<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dennis R.A. Mans</style></author><author><style face="normal" font="default" size="100%">Terrence Mawie</style></author><author><style face="normal" font="default" size="100%">Priscilla Friperson</style></author><author><style face="normal" font="default" size="100%">Meryll Djotaroeno</style></author><author><style face="normal" font="default" size="100%">Jennifer Pawirodihardjo</style></author><author><style face="normal" font="default" size="100%">Vinoj H. Sewberath Misser</style></author><author><style face="normal" font="default" size="100%">Ed P.F. Ijzerman</style></author><author><style face="normal" font="default" size="100%">Walther Jap Tjoen San</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">In vitro Platelet Aggregation-Stimulatory, Antibacterial, and Cytotoxic Activities of the Fresh Stem Juice from Montrichardia arborescens Schott (Araceae) – Evidence for Wound Healing- Stimulatory Properties</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Broth microdilution</style></keyword><keyword><style  face="normal" font="default" size="100%">In vitro studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Lack of cytotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Montrichardia arborescens Schott</style></keyword><keyword><style  face="normal" font="default" size="100%">MTT Assay</style></keyword><keyword><style  face="normal" font="default" size="100%">Platelet aggregation stimulation</style></keyword><keyword><style  face="normal" font="default" size="100%">Preliminary Antibacterial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">PRP</style></keyword><keyword><style  face="normal" font="default" size="100%">Stem juice</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">299-306</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Montrichardia arborescens&lt;/em&gt; is traditionally used for wound healing, but without scientific evidence. In this study, the fresh stem juice was assessed for its platelet aggregation stimulatory and antibacterial activities and its safety. &lt;strong&gt;Methods: &lt;/strong&gt;The stem juice was evaluated at various dilutions for platelet aggregation-stimulatory activity in human platelet rich plasma (PRP) using norepinephrine as a positive control; antibacterial activity against &lt;em&gt;Staphylococcus aureus&lt;/em&gt; and &lt;em&gt;Streptococcus pyogenes&lt;/em&gt; (gram-positive bacteria) as well as &lt;em&gt;Escherichia coli&lt;/em&gt; and Pseudomonas aeruginosa (gram-negative bacteria) in a broth microdilution method using tetracycline as a reference compound; and absence of substantial cytotoxicity against cultured CHO cells in an MTT assay. Data (means ± SDs; n ≥ 3) were evaluated for statistically significant differences (p &amp;lt; 0.05) using ANOVA with Bonferroni’s adjustments. &lt;strong&gt;Results: &lt;/strong&gt;The stem juice stimulated platelet aggregation to nearly 100% at 50% (&lt;em&gt;v/v&lt;/em&gt;) dilution and about 50% at 12.5% (&lt;em&gt;v/v&lt;/em&gt;) dilution. It did not affect the growth of &lt;em&gt;E. coli &lt;/em&gt;and &lt;em&gt;P. aeruginosa&lt;/em&gt; at 50% (&lt;em&gt;v/v&lt;/em&gt;) but partially inhibited that of &lt;em&gt;S. aureus&lt;/em&gt; at 37.5% (&lt;em&gt;v/v&lt;/em&gt;) and that of &lt;em&gt;S. pyogenes&lt;/em&gt; completely at 12.5% (&lt;em&gt;v/v&lt;/em&gt;). These effects were validated by those found with epinephrine 20 μM and tetracycline 10-60 μg/mL. CHO cell survival was only 3 ± 1% with the 50% (&lt;em&gt;v/v&lt;/em&gt;) diluted stem juice but 64 ± 2% with the 12.5% (v/v) dilution. &lt;strong&gt;Conclusion: &lt;/strong&gt;The &lt;em&gt;M. arborescens&lt;/em&gt; stem juice exhibited substantial platelet aggregation-stimulatory and antibacterial activity at 12.5% (&lt;em&gt;v/v&lt;/em&gt;) dilution which seemed safe to the normal tissues. These findings confirm its traditional use for wound healing.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">299</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Dennis R.A. Mans&lt;sup&gt;1*&lt;/sup&gt;, Terrence Mawie&lt;sup&gt;2&lt;/sup&gt;, Priscilla Friperson&lt;sup&gt;1&lt;/sup&gt;, Meryll Djotaroeno&lt;sup&gt;1&lt;/sup&gt;, Jennifer Pawirodihardjo&lt;sup&gt;1&lt;/sup&gt;, Vinoj H. Sewberath Misser&lt;sup&gt;1&lt;/sup&gt;, Ed P.F. Ijzerman&lt;sup&gt;2&lt;/sup&gt;, Walther Jap Tjoen San&lt;sup&gt;3&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, Faculty of Medical Sciences, Anton de Kom University of Suriname, Paramaribo, SURINAME.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Medical Microbiology, Academic Hospital Paramaribo, Paramaribo, SURINAME.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Cardiology, Academic Hospital Paramaribo, Paramaribo, SURINAME.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dennis R.A. Mans</style></author><author><style face="normal" font="default" size="100%">Priscilla Friperson</style></author><author><style face="normal" font="default" size="100%">Meryll Djotaroeno</style></author><author><style face="normal" font="default" size="100%">Vinoj Sewberath Misser</style></author><author><style face="normal" font="default" size="100%">Jennifer Pawirodihardjo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">In vitro Anti-inflammatory and Antioxidant Activities as well as Phytochemical Content of the Fresh Stem Juice from Montrichardia arborescens Schott (Araceae)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory activity</style></keyword><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">In vitro studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Montrichardia arborescens Schott</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical content</style></keyword><keyword><style  face="normal" font="default" size="100%">Stem juice</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">296-304</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;em&gt; &lt;/em&gt;&lt;/strong&gt;&lt;em&gt;Montrichardia arborescens&lt;/em&gt; Schott (Araceae) is traditionally used for treating, among others, inflammatory conditions, but so far without scientific evidence. In this study, the fresh stem juice was assessed for its anti-inflammatory and antioxidant activities and phytochemical content. &lt;strong&gt;Methods:&lt;/strong&gt; The stem juice’s anti-inflammatory activity was evaluated using a heat-induced bovine serum albumin (BSA) denaturation assay and a hypotonicity-induced human erythrocyte membrane lysis assay. Its antioxidant activity was determined by a DPPH free radical-scavenging assay and a FRAP assay. Diclofenac and Trolox were used as reference compounds. Its phytochemical content was qualitatively explored by standard methods. Data (means ± SDs; n ≥ 3) were evaluated for statistically significant differences (p &amp;lt; 0.05) using ANOVA with Bonferroni post hoc adjustments. &lt;strong&gt;Results:&lt;/strong&gt; At ≥ 12.5% (v/v), the stem juice inhibited BSA denaturation by 50%-75% and membrane lysis by roughly 90%. At 0.20-7.0% (v/v), it did not affect BSA denaturation but stabilized membranes by &amp;gt; 50%. The juice scavenged DPPH free radicals at an EC&lt;sub&gt;50 &lt;/sub&gt;of 2.0 ± 0.2% (v/v) and achieved at that dilution an antioxidant power of 2,616 ± 16 μM Fe&lt;sup&gt;2+&lt;/sup&gt; equivalents. All the effects were in the range of those found with diclofenac 50 μg/mL and Trolox 1.0-6.0 μg/mL. The stem juice contained phenolic compounds, flavonoids, tannins, alkaloids, saponins, and glycosides. &lt;strong&gt;Conclusion:&lt;/strong&gt; The &lt;em&gt;M. arborescens s&lt;/em&gt;tem juice exhibited appreciable anti-inflammatory activities that might mainly be associated with the inhibition of the release of inflammatory mediators, along with notable antioxidant activity, which might be attributable to phytochemicals with known anti-inflammatory and antioxidant properties.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><accession-num><style face="normal" font="default" size="100%">07</style></accession-num><section><style face="normal" font="default" size="100%">296</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Dennis R.A. Mans*, Priscilla Friperson, Meryll Djotaroeno, Vinoj Sewberath Misser, Jennifer Pawirodihardjo&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Pharmacology, Faculty of Medical Sciences, Anton de Kom University of Suriname, Paramaribo, SURINAME.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dennis RA Mans</style></author><author><style face="normal" font="default" size="100%">Meryll Djotaroeno</style></author><author><style face="normal" font="default" size="100%">Priscilla Friperson</style></author><author><style face="normal" font="default" size="100%">Jennifer Pawirodihardjo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phytochemical and Pharmacological Support for the Traditional Uses of Zingiberacea Species in Suriname - A Review of the Literature</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Pharmacological activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical composition</style></keyword><keyword><style  face="normal" font="default" size="100%">Rationale</style></keyword><keyword><style  face="normal" font="default" size="100%">Suriname</style></keyword><keyword><style  face="normal" font="default" size="100%">Traditional uses</style></keyword><keyword><style  face="normal" font="default" size="100%">Zingiberaceae</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1511-1525</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The &lt;em&gt;Zingiberacea&lt;/em&gt; or ginger family is a family of flowering plants comprising roughly 1,600 species of aromatic perennial herbs with creeping horizontal or tuberous rhizomes divided into about 50 genera. The &lt;em&gt;Zingiberaceae &lt;/em&gt;are distributed throughout tropical Africa, Asia, and the Americas. Many members are economically important as spices, ornamentals, cosmetics, traditional medicines, and/or ingredients of religious rituals. One of the most prominent characteristics of this plant family is the presence of essential oils in particularly the rhizomes but in some cases also the leaves and other parts of the plant. The essential oils are in general made up of a variety of, among others, terpenoid and phenolic compounds with important biological activities. The Republic of Suriname (South America) is well-known for its ethnic and cultural diversity as well as its extensive ethnopharmacological knowledge and unique plant biodiversity. This paper first presents some general information on the &lt;em&gt;Zingiberacea &lt;/em&gt;family, subsequently provides some background about Suriname and the &lt;em&gt;Zingiberacea&lt;/em&gt; species in the country, then extensively addresses the traditional uses of one representative of the seven genera in the country and provides the phytochemical and pharmacological support for these uses, and concludes with a critical appraisal of the medicinal values of these plants.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1511</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Dennis RA Mans*, Meryll Djotaroeno, Priscilla Friperson, Jennifer Pawirodihardjo&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Pharmacology, Faculty of Medical Sciences, Anton de Kom University of Suriname, Paramaribo, SURINAME.&lt;/p&gt;
</style></auth-address></record></records></xml>