<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Candra Irawan</style></author><author><style face="normal" font="default" size="100%">Imalia Dwi Putri</style></author><author><style face="normal" font="default" size="100%">Maman Sukiman</style></author><author><style face="normal" font="default" size="100%">Andita Utami</style></author><author><style face="normal" font="default" size="100%">Ismail</style></author><author><style face="normal" font="default" size="100%">Ratna Komala Putri</style></author><author><style face="normal" font="default" size="100%">Anisa Lisandi</style></author><author><style face="normal" font="default" size="100%">Andrean Nur Pratama</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant Activity of DPPH, CUPRAC, and FRAP Methods, as well as Activity of Alpha-Glucosidase Inhibiting Enzymes from Tinospora crispa (L.) Stem Ultrasonic Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Tinospora crispa (L.)</style></keyword><keyword><style  face="normal" font="default" size="100%">Ultrasound-assisted extraction.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">511-520</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Aims: &lt;/strong&gt;The goal of this work was to get the stem extract of &lt;em&gt;Tinospora crispa&lt;/em&gt; (&lt;em&gt;L&lt;/em&gt;.) using ultrasoundassisted extraction (UAE) with duration and amplitude changes to achieve optimal extraction conditions. The antioxidant potential of the extract as measured by 2,2-diphenyl-1-picrylhydrazyl (DPPH), CUPRAC (Cupric Ion Reducing Antioxidant Capacity), FRAP (Ferric Reducing Ability of Plasma), and its antidiabetic potential. &lt;strong&gt;Results: &lt;/strong&gt;The third test of antioxidant methods showed that the measurement of antioxidant activity with, DPPH, CUPRAC, and FRAP gave significantly different results, but CUPRAC and FRAP gave the same response to the ethanol extract of &lt;em&gt;Tinospora crispa&lt;/em&gt; stems, it can be concluded that the extract of &lt;em&gt;Tinospora crispa&lt;/em&gt; stems in all treatments had strong antioxidant activity using either the CUPRAC or methods FRAP. In addition, it is very active as an antidiabetic by inhibiting alpha glucosidase. The optimum extract selected was extract B (extraction time was 35 minutes and amplitude 65%) with IC&lt;sub&gt;50&lt;/sub&gt; values for antioxidant activity in the CUPRAC method of 72.53 ± 0.18 mg/L and the FRAP method of 152.29 ± 2.16 mg/L, while the inhibition of alpha glucosidase was 0.30 ± 0.006 mg/L.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">511</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Candra Irawan&lt;sup&gt;1&lt;/sup&gt;, Imalia Dwi Putri&lt;sup&gt;1&lt;/sup&gt;, Maman Sukiman&lt;sup&gt;2&lt;/sup&gt;, Andita Utami&lt;sup&gt;3&lt;/sup&gt;, Ismail&lt;sup&gt;3,*&lt;/sup&gt;, Ratna Komala Putri&lt;sup&gt;3&lt;/sup&gt;, Anisa Lisandi&lt;sup&gt;3&lt;/sup&gt;, Andrean Nur Pratama&lt;sup&gt;4&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Food Nanotechnology, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Industrial Waste Treatment, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Chemical Analysis, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Research and Development Planning Agency, Tanggamus District, Lampung, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Candra Irawan</style></author><author><style face="normal" font="default" size="100%">Maman Sukiman</style></author><author><style face="normal" font="default" size="100%">Ismail</style></author><author><style face="normal" font="default" size="100%">Imalia Dwi Putri</style></author><author><style face="normal" font="default" size="100%">Andita Utami</style></author><author><style face="normal" font="default" size="100%">Andrean Nur Pratama</style></author><author><style face="normal" font="default" size="100%">M. Ilham Kumala Zalni</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant Capacity and Potential as an Alpha-Glucosidase Inhibitor in Phaleria macrocarpa (Scheff.) Boerl Fruit Peel Ultrasonic Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alpha-glucosidase</style></keyword><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Phaleria macrocarpa (Scheff.) Boerl</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">305-312</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;em&gt;Phaleria macrocarpa &lt;/em&gt;(Scheff.) Boerl is native to the tropical region of Papua Island, Indonesia, and has traditionally been used as a herbal drink, either alone or in combination with other medicinal plants, to treat diseases such as cancer, hypertension, and diabetes mellitus. This study aimed to obtain the fruit peel extract of &lt;em&gt;Phaleria macrocarpa&lt;/em&gt; (Scheff.) Boerl. through the application of ultrasound-assisted extraction (UAE) with variations in time and amplitude to produce optimal extraction conditions. The potential of the extract as an antioxidant using the cupric ion reducing antioxidant capacity (CUPRAC) and ferric reducing antioxidant power (FRAP) methods, and its potential as an antidiabetic through alpha glucosidase inhibition. The optimum extract selected was extract C (extraction time was 45 minutes and amplitude 60%) with IC&lt;sub&gt;50&lt;/sub&gt; values for antioxidant activity in the CUPRAC method of 39.63 ± 0.009 mg/L and the FRAP method of 77.37 ± 0.8 mg/L, while the inhibition of alpha glucosidase was 0.45 ± 0.007 mg/L. It can be concluded that the ethanol extract of &lt;em&gt;Phaleria macrocarpa &lt;/em&gt;fruit peel has the potential as a source of antioxidants and anti-diabetic.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><accession-num><style face="normal" font="default" size="100%">08</style></accession-num><section><style face="normal" font="default" size="100%">305</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Candra Irawan&lt;sup&gt;1&lt;/sup&gt;, Maman Sukiman&lt;sup&gt;2,*&lt;/sup&gt;, Ismail&lt;sup&gt;3&lt;/sup&gt;, Imalia Dwi Putri&lt;sup&gt;1&lt;/sup&gt;, Andita Utami&lt;sup&gt;3&lt;/sup&gt;, Andrean Nur Pratama&lt;sup&gt;4&lt;/sup&gt;, M. Ilham Kumala Zalni&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Food Nanotechnology, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Industrial Waste Treatment, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Chemical Analysis, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;4&lt;/sup&gt;Research and Development Planning Agency, Tanggamus District, Lampung, INDONESIA.&lt;/p&gt;
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