<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Deepa Shukla</style></author><author><style face="normal" font="default" size="100%">Sajal Srivastava</style></author><author><style face="normal" font="default" size="100%">Talha Jawaid</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Learning and Memory Enhancing Activity of Polyherbal Formulation on Streptozotocin Induced Memory Impairment in Rats via Reducing Mitochondria–Targeted Cytochrome</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alpinia galanga</style></keyword><keyword><style  face="normal" font="default" size="100%">Convolvulus pluricaulis</style></keyword><keyword><style  face="normal" font="default" size="100%">Elevated Plus Maze</style></keyword><keyword><style  face="normal" font="default" size="100%">Glycerrhiza glabra</style></keyword><keyword><style  face="normal" font="default" size="100%">Pole climbing test</style></keyword><keyword><style  face="normal" font="default" size="100%">Social recognition test</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">230-240</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Neurodegenerative diseases and/or brain injury may occur due to mild to severe memory disorders in which Alzheimer's disease (AD) is defined as degradation of neurons and there is no effective therapy or cure for the disease. The intention behind this study was to determine memory enhancing effect of an Ayurvedic polyherbal formulation (PHF) in Streptozotocin-induced memory deficit experimental animal models. &lt;strong&gt;Methods:&lt;/strong&gt; Polyherbal formulation (PHF) was a suspension of three plant extracts i.e. &lt;em&gt;Alpinia galanga, Glycerrhiza glabra &lt;/em&gt;and&lt;em&gt; Convolvulus pluricaulis&lt;/em&gt; along with other excipients. Different behavioral animal models like Social recognition test (SRT), Morris water maze (MWM) test, Pole climbing test (PCT) and Elevated plus maze (EPM) test were used to evaluate efficacy of Polyherbal formulation (PHF) in learning and memory process of animals. Gene expression was performed by RT-PCR and western blot. &lt;strong&gt;Results:&lt;/strong&gt; Results indicated that time of social recognition during trial 2 (SIT2) was reduced significantly (P&amp;lt;0.01) due to PHF administration. In MWM test, treatment with PHF significantly (P&amp;lt;0.01) reduced [F (4, 20) = 6.9] latency to reach hidden platform from session 3. Similarly, PHF was also found effective in pole climbing test and EPM test. RT-PCR results showed p53 regulates the Bcl-2 family proteins its expression in the given experiment was appreciably reduced in PHF (200mg/kg). NR1, NR2B and GAP-43 proteins leads to reduction of brain cell damage. &lt;strong&gt;Conclusion: &lt;/strong&gt;Thus, PHF may be an effective formulation for learning and memory process against STZ-induced memory impairment.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">230</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Deepa Shukla&lt;sup&gt;1,2&lt;/sup&gt;, Sajal Srivastava&lt;sup&gt;2,&lt;/sup&gt;*, Talha Jawaid&lt;sup&gt;3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Pharmacy, Sharda University, Greater Noida, Uttar Pradesh, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Amity Institute of Pharmacy, Amity University Uttar Pradesh, Lucknow Campus, Lucknow 226010, Uttar Pradesh, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacology, College of Medicine, Al Imam Mohammad Ibn Saud Islamic University, P.O. Box 11623, Riyadh 11544, SAUDI ARABIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Jai Prabhu</style></author><author><style face="normal" font="default" size="100%">K Prabhu</style></author><author><style face="normal" font="default" size="100%">Anathbandhu Chaudhuri</style></author><author><style face="normal" font="default" size="100%">Mudiganti Ram Krishna Rao</style></author><author><style face="normal" font="default" size="100%">VS Kalai Selvi</style></author><author><style face="normal" font="default" size="100%">TK Balaji</style></author><author><style face="normal" font="default" size="100%">Sruthi Dinakar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Neuro-protective Effect of Ayurveda Formulation, Saraswatharishtam, on Scopolamine Induced Memory Impairment in Animal Model</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Ayurvedic medicine</style></keyword><keyword><style  face="normal" font="default" size="100%">Elevated Plus Maze</style></keyword><keyword><style  face="normal" font="default" size="100%">Neuroprotection</style></keyword><keyword><style  face="normal" font="default" size="100%">Piracetam</style></keyword><keyword><style  face="normal" font="default" size="100%">Saraswatharishtam</style></keyword><keyword><style  face="normal" font="default" size="100%">Scopolamine</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February  2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">6-13</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;In the management of neurodegenerative and neuropsychiatric diseases, memory loss remains very challenging. Saraswatharishtam (SWRT) is an ayurvedic formulation prescribed for several neurological illnesses like acute anxiety, partial memory loss, slurred speech, neuro degenerative diseases like Parkinson’s, Alzheimer’s etc. &lt;strong&gt;Methods:&lt;/strong&gt; Present study explores the possibilities of curative effects of SWRT on Scopolamine induced memory impairment and to compare the effects of commonly used drug piracetam. Adult Wistar Swiss albino mice were used for this experiment and divided into five different groups for the treatments of the drugs in various combinations. The first group was vehicle treated control while the second group was treated with scopolamine to induce memory impairment. The third group of animals were treated with Scopolamine where the mice were pretreated with standard neuroprotective drug Piracetam, while the fourth and fifth group of animals were treated with scopolamine and the animals were pretreated with SWRT at the doses of 200 and 400 mg/kg respectively to compare with the effect of Piracetam. Scopolamine was administered on day eight, only for 45 minutes in all the cases (Group I- Group V). Several neurobehavioral parameters were examined to confirm the neuroprotective effects of SWRT. &lt;strong&gt;Results: &lt;/strong&gt;Saraswatharishtam significantly reversed the memory loss in mice model revealed from elevated plus maze, radial maze and rectangular maze experiments justifying its neuroprotective potential as observed in usually used synthetic Piracetam. SWRT was found to be nontoxic and very promising antioxidant recorded from acute and chronic toxicological studies. &lt;strong&gt;Conclusions: &lt;/strong&gt;It is suggested that SWRT, could be used as safe and easily available Ayurveda medicine to treat neurological dysfunctions without any side effects. Further translational research is needed to explore its neuro-protective potential.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">6</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Jai Prabhu&lt;sup&gt;1&lt;/sup&gt;, K Prabhu&lt;sup&gt;2&lt;/sup&gt;, Anathbandhu Chaudhuri&lt;sup&gt;3&lt;/sup&gt;, Mudiganti Ram Krishna Rao&lt;sup&gt;4,&lt;/sup&gt;*, VS Kalai Selvi&lt;sup&gt;5&lt;/sup&gt;, TK Balaji&lt;sup&gt;6&lt;/sup&gt;, Sruthi Dinakar&lt;sup&gt;7&lt;/sup&gt;&lt;/strong&gt;&lt;strong&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Research Scholar, Sree Balaji Medical College and Hospital, Chennai, Tamil nadu, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Associate Professor, Department of Anatomy, Sree Balaji Medical College and Hospital, Chennai, Tamil nadu, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Assistant Professor, Department of Biological Sciences, University of Alabama, Tuscaloosa, Alabama, 35401, USA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Professor, Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai, Tamil nadu, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Professor, Department of Biochemistry, Sree Balaji Medical College and Hospital, Chennai, Tamil nadu, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Professor, Department of Anatomy, Chettinad Health City, Chennai 603103, Tamil nadu, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Ayurvedic Physician, Kottakkal Arya Vaidhya Sala, Chennai, Tamil nadu, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Jai Prabhu</style></author><author><style face="normal" font="default" size="100%">K Prabhu</style></author><author><style face="normal" font="default" size="100%">Anathbandhu Chaudhuri</style></author><author><style face="normal" font="default" size="100%">Mudiganti Ram Krishna Rao</style></author><author><style face="normal" font="default" size="100%">V S Kalai Selvi</style></author><author><style face="normal" font="default" size="100%">T K Balaji</style></author><author><style face="normal" font="default" size="100%">Shruthi Dinakar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Neuro-protective Effect of Ayurveda Formulation, Saraswatharishtam, on Scopolamine Induced Memory Impairment in Animal Model</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Ayurvedic</style></keyword><keyword><style  face="normal" font="default" size="100%">Elevated Plus Maze</style></keyword><keyword><style  face="normal" font="default" size="100%">Neuro-protection</style></keyword><keyword><style  face="normal" font="default" size="100%">Piracetam</style></keyword><keyword><style  face="normal" font="default" size="100%">Saraswatharishtam</style></keyword><keyword><style  face="normal" font="default" size="100%">Scopolamine</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">465-472</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; In the management of neurodegenerative and neuropsychiatric diseases, memory loss remains very challenging. Saraswatharishtam (SWRT) is an ayurvedic formulation prescribed for several neurological ailments like acute anxiety, partial memory loss, slurred speech, neuro-degenerative diseases like Parkinson’s, Alzheimer’s etc. &lt;strong&gt;Methods:&lt;/strong&gt; Present study explores the possibilities of curative effects of SWRT on Scopolamine induced memory impairment and to compare the effects of commonly used drug Piracetam. Adult Wistar Swiss albino mice were used for this experiment and divided into five different groups for the treatments of the drugs in various combinations. The first group was vehicle treated control while the second group was treated with scopolamine to induce memory impairment. The third groups of animals were treated with Scopolamine where the mice were pretreated with standard neuro-protective drug Piracetam, while the fourth and fifth groups of animals were treated with scopolamine and the animals were pretreated with SWRT at the doses of 200 and 400 mg/kg respectively to compare with the effect of Piracetam. Scopolamine was administered on day eight, only for 45 minutes in all the cases (Group I- Group V). Several neurobehavioral parameters were examined to confirm the neuro-protective effects of SWRT. &lt;strong&gt;Results:&lt;/strong&gt; Saraswatharishtam significantly reversed the memory loss in mice model as revealed from elevated plus maze, radial maze and rectangular maze experiments justifying its neuroprotective potential as observed in usually used synthetic Piracetam. SWRT was found to be nontoxic and very promising antioxidant recorded from acute and chronic toxicological studies. &lt;strong&gt;Conclusions: &lt;/strong&gt;It is suggested that SWRT, could be used as safe and easily available Ayurveda medicine to treat neurological dysfunctions without any side effects. Further translational research is needed to explore its neuro-protective potential.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">465</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Jai Prabhu&lt;sup&gt;1&lt;/sup&gt;, K Prabhu&lt;sup&gt;2&lt;/sup&gt;, Anathbandhu Chaudhuri&lt;sup&gt;3&lt;/sup&gt;, Mudiganti Ram Krishna Rao&lt;sup&gt;4,*&lt;/sup&gt;, VS Kalai Selvi&lt;sup&gt;5&lt;/sup&gt;, TK Balaji&lt;sup&gt;6&lt;/sup&gt;, Sruthi Dinakar&lt;sup&gt;7&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Research Scholar, Sree Balaji Medical College and Hospital, Chennai, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Associate Professor, Department of Anatomy, Sree Balaji Medical College and Hospital, Chennai, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Assistant Professor, Department of Biological Sciences, University of Alabama, Tuscaloosa, Alabama, 35401, USA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Professor, Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Professor, Department of Biochemistry, Sree Balaji Medical College and Hospital, Chennai, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Professor, Department of Anatomy, Chettinad Health City, Chennai 603103, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Ayurvedic Physician, Kottakkal Arya Vaidhya Sala, Chennai, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Abdulrahman Alsayari</style></author><author><style face="normal" font="default" size="100%">Mohammed Ghazwani</style></author><author><style face="normal" font="default" size="100%">Dalia Almaghaslah</style></author><author><style face="normal" font="default" size="100%">Yahya Alhamhoom</style></author><author><style face="normal" font="default" size="100%">Maha Saad</style></author><author><style face="normal" font="default" size="100%">Rawan Ahmed</style></author><author><style face="normal" font="default" size="100%">Wafa Saeed</style></author><author><style face="normal" font="default" size="100%">Wijden Ali</style></author><author><style face="normal" font="default" size="100%">Sadia Batool</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Bombax ceiba: A Potential Anti-Anxiety Drug</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-anxiety</style></keyword><keyword><style  face="normal" font="default" size="100%">Bombax ceiba leaves</style></keyword><keyword><style  face="normal" font="default" size="100%">Diazepam</style></keyword><keyword><style  face="normal" font="default" size="100%">Elevated Plus Maze</style></keyword><keyword><style  face="normal" font="default" size="100%">Ethanol</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/656</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">712-714</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; &lt;em&gt;Bombax ceiba &lt;/em&gt;is a famous plant used extensively in traditional medicine for various diseases. However, data pertaining to its effects at CNS level is limited. &lt;strong&gt;Objective:&lt;/strong&gt; To analyze the anti-anxiety potential of ethanolic extracts of &lt;em&gt;Bombax ceiba&lt;/em&gt; leaves on rats using the elevated plus maze protocol. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Five groups containing six rats each were treated with respective drugs.Control rats were treated with 0.5ml of 10% ethanol i.p. (negative control). Single treatments of diazepam (2mg/kg i.p) were used as a positive control and varied levels of ethanolic extracts of &lt;em&gt;Bombax ceiba&lt;/em&gt; leaves (150 mg/kg, 250 mg/kg, 400 mg/kg, i.p.) were applied to other groups. The index of anxiety was measured by observing the entry and time duration in the open arm of the EPM. &lt;strong&gt;Results:&lt;/strong&gt; Extract at 400 mg/kg significantly increased the time duration and number of entries into the open arm which was statistically significant (p value &amp;lt;0.05) when compared to the control group (ethanol). Diazepam showed the most significant results when compared to other groups (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.0005). Extracts at 150 mg/kg and 250 mg/kg demonstrated negligible results that were statistically insignificant. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results indicate the anti-anxiety potential of &lt;em&gt;Bombax ceiba&lt;/em&gt; leaves at higher concentration. Further studies are required to analyze the implicated phytochemicals and the mechanism at cellular level.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">712</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Abdulrahman Alsayari, Mohammed Ghazwani, Dalia Almaghaslah, Yahya Alhamhoom, Maha Saad, Rawan Ahmed, Wafa Saeed, Wijden Ali, Sadia Batool&lt;sup&gt;*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;College of Pharmacy, King Khalid University, Abha, KINGDOM OF SAUDIA ARABIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Aslam Pathan</style></author><author><style face="normal" font="default" size="100%">Abdulrahman Alshahrani</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Neuroprotective Effects of Valeriana wallichii on Scopolamine Induced Learning and Memory Impairment in Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alzheimer’s disease</style></keyword><keyword><style  face="normal" font="default" size="100%">Elevated Plus Maze</style></keyword><keyword><style  face="normal" font="default" size="100%">Neuroprotective</style></keyword><keyword><style  face="normal" font="default" size="100%">Scopolamine</style></keyword><keyword><style  face="normal" font="default" size="100%">Valeriana wallichii</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">s38-s41</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; Alzheimer&amp;rsquo;s disease (AD) is the most common cause of dementia in worldwide, treatment options is extremely limited and costly. The present study was conducted to investigate and validate the traditional claim of &lt;em&gt;Valeriana wallichii&lt;/em&gt; on scopolamine treated rats as an AD model. &lt;strong&gt;Methods:&lt;/strong&gt; The &lt;em&gt;Valeriana wallichii&lt;/em&gt; rhizome ethanol extract (25 mg/kg/day) was administered daily along with scopolamine for a period of 14 days following which the elevated plus maze test were performed to assess learning and memory. Rats treated with scopolamine or vehicle only were also included in the experiment. &lt;strong&gt;Result:&lt;/strong&gt; The study demonstrate that scopolamine treatment resulted in learning and memory deficits which were partially and significantly ameliorated by the &lt;em&gt;Valeriana wallichii&lt;/em&gt; rhizome ethanol extract.&lt;strong&gt; Conclusion:&lt;/strong&gt; The study demonstrates the ability of the&lt;em&gt; Valeriana wallichii&lt;/em&gt; rhizome ethanol extract to reverse scopolamine-induced learning and memory deficits in rats.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s38</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Aslam Pathan&lt;sup&gt;1,*&lt;/sup&gt;, Abdulrahman Alshahrani&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology and Therapeutics College of Medicine, Shaqra University, Ministry of Higher Education, Shaqra-11961, KINGDOM OF SAUDI ARABIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Internal Medicine (Neurology), College of Medicine, Shaqra University, Ministry of Higher Education, Shaqra-11961, KINGDOM OF SAUDI ARABIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Divneet Kaur</style></author><author><style face="normal" font="default" size="100%">Richa Shri</style></author><author><style face="normal" font="default" size="100%">Anjoo Kamboj</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of Anti-Anxiety Effect of Brassica oleracea L. Extracts in Experimental Animals</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antianxiety</style></keyword><keyword><style  face="normal" font="default" size="100%">Brassica oleracea</style></keyword><keyword><style  face="normal" font="default" size="100%">Elevated Plus Maze</style></keyword><keyword><style  face="normal" font="default" size="100%">Hole Board</style></keyword><keyword><style  face="normal" font="default" size="100%">Mirror Chamber Test</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">/files/pj-9-5/10.5530pj.2017.5.101/index.html</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">638-643</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Oxidative stress in the brain causes nervous system impairment. Hence the use of antioxidants could be an effective approach to prevent disorders such as anxiety. Plants containing phenolic constituents are reported to be potent antioxidants. &lt;em&gt;Brassica oleracea&lt;/em&gt; L. commonly known as broccoli, is rich in phenolics mainly flavonoids and possesses excellent antioxidant property, however its anxiolytic potential has not been investigated. Thus in the present study antianxiety activity of extracts of broccoli was evaluated in experimental animals. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Various pharmacognostic parameters of the plant material were studied following standard procedures. Groups of six mice each were taken as different treatment groups. Control group received vehicle (1% Carboxy Methyl Cellulose), positive control received Diazepam (2mg/kg) as standard drug while test groups received petroleum ether and hydroalcoholic extracts (50, 100 and 200 mg/kg body weight, p.o.). The effects were evaluated on Elevated Plus Maze (EPM), hole board and mirror chamber tests. Statistical analysis was performed using ANOVA, followed by Turkey&amp;rsquo;s post-hoc test. &lt;strong&gt;Results:&lt;/strong&gt; Hydroalcoholic extract shows dose dependent increase in the average time spent and frequency of entries in the open arms of the EPM; decreased latency, increased time spent and frequency of entries in the mirror chamber; increased number of head dips in hole board test as compared to control was observed. These effects were comparable to the effect produced by diazepam. Phytochemical screening of the bioactive extract revealed the presence of alkaloids, phenols, flavonoids and tannins. &lt;strong&gt;Conclusion:&lt;/strong&gt; From our study, it can be concluded that hydroalcoholic extract of &lt;em&gt;Brassica oleracea &lt;/em&gt;at the dose of 200 mg/kg possesses marked anxiolytic activity.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">638</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Divneet Kaur,&lt;sup&gt;1&lt;/sup&gt; Richa Shri,&lt;sup&gt;2&lt;/sup&gt; Anjoo Kamboj&lt;sup&gt;3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;I.K.Gujral Punjab Technical University, Jalandhar, INDIA&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmaceutical Sciences and Drug Research, Patiala, INDIA&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Chandigarh College of Pharmacy, Landran, Mohali, Punjab, INDIA&lt;/p&gt;</style></auth-address></record></records></xml>