<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ratna Umi Nurlila</style></author><author><style face="normal" font="default" size="100%">Jumarddin La Fua</style></author><author><style face="normal" font="default" size="100%">Toto Surianto S</style></author><author><style face="normal" font="default" size="100%">Titi Purnama</style></author><author><style face="normal" font="default" size="100%">Muh Ikhsan Idrus</style></author><author><style face="normal" font="default" size="100%">Armayani</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Test of Antihyperuricemia Activity of Methanol Extract of Plantain Peel (Musa Paradisiaca Var. Sapientum) Against Caffeine- Induced Mice (Mus Musculus)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-hyperuricemic effect</style></keyword><keyword><style  face="normal" font="default" size="100%">Hyperuricemia</style></keyword><keyword><style  face="normal" font="default" size="100%">Methanol extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Mus musculus</style></keyword><keyword><style  face="normal" font="default" size="100%">Optimal dosage</style></keyword><keyword><style  face="normal" font="default" size="100%">Plantain peel</style></keyword><keyword><style  face="normal" font="default" size="100%">Uric acid levels</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">226-230</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt;&lt;strong&gt; &lt;/strong&gt;Hyperuricemia occurs when serum uric acid levels rise above the normal range, typically exceeding 7.0 mg/dl for adults and 6.0 mg/dl for women. This condition can lead to various health issues, including gout, kidney stones, and renal failure. &lt;strong&gt;Objective: &lt;/strong&gt;This study aims to verify the effectiveness of the methanol extract from plantain peel (Musa paradisiaca var. sapientum) in reducing uric acid levels in mice (Mus musculus) and to establish the optimal dosage for maximum efficacy. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; This analytical experimental research utilized a paired sample T-test Pretest-Posttest design. The mice were divided into five groups: a Negative Control of Na.CMC 0.5%, a Positive Control of allopurinol at 100 mg/kg body weight, and groups receiving plantain peel methanol extract at 100 mg/kg, 200 mg/kg, and 400 mg/kg body weight. Uric acid levels were measured initially, post-caffeine induction on day 7, and post-extract induction on day 14. &lt;strong&gt;Results:&lt;/strong&gt; The study found that plantain peel methanol extract exhibited an anti-hyperuricemic effect in male mice. Among the dosages tested, 400 mg/kg body weight of the plantain peel methanol extract was the most effective in reducing uric acid levels, followed by the 200 mg/kg and 100 mg/kg doses. &lt;strong&gt;Conclusion:&lt;/strong&gt; Plantain peel methanol extract is effective in reducing uric acid levels in male mice, with 400 mg/kg being the most efficacious dosage. This suggests potential for further exploration of plantain peels as a treatment for hyperuricemia.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">226</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ratna Umi Nurlila&lt;sup&gt;1,&lt;/sup&gt;*, Jumarddin La Fua&lt;sup&gt;2&lt;/sup&gt;, Toto Surianto S&lt;sup&gt;3&lt;/sup&gt;, Titi Purnama&lt;sup&gt;4&lt;/sup&gt;, Muh Ikhsan Idrus&lt;sup&gt;5&lt;/sup&gt;, Armayani&lt;sup&gt;6&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;6&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacy, university of mandala waluya kendari, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Tadris Biology, State Islamic Institute of Kendari, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Public Health, Mandala Waluya University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Medical Laboratory Technology, Mandala Waluya University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Nursing, Mandala Waluya University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Environmental Health, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dayanand Dalawai</style></author><author><style face="normal" font="default" size="100%">Hosakatte Niranjana Murthy</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Chemical Profile and Antioxidant Properties of Andrographis producta (C. B. Clarke) Gamble</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">2</style></keyword><keyword><style  face="normal" font="default" size="100%">4-Di-tert-butylphenol</style></keyword><keyword><style  face="normal" font="default" size="100%">Andrographis</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidants</style></keyword><keyword><style  face="normal" font="default" size="100%">GC-MS</style></keyword><keyword><style  face="normal" font="default" size="100%">Methanol extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Salvigenin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">475-485</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Andrographis producta&lt;/em&gt; (Acanthaceae) is endemic to Western Ghats, India, traditionally used by native people for the control of various ailments including intestinal worms, to relieve constipation and also used to eliminate phlegm in women during postpartum.&lt;strong&gt; Objective:&lt;/strong&gt; To investigate the chemical compounds in root, stem and leaves of&lt;em&gt; A. producta&lt;/em&gt; and their antioxidant properties. &lt;strong&gt;Method:&lt;/strong&gt; The phytochemical contents were determined using spectrophotometric methods and chemical profiling of root, stem and leaf extracts was carried out using GC-MS. Further, extracts were investigated for their antioxidant capacities using in vitro DPPH radical scavenging and FRAP assay.&lt;strong&gt; Results: &lt;/strong&gt;The total phenolics (163.61 mg GAE/g), flavonoids (35.11 ± 0.53 mg QE/g) and tannins (84.52 ± 0.07 mg TAE/g) were highest in stem compared to leaf and root. Stem was exerted superior antioxidant capacities in both DPPH (EC&lt;sub&gt;50 &lt;/sub&gt;3.58 mg/ml) and FRAP assays (1.742 ± 0.02 OD at 1mg/ml) and were comparable to standards. GC-MS analysis revealed total 89 chemical compounds including phenolics, flavonoids, terpenoids and organic acids. 2-Methoxy-4-vinylphenol (0.70 %), 2,4-ditert- butylphenol (9.74 %), phytol (10.32 %), 5-hydroxy-7,8-dimethoxyflavone (11.42 %), gammasitosterol (8.32 %), salvigenin (12.09 %), solanesol, (2.92 %), and alpha-terpinene (4.58 %) were important bioactive compounds found in significant amount. &lt;strong&gt;Conclusion: &lt;/strong&gt;The present investigations indicate that various parts of &lt;em&gt;A. producta&lt;/em&gt; can be explored as good source of antioxidants due to the presence of phenolics and flavonoids. The meticulous assessment of bioactive compounds from&lt;em&gt; A. producta&lt;/em&gt; would be great contribution in field of medicine.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">475</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Dayanand Dalawai, Hosakatte Niranjana Murthy*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Botany, Karnatak University Dharwad 580003, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ritesh Kumar Sharma</style></author><author><style face="normal" font="default" size="100%">Anjana Goel</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Identification of Phytoconstituents in Lawsonia inermis Linn. Leaves Extract by GC-MS and their Antibacterial Potential</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">1</style></keyword><keyword><style  face="normal" font="default" size="100%">4 Napthelenedione</style></keyword><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Lawsone</style></keyword><keyword><style  face="normal" font="default" size="100%">Lawsonia inermis Linn</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Methanol extract</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">1101-1108</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Plant extracts contains multiple active constituents which leads to the production of new drugs from plants and chemicals derived from various parts of plants. The objective of present study was to investigate the GC-MS analysis and antibacterial activity of &lt;em&gt;L. inermis&lt;/em&gt; leaves extracts. &lt;strong&gt;Material and Methods:&lt;/strong&gt; Crude methanol extract and its fractions were tested for the presence of active phytochemicals and GC-MS analysis of hexane; ethyl acetate and aqueous methanol fractions was performed. Antimicrobial activity against six bacterial strain&amp;rsquo;s &lt;em&gt;Escherichia coli, Staphylococcus aureus, Bacillus subtelis, Salmonella typhi, Klebsiella&lt;/em&gt; and &lt;em&gt;Pseudomonas aeruginosa&lt;/em&gt; was also tested. &lt;strong&gt;Results:&lt;/strong&gt; Phytochemical screening of extract confirmed the presence of carbohydrates, glycosides, quinones, steroids and phenol. In GC-MS chromatograms, 56, 108 and 19 peaks were obtained and out of these, 13, 17 and 7 compounds were identified in hexane, ethyl acetate and aqueous methanol fractions, respectively. &lt;strong&gt;Conclusion:&lt;/strong&gt; For best of our knowledge in &lt;em&gt;L.&amp;nbsp;inermis&lt;/em&gt; leaves extract, Celidoniol and Vitamin E has not been reported earlier in hexane fractions. While 2, 3 dihydrobenzo furan, 1-H indole -1, 3 (2H)-dione, 1 (3H)-Isobenzofuranone, 1H Isoindole-1, 3 (2H) Dione, Napthelene, 2 ethoxy, 2 (4H) Benzofuranone, Vitamin E, Benzene, 1 isocyano 4 methyl are also identified for the first time in ethyl acetate fraction. Also, in aq. Methanol fraction 1(3H)-isobenzofuranone, Squalene and Vit E were not previously identified. Highest antibacterial activity was confirmed in crude methanol extract which might be due to all the antibacterial compounds present in its fractions. The present study helped in identifying phytoconstituents present in the extract and its fractions which are responsible for various biological and antibacterial activities.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">xx1101</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ritesh Kumar Sharma&lt;sup&gt;1,&lt;/sup&gt;*, Anjana Goel&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Ph.D. Scholar, Department of Biotechnology, IAH, GLA University, Mathura, Uttar Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Associate Professor, Department of Biotechnology, IAH, GLA University, Mathura, Uttar Pradesh, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ravinder Kaur</style></author><author><style face="normal" font="default" size="100%">Sarabjit Kaur</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anxiolytic Potential of Methanol Extract from Ageratum conyzoides Linn Leaves</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ageratum conyzoides</style></keyword><keyword><style  face="normal" font="default" size="100%">Anxiolytic</style></keyword><keyword><style  face="normal" font="default" size="100%">Methanol extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Quercetin</style></keyword><keyword><style  face="normal" font="default" size="100%">TLC.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">29th Apr, 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">236-241</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective: &lt;/strong&gt;&lt;em&gt;Ageratum conyzoides&lt;/em&gt; Linn. (&lt;em&gt;Asteraceae&lt;/em&gt;) has been widely used in African traditional medicine for healing mental and infectious diseases. The present study was designed to scientifically validate the traditional claim of A. conzyoides as anti-anxiety drug and to identify the compound responsible for the anxiolytic effects of A. conzyoides.&lt;strong&gt; Method:&lt;/strong&gt; The methanol extract of A. conzyoides was prepared by soxhlet apparatus. The methanol extract was fractionated into ethylacetate and butanol fractions by liquid-liquid partitioning method. Methanol extract (100 and 200 mg/kg; p.o.) and its prepared fractions (25 and 50 mg/kg; p.o.) were evaluated for anxiolytic activity in mice by using elevated plus maze (EPM) model. Thin layer chromatography studies were performed to identify the possible anxiolytic component. &lt;strong&gt;Results: &lt;/strong&gt;Methanol extract at both doses showed significant, when compared to vehicle control group, increase in time spent and number of entries in open arms of EPM confirming the anti-anxiety effects of A. conzyoides. Liquid-liquid partitioning of methanol extract gave two fractions (ethylacetate and butanol) which were administrated at 25 and 50 mg/kg doses to mice in EPM, respectively. Results showed that ethylacetate fraction was responsible for anxiolytic effects of methanol extract of A. conzyoides. The TLC studies were carried out for ethylacetate fraction and Quercetin was identified by comparing R&lt;sub&gt;f&lt;/sub&gt; values with the standard (Quercetin). &lt;strong&gt;Conclusion: &lt;/strong&gt;The present investigation revealed that the extract has significant anxiolytic effect. The flavonoid quercetin may be responsible for the observed anxiolytic effects of A. conyzoides.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words:&lt;em&gt;&lt;/em&gt;&lt;/strong&gt;&lt;em&gt;Ageratum conyzoides&lt;/em&gt;, Anxiolytic, Methanol extract, Quercetin, TLC.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">236</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ravinder Kaur&lt;sup&gt;1&lt;/sup&gt; and Sarabjit Kaur&lt;sup&gt;1*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmaceutical Sciences, Pharmacognosy and Phytochemistry Laboratory, Guru Nanak Dev University, Amritsar-143005, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ravinder Kaur</style></author><author><style face="normal" font="default" size="100%">Sarabjit Kaur</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anxiolytic Potential of Methanol Extract from Ageratum conyzoides Linn Leaves</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ageratum conyzoides</style></keyword><keyword><style  face="normal" font="default" size="100%">Anxiolytic</style></keyword><keyword><style  face="normal" font="default" size="100%">Methanol extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Quercetin</style></keyword><keyword><style  face="normal" font="default" size="100%">TLC</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Jul-Aug 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">236-241</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Objective:&lt;/strong&gt; Ageratum conyzoides Linn. (Asteraceae) has been widely used in African traditional medicine for healing mental and infectious diseases. The present study was designed to scientifically validate the traditional claim of A. conzyoides as anti-anxiety drug and to identify the compound responsible for the anxiolytic effects of A. conzyoides. &lt;strong&gt;Method:&lt;/strong&gt; The methanol extract of A. conzyoides was prepared by soxhlet apparatus. The methanol extract was fractionated into ethylacetate and butanol fractions by liquid-liquid partitioning method. Methanol extract (100 and 200 mg/kg; p.o.) and its prepared fractions (25 and 50 mg/kg; p.o.) were evaluated for anxiolytic activity in mice by using elevated plus maze (EPM) model. Thin layer chromatography studies were performed to identify the possible anxiolytic component. &lt;strong&gt;Results:&lt;/strong&gt; Methanol extract at both doses showed significant, when compared to vehicle control group, increase in time spent and number of entries in open arms of EPM confirming the anti-anxiety effects of A. conzyoides. Liquid-liquid partitioning of methanol extract gave two fractions (ethylacetate and butanol) which were administrated at 25 and 50 mg/kg doses to mice in EPM, respectively. Results showed that ethylacetate fraction was responsible for anxiolytic effects of methanol extract of A. conzyoides. The TLC studies were carried out for ethylacetate fraction and Quercetin was identified by comparing Rf values with the standard (Quercetin). &lt;strong&gt;Conclusion: &lt;/strong&gt;The present investigation revealed that the extract has significant anxiolytic effect. The flavonoid quercetin may be responsible for the observed anxiolytic effects of A. conyzoides.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">236</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Ravinder Kaur&lt;sup&gt;1&lt;/sup&gt; and Sarabjit Kaur&lt;sup&gt;1*&lt;/sup&gt; &lt;/strong&gt;Department of Pharmaceutical Sciences, Pharmacognosy and Phytochemistry Laboratory, Guru Nanak Dev University, Amritsar-143005, INDIA&lt;/p&gt;</style></auth-address></record></records></xml>