<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Shabina Komath Chenoly</style></author><author><style face="normal" font="default" size="100%">Vinodini NA</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Abelmoschus esculentus Ameliorates Stress-Induced Cognitive Dysfunction via Antioxidant and Neuroprotective Mechanisms in Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Abelmoschus esculentus</style></keyword><keyword><style  face="normal" font="default" size="100%">Acetylcholine esterase</style></keyword><keyword><style  face="normal" font="default" size="100%">chronic stress</style></keyword><keyword><style  face="normal" font="default" size="100%">Malondialdehyde</style></keyword><keyword><style  face="normal" font="default" size="100%">Morris water maze</style></keyword><keyword><style  face="normal" font="default" size="100%">Superoxide dismutase</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">302-309</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The objective of this study was to determine if there were any effect of Abelmoschus esculentus on chronic stress induced memory loss. &lt;strong&gt;Methods: &lt;/strong&gt;The Swiss Albino Mice (n=30) were divided into five groups, namely control, chronic stress (90 days), chronic stress and ethanolic extract of Abelmoschus esculentus(200mg/kg body weight), and Chronic stress followed by diazepam (2mg/kg body weight), Chronic stress followed by diazepam (2mg/kg body weight) and ethanolic extract of abelmoschus esculentus (200mg/kg body weight). At the end of the experimental period (90 days), animal blood was collected retro-orbitally to analyze the cortisol, Brain tissue was homogenized, and antioxidants and Acetylcholine esterase level was estimated. &lt;strong&gt;Results: &lt;/strong&gt;The Results of the data indicated that administering stress for a duration of 90 days led to a noticeable decline in spatial learning abilities in mice. Our findings indicate that combination of Abelmoschus esculentus and diazepam showed there was an significant improvement in retaining memory. &lt;strong&gt;Conclusion: &lt;/strong&gt;Study indicated that Abelmoschus esculentus shows promise as a viable treatment option for conditions of stress related memory impairment.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">302</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Shabina Komath Chenoly&lt;sup&gt;1&lt;/sup&gt;, Vinodini NA&lt;sup&gt;2*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Associate Professor, Department of Physiology, Vydehi Institute of Medical Sciences &amp;amp; Research Center EPIP area, Bangalore, 5600066, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Associate Professor, Department Of Physiology, Kasturba Medical college Mangalore, Manipal Academy of Higher Education, Manipal, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ajay Pal</style></author><author><style face="normal" font="default" size="100%">Kandikattu Hemanth Kumar</style></author><author><style face="normal" font="default" size="100%">Bharat Bhushan</style></author><author><style face="normal" font="default" size="100%">Vinod Saharan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Ashwagandha Root Extract Inhibits Acetylcholine Esterase, Protein Modification and Ameliorates H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt;-Induced Oxidative Stress in Rat Lymphocytes</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acetylcholine esterase</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidants</style></keyword><keyword><style  face="normal" font="default" size="100%">Ashwagandha</style></keyword><keyword><style  face="normal" font="default" size="100%">DNA damage</style></keyword><keyword><style  face="normal" font="default" size="100%">Protein carbonylation</style></keyword><keyword><style  face="normal" font="default" size="100%">Rat lymphocytes</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2017 </style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">/files/PJ-9-3/10.5530pj.2017.3.52</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">302-309</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Herbs have long been the basis of medical treatment but the practice of herbalism is not strictly based on evidences gathered using scientific methods. Ashwagandha (&lt;em&gt;Withania somnifera L&lt;/em&gt;.) is a traditional medicinal herb used in the treatment of various ailments. &lt;strong&gt;Objective:&lt;/strong&gt; In current study we have evaluated the acetylcholine esterase (AChE) inhibitory and antioxidant potential of Ashwagandha root extract (ARE) in in-vitro and &lt;em&gt;ex-vivo&lt;/em&gt; models to give a scientific base to its use in herbal medicine. &lt;strong&gt;Methodology:&lt;/strong&gt; Simplest extraction e.g. maceration method was performed for preparation of extracts using methanol as solvent. Both &lt;em&gt;in vitro&lt;/em&gt; and &lt;em&gt;in vivo&lt;/em&gt; experimental trial were executed to evaluate the efficacy of root extract. &lt;strong&gt;Result and Discussion:&lt;/strong&gt; ARE substantially scavenged free radicals and effectively prevented protein degradation as well as modification as studied by SDS-PAGE and Western blotting. Pre-treatment with ARE protected rat lymphocytes against H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt;-induced oxidative damage. H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt; treatment resulted in DNA fragmentation and significantly decreased the activities of key antioxidant enzymes namely superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, glucose-6-phosphate dehydrogenase while decreased and increased the content of glutathione and malondialdehyde, respectively. ARE pre-treatment almost reversed these changes indicating its efficiency to suppress hydrogen peroxide-induced oxidative stress. &lt;strong&gt;Conclusion:&lt;/strong&gt; The study provides the scientific basis of pleiotropic functions of Ashwagandha.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">302</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ajay Pal&lt;sup&gt;1&lt;/sup&gt;, Kandikattu Hemanth Kumar&lt;sup&gt;2&lt;/sup&gt;, Bharat Bhushan&lt;sup&gt;*1&lt;/sup&gt; and Vinod Saharan&lt;sup&gt;3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Chemistry and Biochemistry, Chaudhary Charan Singh Haryana Agricultural University, Hisar, Haryana, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Biochemistry and Nanosciences Discipline, Defence Food Research Laboratory, Mysore, Karnataka, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Molecular Biology and Biotechnology, Maharana Pratap University of Agriculture and Technology, Udaipur, Rajasthan, INDIA.&lt;/p&gt;</style></auth-address></record></records></xml>