<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nithya Venugopal</style></author><author><style face="normal" font="default" size="100%">Radhika Jayaraman</style></author><author><style face="normal" font="default" size="100%">Mohammed Junaid Hussain Dowlath</style></author><author><style face="normal" font="default" size="100%">Ganesh Munuswamy Ramanujam</style></author><author><style face="normal" font="default" size="100%">Sundarapandian Subramaniyan</style></author><author><style face="normal" font="default" size="100%">Pratheepa Sivasankari Natarajan</style></author><author><style face="normal" font="default" size="100%">Jayashri Seetharaman</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comprehensive Analysis of Brassica oleracea: Phytochemical Composition, Radical Scavenging, and Anti-Proliferative Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidants</style></keyword><keyword><style  face="normal" font="default" size="100%">Broccoli</style></keyword><keyword><style  face="normal" font="default" size="100%">DPPH</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoids</style></keyword><keyword><style  face="normal" font="default" size="100%">FTIR</style></keyword><keyword><style  face="normal" font="default" size="100%">ROS</style></keyword><keyword><style  face="normal" font="default" size="100%">THP-1 cells</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">293-298</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Natural sources like plants, vegetables, and fruits contain vast micro and macro nutrients that are useful for livelihood and also act as a medicine for various health conditions. &lt;em&gt;Brassica &lt;/em&gt;vegetable naturally contains high antioxidant property which aids in removing free radicals caused by organelles during cellular process. The study aims at preparing &lt;em&gt;Brassica oleracea&lt;/em&gt; extracts using a range of polar and non-polar solvents and to evaluate its phytochemical, antioxidant and cytotoxicity properties. &lt;strong&gt;Methods: &lt;/strong&gt;&lt;em&gt;Brassica oleracea&lt;/em&gt; was extracted using hexane, ethyl acetate and ethanol. All the extracts were subjected to phytochemical analysis and antioxidant activity was performed using DPPH method. The antiproliferative activity was perfomed on THP-1 cells by MTT assay. The extract showing maximum activity was then characterized using FTIR and GCMS. &lt;strong&gt;Results: &lt;/strong&gt;The extract study infers positive results for major secondary metabolites (alkaloids, glycosides, proteins, phenols, tannins, steroids, flavonoids, terpenoids and diterpenes) and negative for quinones and coumarins. DPPH radical scavenging assay showed high antioxidant activity for ethanol extracts 45-91% at 5μg/mL followed by ethyl acetate (37%-80%) and hexane extract (23%-73%). The anti-proliferative activity in THP-1 cells, revealed that the ethanolic extract significantly decreases cell viability relative to hexane and ethyl acetate extracts, indicating its potential as a natural anticancer drug. &lt;strong&gt;Conclusion: &lt;/strong&gt;Cytotoxicity studies further demonstrated a concentration dependent effect on cell viability, indicating its potential bioactivity. The structural analysis performed with FTIR and GC-MS revealed important functional groups and bioactive compounds that could play a role in these effects&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">293</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Nithya Venugopal&lt;sup&gt;1*&lt;/sup&gt;, Radhika Jayaraman&lt;sup&gt;4&lt;/sup&gt;, Mohammed Junaid Hussain Dowlath&lt;sup&gt;1&lt;/sup&gt;, Ganesh Munuswamy Ramanujam&lt;sup&gt;2&lt;/sup&gt;, Sundarapandian Subramaniyan&lt;sup&gt;1&lt;/sup&gt;, Pratheepa Sivasankari Natarajan&lt;sup&gt;1&lt;/sup&gt;, Jayashri Seetharaman&lt;sup&gt;3&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Anatomy, SRM Medical College Hospital and Research Centre, Faculty of Medicine and Health Sciences, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur, 603203, Kanchipuram, Chennai, Tamil Nadu, India.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Interdisciplinary Institute of Indian System of Medicine, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur, 603203, Kanchipuram, Chennai, Tamil Nadu, India.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biotechnology, Faculty of Science and Humanities, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur, 603203, Kanchipuram, Chennai, Tamil Nadu, India.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Anatomy, Vels Medical College and Hospital, Manjankaranai Village, Tiruvallur District -601102, Tamil Nadu, India.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sundarapandian Subramanian</style></author><author><style face="normal" font="default" size="100%">Mohammed Junaid Hussain Dowlath</style></author><author><style face="normal" font="default" size="100%">Sathish Kumar Karuppannan</style></author><author><style face="normal" font="default" size="100%">Saravanan M</style></author><author><style face="normal" font="default" size="100%">Kantha Devi Arunachalam</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of Solvent on the Phytochemical Extraction and GC-MS Analysis of Gymnema sylvestre</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Chromatography</style></keyword><keyword><style  face="normal" font="default" size="100%">Cold maceration</style></keyword><keyword><style  face="normal" font="default" size="100%">Gymnema sylvestre</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plants</style></keyword><keyword><style  face="normal" font="default" size="100%">plant constituents</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">749-761</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The medicinal plant &lt;em&gt;Gymnema sylvestre&lt;/em&gt; found in the Indian subcontinent and Srilanka is known for its anti-diabetic, diuretic, anti-obesity, anti-cancer, antimicrobial, anti-inflammatory properties. The current study is focused on the phyto compound extraction efficiency of different solvents like ethanol, methanol, ethyl acetate, hexane, benzene and chloroform by gas chromatography–mass spectrometry analysis of &lt;em&gt;Gymenma sylvestre. &lt;/em&gt;From the results, it is concluded that &lt;em&gt;G. sylvestre&lt;/em&gt; leaves extracts contains more than 38 phyto compounds with natural antioxidants potential. Further analysis of the extract will help in identifying the effective compounds which can be of potent use in the pharmacological field.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">749</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sundarapandian Subramanian&lt;sup&gt;1&lt;/sup&gt;, Mohammed Junaid Hussain Dowlath&lt;sup&gt;1&lt;/sup&gt;, Sathish Kumar Karuppannan&lt;sup&gt;1&lt;/sup&gt;, Saravanan M&lt;sup&gt;2&lt;/sup&gt;, Kantha Devi Arunachalam&lt;sup&gt;1,&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Center for Environmental Nuclear Research, Directorate of Research, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mohammed Junaid Hussain Dowlath</style></author><author><style face="normal" font="default" size="100%">Sathish Kumar Karuppannan</style></author><author><style face="normal" font="default" size="100%">Darul Raiyaan GI</style></author><author><style face="normal" font="default" size="100%">Mohamed Khalith SB</style></author><author><style face="normal" font="default" size="100%">Sundarapandian Subramanian</style></author><author><style face="normal" font="default" size="100%">Kantha Deivi Arunachalam</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of Solvents on Phytochemical Composition and Antioxidant Activity of Cardiospermum halicacabum (L.) Extracts</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Cardiospermum halicacabum</style></keyword><keyword><style  face="normal" font="default" size="100%">Cold maceration</style></keyword><keyword><style  face="normal" font="default" size="100%">DPPH</style></keyword><keyword><style  face="normal" font="default" size="100%">GC-MS</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemicals</style></keyword><keyword><style  face="normal" font="default" size="100%">Radical scavenging activity</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1241-1251</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; &lt;em&gt;Cardiospermum halicacabum&lt;/em&gt; (&lt;em&gt;C. halicacabum&lt;/em&gt;) is a common medicinal herb found in India and other Asian countries. It has various medicinal properties such as antimicrobial, pain relief, antibiotics, anti-inflammatory, antioxidants, anticancer etc. It is commonly used for treating diabetes, arthritis, limbs stiffness, rheumatism, lumbago, earache, fever. Type of solvent and polarity intensively affects the antioxidant activity of the extracts due to the solubility of the phytocompounds such as polyphenols and flavonoids in various solvents.&lt;strong&gt; Materials and Methods: &lt;/strong&gt;In this study, different solvents like, ethanol, methanol, chloroform and petroleum ether were used for the extraction of &lt;em&gt;C. halicacabum&lt;/em&gt;. Cold maceration method was followed for extraction. The crude extracts were screened preliminary and then confirmed using Fourier transform-infrared spectroscopy analysis. Gas chromatography-mass spectrometry was used to determine the chemical composition of each extract. The DPPH (2,2-diphenyl- 1-picrylhydrazyl) method was used for the evaluation of the antioxidant activity of different crude extracts of &lt;em&gt;C. halicacabum.&lt;/em&gt; &lt;strong&gt;Results:&lt;/strong&gt; The results showed that there is significant influence of solvent type in preserving various phytocompounds of the &lt;em&gt;C. halicacabum&lt;/em&gt; leaves extract. The evaluation of the antioxidant capacity of different crude extracts was in the order of ethanol &amp;gt; methanol &amp;gt; petroleum ether &amp;gt; chloroform extract.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1241</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Mohammed Junaid Hussain Dowlath, Sathish Kumar Karuppannan, Darul Raiyaan GI, Mohamed Khalith SB, Sundarapandian Subramanian and Kantha Deivi Arunachalam*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Center for Environmental Nuclear Research, Directorate of Research, SRM Institute of Science and Technology, Kattankulathur- 603203, India.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sathish Kumar Karuppannan</style></author><author><style face="normal" font="default" size="100%">Mohammed Junaid Hussain Dowlath</style></author><author><style face="normal" font="default" size="100%">Mohamed Khalith SB</style></author><author><style face="normal" font="default" size="100%">Darul Raiyaan GI</style></author><author><style face="normal" font="default" size="100%">Sundarapandian Subramanian</style></author><author><style face="normal" font="default" size="100%">Kantha Deivi Arunachalam</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phytochemical and Antibacterial Activity of Cardiospermum halicacabum Against Wound Pathogens</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Cardiospermum halicacabum</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemicals</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1303-1310</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Plants serve as an important source for curing various medical ailments for a wide variety of human and animal diseases. It is therefore necessary to prove the biological activities of the selected plants scientifically using modern technology. The current study focuses on the use of &lt;em&gt;Cardiospermum halicacabum &lt;/em&gt;in their wound healing applications. &lt;em&gt;Cardiospermum halicacabum&lt;/em&gt; is a well-known plant that has antibacterial, anti-inflammatory, anti-rheumatic properties and it is also used to treat joint pains, muscle tears, back pain, etc. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; In this study methanolic extracts of the active compounds from &lt;em&gt;Cardiospermum halicacabum &lt;/em&gt;were tested for its phytochemical attributes by qualitative method, GC-MS, and the antioxidant properties were also assessed. The bactericidal activity and Minimal Inhibitory concentration (MIC) of the plant extract has been evaluated in both Gram +ve and Gram -ve microorganisms using the disc diffusion method. &lt;strong&gt;Results:&lt;/strong&gt; The results obtained showed the presence of significant antibacterial and antioxidant activity. The plant extract was found to be more active against Gram positive microbes compared to Gram negative microbes. The extract has the radical scavenging activity of about 77%. And the GCMS results showed the presence of different phytocompounds which are greatly known for their pharmacognistic activities.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1303</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sathish Kumar Karuppannan, Mohammed Junaid Hussain Dowlath, Mohamed Khalith S B, Darul Raiyaan G I, Sundarapandian Subramanian, Kantha Deivi Arunachalam* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Center for Environmental Nuclear Research, Directorate of Research, SRM Institute of Science and Technology, Kattankulathur-603203, India.&lt;/p&gt;
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