&lt;sup&gt;2&lt;/sup&gt;, Nopphawan Pornsiri&lt;sup&gt;3&lt;/sup&gt;, Chonlada Judprakop4, Surapong Rattana&lt;sup&gt;5*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Thai Traditional Medicine, Faculty of Science, Ramkhamhaeng University, Bangkok, 10240, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Pharmaceutical Chemistry and Natural Product Research Unit, Faculty of Pharmacy, Mahasarakham University, Maha Sarakham, 44150, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Applied Thai Traditional Medicine, Faculty of Science and Technology, Phanakhon Rajabhat University, Bangkok, 10220, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Faculty of Pharmacy, Nakhonratchasima College, Nakhon Ratchasima, 30000, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Division of Science, Faculty of Education, Nakhon Phanom University, Nakhon Phanom, 48000, THAILAND.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sawitree Wongtangtintharn</style></author><author><style face="normal" font="default" size="100%">Sirirath McCloskey</style></author><author><style face="normal" font="default" size="100%">Rungruedee Thiwthong</style></author><author><style face="normal" font="default" size="100%">U-sa Thongpairoj</style></author><author><style face="normal" font="default" size="100%">Surapong Rattana</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Free Radical Scavenging and Anticancer Activities of Methanolic Twig Extract of Annonaceae Plant</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Annonaceae</style></keyword><keyword><style  face="normal" font="default" size="100%">Anticancer</style></keyword><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Cancer cell selectivity</style></keyword><keyword><style  face="normal" font="default" size="100%">DPPH assay</style></keyword><keyword><style  face="normal" font="default" size="100%">Goniothalamus elegans</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">362-365</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; The Annonaceae family represents a promising source of bioactive compounds with potential therapeutic applications. This study aimed to comprehensively evaluate the antioxidant and anticancer potential of methanolic twig extracts from seven Annonaceae species. &lt;strong&gt;Methods: &lt;/strong&gt;Twig specimens from &lt;em&gt;Cananga latifolia, Goniothalamus elegans, Goniothalamus tamirensis, Melodorum fructicosum, Polyalthia dubia, Polyalthia cerasoides&lt;/em&gt;, and &lt;em&gt;Uvaria fauveliana&lt;/em&gt; were subjected to standardized methanolic extraction. Antioxidant activity was assessed using DPPH radical scavenging assay. Anticancer potential was evaluated through Sulforhodamine B assay against three human cancer cell lines and normal human dermal fibroblasts at 25 μg/mL concentration. &lt;strong&gt;Results:&lt;/strong&gt; &lt;em&gt;Goniothalamus elegans&lt;/em&gt; demonstrated exceptional antioxidant activity (IC50 = 5.62 ± 1.21 μg/mL) comparable to ascorbic acid. In anticancer evaluation, &lt;em&gt;G. elegans &lt;/em&gt;exhibited remarkable cytotoxicity against MCF-7 (95.19 ± 0.62%) and HeLa (94.46 ± 1.69%) cancer cells while demonstrating exceptional selectivity with minimal toxicity toward normal cells (19.72 ± 1.19%). Melodorum fructicosum showed highest activity against HT-29 colon cancer cells (75.84 ± 1.57%). &lt;strong&gt;Conclusions:&lt;/strong&gt; &lt;em&gt;Goniothalamus elegans&lt;/em&gt; demonstrated exceptional dual bioactivity with both potent antioxidant properties and selective anticancer effects. The remarkable selectivity indices and broad-spectrum anticancer activity suggest significant clinical potential. These findings provide scientific validation for traditional medicinal uses of Annonaceae species.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">362</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sawitree Wongtangtintharn&lt;sup&gt;1&lt;/sup&gt;, Sirirath McCloskey&lt;sup&gt;2&lt;/sup&gt;, Rungruedee Thiwthong&lt;sup&gt;3&lt;/sup&gt;, U-sa Thongpairoj&lt;sup&gt;3&lt;/sup&gt;, Surapong Rattana&lt;sup&gt;4*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Animal Science, Faculty of Agriculture, Khon Kaen University, Khon Kaen, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biology, Faculty of Science, Mahasarakham University, Maha Sarakham, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Division of Science, Faculty of Education, Nakhon Phanom University, Nakhon Phanom, THAILAND.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ladachart Taepongsorat</style></author><author><style face="normal" font="default" size="100%">Surapong Rattana</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant Activities of Ethanolic and Aqueous Extracts of Asparagus racemosus Roots</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Asparagus racemosus</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoid</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolic compound</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">1129-1132</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; &lt;em&gt;Asparagus racemosus&lt;/em&gt; (AR) is commonly known as shatavari, satawar or satmuli in India and in Thailand it is call sam-sib or rak-sam-sib. The dried root of AR is used in Ayurveda as an antiulcerous and antiinflammatory and has medicinal/pharmacological value. &lt;strong&gt;Objective:&lt;/strong&gt; To investigate the antioxidant activities of &lt;em&gt;Asparagus racemosus&lt;/em&gt; root extracts via total phenolic and total flavonoid contents of ethanolic and aqueous extracts. Methods: Antioxidant capacity measurements were carried out by DPPH, ABTS and FRAP methods. Total phenolic and flavonoid contents were determined by the Folin-Ciocalteu method and the aluminum chloride colorimetric method, respectively. &lt;strong&gt;Results:&lt;/strong&gt; The ethanolic extract possessed higher antioxidant capacities than the aqueous extract in the three antioxidant assays (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05).These results have shown high phenolic and flavonoid contents. The ethanolic extract of AR root possessed higher amounts of phenolic and flavonoid contents than the aqueous extract.&lt;strong&gt; Conclusion:&lt;/strong&gt; The antioxidant capacity of the ethanolic extract was higher than that in the aqueous extract.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1129</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Ladachart Taepongsorat&lt;sup&gt;1,*&lt;/sup&gt;, Surapong Rattana&lt;sup&gt;2, 3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Medicine, Mahasarakham University, Mahasarakham 44000, THAILAND.&lt;/p&gt;
&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Pharmaceutical Chemistry and Natural Products Research Unit, Faculty of Pharmacy, Mahasarakham University, Mahasarakham 44150, THAILAND.&lt;/p&gt;
&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Division of Science Education, Faculty of Education, Nakhon Phanom University, Nakhon Phanom 48000, THAILAND.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Surapong Rattana</style></author><author><style face="normal" font="default" size="100%">Teeraporn Katisart</style></author><author><style face="normal" font="default" size="100%">Bunleu Sungthong</style></author><author><style face="normal" font="default" size="100%">Chirapha Butiman</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Acute and Sub-acute Toxicities of Thai Silkworm Powder (Bombyx mori Linn.) From Three Races in Male Wistar Rats and In vitro Antioxidant Activities</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">antioxidant activities.</style></keyword><keyword><style  face="normal" font="default" size="100%">hematological parameters</style></keyword><keyword><style  face="normal" font="default" size="100%">lipid profile</style></keyword><keyword><style  face="normal" font="default" size="100%">Silkworm</style></keyword><keyword><style  face="normal" font="default" size="100%">toxicities</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">/files/PJ-9-4/10.5530pj.2017.4.87</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">541-545</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; The silkworm powder from Japanese and Korean races has a high biological activity. However, there was less scientific evidence regarding bioactivities in Thai silkworm races. &lt;strong&gt;Objective:&lt;/strong&gt; This research was interested in toxicity and antioxidant activities of Thai silkworm races. &lt;strong&gt;Material and methods:&lt;/strong&gt; The 5th instar, 3rd day of growth stage of Thai traditional silkworm (Nanglai, Nangnoi and Samrong races) were lyophilized by freeze dryer and ground as silkworm powder. The acute and sub-acute toxicities studies were carried out in male Wistar rats. The antioxidant capacities of silkworm powder were investigated with DPPH, ABTS and FRAP methods. &lt;strong&gt;Results:&lt;/strong&gt; The acute toxicity in rats by single dose oral administration show that the high dose at a concentration of 2,000 mg/kg b.w. did not have toxicity in rats. The sub-acute toxicity in rats by oral administration showed that the high dose concentration at 2,000 mg/kg body weight for 6 weeks had no toxicity in all group either. In addition, the hematological parameters and lipid profiles of treated group and control groups were not significantly different. The antioxidant study showed that silkworm powders were not significant difference in all groups of samples in three assays (DPPH, ABTS and FRAP). However, significant difference had been found in comparison to ascorbic acid (p &amp;lt; 0.05). &lt;strong&gt;Conclusion:&lt;/strong&gt; Silkworm powder from three races of Thai silkworm did not produce any toxicity in male rats. In addition, the silkworm powder also exhibited antioxidant activities.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">541</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Surapong Rattana&lt;sup&gt;1&lt;/sup&gt;*, Teeraporn Katisart&lt;sup&gt;2&lt;/sup&gt;, Bunleu Sungthong&lt;sup&gt;3&lt;/sup&gt;, Chirapha Butiman&lt;sup&gt;4 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biology, Faculty of Science, Mahasarakham University, Maha Sarakham, 44150, THAILAND.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biology, Faculty of Science, Mahasarakham University, Maha Sarakham, 44150, THAILAND.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Pharmaceutical Chemistry and Natural Products Research Unit, Faculty of Pharmacy, Mahasarakham University, Maha Sarakham, 44150, THAILAND.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Silk Innovation Center, Mahasarakham University, Maha Sarakham, 44150, THAILAND.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Surapong Rattana</style></author><author><style face="normal" font="default" size="100%">Teeraporn Katisart</style></author><author><style face="normal" font="default" size="100%">Chirapha Butiman</style></author><author><style face="normal" font="default" size="100%">Bunleu Sungthong</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antihyperglycemic Effect of Silkworm Powder, Fibroin and Sericin from Three Thai Silkworm (Bombyx mori Linn.) in Streptozotocin-Induced Diabetic Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antihyperglycemic effect</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetic rats</style></keyword><keyword><style  face="normal" font="default" size="100%">Fibroin.</style></keyword><keyword><style  face="normal" font="default" size="100%">Sericin</style></keyword><keyword><style  face="normal" font="default" size="100%">Silkworm</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">/files/PJ-9-4/10.5530pj.2017.4.89</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">559-564</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The present study was aimed to investigate the antihyperglycemic activities of Thai silkworm (&lt;em&gt;Bombyx mori &lt;/em&gt;Linn.) powder, fibroin and sericin from three races of Thai silkworm including Nangnoi, Nanglai, and Samrong in streptozotocin-induced diabetic rats. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; All rats were daily and orally administered with silkworm powder (5&lt;sup&gt;th&lt;/sup&gt;-instar, 3&lt;sup&gt;rd&lt;/sup&gt;-day), fibroin, and sericin at a dose of 250 mg/kg for 6 weeks. After that, various parameters including body weight, blood glucose, hematological and biochemical parameters were determined. &lt;strong&gt;Results:&lt;/strong&gt; The results revealed that fasting plasma glucose level in 6&lt;sup&gt;th&lt;/sup&gt; week of Nanglai fibroin, Nangnoi fibroin and Nangnoi sericin expressed a better reduction of FPG in diabetic rats compared with diabetic control groups (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05). All hematological parameters of each group were not different within those values (&lt;em&gt;p&lt;/em&gt;&amp;gt;0.05). In case of blood urea nitrogen, creatinine and alkaline phosphatase value showed that some of treated groups was different from diabetic control (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05), while all of treated groups showed different in cholesterol and high density lipoprotein value (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05). &lt;strong&gt;Conclusion:&lt;/strong&gt; Silkworm powders, fibroin and sericin of three races exhibited a therapeutic potential for the reduction plasma glucose level. Treatments of silkworm powder, fibroin and sericin did not have any effect on hematological parameters. Improvement of blood urea nitrogen, creatinine, alkaline phosphatase values and lipid profiles also were also observed in the treatment groups.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">559</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Surapong Rattana&lt;sup&gt;1*&lt;/sup&gt;, Teeraporn Katisart&lt;sup&gt;2&lt;/sup&gt;, Chirapha Butiman&lt;sup&gt;3&lt;/sup&gt;, Bunleu Sungthong&lt;sup&gt;4 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;em&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biology, Faculty of Science, Mahasarakham University, Maha Sarakham, 44150, THAILAND. &lt;/em&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;em&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biology, Faculty of Science, Mahasarakham University, Maha Sarakham, 44150, THAILAND. &lt;/em&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;em&gt;&lt;sup&gt;3&lt;/sup&gt;Silk Innovation Center, Mahasarakham University, Maha Sarakham, 44150, THAILAND. &lt;/em&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;em&gt;&lt;sup&gt;4&lt;/sup&gt;Pharmaceutical Chemistry and Natural Products Research Unit, Faculty of Pharmacy, Mahasarakham University, Maha Sarakham, 44150, THAILAND.&lt;/em&gt;&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Teeraporn Katisart</style></author><author><style face="normal" font="default" size="100%">Surapong Rattana</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hypoglycemic Activity of Leaf Extracts from Tiliacora triandra in Normal and Streptozotocin-Induced Diabetic Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Hypoglycemic Effect</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin-Induced Diabetic Rats.</style></keyword><keyword><style  face="normal" font="default" size="100%">Tiliacora triandra</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">/files/pj-9-5/10.5530pj.2017.5.99/index.html</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">621-625</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; &lt;em&gt;Tiliacora triandra&lt;/em&gt; is a common plant found in southeast Asian countries. It is traditionally used as anti-pyrogenic agent. &lt;strong&gt;Objective:&lt;/strong&gt; The present study was aimed to investigate the hypoglycemic activities leaf extracts from &lt;em&gt;Tiliacora triandra&lt;/em&gt; (TTE) in normal and streptozotocin- induced diabetic rats. &lt;strong&gt;Methods:&lt;/strong&gt; TTE was prepared and daily and orally administered at dose of 300 mg/kg b.w. to the rats for 8 weeks. The body weight and blood glucose level were measured weekly. At the end of the experiments, blood samples were collected from cardiac puncture and analyzed for serum insulin levels. The pancreatic tissues were stained by hematoxylin-eosin for histo-pathological investigations. &lt;strong&gt;Results:&lt;/strong&gt; Normal and diabetic rats treated with TTE and glibenclamide tended to have an increased body weight. TTE significantly decreased the blood glucose level by 25.01 &amp;plusmn; 19.77% in week 3 in diabetic rats and similar to that of glibenclamide group (27.01 &amp;plusmn; 11.89%). However, the extracts slightly decreased the blood glucose level in normal rats by 9.48 &amp;plusmn; 2.14% in week 2. TTE significantly increased serum insulin level by 21.63 &amp;plusmn; 1.39 IU/mL in diabetic rats compared to the controls (10.63 &amp;plusmn; 0.37 IU/mL) but not in normal rats. In additions, TTE activated the regeneration of pancreatic Islets of Langerhans in diabetic rats which in turn stimulated insulin secretion. &lt;strong&gt;Conclusion:&lt;/strong&gt; TTE exhibits the hypoglycemic potential by stimulating insulin secretion from the pancreas.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">621</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Teeraporn Katisart&lt;sup&gt;1*&lt;/sup&gt;, Surapong Rattana&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biology, Faculty of Science, Mahasarakham University, THAILAND&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Pharmaceutical chemistry and Natural Products Research Unit, Faculty of Pharmacy, Mahasarakham University, THAILAND&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Surapong Rattana</style></author><author><style face="normal" font="default" size="100%">Benjamart Cushnie</style></author><author><style face="normal" font="default" size="100%">Ladachart Taepongsorat</style></author><author><style face="normal" font="default" size="100%">Methin Phadungkit</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Chemical Constituents and in vitro anticancer activity of  Tiliacora triandra leaves</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">In vitro anticancer activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Oxoanolobine</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemistry</style></keyword><keyword><style  face="normal" font="default" size="100%">Tiliacora triandra</style></keyword><keyword><style  face="normal" font="default" size="100%">Yanang.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">09/2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">1-3</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction&lt;/strong&gt;: &lt;em&gt;&amp;nbsp;Tiliacora triandra&lt;/em&gt; (F. &lt;em&gt;Menispermaceae&lt;/em&gt;) is edible and is also known for medicinal values. The leaves are a popular flavoring in Southeast Asia, especially in the northeast of Thailand.&amp;nbsp; The objectives of this study were to determine the major constituents of the leaves of &lt;em&gt;T. triandra&lt;/em&gt;, and assess their anticancer activities against human cancer cell lines. &lt;strong&gt;Methods&lt;/strong&gt;: The leaves were extracted by a soxhlet apparatus with petroleum ether, dichloromethane, ethyl acetate and water. Major constituents were then purified and identified using chromatographic procedures and various spectroscopic techniques.&amp;nbsp; &lt;em&gt;In vitro&lt;/em&gt; anticancer activity tests of &lt;em&gt;T. triandra&lt;/em&gt; extracts were performed by resazurinmicroplate assay (REMA), and tested with 3 cell lines: oral cavity cancer (KB), lung cancer (NCI-H187) and breast cancer (MCF-7) cell lines. &lt;strong&gt;Results&lt;/strong&gt;: The result indicated that the main compound of &lt;em&gt;T. triandra&lt;/em&gt; leaves was oxoanolobine. The methanol extract showed the highest cytotoxic activity against lung cancer (NCI-H187) cell line whereas the water extract exhibited the highest activity against oral cavity cancer (KB) cell line. The IC&lt;sub&gt;50&lt;/sub&gt; of oxoanolobine against the NCI-H187 cell line was 27.60 &amp;plusmn; 4.30 &amp;micro;g/mL. &lt;strong&gt;Conclusion:&lt;/strong&gt;&amp;nbsp; &lt;em&gt;T. triandra&lt;/em&gt; leaves contain oxoanolobine as the major constituent and have the potential of anticancer activity but are required to be investigated further.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Surapong Rattana&lt;sup&gt;1&lt;/sup&gt;, Benjamart Cushnie&lt;sup&gt;2&lt;/sup&gt;, Ladachart Taepongsorat&lt;sup&gt;3&lt;/sup&gt; and Methin Phadungkit&lt;sup&gt;4*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Science, Mahasarakham University, Kantarawichai, Maha Sarakham-44150, Thailand.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2,4&lt;/sup&gt;Faculty of Pharmacy, Mahasarakham University, Kantarawichai, Maha Sarakham-44150, Thailand.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Faculty of Medicine, Mahasarakham University, Meuang, MahaSarakham-44000, Thailand.&lt;/p&gt;</style></auth-address></record></records></xml>