<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">S Lalitha</style></author><author><style face="normal" font="default" size="100%">D Anusha</style></author><author><style face="normal" font="default" size="100%">Yogeshkumar Murkunde</style></author><author><style face="normal" font="default" size="100%">Viji Devanand</style></author><author><style face="normal" font="default" size="100%">K Maheshkumar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-Cancer Activity of Cayratia Auriculata Ethanolic Extracts Against Cancer Cell Line A549  An In Vitro Analysis</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Activity against cancer</style></keyword><keyword><style  face="normal" font="default" size="100%">Cell line cancer</style></keyword><keyword><style  face="normal" font="default" size="100%">Ethanol Extract</style></keyword><keyword><style  face="normal" font="default" size="100%">MTT Assay</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">495-499</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;The purpose of this study was to evaluate the anticancer activity of ethanolic &lt;em&gt;cayratia auriculata&lt;/em&gt; extracts using the A549 cell line MTT assay. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Using Soxhlet apparatus, ethanolic extracts from &lt;em&gt;cayratia auriculata &lt;/em&gt;were prepared. The cancer cells were exposed to 12.5, 25, 50 , 100 , 150, 200 μg / mL and incubated for 24 h at different concentrations. Compared with control, &lt;em&gt;C. auriculata&lt;/em&gt; exhibited a cytotoxic effect. &lt;strong&gt;Results: &lt;/strong&gt;At 150 and 200μg / ml concentrations, with 61 percent and 73.7 percent respectively, the highest cytotoxicity was identified. The findings show that cytotoxicity is directly proportionate to the concentration of the extract. IC50 of the ethanolic extract value of &lt;em&gt;C. auriculata&lt;/em&gt; was found to be 102.9μg / ml against the A549 cell line. &lt;strong&gt;Conclusion:&lt;/strong&gt; In the present analysis, &lt;em&gt;C.auriculata &lt;/em&gt;ethanolic extract was shown to be a strong suppressant for cell division and proliferation. As for anti-tumor medicine, it can be a new source and can be effectively used as an immunological anti-malignant compound.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">495</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;S. Lalitha&lt;sup&gt;1&lt;/sup&gt;, D. Anusha&lt;sup&gt;2,&lt;/sup&gt;*, Yogeshkumar Murkunde&lt;sup&gt;3&lt;/sup&gt;, Viji Devanand&lt;sup&gt;4&lt;/sup&gt;, K.Maheshkumar&lt;sup&gt;5&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Demonstrator, Department of Physiology, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra Institute of Higher Education and Research centre (SRIHER), Porur, Chennai -600116, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Professor, Department of Pharmacology, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra Institute of Higher Education and Research centre (SRIHER), Porur, Chennai -600116, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Test Head Animal House/Facility Management (CEFT), Sri Ramachandra Medical College and Research Institute, Sri Ramachandra Institute of Higher Education and Research centre (SRIHER), Porur, Chennai -600116, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;HOD &amp;amp; Professor, Department of Physiology, Stanley Medical College&amp;amp; Hospital, Royapuram, Chennai -600001, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Assistant Medical officer/Lecture Grade II, Department of Biochemistry and Physiology, Government Yoga and Naturopathy Medical college and Hospital, Chennai -600106, INDIA.&lt;/p&gt;
</style></auth-address></record></records></xml>