<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Candra Irawan</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Muhammad Hanafi</style></author><author><style face="normal" font="default" size="100%">Fadlina Chany Saputri</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Potential of Rhinachanthus nasutus (L.) Kurz Leaves Extract as an Antioxidant and Inhibitor of α-Glucosidase Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-diabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">CUPRAC method</style></keyword><keyword><style  face="normal" font="default" size="100%">RnLK</style></keyword><keyword><style  face="normal" font="default" size="100%">UAE</style></keyword><keyword><style  face="normal" font="default" size="100%">α-glucosidase activity</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">373-378</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Aims:&lt;/strong&gt; The goal of this study is to learn more about the antioxidant and antidiabetic properties of&lt;em&gt; Rhinachantus nasutus &lt;/em&gt;(L.) Kurz (RnLK) leaf extract. The Ultrasound-Assisted Extraction (UAE) technique was used to extract the leaf material, and the solvent used was ethanol with a 70% concentration. The total phenol content (TPC) of the extracted material was determined. The Cupric Ion Reducing Antioxidant Capacity (CUPRAC) method was used to examine antioxidant activity, whereas α-glucosidase activity was used to test antidiabetic action.&lt;strong&gt; Results:&lt;/strong&gt; The ethanol extract of RnLK leaves yielded 8.36%, with a TPC of 607.1±0.2 mg GAE/g sample. The IC&lt;sub&gt;50&lt;/sub&gt; value for leaf extract antioxidant activity was 19.1±0.1 mg/L. Furthermore, the leaf extract inhibits α-glucosidase activity and has an IC&lt;sub&gt;50&lt;/sub&gt; value of 81.3±3 mg/L, making it an antidiabetic. &lt;strong&gt;Conclusion:&lt;/strong&gt; The ethanolic extract of RnLK leaves can be used as an alternative antioxidant and antidiabetic material, according to the findings of this study.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><accession-num><style face="normal" font="default" size="100%">18</style></accession-num><section><style face="normal" font="default" size="100%">373</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Candra Irawan&lt;sup&gt;1,2&lt;/sup&gt;, Berna Elya&lt;sup&gt;1,*&lt;/sup&gt;, Muhammad Hanafi&lt;sup&gt;3&lt;/sup&gt;, Fadlina Chany Saputri&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy Universitas Indonesia, Depok, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Food Nanotechnology, Politeknik AKA Bogor, Bogor, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Research Center for Chemistry, Indonesian Institute of Science, Serpong, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Manish Kumar</style></author><author><style face="normal" font="default" size="100%">Ankita Misra</style></author><author><style face="normal" font="default" size="100%">Akanksha Srivastava</style></author><author><style face="normal" font="default" size="100%">Pushpendra Kumar Shukla</style></author><author><style face="normal" font="default" size="100%">L M Tewari</style></author><author><style face="normal" font="default" size="100%">Sharad Srivastava</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comparative Pharmacognostical and Pharmacological Evaluation of Costus speciosus (Koen) J.E. Sm. Germplasm Collected from Eastern Ghats of India</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-diabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory</style></keyword><keyword><style  face="normal" font="default" size="100%">Costus speciosus</style></keyword><keyword><style  face="normal" font="default" size="100%">Diosgenin</style></keyword><keyword><style  face="normal" font="default" size="100%">HPTLC</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February  2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">150-156</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Costus speciosus &lt;/em&gt;is an erect perennial herb belonging to family Costaceae, an important medicinal plant widely used in several indigenous medicinal formulations. &lt;strong&gt;Objective: &lt;/strong&gt;A comparative evaluation of Pharmacognostical and Pharmacological potential of &lt;em&gt;Costus speciosus &lt;/em&gt;for the validation of traditional claims and quality parameters for industry. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Pharmacognostical studies were performed as per Ayurvedic Pharmacopeia of India and quantification of diosgenin was done through HPTLC. &lt;em&gt;In vitro&lt;/em&gt; antidiabetic activity was evaluated by α-amylase inhibition assay based on starch iodine method and &lt;em&gt;in vitro &lt;/em&gt;anti-inflammatory were done by using inhibition of protein denaturation assay. &lt;strong&gt;Results: &lt;/strong&gt;The pharmacognostical standards were also laid down for each sample. Morpho-anatomical characters had no distinct variation in all the collected samples of Eastern Ghats. The quantification of diosgenin (without hydrolysis of samples) in the collected germplasm varies significantly from 0.002 to 0.076 % on dry weight basis. The maximum content was recorded in NBCS-06 from Patiya, Bhubaneswar and was identified as distinct chemotype with high metabolite content. IC&lt;sub&gt;50&lt;/sub&gt; value of&lt;em&gt; Costus speciosus &lt;/em&gt;extract in starch-iodine assay was found to be maximum in NBCS- 6 (87.54 μg/ml) and inhibition of protein denaturation assay was found to be maximum in NBCS- 11 (73.91 μg/ml), respectively. &lt;strong&gt;Conclusion: &lt;/strong&gt;The study suggests that the &lt;em&gt;Costus speciosus&lt;/em&gt; germplasm possess potential anti-inflammatory and anti-diabetic activity and comparative pharmacognostical parameters will be useful in collection of location specific potential samples for industrial usage along with quality control of raw materials.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">150</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Manish Kumar&lt;sup&gt;1,2&lt;/sup&gt;, Ankita Misra&lt;sup&gt;1&lt;/sup&gt;, Akanksha Srivastava&lt;sup&gt;1&lt;/sup&gt;, Pushpendra Kumar Shukla&lt;sup&gt;1&lt;/sup&gt;, L. M. Tewari&lt;sup&gt;2&lt;/sup&gt;, Sharad Srivastava&lt;sup&gt;1,&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Pharmacognosy Division, CSIR-National Botanical Research Institute, Lucknow (U.P.) 226001, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Botany, D.S.B. Campus, Kumaun University, Nainital-263002, Uttarakhand, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Roopal Mittal</style></author><author><style face="normal" font="default" size="100%">Shailesh Sharma</style></author><author><style face="normal" font="default" size="100%">Amit Mittal</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Critical Review on Ethnobotanical and Pharmacological Aspects of Euryale Ferox Salisb.</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-aging</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-cytotoxic</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-diabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Cerebrosides</style></keyword><keyword><style  face="normal" font="default" size="100%">Ethnobotanical</style></keyword><keyword><style  face="normal" font="default" size="100%">Euryale ferox</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1444-1454</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;One of the relished dry fruits known by the names of Makhana, Phool Makhana, Gorgon Nut and Fox Nut in the Indian continent, Euryale ferox Salisb. (Nymphaeaceae) is the only plant that belongs to Euryale genus. It is found in abundance in Mithila, Darbhanga and Madhubani region of Bihar state. Since ages, in Ayurveda and Chinese practices, it has been used for the treatment of the renal disorder, chronic diarrhoea, excessive leucorrhea and hepatic dysfunctioning. Its bio-active compounds act as antioxidant, antimicrobial, antiischaemic, anti-diabetic, immunomodulatory, anti-melanogenic, anti-cytotoxic. &lt;strong&gt;Methods: &lt;/strong&gt;The information has been collected from various scientific journals, reviews, books, reports and patent databases.&lt;strong&gt; Results:&lt;/strong&gt; This review summarizes the isolated bioactive compounds in different extracts, patented compounds/formulations with pharmacological activities, present in different parts of Euryale ferox Salisb. Hence, it has been used as a remedy for numerous ailments since long and also proves itself as a panacea for humanity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1444</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Roopal Mittal&lt;sup&gt;1,2,3&lt;/sup&gt;,* Shailesh Sharma&lt;sup&gt;3&lt;/sup&gt;, Amit Mittal&lt;sup&gt;4&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Research Scholar, IKG Punjab Technical University, Jalandhar (Punjab) 144601, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacology, R. K. S. D. College of Pharmacy, Kaithal, Haryana-136027, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmaceutical Research, Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy, BELA (Ropar) (Punjab) 140111, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar-Delhi G.T. Road (NH-1), Phagwara (Punjab) 144411, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vigasini Subbiah</style></author><author><style face="normal" font="default" size="100%">Pannaga Nagaraja</style></author><author><style face="normal" font="default" size="100%">Priya Narayan</style></author><author><style face="normal" font="default" size="100%">Holenarasipur GunduRao Nagendra</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of Pharmacological Properties of Caesalpinia bonducella Seed and Shell Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-diabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-mitotic</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-oxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Caesalpinia bonducella</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January-2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">150-154</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Background:&lt;/strong&gt;&lt;em&gt; Caesalpinia bonducella&lt;/em&gt; L. is a medicinal plant belonging to the family Caesalpiniaceae. It is a prickly shrub widely distributed all over the world especially in Indian tropical regions such as Kerala, Andaman and Nicobar Islands and Sri Lanka. There are claims that its leaves or seeds/ seed kernel possess antipyretic, antidiuretic, antibacterial, antiviral, antiestrogenic and antidiabetic activities Due to the above properties several preparations of the plant were used in folk medicine.&lt;strong&gt; Materials and Methods:&lt;/strong&gt; The aqueous extract of &lt;em&gt;Caesalpinia bonducella&lt;/em&gt; nut containing the seed and the shell, has been evaluated for qualitative analysis of secondary metabolites (tannis, flavonoids, alkaloids, saponins, coumarins, quinone and phenols), in-vitro anti -inflammatory, anti-diabetic assay, antioxidant, antimitotic and antimicrobial activity. The studies were carried out using HRBC membrane stabilization, inhibition of alpha amalyse enzyme, DPPH method, green gram growth inhibition, agar diffusion method respectively. &lt;strong&gt;Results:&lt;/strong&gt; Our results indicate the presence of Alkaloids, Flavanoids and Saponins. We report in our study the antidiabetic, anti-inflammatory, anti-oxidant, anti-microbial and antimitotic activity of &lt;em&gt;Caesalpinia bonducella.&lt;/em&gt;&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">150</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Vigasini Subbiah, Pannaga Nagaraja, Priya Narayan&lt;sup&gt;*&lt;/sup&gt;, Holenarasipur GunduRao Nagendra &lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;Department of Biotechnology, Sir M Visvesvaraya Institute of Technology, Hunasamaranahalli, Bangalore- 562 157, Karnataka, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gaurav Sharma</style></author><author><style face="normal" font="default" size="100%">Sunil Kumar</style></author><author><style face="normal" font="default" size="100%">Megha Sharma</style></author><author><style face="normal" font="default" size="100%">Navneet Upadhyay</style></author><author><style face="normal" font="default" size="100%">Sunil Kumar</style></author><author><style face="normal" font="default" size="100%">Zabeer Ahmed</style></author><author><style face="normal" font="default" size="100%">Neeraj Mahindroo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-Diabetic, Anti-Oxidant and Anti-Adipogenic Potential of Quercetin Rich Ethyl Acetate Fraction of Prunus persica</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-adipogenic</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-diabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-oxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Prunus persica</style></keyword><keyword><style  face="normal" font="default" size="100%">Quercetin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/509</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">463-469</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Diabetes mellitus is enfeebling threatening diseases with continuously increasing rates of incidence and mortality and it may rise tremendously by 2025. &lt;strong&gt;Objective:&lt;/strong&gt; Quercetin rich ethyl acetate fraction (PP-EtOA) of leaves of &lt;em&gt;Prunus persica&lt;/em&gt; was evaluated for antidiabetic, anti-oxidant and anti-adipogenic activities. Material and Methods: Streptozotocin (STZ)-induced diabetic rat model, oral glucose tolerance test (OGTT) and normalglycemic rat models were investigated at the doseof 100 and 200 mg/kg,&lt;em&gt;p.o&lt;/em&gt;. of PP-EtOA. &lt;strong&gt;Results:&lt;/strong&gt; At 200 mg/kg, significant anti-hyperglycaemic activity(&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05) was observed in all the rat models. In STZ induced diabetic rat model, improvement in body weight and lipid profile was also observed.DPPH (2,2&amp;rsquo;-diphenyl-1-picrylhydrazyl) free radical scavenging method showed dose dependent scavenging. Preadipocyte differentiation assay (3T3-L1) showed significant inhibition of differentiation. HPLC fingerprinting analysis of fraction was also performed. &lt;strong&gt;Conclusion:&lt;/strong&gt; PP-EtOA possesses potent free radical scavenging property. Its antihyperglycemic and antiadipogenic activities may be due to quercetin (flavonoid) and may prove to be effective in the treatment of diabetes mellitus and diabetes driven dyslipidemic conditions.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">463</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Gaurav Sharma&lt;sup&gt;1*&lt;/sup&gt;, Sunil Kumar&lt;sup&gt;1&lt;/sup&gt;, Megha Sharma&lt;sup&gt;1&lt;/sup&gt;,&amp;nbsp;Navneet Upadhyay&lt;sup&gt;1&lt;/sup&gt;, Sunil Kumar&lt;sup&gt;2&lt;/sup&gt;, Zabeer Ahmed&lt;sup&gt;3&lt;/sup&gt;, Neeraj Mahindroo&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Pharmaceutical Sciences, Shoolini University, Solan, Himachal Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Medical Parasitology, Post Graduate Institute of Medical Education and Research, Chandigarh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Division of Pharmacology, Indian Institute of Integrative Medicine (CSIR), Jammu, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hanafi</style></author><author><style face="normal" font="default" size="100%">Candra Irawan</style></author><author><style face="normal" font="default" size="100%">Henny Rochaeni</style></author><author><style face="normal" font="default" size="100%">Lilis Sulistiawaty</style></author><author><style face="normal" font="default" size="100%">Achmad Nandang Roziafanto</style></author><author><style face="normal" font="default" size="100%">Supriyono</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phytochemical Screening, LC-MS Studies and Antidiabetic Potential of Methanol Extracts of Seed Shells of Archidendron bubalinum (Jack) I.C. Nielson (Julang Jaling) from Lampung, Indonesia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-diabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Archidendron bubalinum</style></keyword><keyword><style  face="normal" font="default" size="100%">Mass spectrometry</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical screening</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">s77-s82</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Some Malaysia and Indonesia people believed that root and seed shell of &lt;em&gt;Archidendron bubalinum&lt;/em&gt; can treat diabetes. However, seed shell of &lt;em&gt;Archidendron bubalinum&lt;/em&gt; has not yet to be scientifically proven and confirmed their ability to treat diabetes. The study of the potential of this seed shell was also scarcely available. &lt;strong&gt;Objective:&lt;/strong&gt; The recent work was aimed to investigate the phytochemical screening of methanol extracts of seed shells of &lt;em&gt;Archidendron bubalinum&lt;/em&gt; and to evaluate their chemical compositions and antidiabetic activities. &lt;strong&gt;Material and Methods:&lt;/strong&gt; The methods of phytochemical screening were including alkaloids, flavonoids, tannins, polyphenols, saponins, and terpenoids. Their chemical compositions were determined by Liquid Chromatography-Mass Spectrometry (LC-MS) and antidiabetic activities were performed by &amp;alpha;-glucosidase inhibitory method. &lt;strong&gt;Results:&lt;/strong&gt; The phytochemical screening showed that methanol extracts of seed shells of &lt;em&gt;Archidendron bubalinum&lt;/em&gt; contain flavonoids, tannins, polyphenols, and terpenoids. This extracts exhibited antidiabetic activity with IC&lt;sub&gt;50&lt;/sub&gt; 7.77 &amp;mu;g/mL. This result was supported by LC-MS analysis which showed the presence of phlorizin and astilbin, in which these compounds had high inhibitory activity against &amp;alpha;-glucosidase or diabetes.&lt;strong&gt; Conclusion:&lt;/strong&gt; LC-MS analysis revealed the presence of polyphenol compounds namely phlorizin and astilbin in which had high &amp;alpha;-glucosidase inhibitory activity, might largely contribute in the antidiabetic activity. Key words: Phytochemical screening, Mass spectrometry&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s77</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Hanafi&lt;sup&gt;1&lt;/sup&gt;, Candra Irawan&lt;sup&gt;2&lt;/sup&gt;, Henny Rochaeni&lt;sup&gt;2&lt;/sup&gt;, Lilis Sulistiawaty&lt;sup&gt;2&lt;/sup&gt;, Achmad Nandang Roziafanto&lt;sup&gt;2&lt;/sup&gt;, Supriyono&lt;sup&gt;2*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt; 1&lt;/sup&gt;Departement of Food Industrial Quality Assurance, Politeknik AKA Bogor, Bogor 16154, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Chemical Analysis, Politeknik AKA Bogor, Bogor 16154, INDONESIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sanwar Mal Lamba,</style></author><author><style face="normal" font="default" size="100%">Kunjbihari Sulakhiya,</style></author><author><style face="normal" font="default" size="100%">Parveen Kumar,</style></author><author><style face="normal" font="default" size="100%">Mangala Lahkar,</style></author><author><style face="normal" font="default" size="100%">Chandana C. Barua,</style></author><author><style face="normal" font="default" size="100%">Babul Bezbaruah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anti-diabetic, Hypolipidemic and Anti-oxidant Activities of Hydroethanolic Root Extract of Rhus Mysurensis Heyne in Streptozotocin Induced Diabetes in Wistar Male Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-diabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-oxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypolipidemic</style></keyword><keyword><style  face="normal" font="default" size="100%">Rhus mysurensis.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">8th April 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">62-71</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objectives:&lt;/strong&gt; The present study was designed to investigate the potential role of hydroethanolic root extracts&amp;nbsp; were &lt;em&gt;Rhus mysurensis&lt;/em&gt; (HERM) in the treatment of diabetes along with its antioxidant and antihyperlipidemic effects was studied in streptozotocin induced diabetes in Wistar rats. &lt;strong&gt;Methods:&lt;/strong&gt; In this study, the anti-diabetic, hypolipidemic and anti-oxidant activities of hydroethanolic root extract of&lt;em&gt; Rhus mysurensis&lt;/em&gt; was evaluated by using STZ induced diabetic rats at a dose of 200 mg/kg, 400 mg/kg and 800 mg/kg p.o. daily for 21 days. Blood glucose levels and body weight were monitored at specific time intervals, and different biochemical parameters, serum cholesterol, serum triglyceride, high density lipoprotein, low density lipoprotein were also assessed in the experimental animals.&lt;strong&gt; Results:&lt;/strong&gt; Oral administration of hydroethanolic root extracts of&lt;em&gt; Rhus mysurensis&lt;/em&gt; (HERM) 400 and 800 mg/kg for 21 days significantly decreased the blood glucose level and considerably increased the body weight of diabetic induced rats. Daily oral treatment with HERM for 3 weeks resulted in reduced serum cholesterol, and triglycerides and improved HDL-cholesterol levels when compared to the diabetic control group. HERM significantly decreased thiobarbituric acid reactive substances (TBARS) and significantly increased superoxide dismutase and catalase in streptozotocin-induced diabetic rats at the end of 21 days of treatment. &lt;strong&gt;Conclusion:&lt;/strong&gt; Hydroethanolic root extract of &lt;em&gt;Rhus mysurensis&lt;/em&gt; showed significant anti-diabetic, hypolipidemic and anti-oxidant activities, which provide the scientific proof for its traditional claims. The results also put forward that the HERM is promising for development of standardized phytomedicine for the treatment of diabetes mellitus.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words: &lt;/strong&gt;Anti-diabetic, anti-oxidant, hypolipidemic, &lt;em&gt;Rhus mysurensis&lt;/em&gt;.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sanwar Mal Lamba&lt;sup&gt;1#&lt;/sup&gt;, Kunjbihari Sulakhiya&lt;sup&gt;1#&lt;/sup&gt;, Parveen Kumar&lt;sup&gt;1#*&lt;/sup&gt;, Mangala Lahkar&lt;sup&gt;2&lt;/sup&gt;, Chandana C. Barua&lt;sup&gt;3&lt;/sup&gt; and Babul Bezbaruah&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;2&lt;/strong&gt;&lt;/sup&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Laboratory of Molecular Pharmacology and Toxicology, Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), GMC IIIrd Floor, Bhangagarh, Guwahati- 781032, India&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of Pharmacology, Department of Pharmacology, Gauhati Medical College, Bhangagarh, Guwahati-781032, India&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacology &amp;amp; Toxicology, College of Veterinary Sciences, Khanapara, Guwahati-781022.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Bhanu Priya,</style></author><author><style face="normal" font="default" size="100%">Manoj Gahlot,</style></author><author><style face="normal" font="default" size="100%">Punam Joshi,</style></author><author><style face="normal" font="default" size="100%">Sarika Zade,</style></author><author><style face="normal" font="default" size="100%">Ujwala Bagmar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of Anti-Diabetic Activity of Methanolic Extract from the Leaves of Rotula Aquatica Lour in Alloxan-Induced Diabetic Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alloxan</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-diabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Glibenclamide</style></keyword><keyword><style  face="normal" font="default" size="100%">Rotula aquatica lour.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">18th Feb,2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">110-114</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The objective of the present study was to evaluate the anti-diabetic activity of methanolic extract from the leaves of &lt;em&gt;Rotula aquatica lour&lt;/em&gt; in Alloxan-induced diabetic rats.&lt;strong&gt; Materials and Methods: &lt;/strong&gt;Diabetes was induced in rat by injection of Alloxan (120 mg/kg, i.p.). Diabetic rats were divided into different groups and methanolic leaves extract of &lt;em&gt;Rotula aquatica lour&lt;/em&gt; (RA-ME) was administered at dose ranges of 100&amp;ndash;400 mg/kg, p.o for 21 days. Control group received normal saline (0.9%) for 21 days. Glibenclamide (5 mg/kg, p.o) was used as standard drug. Blood samples were collected from all the groups and analyzed for serum glucose and lipid levels such as total cholesterol (TC), triglyceride (TG), proteins (TP). RA-ME was also tested for oral glucose tolerance test (OGTT) in normal fasted rats. &lt;strong&gt;Results:&lt;/strong&gt; RA-ME (400 mg/kg, p.o) showed a significant (&lt;em&gt;P&lt;/em&gt;&amp;lt;0.01) reduction of serum glucose level in Alloxan-induced diabetic mice as compared with diabetic control. RA-ME (200 and 400 mg/kg) also showed a significant reduction in serum TC, TG, and TP levels in Alloxan-induced diabetic rats. RA-ME (200 and 400 mg/kg, p.o) significantly (&lt;em&gt;P&lt;/em&gt;&amp;lt;0.01) increased the glucose tolerance in OGTT. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results obtained from the present study revealed the potential anti-diabetic activity of methanolic extract from the leaves of &lt;em&gt;Rotula aquatica lour&lt;/em&gt;.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Key words:&lt;/strong&gt; Alloxan, Anti-diabetic, Glibenclamide, &lt;em&gt;Rotula aquatica lour&lt;/em&gt;.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">110</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Bhanu Priya&lt;sup&gt;*,1&lt;/sup&gt;, Manoj Gahlot&lt;sup&gt;2&lt;/sup&gt;, Punam Joshi&lt;sup&gt;2&lt;/sup&gt;, Sarika Zade&lt;sup&gt;1&lt;/sup&gt; and Ujwala Bagmar&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;1&lt;/strong&gt;&lt;/sup&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Deptt of Pharmaceutical Chemistry, Sitabai Thite College of Pharmacy, Shirur, Pune-412210 (India)&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Deptt of Pharmaceutical Chemistry, S.G.R.R.I.T.S, Patel Nagar, Dehradun (Uttarakhand) India.&lt;/p&gt;</style></auth-address></record></records></xml>