<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Julio Luis Díaz-Uribe</style></author><author><style face="normal" font="default" size="100%">María Elena Salazar-Salvatierra</style></author><author><style face="normal" font="default" size="100%">Julio Reynaldo Ruiz-Quiroz</style></author><author><style face="normal" font="default" size="100%">Oscar Herrera- Calderon</style></author><author><style face="normal" font="default" size="100%">Eddie Loyola-Gonzales</style></author><author><style face="normal" font="default" size="100%">Freddy Emilio Tataje-Napuri</style></author><author><style face="normal" font="default" size="100%">José Francisco Kong-Chirinos</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phytochemical Profile, Antioxidant and Antibacterial Activity of the Essential Oil of Luma Chequen (Molina) A. Gray from Peru</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial.</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Aromatic plant</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oil</style></keyword><keyword><style  face="normal" font="default" size="100%">Luma chequeen</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plant</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">777-780</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background&lt;/strong&gt;: Luma chequen belongs to Myrtaceae family and it is known as “arrayan”. In the traditional medicine from Peru, L chequen is used as aromatic plant, anti-inflammatory and hypocholesterolemic. Objective: To determine the phytochemical profile, evaluate the antioxidant and the antibacterial activity of &lt;em&gt;L. chequen&lt;/em&gt; essential oil. &lt;strong&gt;Material and Methods&lt;/strong&gt;: In the analysis of the volatile components a Gas Chromatography coupled to Mass Spectrometry (GC-MS) was used to identify the content of terpenes and sesquiterpenes. 2,2-diphenyl-1-picrylhydrazyl (DPPH) was the method used to determine the antioxidant activity and obtain the half inhibitory concentration (IC&lt;sub&gt;50&lt;/sub&gt;). For the antibacterial activity, a colorimetric macrodilution method was carried out to evaluate the effect of the essential oil of &lt;em&gt;L. chequen&lt;/em&gt; against &lt;em&gt;Staphylococcus aureus&lt;/em&gt; ATCC 25923 and Escherichia coli ATCC 25922. &lt;strong&gt;Results:&lt;/strong&gt; The analysis by GC-MS showed two major components alpha-pinene (62.89%) followed by 1,8-cineole (11.94%), and propanoic acid, 2-methyl-, 2-methylpropyl ester with 8.67%. In the antioxidant activity against DPPH radical, the essential oil of &lt;em&gt;L. chequen&lt;/em&gt; showed an IC&lt;sub&gt;50&lt;/sub&gt; equivalent to124.60 ± 2.0 μg/mL. In the antibacterial activity, &lt;em&gt;L. chequen&lt;/em&gt; had an MIC (minimum inhibitory concentration) for &lt;em&gt;Staphylococcus aureus &lt;/em&gt;ATCC 25923 and Escherichia coli ATCC 25922 of 4.35 ± 0 μg/mL and 8.71 ± 0 μg/mL respectively. &lt;strong&gt;Conclusion&lt;/strong&gt;: &lt;em&gt;L. chequen &lt;/em&gt;presented monoterpene compounds as main phytoconstituents as well as antioxidant and antibacterial activity in vitro. The essential oil might be used as antimicrobial agent in the future overall against S. aureus.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">777</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Julio Luis Díaz-Uribe&lt;sup&gt;1&lt;/sup&gt;, María Elena Salazar-Salvatierra&lt;sup&gt;2&lt;/sup&gt;, Julio Reynaldo Ruiz-Quiroz&lt;sup&gt;2&lt;/sup&gt;, Oscar Herrera-Calderon&lt;sup&gt;3,*&lt;/sup&gt;, Eddie Loyola- Gonzales&lt;sup&gt;4&lt;/sup&gt;, Freddy Emilio Tataje- Napuri&lt;sup&gt;5&lt;/sup&gt;, José Francisco Kong- Chirinos&lt;sup&gt;6&lt;/sup&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Basic and Applied Chemistry Department, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, Lima 15001, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Institute for Research in Biological Chemistry, Microbiology and Biotechnology “Marco Antonio Garrido Malo”, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, Lima 15001, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacology, Bromatology and Toxicology, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, Lima, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Pharmaceutical Science, Faculty of Pharmacy and Biochemistry, Universidad Nacional San Luis Gonzaga, Ica 11001, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Departamento de Ciencias Comunitarias, Facultad de Odontología, Universidad Nacional San Luis Gonzaga, Ica 11001, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Surgical Clinical Sciences, Faculty of Human Medicine, Universidad Nacional San Luis Gonzaga, Ica 11001, PERU.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Oscar Herrera-Calderon</style></author><author><style face="normal" font="default" size="100%">Renan Dilton Hañari-Quispe</style></author><author><style face="normal" font="default" size="100%">Johnny Aldo Tinco-Jayo</style></author><author><style face="normal" font="default" size="100%">Josefa Bertha Pari-Olarte</style></author><author><style face="normal" font="default" size="100%">Luz Josefina Chacaltana-Ramos</style></author><author><style face="normal" font="default" size="100%">Eddie Loyola-Gonzales</style></author><author><style face="normal" font="default" size="100%">Melva Iparraguirre-Meza</style></author><author><style face="normal" font="default" size="100%">Mildred Hilda Cóndor- Privat</style></author><author><style face="normal" font="default" size="100%">Beatriz Lilian Galdos-Vadillo</style></author><author><style face="normal" font="default" size="100%">Jenny Mendoza-Vilcahuaman</style></author><author><style face="normal" font="default" size="100%">Rossibel Juana Muñoz-de-la-Torre</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pasuchaca (Geranium ruizii Hieron.): A Medicinal Plant of the Geraniaceae Family with Hypoglycemic Effect on Alloxan-Induced Hyperglycemia in Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antidiabetic drugs</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidants</style></keyword><keyword><style  face="normal" font="default" size="100%">Geranium ruizii</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal therapy</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Pasuchaca</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">315-321</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The current study aims to evaluate the hypoglycemic effect of the hydroalcoholic extract of &lt;em&gt;Geranium ruizii &lt;/em&gt;on alloxan-induced hyperglycemia in albino mice. &lt;strong&gt;Material and Methods: &lt;/strong&gt;&lt;em&gt;Geranium ruizii&lt;/em&gt; was collected in Huancayo, Junin, Peru. A phytochemical analysis was carried out to confirm the chemical groups. In the pharmacological study, hyperglycemia was induced with alloxan at doses of 170 mg/kg in male albino mice, animals with blood sugar levels above 250 mg/dL were included in the protocol. Mice were randomized into five groups (I: Alloxan 170 mg/Kg; II, III and IV (&lt;em&gt;Geranium ruizii &lt;/em&gt;extract: 50; 150 and 300 mg/Kg body weight); and V: glibenclamide, 5mg/Kg B.W. Results: Phytochemical analysis confirmed the presence of tannins, flavonoids, alkaloids, terpenes, saponins and phenolic compounds. It is observed that at doses of 50, 150 and 300 mg/kg reduced blood glucose at 14 days of treatment. &lt;strong&gt;Conclusion: &lt;/strong&gt;The hypoglycemic effect of the hydroalcoholic extract of &lt;em&gt;Geranium ruizii&lt;/em&gt;, administered orally in mice with alloxan-induced hyperglycemia was effective with 150 mg/Kg body weight.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">315</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Oscar Herrera-Calderon&lt;sup&gt;1,*&lt;/sup&gt;, Renan Dilton Hañari-Quispe&lt;sup&gt;2&lt;/sup&gt;, Johnny Aldo Tinco-Jayo&lt;sup&gt;3&lt;/sup&gt;, Josefa Bertha Pari- Olarte&lt;sup&gt;4&lt;/sup&gt;, Luz Josefina Chacaltana-Ramos&lt;sup&gt;4&lt;/sup&gt;, Eddie Loyola-Gonzales&lt;sup&gt;5&lt;/sup&gt;, Melva Iparraguirre-Meza&lt;sup&gt;6&lt;/sup&gt;, Mildred Hilda Cóndor-Privat&lt;sup&gt;6&lt;/sup&gt;, Beatriz Lilian Galdos-Vadillo&lt;sup&gt;6&lt;/sup&gt;, Jenny Mendoza- Vilcahuaman&lt;sup&gt;7&lt;/sup&gt;, Rossibel Juana Muñozde-la-Torre&lt;sup&gt;7&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, Bromatology and Toxicology, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Clinical Pathology Laboratory, Faculty of Veterinary Medicine and Zootechnics, Universidad Nacional del Altiplano, Puno, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Human Medicine, Faculty of Health Sciences, Universidad Nacional de San Cristóbal de Huamanga, Ayacucho, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biochemistry, Universidad Nacional San Luis Gonzaga, Ica, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Pharmaceutical Sciences, Faculty of Pharmacy and Biochemistry, Universidad Nacional San Luis Gonzaga, Ica, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Professional school of obstetrics, Faculty of health sciences, Universidad Peruana Los Andes, Huancayo, Junin, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Academic Department of obstetrics, Faculty of Health Sciences, Universidad Nacional de Huancavelica, Huancavelica, PERU.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Jorge Alejandro Arroyo-Sandoval</style></author><author><style face="normal" font="default" size="100%">Manuel Jesús Marin-Bravo</style></author><author><style face="normal" font="default" size="100%">Jorge Luis Arroyo-Acevedo</style></author><author><style face="normal" font="default" size="100%">Hugo Jesús Justil-Guerrero</style></author><author><style face="normal" font="default" size="100%">Roberto Jesús Chávez-Asmat</style></author><author><style face="normal" font="default" size="100%">Josefa Bertha Pari-Olarte</style></author><author><style face="normal" font="default" size="100%">Javier Hernán Chávez-Espinoza</style></author><author><style face="normal" font="default" size="100%">Jaime David Torres-Lévano</style></author><author><style face="normal" font="default" size="100%">Eddie Loyola-Gonzales</style></author><author><style face="normal" font="default" size="100%">José Santiago Almeida-Galindo</style></author><author><style face="normal" font="default" size="100%">Oscar Herrera-Calderon</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pharmacobotany, Phytochemical Analysis and Anti-inflammatory effect of the Ethanolic Extract of Luffa operculata</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory.</style></keyword><keyword><style  face="normal" font="default" size="100%">Luffa operculata</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacobotany</style></keyword><keyword><style  face="normal" font="default" size="100%">Saponins</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">622-628</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;em&gt; &lt;/em&gt;&lt;/strong&gt;&lt;em&gt;Luffa operculata&lt;/em&gt; is a vegetable species well known in the traditional peruvian medicine for its many medicinal properties and cosmetic applications.&lt;strong&gt; Objective: &lt;/strong&gt;The aim objective was to determine the pharmacognostic characteristics of&lt;em&gt; L. operculata&lt;/em&gt; as well as observing the pharmacological effect of the ethanol extract of &lt;em&gt;L. operculata&lt;/em&gt; fruit on chronic inflammation in rats. &lt;strong&gt;Materials and Method&lt;/strong&gt;: Phytochemical analysis was carried out by using specific chemical reagents for each constituent chemical, the pharmacobotanical study was done with a histological tinction (fruit, steam and leaves), which were stained with Safranin 1% and Toluidine blue 1%; the chronical inflammation was assessed by air bag method in Holztman male rats. Doses of 100, 250 and 500 mg/Kg were tested in order to determine the anti-inflammatory effect, which was demonstrated with histopathological evaluation and lymphocytes reduction. &lt;strong&gt;Results: &lt;/strong&gt;The main findings indicate that the ethanolic extract presented saponins, alkaloids, carbohydrates, terpenes and steroids. The efficiency of lymphocyte reduction per field in the histopathological study of the granuloma was 58.4% with the middle dose of 250 mg/kg (p &amp;lt; 0.0001), which gives a dose-independent anti-inflammatory effect in rats.&lt;strong&gt; Conclusion: &lt;/strong&gt;&lt;em&gt;Luffa operculata &lt;/em&gt;presented anti-inflammatory effect at 250 mg/Kg by oral administration in a chronical experimental model of inflammation in rats.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><accession-num><style face="normal" font="default" size="100%">20</style></accession-num><section><style face="normal" font="default" size="100%">622</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Jorge Alejandro Arroyo-Sandoval&lt;sup&gt;1&lt;/sup&gt;, Manuel Jesús Marin-Bravo&lt;sup&gt;2&lt;/sup&gt;, Jorge Luis Arroyo-Acevedo&lt;sup&gt;3&lt;/sup&gt;, Hugo Jesús Justil-Guerrero&lt;sup&gt;3&lt;/sup&gt;, Roberto Jesús Chávez- Asmat&lt;sup&gt;4&lt;/sup&gt;, Josefa Bertha Pari-Olarte&lt;sup&gt;5&lt;/sup&gt;, Javier Hernán Chávez-Espinoza&lt;sup&gt;5&lt;/sup&gt;, Jaime David Torres-Lévano&lt;sup&gt;6&lt;/sup&gt;, Eddie Loyola- Gonzales&lt;sup&gt;6&lt;/sup&gt;, José Santiago Almeida- Galindo&lt;sup&gt;7&lt;/sup&gt;, Oscar Herrera-Calderon&lt;sup&gt;8,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Chemistry and Chemical Engineering. Universidad Nacional Mayor de San Marcos, Lima, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of Plant Anatomy and Pharmacognosy. Faculty of Biology. Universidad Nacional Mayor de San Marcos, Lima, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Laboratory of Pharmacology, Faculty of Medicine, Universidad Nacional Mayor de San Marcos, Lima, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Section of Neurosurgery, Hospital São Vicente de Paulo. São Paulo, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biochemistry, Universidad Nacional San Luis Gonzaga, Ica, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Pharmaceutical Sciences, Faculty of Pharmacy and Biochemistry, Universidad Nacional San Luis Gonzaga, Ica, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Department of Basic Sciences, Faculty of Human Medicine, Universidad Nacional San Luis Gonzaga, Ica, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;8&lt;/sup&gt;Departament of Pharmacology, Bromatology and Toxicology, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, Lima 15001, PERU.&lt;/p&gt;
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