<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Carmen R. Silva-Correa</style></author><author><style face="normal" font="default" size="100%">Jorge L. Campos-Reyna</style></author><author><style face="normal" font="default" size="100%">Víctor E. Villarreal-La Torre</style></author><author><style face="normal" font="default" size="100%">Abhel A. Calderón-Peña</style></author><author><style face="normal" font="default" size="100%">William Antonio Sagástegui-Guarniz</style></author><author><style face="normal" font="default" size="100%">Luz M. Guerrero-Espino</style></author><author><style face="normal" font="default" size="100%">Anabel D González-Siccha</style></author><author><style face="normal" font="default" size="100%">Cinthya L. Aspajo-Villalaz</style></author><author><style face="normal" font="default" size="100%">María V. González-Blas</style></author><author><style face="normal" font="default" size="100%">José L. Cruzado-Razco</style></author><author><style face="normal" font="default" size="100%">Julio Hilario-Vargas</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Potential Neuroprotective Activity of Essential Oils in Memory and Learning Impairment</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alzheimer disease</style></keyword><keyword><style  face="normal" font="default" size="100%">Animal model</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oil</style></keyword><keyword><style  face="normal" font="default" size="100%">Learning</style></keyword><keyword><style  face="normal" font="default" size="100%">Memory</style></keyword><keyword><style  face="normal" font="default" size="100%">Neurodegenerative diseases</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1312-1322</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Memory and learning is negatively affected by many factors. Alzheimer's disease is a progressive and irreversible neurological disorder that occurs gradually, a sickness that is increasingly common, and multiple scientific articles suggest that essential oils improve memory and learning and are useful in the treatment of various neurodegenerative diseases, including Alzheimer's disease. This review aims to conduct a critical collection of current information on research into both memory and learning impairment, as well as essential oils that are able to avoid this neurodegenerative disease. Currently, different animal models have been useful for the study of neurodegenerative problems that alter memory and learning, experimental pharmacological, genetic and toxicological models that can simulate specific cognitive deficit syndromes. In addition, research in this review show several essential oil compounds that present positive results in animal studies, but still lack human clinical trials. Therefore, the assessment of the safety and efficacy of these phytochemical compounds in diseases that cause memory impairment and learning, remain a promising area for future research.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Review article</style></work-type><section><style face="normal" font="default" size="100%">1312</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Carmen R. Silva-Correa&lt;sup&gt;1,&lt;/sup&gt;*, Jorge L. Campos-Reyna&lt;sup&gt;2&lt;/sup&gt;, Víctor E. Villarreal-La Torre&lt;sup&gt;1&lt;/sup&gt;, Abhel A. Calderón-Peña&lt;sup&gt;3&lt;/sup&gt;, William Antonio Sagástegui-Guarniz&lt;sup&gt;1&lt;/sup&gt;, Luz M. Guerrero-Espino&lt;sup&gt;2&lt;/sup&gt;, Anabel D. González-Siccha&lt;sup&gt;1&lt;/sup&gt;, Cinthya L. Aspajo-Villalaz&lt;sup&gt;3&lt;/sup&gt;, María V. González-Blas&lt;sup&gt;1&lt;/sup&gt;, José L. Cruzado- Razco&lt;sup&gt;1&lt;/sup&gt;, Julio Hilario-Vargas&lt;sup&gt;2&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Facultad de Medicina, Universidad Nacional de Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Facultad de Ciencias Biológicas, Universidad Nacional de Trujillo, PERÚ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Swaminathan Gomathi</style></author><author><style face="normal" font="default" size="100%">Rajagopal Shanmuga Sundaram</style></author><author><style face="normal" font="default" size="100%">Vellaichamy Muthupandi Annapandian</style></author><author><style face="normal" font="default" size="100%">Manickam Vijayabaskaran</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Neuroprotective Effect of Pedalium murex Linn. Leaf against Lipopolysaccharide Induced Behavioural Disorders in Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Behavioural studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Learning</style></keyword><keyword><style  face="normal" font="default" size="100%">Memory</style></keyword><keyword><style  face="normal" font="default" size="100%">Neuroprotective</style></keyword><keyword><style  face="normal" font="default" size="100%">Oxidative stress</style></keyword><keyword><style  face="normal" font="default" size="100%">Pedalium murex.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2017</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">957-962</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Effective treatment is necessary to minimize the neuronal damage and oxidative stress. Traditional medicines offer potent pharmacological activity with minimal side effects compared to synthetic drugs to treat such chronic disorders. There is no renowned remedy for arrest or rescuing infection or inflammation-induced brain damage. The present study was aimed to evaluate the neuroprotective effect of ethanol extract of &lt;em&gt;Pedalium murex&lt;/em&gt; Linn. (EEPM) leaves against lipopolysaccharide (LPS)-induced endotoxemia. &lt;strong&gt;Methods:&lt;/strong&gt; Neurodegeneration was induced in rats with a single intraperitoneal injection of LPS (1 mg/kg). The induced endotoxemia constantly linked with battery of behavioural tests viz., choice reaction time task (CRT), 8-arm radial maze (RAM) and water maze test (WMT). At the end of the study, rats were sacrificed, brain hippocampal region was removed and biochemical parameters were measured. &lt;strong&gt;Results:&lt;/strong&gt; In WMT swimming length (cm) was increased in LPS-treated rats when compared to control animals, the swimming length (EEPM; 400 mg/kg) was found to be significant; in RAM, different doses of EEPM at 100, 200 and 400 mg/kg decreased the number of errors in entry 4.00&amp;plusmn;0.36, 4.16&amp;plusmn;0.16and 3.33&amp;plusmn;2.79 respectively when compared with control animals (2.66&amp;plusmn; 0.21). EEPM at 400 mg/kg showed significant activity, in CRT apparatus increased incorrect lever pressing was observed in LPS-treated rats when compared to control animals. Incorrect lever pressing was minimized by EEPM at 400 mg/kg (43.5&amp;plusmn;2.40). &lt;strong&gt;Conclusions:&lt;/strong&gt; Our results showed that EEPM is a hopeful aspirant for hindrance of infection and inflammation induced brain damage by LPS.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">957</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Swaminathan Gomathi&lt;sup&gt;1&lt;/sup&gt;, Rajagopal Shanmuga Sundaram&lt;sup&gt;2*&lt;/sup&gt;, Vellaichamy Muthupandi Annapandian&lt;sup&gt;2&lt;/sup&gt;, Manickam Vijayabaskaran&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Chemistry and JKK Nattraja College of Pharmacy, Komarapalayam, Namakkal, Tamil Nadu &amp;ndash; 638183, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacology, Chemistry and JKK Nattraja College of Pharmacy, Komarapalayam, Namakkal, Tamil Nadu &amp;ndash; 638183, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Natesh Prabhu</style></author><author><style face="normal" font="default" size="100%">Sanjay Hadigal</style></author><author><style face="normal" font="default" size="100%">Ullal sheetal D</style></author><author><style face="normal" font="default" size="100%">Sushma DS</style></author><author><style face="normal" font="default" size="100%">Ashok Shenoy K</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of Tribulus Terrestris on Learning And Memory in Wistar Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Hebb William Maze</style></keyword><keyword><style  face="normal" font="default" size="100%">Learning</style></keyword><keyword><style  face="normal" font="default" size="100%">Memory</style></keyword><keyword><style  face="normal" font="default" size="100%">T Maze</style></keyword><keyword><style  face="normal" font="default" size="100%">Tribulus terrestris</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">26th May 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">68-71</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;The present study was designed to evaluate the effect of aqueous extract of fruits of &lt;em&gt;Tribulus terrestri&lt;/em&gt;s on learning and memory in rodents. &lt;strong&gt;Materials and methods:&lt;/strong&gt; Thirty wistar rats were divided in 5 groups of 6 rats each. Baseline values for the time taken to reach reward chamber (TRC) in the Hebb William Maze and transfer latency (TL) in the T-maze were recorded on Day 1. Mean of 5 sessions was calculated for each rat. Group I was normal control, group II piracetam standard, group III, IV and V received &lt;em&gt;Tribulus terrestris&lt;/em&gt; orally at 100mg/kg, 200mg/kg and 400mg/kg respectively for 14 days. At the end of 14 days, each rat was tested for TRC and TL and compared with the control group. &lt;strong&gt;Results:&lt;/strong&gt; Group IV showed a significant decrease in TRC when compared to group I in Hebb William Maze (p&amp;lt;0.0001). Group IV also showed a significant decrease in TL when compared to group I in T-maze (p&amp;lt;0.0001). Group III showed a significant decrease in TL when compared to group I in the T-maze (p=0.035), however there was no decrease in TRC in this group.&lt;strong&gt; Conclusion: &lt;/strong&gt;The aqueous extract of fruits of &lt;em&gt;Tribulus terrestris&lt;/em&gt; showed a dose dependent beneficial effect in learning and memory models in rats, with 200mg/kg being most beneficial.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt; Hebb William Maze, Learning, Memory, T Maze, &lt;em&gt;Tribulus terrestris&lt;/em&gt;&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Natesh Prabhu, Sanjay Hadigal, Ullal Sheetal D&lt;sup&gt;*&lt;/sup&gt;, Sushma DS and Ashok Shenoy K&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacology, Kasturba Medical College, Light House Hill Road, Mangalore-575001, Manipal University, Manipal, Karnataka, India.&lt;/p&gt;</style></auth-address></record></records></xml>