<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Diny Kamilah</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Robiatul Adawiyah</style></author><author><style face="normal" font="default" size="100%">Annysa Ellycornia Silvyana</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Senna Siamea Hexane Extract: Potent Antifungal Activity Against Candida albicans, Candida Krusei and Identification of Its Chemicals Content</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antifungal</style></keyword><keyword><style  face="normal" font="default" size="100%">Chemical content.</style></keyword><keyword><style  face="normal" font="default" size="100%">Hexane extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Senna siamea</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">999-1004</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt;&lt;em&gt; Senna siamea&lt;/em&gt; contains several chemical: flavonoid, steroids, terpenoids, alkaloid, and tanin which is as an antifungal againts of Candida sp because interfere function of the fungal cell membrane and inhibit syntesis of chitin. Candida albicans and Candida krusei could causing oral candidiasis, vulvovaginal infections, life threatening candidiasis, such as candidemia and internal organ infections&lt;em&gt;. S. siamea&lt;/em&gt; is a medicinal plant which empirically used as antifungal. &lt;em&gt;S. siamea &lt;/em&gt;leaves has been reported to exhibit activity against Candida sp but limited to ethanol extract. Thus, the evaluation of other extract- and identification of active compound(s) against&lt;em&gt; C. albicans&lt;/em&gt; and&lt;em&gt; C. krusei &lt;/em&gt;is needed to be explore. &lt;strong&gt;Methods:&lt;/strong&gt; First, the microscopic morphology of&lt;em&gt; S. siamea &lt;/em&gt;leaves were observed using Scanning Electron Microscope. The leaves were then extracted sequentially by hexane, ethyl acetate, and methanol solvent using the ultrasonic assisted extraction method, followed by its&lt;em&gt; in vitro &lt;/em&gt;antifungal activity evaluation. The most active extract was further evaluated for its chemical(s) content by LC MS. &lt;strong&gt;Results:&lt;/strong&gt; Scanning Electron Microscope identified the presence of oxalate in the leaves of&lt;u&gt; S. siamea&lt;/u&gt;. Evaluation of the antifungal activity showed that the hexane extract had highest antifungal compared to others.&lt;strong&gt; Conclusions:&lt;/strong&gt; &lt;em&gt;S. siamea &lt;/em&gt;hexane extract leaf is prospective to be developed as an antifungal. Further in vivo research are needed.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><section><style face="normal" font="default" size="100%">999</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Diny Kamilah&lt;sup&gt;1&lt;/sup&gt;, Berna Elya1, Robiatul Adawiyah&lt;sup&gt;2,*&lt;/sup&gt;, Annysa Ellycornia Silvyana&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, Universitas Indonesia, INDONESIA&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Parasitology Department , Faculty of Medicine, Universitas Indonesia, INDONESIA&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Study Program of Pharmacy, Sekolah Tinggi Ilmu Kesehatan Medistra Indonesia&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Anis Yohana Chaerunisaa</style></author><author><style face="normal" font="default" size="100%">Muhaimin Muhaimin</style></author><author><style face="normal" font="default" size="100%">Syamsurizal Syamsurizal</style></author><author><style face="normal" font="default" size="100%">Harizon Harizon</style></author><author><style face="normal" font="default" size="100%">Tiana Milanda</style></author><author><style face="normal" font="default" size="100%">Imam Adi Wicaksono</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antifungal Activity of Neolignan Derivatives from Eusideroxylon zwageri Against Pathogenic Fungus Microsporum gypseum</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antifungal</style></keyword><keyword><style  face="normal" font="default" size="100%">Eusiderin</style></keyword><keyword><style  face="normal" font="default" size="100%">Eusideroxylon zwageri</style></keyword><keyword><style  face="normal" font="default" size="100%">Microsporum gypseum</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">993-999</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Bulian wood (&lt;em&gt;Eusideroxylon zwageri&lt;/em&gt;) known as iron wood. It was known as wood source which fungi and insect resistant. These effects were interconnected with secondary metabolites contained within. &lt;strong&gt;Methods: &lt;/strong&gt;&lt;em&gt;Eusideroxylon zwageri&lt;/em&gt; wood powder was macerated with methanol and fractinated with n-Hexane, dichloromethane, ethyl acetate. Eusiderin I and Compound B were isolated from n-hexane fraction, while Compound C were isolated from dichloromethane fraction. Eusiderin I, compound A and Compound B were characterized using melting point, UV spectroscopy and compared with previous data. Antifungal activity test was conducted with &lt;em&gt;Microsporum gypseum&lt;/em&gt; using paper disc method. &lt;strong&gt;Results: &lt;/strong&gt;A research on antifungal activity of Neolignan derivatives from &lt;em&gt;Eusideroxylon zwageri &lt;/em&gt;against pathogenic fungus &lt;em&gt;Microsporum gypseum &lt;/em&gt;had been carried out. Eusiderin I, Compound B and Compound C were isolated from wood of &lt;em&gt;Eusideroxylon zwageri&lt;/em&gt;. All three compounds are white crystals with melting point in such 99-100 oC, 110-112 oC, 98-99 oC, respectively and UV spectrum data is similar to reference. The antifungal activity test of Eusiderin I, Compound B and Compound C from Bulian wood (&lt;em&gt;Eusideroxylon zwager&lt;/em&gt;i) to phatogen fungus of &lt;em&gt;Microsporum gypseum &lt;/em&gt;showed that with five different concentrations (5, 25, 50, 100 and 200 ppm), Eusiderin I was a potent antifungal because it had a strong activity in inhibiting the&lt;em&gt; Microsporum gypseum &lt;/em&gt;growth. The 5 days incubation test result showed that 50 ppm Eusiderin I could inhibit the &lt;em&gt;Microsporum gypseum&lt;/em&gt; colony growth. The 100 ppm Eusiderin I gave the most effective inhibition precentage because it could inhibit the &lt;em&gt;Microsporum gypseum &lt;/em&gt;colony growth (= 93.9%). &lt;strong&gt;Conclusion: &lt;/strong&gt;Based on this data, Eusiderin I can be indicated an antifungal candidate.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">993</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Anis Yohana Chaerunisaa&lt;sup&gt;1,&lt;/sup&gt;*, Muhaimin Muhaimin&lt;sup&gt;2,3&lt;/sup&gt;, Syamsurizal Syamsurizal&lt;sup&gt;2,3&lt;/sup&gt;, Harizon Harizon&lt;sup&gt;2&lt;/sup&gt;, Tiana Milanda&lt;sup&gt;4&lt;/sup&gt;, Imam Adi Wicaksono&lt;sup&gt;5 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutic and Pharmaceutical Technology, Faculty of Pharmacy, Padjadjaran University, Jatinangor, 45363, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Chemistry Education, Faculty of Education, University of Jambi, Jambi, 36361, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Chemistry, Faculty of Science and Technology, University of Jambi, Jambi, 36361, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Pharmaceutical Biology, Faculty of Pharmacy, Padjadjaran University, Jatinangor, 45363, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Padjadjaran University, Jatinangor, 45363, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Víctor Eduardo Villarreal-La Torre</style></author><author><style face="normal" font="default" size="100%">William Sagástegui Guarniz</style></author><author><style face="normal" font="default" size="100%">Carmen Silva-Correa</style></author><author><style face="normal" font="default" size="100%">Lizardo Cruzado- Razco</style></author><author><style face="normal" font="default" size="100%">Raúl Siche</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antimicrobial Activity and Chemical Composition of Momordica Charantia: A Review</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial</style></keyword><keyword><style  face="normal" font="default" size="100%">Antifungal</style></keyword><keyword><style  face="normal" font="default" size="100%">Charantin</style></keyword><keyword><style  face="normal" font="default" size="100%">Cucurbitaceae</style></keyword><keyword><style  face="normal" font="default" size="100%">Cucurbitane</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemicals</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February  2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">213-222</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;em&gt;Momordica charantia&lt;/em&gt; L. (bitter melon) is a plant belonging to the Cucurbitaceae family and is widely distributed in tropical and subtropical areas around the world, mainly in Asia, India, China and Brazil, where it is traditionally used as a medicinal plant, and the fruits of some varieties of &lt;em&gt;M. charantia&lt;/em&gt; are consumed as food. Studies have determined that this plant contains a great diversity of bioactive compounds with therapeutic potential like charantin, α-momorcharin and MAP30, and highlighting its properties as antidiabetic, antiulcer, antioxidant, antimicrobial, anthelmintic, antihyperglycemic and anticancer. Review shows the complete botanical description of the plant (fruits, leaves, stem, etc.), the bioactive chemical compounds reported in the plant species, the antimicrobial activity of the extracts or fractions of &lt;em&gt;M. charantia&lt;/em&gt;, emphasizing the antibacterial and antifungal activities, with respective values of MIC (Minimum Inhibitory Concentration) reported according to the methodology used in each study. The review seeks to update the phytochemical and pharmacological knowledge of &lt;em&gt;M. charantia&lt;/em&gt;, which would be useful for researchers in their search for new chemical compounds of the plant, studies of its safety and efficacy, as well as the evaluation of its possible synergistic action in combination with other antimicrobials, in order to find new therapeutic alternatives against bacterial resistance.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Review Article </style></work-type><section><style face="normal" font="default" size="100%">213</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Víctor Eduardo Villarreal-La Torre&lt;sup&gt;1,&lt;/sup&gt;*, William Sagástegui Guarniz&lt;sup&gt;1&lt;/sup&gt;, Carmen Silva-Correa&lt;sup&gt;1&lt;/sup&gt;, Lizardo Cruzado-Razco&lt;sup&gt;1&lt;/sup&gt;, Raúl Siche&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Departamento de Farmacología, Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Facultad de Ciencias Agropecuarias, Universidad Nacional de Trujillo, PERU.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">S. Shanthi</style></author><author><style face="normal" font="default" size="100%">R. Radha</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-microbial and Phytochemical Studies of Mussaenda frondosa Linn. Leaves</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial</style></keyword><keyword><style  face="normal" font="default" size="100%">Antifungal</style></keyword><keyword><style  face="normal" font="default" size="100%">Extract</style></keyword><keyword><style  face="normal" font="default" size="100%">High Performance Thin Layer Chromatography (HPTLC)</style></keyword><keyword><style  face="normal" font="default" size="100%">Mussaenda</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">630-635</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;em&gt;Mussaenda frondosa&lt;/em&gt; L (Rubiaceae) has been traditionally used in the treatment of White leprosy, eye troubles, skin infections, tuberculosis, jaundice, ulcers, wounds, cough and Bronchitis. The current study investigated antimicrobial effects of &lt;em&gt;Mussaenda frondosa &lt;/em&gt;L against bacteria and fungus. In addition, Phytochemical profiling of the methanol extract of &lt;em&gt;Mussaenda frondosa&lt;/em&gt; was done using High Performance Thin Layer Chromatography (HPTLC). The antimicrobial activity of Methanol (MEMF), Ethyl acetate (EEMF), Chloroform (CEMF) and Hexane (HEMF) extracts of &lt;em&gt;Mussaenda frondosa&lt;/em&gt; leaves were tested against nine bacterial and four fungal strains. The Methanol extract showed significant antibacterial and antifungal activity than hexane, Chloroform, Ethyl acetate extracts which could be attributed to the presence of phenols, flavonoids and the other bioactive compounds identified through phytochemical screening. The findings in the present study offer a scientific support to the ethno medicinal use of the plant by the traditional healers.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">630</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;S.Shanthi&lt;sup&gt;1,*&lt;/sup&gt;, R.Radha&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy, Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and research, porur, chennai-600 116, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy, College of Pharmacy, Madras Medical College, Chennai- 600 003,Tamilnadu, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Oscar Herrera-Calderon</style></author><author><style face="normal" font="default" size="100%">Kainat Ejaz</style></author><author><style face="normal" font="default" size="100%">Mahnoor Wajid</style></author><author><style face="normal" font="default" size="100%">Muzzamil Shehzad</style></author><author><style face="normal" font="default" size="100%">Johnny Aldo Tinco-Jayo</style></author><author><style face="normal" font="default" size="100%">Edwin Enciso-Roca</style></author><author><style face="normal" font="default" size="100%">César Franco-Quino</style></author><author><style face="normal" font="default" size="100%">Ricardo Ángel Yuli-Posadas</style></author><author><style face="normal" font="default" size="100%">Victor Chumpitaz-Cerrate</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Azadirachta indica: Antibacterial Activity of Neem Against Different Strains of Bacteria and their Active Constituents as Preventive in Various Diseases</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial</style></keyword><keyword><style  face="normal" font="default" size="100%">Antifungal</style></keyword><keyword><style  face="normal" font="default" size="100%">Azadirachta indica</style></keyword><keyword><style  face="normal" font="default" size="100%">Natural antibiotics</style></keyword><keyword><style  face="normal" font="default" size="100%">Natural products</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1597-1604</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Neem has become valuable plant in the world which shows the solutions for hundreds to thousands problems. &lt;em&gt;Azadirachta indica&lt;/em&gt; (Neem) is a rapidly growing evergreen well known tree found Pada generally in various regions of world like America, Africa and India. It has been widely used in Chinese, Ayurveda and Unani medicines across the world especially in Asians countries for the prevention and treatment of diseases. The different parts of neem plant contain biological compounds responsible for antibacterial, antiviral and antifungal activities. It is considered as safe medicinal plants and modulates the numerous biological processes without any adverse effect. Neem tree produces some active compounds which contain biological activities, parts of neem tree such as Root, bark, leaf, flower, seed and fruit together possesses biological activities. Various compounds have been obtained from various parts of neem. Biological activities of few of them have been studied. Hence, the article is aims to utilize the medicinal properties of whole neem plant in various disorders of mankind.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Review Article </style></work-type><section><style face="normal" font="default" size="100%">1597</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Oscar Herrera-Calderon&lt;sup&gt;1,&lt;/sup&gt;*, Kainat Ejaz&lt;sup&gt;2&lt;/sup&gt;, Mahnoor Wajid&lt;sup&gt;3&lt;/sup&gt;, Muzzamil Shehzad&lt;sup&gt;4&lt;/sup&gt;, Johnny Aldo Tinco- Jayo&lt;sup&gt;5&lt;/sup&gt;, Edwin Enciso-Roca&lt;sup&gt;5&lt;/sup&gt;, Cesar Franco-Quino&lt;sup&gt;6&lt;/sup&gt;, Ricardo Ángel Yuli-Posadas&lt;sup&gt;7&lt;/sup&gt;, Victor Chumpitaz-Cerrate&lt;sup&gt;8&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, Lima, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biochemistry, Sardar Bahadur Khan Women’s University, Balochistan, PAKISTAN.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biotechnology, University of Central Punjab, Lahore, PAKISTAN.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Biotechnology, Faisalabad Institute of Research Science and Technology, Faisalabad, PAKISTAN.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Faculty of Health Sciences, Universidad Nacional de San Cristóbal de Huamanga, Ayacucho, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Universidad Continental, Huancayo, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;8&lt;/sup&gt;Laboratory of Pharmacology, Universidad Científica del Sur, Lima, PERU.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Irani Binti Alloha</style></author><author><style face="normal" font="default" size="100%">Nurul ‘Ain Liyana Binti Aziz</style></author><author><style face="normal" font="default" size="100%">Ghasak Ghazi Faisal</style></author><author><style face="normal" font="default" size="100%">Zurainie Abllah</style></author><author><style face="normal" font="default" size="100%">Mohd Hafiz Arzmi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effects of Eurycoma Longifolia Jack (Tongkat Ali) Alcoholic Root Extract Against Oral Pathogens</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antifungal</style></keyword><keyword><style  face="normal" font="default" size="100%">Candida albicans</style></keyword><keyword><style  face="normal" font="default" size="100%">Eurycoma longifolia Jack</style></keyword><keyword><style  face="normal" font="default" size="100%">Lactobacillus casei.</style></keyword><keyword><style  face="normal" font="default" size="100%">Root extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptococcus mutans</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1299-1302</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Eurycoma longifolia jack (E.L) is a herbal medicinal plant of South-East Asian origin, popularly recognized as ‘Tongkat Ali.’ The plant roots have been scientifically proven to have many biological effects including antibacterial activity however, no previous research to date has studied the effect on oral pathogens including cariogenic bacteria. This study was done to determine the antibacterial and antifungal activities of E.L. root extract against three common oral pathogens. &lt;strong&gt;Material and Methods:&lt;/strong&gt; The microorganisms used were &lt;em&gt;Candida albicans, Streptococcus mutans &lt;/em&gt;and &lt;em&gt;Lactobacillus casei.&lt;/em&gt; E.L root was extracted using soxhlet method. Disc diffusion assay was conducted using extract concentration of 200 mg/ml. Nystatin and Ampicillin were used as positive control for fungal and bacterial tests respectively. Minimum Inhibitory Concentration (MIC) was done to determine the lowest inhibitory concentration of the extract on the microorganisms. &lt;strong&gt;Results: &lt;/strong&gt;E.L extract inhibited the growth of Candida albicans and Streptococcus mutans at a concentration of 200 mg/ ml with a zone of inhibition of 16.0 ± 3.0 mm and 7.0 ± 1.0 mm respectively. There was no antimicrobial effect of the extract on Lactobacillus casei. The MIC of E.L extract against both Candida albicans and Streptococcus mutans was 25 mg/ml. &lt;strong&gt;Conclusions: &lt;/strong&gt;The results from this study revealed the potential use of Eurycoma longifolia jack as an antimicrobial agent which can be used to produce new oral care products.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1299</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Irani Binti Alloha&lt;sup&gt;1&lt;/sup&gt;, Nurul ‘Ain Liyana Binti Aziz&lt;sup&gt;1&lt;/sup&gt;, Ghasak Ghazi Faisal&lt;sup&gt;2&lt;/sup&gt;,*, Zurainie Abllah&lt;sup&gt;3&lt;/sup&gt;, Mohd Hafiz Arzmi&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Students, Kuliyyah of Dentistry, IIUM, MALAYSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Lecturer, Fundamental Dental and Medical Sciences Department Kuliyyah of Dentistry, IIUM, MALAYSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Paediatric Dentistry and dental public health, IIUM, MALAYSIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ali Mohammed Mohammed Ali Al-Samman</style></author><author><style face="normal" font="default" size="100%">Kahkashan</style></author><author><style face="normal" font="default" size="100%">Nadeem Ahmad Siddique</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Gas Chromatography–Mass Spectrometry (GC-MS/MS) Analysis, Ultrasonic Assisted Extraction, Antibacterial and Antifungal Activity of Emblica officinalis Fruit Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial</style></keyword><keyword><style  face="normal" font="default" size="100%">Antifungal</style></keyword><keyword><style  face="normal" font="default" size="100%">Emblica officinalis</style></keyword><keyword><style  face="normal" font="default" size="100%">GC-MS/MS</style></keyword><keyword><style  face="normal" font="default" size="100%">Ultrasonic assisted extraction</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">315-323</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;strong&gt;Introduction&lt;/strong&gt;: &lt;em&gt;Emblica officinalis&lt;/em&gt; is one of the common plants being used traditionally in different ways to search for cures and relief from various diseases. Among these diseases,&lt;em&gt; Emblica officinalis&lt;/em&gt; had many of medicinal uses in treating a wide variety of bacterial and fungal infections. In this study, Ultrasonic assisted extraction (UAE) was efficiently used for the preparation of aqueous and methanolic extracts of &lt;em&gt;Embelica officinalis&lt;/em&gt; fruits (EOFE). The phytoconstituents was detected through GC-MS/MS analysis to confirm antimicrobial effect of EOFE. &lt;strong&gt;Materials and methods&lt;/strong&gt;: The extraction was carried out at 20ºC, for 20 min using a solid-to-solvent ratio of 1: 60 w/v. The extracts were subjected to GC-MS/MS analysis. The &lt;em&gt;in-vitro&lt;/em&gt; effect of extracts against twenty one microbial strains was investigated by an agar well diffusion method in different concentrations (25 μg/mL-1000 μg/mL). &lt;strong&gt;Results&lt;/strong&gt;: The percentage yield was found to be 41.33% w/v and 23.0 % w/v with water and methanol, respectively. Phenol,3,5-bis1,1 dimethylethyl, 2,4-di-tert-butylphenol and heptasiloxa ne1,1,3,3,5,5,7,7,9,9,11,11,13,13-tetradecamethyl were confirmed by GC-MS/MS analysis. Effectiveness of extracts against Gram negative bacteria; &lt;em&gt;Providencia alcalifaciens&lt;/em&gt; and Gram positive bacteria; &lt;em&gt;Bacillus pumilis, Bacillus polymyxa and fungal strains; Neurospora crassa, Aspergillus brasileinsis and Cladosporium oxysporum&lt;/em&gt; are reported for the first time. Aqueous extract revealed excellent antibacterial activity at 50 μg/mL and antifungal activity at 100 μg/mL whereas methanolic extract showed antifungal activity at 250 μg/mL. &lt;strong&gt;Conclusion&lt;/strong&gt;: Results highlight the considerable inhibitory effect of EOFE against various microbial species was mainly due to the presence of phenolic compounds and other phytocompounds.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">315</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Ali Mohammed Mohammed Ali Al-Samman&lt;sup&gt;1&lt;/sup&gt;, Kahkashan&lt;sup&gt;2&lt;/sup&gt;, Nadeem Ahmad Siddique&lt;sup&gt;1,&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Bioactive Natural Compound Laboratory (BNCL); Department of Pharmacognosy and Phytochemistry, Glocal School of Pharmacy, Glocal University, Saharanpur- 247121, Uttar Pradesh, INDIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Computer Science and Bio Informatics, Faculty of Natural Science. Jamia Millia Islamia, New Delhi, Delhi- 110025, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">William Antonio Sagástegui Guarniz</style></author><author><style face="normal" font="default" size="100%">Kirley Marques Canuto</style></author><author><style face="normal" font="default" size="100%">Paulo Riceli Vasconcelos Ribeiro</style></author><author><style face="normal" font="default" size="100%">Hilania Valeria Dodou</style></author><author><style face="normal" font="default" size="100%">Karla Nascimento Magalhaes</style></author><author><style face="normal" font="default" size="100%">KellenMiranda Sá</style></author><author><style face="normal" font="default" size="100%">Patrícia Georgina Garcia do Nascimento</style></author><author><style face="normal" font="default" size="100%">Karine Lima Silva</style></author><author><style face="normal" font="default" size="100%">Gleilton Weyne Passos Sales</style></author><author><style face="normal" font="default" size="100%">Mirian Parente Monteiro</style></author><author><style face="normal" font="default" size="100%">Nadia Accioly Pinto Nogueira</style></author><author><style face="normal" font="default" size="100%">Sikiru Olaitan Balogun</style></author><author><style face="normal" font="default" size="100%">Mary Anne Medeiros Bandeira</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Momordica Charantia L. Variety from Northeastern Brazil: Analysis of Antimicrobial Activity and Phytochemical Components</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial</style></keyword><keyword><style  face="normal" font="default" size="100%">Antifungal</style></keyword><keyword><style  face="normal" font="default" size="100%">Ethnopharmacology</style></keyword><keyword><style  face="normal" font="default" size="100%">in vitro activity</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1312-1324</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;&lt;em&gt;Momordica charanthia &lt;/em&gt;L., Curcubitaceae, is a pantropical food and medicinal plant. The plant is included in the Official List of Brazilian Medicinal Plants of interest to the Brazilian Unified Health System. The study aimed to perfom microbiological studies with extracts of &lt;em&gt;Momordica charanthia&lt;/em&gt; L. including chemical characterization of the active extracts. &lt;strong&gt;Methods:&lt;/strong&gt; The antimicrobial activity was evaluated with the hydroalcoholic and acetone extracts of&lt;em&gt; M. charantia&lt;/em&gt; leaves, fruits and seeds from northeastern Brazil using microdilution broth technique on the selected clinical bacterial and fungal strains. Extracts that presented antimicrobial were subjected to ultra performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QToF-ESI-MS). &lt;strong&gt;Results:&lt;/strong&gt; The&lt;em&gt; in vitro &lt;/em&gt;antimicrobial assays demonstrated that the leaves extracts presented good antibacterial effect against four &lt;em&gt;Staphylococcus aureus &lt;/em&gt;strains, and a weak antifungal activity agaist &lt;em&gt;Candida albicans&lt;/em&gt;. Fourteen compounds were identified in the hydroalcoholic extract, while 12 were found in the acetone extract. The most important compounds were kaempferol, quercertin and triterpenoids like cucurbitacins. &lt;strong&gt;Conclussion: &lt;/strong&gt;The present study demonstrated the potential antibacterial activity of &lt;em&gt;M. charantia&lt;/em&gt; L. from northeastern part of Brazil, in addition to important phytochemical metabolites known to possess antibacterial activities, particularly against microrganisms of clinical importance. The UPLC phytochemical profile of the Brazilian variety is reported here for the first time. The phytochemical profile of the LHE and FAE demonstrated the presence of biologically and pharmacologically active compounds. There is lack of biological and pharmacological studies to support the medicinal uses of this important plant. The Brazilian variety of &lt;em&gt;M. Charantia &lt;/em&gt;could be a potential therapeutic agent in the treatment of infections.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1312</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;William Antonio Sagástegui Guarniz&lt;sup&gt;1,8&lt;/sup&gt;, Kirley Marques Canuto&lt;sup&gt;2&lt;/sup&gt;, Paulo Riceli Vasconcelos Ribeiro&lt;sup&gt;2&lt;/sup&gt;, Hilania Valeria Dodou&lt;sup&gt;1&lt;/sup&gt;, Karla Nascimento Magalhaes&lt;sup&gt;3&lt;/sup&gt;, Kellen Miranda Sá&lt;sup&gt;3&lt;/sup&gt;, Patrícia Georgina Garcia do Nascimento&lt;sup&gt;4&lt;/sup&gt;, Karine Lima Silva&lt;sup&gt;5&lt;/sup&gt;, Gleilton Weyne Passos Sales&lt;sup&gt;6&lt;/sup&gt;, Mirian Parente Monteiro&lt;sup&gt;1&lt;/sup&gt;, Nadia Accioly Pinto Nogueira&lt;sup&gt;1&lt;/sup&gt;, Sikiru Olaitan Balogun&lt;sup&gt;7&lt;/sup&gt;,*, Mary Anne Medeiros Bandeira&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacy, Faculty of Pharmacy, Odontology and Nursing, Universidade Federal do Ceará, Ceará, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Embrapa Agroindústria Tropical, Ceará, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Horto de Plantas Medicinais Prof FJA Matos, Universidade Federal do Ceará, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Chemistry, Faculty of Chemistry, Universidade Federal do Ceará, Ceara, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Medicine, Faculty of Medicine, Universidade Federal do Ceará, Ceará, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Departamento de Análises Clínicas e Toxicológicas, Universidade Federal do Ceará, Ceará, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Faculdade Noroeste do Mato Grosso - AJES, 78.320-000, Juína, Mato Grosso, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;8&lt;/sup&gt;Department of Pharmacology, Faculty of Pharmacy and Biochemistry, National University of Trujillo, PERU.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Bandenawaz Ramadurga</style></author><author><style face="normal" font="default" size="100%">Rakesh Kumar Jat</style></author><author><style face="normal" font="default" size="100%">Shrishailappa Badami</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pharmacognostic Evaluation and Antimicrobial Activity of Root of Careya arborea</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial</style></keyword><keyword><style  face="normal" font="default" size="100%">Antifungal</style></keyword><keyword><style  face="normal" font="default" size="100%">Careya arborea</style></keyword><keyword><style  face="normal" font="default" size="100%">standardization</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">608-612</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; &lt;em&gt;Careya arborea&lt;/em&gt; is known for its traditional medicinal properties and reported for potent antitumor, antioxidant, hepatoprotective and many other activities. Its stem bark, leaves and fruits were studied biologically, but so far its root has not been studied.&lt;strong&gt; Aim: &lt;/strong&gt;The aim of the present study is to standardize the root of &lt;em&gt;Careya arborea &lt;/em&gt;and its extracts pharmacognostically and also to screen its extracts for their antimicrobial activities against several bacteria and fungi using standard procedures.&lt;strong&gt; Materials and Methods:&lt;/strong&gt; Loss on drying, extractive and ash values, fluorescence and phytochemical analysis of the root and its extracts were studied using standard procedures. Antimicrobial activity was carried out by determining minimum inhibitory concentration. &lt;strong&gt;Results:&lt;/strong&gt; Among all the extracts, the successive ethyl acetate extract was found to be the most active with lowest MIC values against &lt;em&gt;L. acidophilius, S. aureus, C. freundii, P. aeruginosa and M. luteus.&lt;/em&gt; The successive chloroform extract was also found to be highly active against &lt;em&gt;P. aeruginosa and fungi, M. furfur and C. albicans&lt;/em&gt;. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results are helpful in standardizing the root of the plant and since several of the root extracts possess antimicrobial properties, there is a need to isolate its constituents.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Short Communication</style></work-type><section><style face="normal" font="default" size="100%">608</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Bandenawaz Ramadurga&lt;sup&gt;1,*&lt;/sup&gt;, Rakesh Kumar Jat&lt;sup&gt;2&lt;/sup&gt;, Shrishailappa Badami&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biological Sciences, Baze University, Abuja, NIGERIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmaceutical Sciences, JJT University, Chudela, Rajasthan, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Radiant Research Laboratories Pvt. Ltd., Bangalore, Karnataka, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Abinash Sahoo</style></author><author><style face="normal" font="default" size="100%">Thankamani Marar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phytochemical Analysis, Antioxidant Assay and Antimicrobial Activity in Leaf Extracts of Cerbera odollam Gaertn</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial</style></keyword><keyword><style  face="normal" font="default" size="100%">Antifungal</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidants</style></keyword><keyword><style  face="normal" font="default" size="100%">Cerbera odollam. G</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemicals</style></keyword><keyword><style  face="normal" font="default" size="100%">Radical scavenging</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/480</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">285-292</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; In the current study, methanol and aqueous extracts of leaf of &lt;em&gt;Cerbera odollam Gaertn&lt;/em&gt; were screened for its antibacterial, antifungal, phytochemicals and antioxidant activities. Phytochemical constituents were investigated both qualitatively and quantitatively. &lt;strong&gt;Methods:&lt;/strong&gt; The leaf extracts of &lt;em&gt;Cerbera odollam Gaertn&lt;/em&gt; were prepared by drying and extracted using Soxhlet apparatus into methanol and aqueous media, which were subjected to phytochemical screening. Total phenols, tannins, flavanols, alkaloids and its antioxidant activity were determined using spectroscopic techniques. Antimicrobial activity were determined using well diffusion method. &lt;strong&gt;Results:&lt;/strong&gt; Aqueous extract exhibits higher content of phenols, tannins, flavanols and alkaloids, whereas methanol extract exhibits higher content of anthocyanin and cardiac glycoside respectively. Aqueous extract exhibits higher inhibitory concentration (IC %) value for DPPH (2, 2-Diphenyl-1-picrylhydrazyl) and H&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;2&lt;/sub&gt; radical scavenging assay and reducing power (RP) assay. The methanol extracts exhibited higher inhibitory concentration (IC %) value in SO and NO radical scavenging assay, exhibiting antioxidant properties in five antioxidant models that were investigated. The methanol extract showed some antibacterial activity against&lt;em&gt; Bacillus subtilis,&lt;/em&gt; &lt;em&gt;Staphylococcus aureus, Salmonella typhi and Escherichia coli &lt;/em&gt;with inhibitory zone ranging from 2 mm to 3 mm, whereas the aqueous extract showed no activity. High antifungal activity was found against &lt;em&gt;Saccharomyces cerevisiae&lt;/em&gt; and &lt;em&gt;Candida albicans&lt;/em&gt; for methanol extract and moderate for aqueous extract with inhibitory zone ranging from 9mm to 26 mm. &lt;strong&gt;Conclusion:&lt;/strong&gt; The finding of our study have suggested that the extracts of &lt;em&gt;Cerbera odollam Gaertn&lt;/em&gt;, possesses a significant amount of phytochemicals and exhibits antioxidant and antifungal activities.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">285</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Abinash Sahoo, Thankamani Marar* &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;School of Biotechnology and Bioinformatics, D.Y.Patil Deemed to be University, Plot no. 50, Sector 15, CBD Belapur, Navi Mumbai, Maharashtra, INDIA.&lt;/p&gt;</style></auth-address></record></records></xml>