<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Panneerselvam Punniyakotti</style></author><author><style face="normal" font="default" size="100%">Rengasamy Lakshminarayanan Rengarajan</style></author><author><style face="normal" font="default" size="100%">Shanmugam Velayuthaprabhu</style></author><author><style face="normal" font="default" size="100%">Kalaiyarasan Vijayakumar</style></author><author><style face="normal" font="default" size="100%">Ramasamy Manikandan</style></author><author><style face="normal" font="default" size="100%">Arumugam Vijaya Anand</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Protective Effect of Terminalia catappa Leaves and Terminalia chebula Fruits on the Enzymatic and Non-enzymatic Anti-oxidant Levels in the Doxorubicin Induced Toxicity Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Doxorubicin</style></keyword><keyword><style  face="normal" font="default" size="100%">Enzymatic antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Non-enzymatic antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Oxidative stress</style></keyword><keyword><style  face="normal" font="default" size="100%">Termianlia catappa</style></keyword><keyword><style  face="normal" font="default" size="100%">Terminalia chebulla.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">346-349</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Oxidative stress plays an important role in chronic complications of diabetes, cancer, liver disorder etc. The free radicals such as superoxide anions, hydrogen peroxides are causing the oxidative stress and it involves the cellular damage. Evidences recommended that the natural medicines from plant sources are treated to overcome the oxidative stress complications. &lt;strong&gt;Objective:&lt;/strong&gt; The aim of the present is to find the antioxidant activity of the ethanolic extract of&lt;em&gt; Terminalia catappa&lt;/em&gt; leaves and &lt;em&gt;Terminalia chebula&lt;/em&gt; fruits in the doxorubicin (DOX) induced toxicity rats. &lt;strong&gt;Methods:&lt;/strong&gt; Oxidative stress is induced with a single dose of doxorubicin and then the animals were treated with a dose of various concentration of ethanolic extract of&lt;em&gt; T. catappa&lt;/em&gt; leaves and &lt;em&gt;T. chebula&lt;/em&gt; fruits (200, 300 mg/kg/b.w) for 21 days. After the treatment, lipid peroxide (LPO), reduced glutathione (GSH), vitamin C, vitamin E, glutathiones- transferase (GST), glutathione peroxidase (GPx), superoxide dismutase (SOD), catalase levels are determined. Propranolol 25mg/kg is used as standard drug.&lt;strong&gt; Results:&lt;/strong&gt; In the present study, after the treatment of doxorubicin the levels of SOD, CAT, GSH, GST, GPX, vitamin C, vitamin E levels are decreased and LPO level is increased. After the treatment of &lt;em&gt;T. catappa&lt;/em&gt; leaves and &lt;em&gt;T. chebula&lt;/em&gt; fruits the levels were returned to the normal level. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results proved that the ethanolic extract of&lt;em&gt; T. catappa&lt;/em&gt; leaves and &lt;em&gt;T. chebula&lt;/em&gt; fruits may protects the cells from oxidative stress induced by the doxorubicin induced toxicity rats.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">346</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Panneerselvam Punniyakotti&lt;sup&gt;1&lt;/sup&gt;, Rengasamy Lakshminarayanan Rengarajan&lt;sup&gt;2&lt;/sup&gt;, Shanmugam Velayuthaprabhu&lt;sup&gt;3&lt;/sup&gt;, Kalaiyarasan Vijayakumar&lt;sup&gt;4&lt;/sup&gt;, Ramasamy Manikandan&lt;sup&gt;5&lt;/sup&gt;, Arumugam Vijaya Anand&lt;sup&gt;6,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biochemistry, Manonmaniam Sundaranar University, Abishekapatti, Tirunelveli-627 012, Tamilnadu, INDIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Animal Science, Bharathidasan University, Trichy, Tamilnadu, INDIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biotechnology, Bharathiar University, Coimbatore- 641 046, Tamilnadu, INDIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;4&lt;/sup&gt;Assistant Professor, Department of Biochemistry, Sri Meenakshi Vidiyal College of Arts and Science, Trichy, Tamilnadu, INDIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Biochemistry, MIET Arts and Science College, Trichy, Tamilnadu, INDIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore-641 046, Tamilnadu, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ramasamy Manikandan</style></author><author><style face="normal" font="default" size="100%">Arumugam Vijaya Anand</style></author><author><style face="normal" font="default" size="100%">Sampath Kumar</style></author><author><style face="normal" font="default" size="100%">Pushpa</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phytochemical and In vitro Antidiabetic Activity of Psidium Guajava Leaves</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alpha amylase</style></keyword><keyword><style  face="normal" font="default" size="100%">Alpha glucosidase</style></keyword><keyword><style  face="normal" font="default" size="100%">P. guajava</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June/2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">392-394</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The present investigation includes the preliminary screening of phytochemicals and evaluation of &lt;em&gt;in vitro&lt;/em&gt; antidiabetic activity of &lt;em&gt;Psidium guajava&lt;/em&gt; leaves extracts. &lt;strong&gt;Materials&lt;/strong&gt; &lt;strong&gt;and Methods:&lt;/strong&gt; Plant material was subjected to the extraction preparation by soxhlet apparatus by using various solvents such as aqueous, ethanol, chloroform, petroleum ether and hexane. The various kinds of phytochemicals were detected and then &lt;em&gt;in vitro&lt;/em&gt; antidiabetic activity of &lt;em&gt;P. guajava &lt;/em&gt;were detected by using alpha amylase and alpha glucosidase enzyme in an &lt;em&gt;in vitro&lt;/em&gt; model. &lt;strong&gt;Results:&lt;/strong&gt; The study reveals the presence of phytochemicals such as carbohydrate, tannin, flavonoids, phenols etc., Among the various extracts the aqueous and ethanolic extracts which contains the large number of phytoconstituents. The &lt;em&gt;P. guajava &lt;/em&gt;leaves has been successfully inhibited both the enzymes in an &lt;em&gt;in vitro&lt;/em&gt; model. The aqueous extracts of &lt;em&gt;P. guajava&lt;/em&gt; leaves inhibited the alpha amylase and alpha glucosidase enzymes as 72.1% and 74.8% respectively. The ethanolic extract of &lt;em&gt;P. guajava &lt;/em&gt;leaves inhibited the alpha amylase and alpha glucosidase enzymes as 97.5% and 91.8% respectively. &lt;strong&gt;Conclusion:&lt;/strong&gt; From the results obtained in the current studies, the &lt;em&gt;P. guajava &lt;/em&gt;leaves have a prominent antidiabetic property in an &lt;em&gt;in vitro&lt;/em&gt; model and further studies can be carried out in an &lt;em&gt;in vivo&lt;/em&gt; model and the isolation of activie compound from&lt;em&gt; P. guajava &lt;/em&gt;leaves extract is needed&lt;em&gt;.&lt;/em&gt;&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">392</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ramasamy Manikandan&lt;sup&gt;1&lt;/sup&gt;, Arumugam Vijaya Anand&lt;sup&gt;2&lt;/sup&gt;, Sampath Kumar&lt;sup&gt;3&lt;/sup&gt; and Pushpa&lt;sup&gt;4 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of BioChemistry, M.I.E.T Arts and Science College, Trichirappalli-620 007, Tamil Nadu, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore-641 046, Tamil Nadu, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Chemistry and Biosciences, SASTRA University, Kumbakonam&amp;ndash;612 001, Tamil Nadu, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Microbiology, Cauvery College for Women, Tiruchirappalli&amp;ndash;620 018, Tamil Nadu, INDIA.&lt;/p&gt;
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