<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Lubsandorzhieva PB</style></author><author><style face="normal" font="default" size="100%">Rendyuk TD</style></author><author><style face="normal" font="default" size="100%">Dashinamzhilov Zh.B</style></author><author><style face="normal" font="default" size="100%">Dargaeva TD</style></author><author><style face="normal" font="default" size="100%">Ferubko EV</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pharmacognostic Study of Collection and Study of its Hepatoprotective Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Hepatoprotective activity</style></keyword><keyword><style  face="normal" font="default" size="100%">microscopy</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolic compounds</style></keyword><keyword><style  face="normal" font="default" size="100%">standardization</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">713-721</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;The aim of this work is pharmacognostic study of herbal formulation consisting of elecampane rhizomes and roots (&lt;em&gt;Inula helenium&lt;/em&gt; L.), fruits of rose (&lt;em&gt;Rosa&lt;/em&gt; sp.) and hawthorn (&lt;em&gt;Crataegus&lt;/em&gt; sp.), leaves of pepper mint (&lt;em&gt;Mentha piperita&lt;/em&gt; L.) and cowberry leaves (&lt;em&gt;Vaccinium vitis-idaea&lt;/em&gt; L.), spiny eleuterococcus rhizomes and roots (&lt;em&gt;Eleutherococcus senticosus &lt;/em&gt;(Rupr.et Maxim.) Maxim., low cudweed herb (&lt;em&gt;Gnaphalium uliginosum&lt;/em&gt; L.s.l.) as well as determination of its hepatoprotective activity. &lt;strong&gt;Materials and methods: &lt;/strong&gt;An electron microscope, HPLC and methods of the State Pharmacopoeia of Russia were used in pharmacognostic study of herbal formulation. The hepatoprotective, antioxidant and choleretic activities of the herbal formulation were studied&lt;em&gt; in vivo&lt;/em&gt; model of liver damage induced by tetracycline hydrochloride and 40% ethanol. &lt;strong&gt;Results: &lt;/strong&gt;The content of biologically active substances (BAS) collected: essential oils - at least 0.30%; flavonoids in terms of luteolin - not less than 1.0%; ascorbic acid - not less than 0.5%; tannins - not less than 3.0%; arbutin - at least 0.4%; eleutheroside B - not less than 0.01%.It has been found that the course administration of herbal formulation to white Wistar rats with liver damage eliminates the prooxidant effect of tetracycline and ethanol, reduces the manifestation of cholestasis and increases the rate of bile secretion for 1-3 hours. &lt;strong&gt;Conclusion: &lt;/strong&gt;The herbal formulation has hepatoprotective activity, antioxidant, choleretic effect and stimulates regenerative and antitoxic processes in the liver in rats with a model of combined liver damage induced tetracycline and ethanol. The obtained research results argue the possibility of using herbal formulation for prevention and complex treatment of liver diseases.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">713</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Lubsandorzhieva PB&lt;sup&gt;1,&lt;/sup&gt;*, Rendyuk TD&lt;sup&gt;2&lt;/sup&gt;, Dashinamzhilov Zh.B&lt;sup&gt;1&lt;/sup&gt;, Dargaeva TD&lt;sup&gt;3&lt;/sup&gt;, Ferubko EV&lt;sup&gt;3&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Institute of General and Experimental Biology of the Siberian Branch of the RAS, Ulan-Ude, RUSSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Sechenov First Moscow State Medical University, Moscow, RUSSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;All-Russian Research Institute of medicinal and Aromatic Plants, Moscow, RUSSIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ravi Kumar Vakkalagadda</style></author><author><style face="normal" font="default" size="100%">Parameshwar Ravula</style></author><author><style face="normal" font="default" size="100%">Kondapuram Parameshwar</style></author><author><style face="normal" font="default" size="100%">Kaspa Saraswathi</style></author><author><style face="normal" font="default" size="100%">P Sindhuri</style></author><author><style face="normal" font="default" size="100%">Rajala Srikala</style></author><author><style face="normal" font="default" size="100%">Kosika Sandeep</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Protective Potential of Canthium dicoccum Methanolic Extract Against Hepatic Injury in Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant enzymes</style></keyword><keyword><style  face="normal" font="default" size="100%">Canthium dicoccum</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatoprotective activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Liver markers</style></keyword><keyword><style  face="normal" font="default" size="100%">Paracetamol.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1648-1655</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The methanolic extract of leaves of &lt;em&gt;C.dicoccum&lt;/em&gt; was evaluated for its hepatoprotective activity against paracetamol induced hepatotoxicity since it is reported to cause oxidative stress in the animal thereby altering the enzymatic levels. Fresh leaves were collected, shade dried and extract was prepared by cold maceration followed by drying in a rota-vapour using methanol to obtain MECD as a sticky semi-solid mass. Thirty rats were taken and divided into 5 equal groups where, Group I, II, and III served as Normal Control, Negative control (PCM 3g/kg), and Positive control (Silymarin 200mg/kg) respectively; whereas, Group IV and V served as test groups where the rats were pre-treated orally with MECD 200mg/kg and 400mg/kg respectively for six days before administering PCM. On the 8&lt;sup&gt;th&lt;/sup&gt; day all groups except Group I was administered with PCM (3g/kg). 48 hours post PCM induction, the animals were anesthetized, blood samples were obtained via retro-orbital sinus plexus and then the rats were sacrificed. The serum was assessed for the evaluation parameters like AST, ALT, ALP, and bilirubin levels. Apart from these; SOD, CAT, and MDA levels were also evaluated and it was concluded that treatment with MECD restored the levels to normal thereby exhibiting hepatoprotective activity. Moreover, histopathological evaluation was carried out to assess the liver for inflammation, infiltration, or necrosis where the MECD treated rats showed promising results.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1648</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ravi Kumar Vakkalagadda&lt;sup&gt;1,2,&lt;/sup&gt;*, Parameshwar Ravula&lt;sup&gt;3&lt;/sup&gt;, Kondapuram Parameshwar&lt;sup&gt;1,2&lt;/sup&gt;, Kaspa Saraswathi&lt;sup&gt;1,2&lt;/sup&gt;, P Sindhuri&lt;sup&gt;1&lt;/sup&gt;, Rajala Srikala&lt;sup&gt;1&lt;/sup&gt;, Kosika Sandeep&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Pharmacy, Guru Nanak Institutions Technical Campus, Ibrahimpatnam, Hyderabad, Telangana, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Research Scholar, GITAM Institute of Pharmacy, GITAM University, Rushikonda, Visakhapatnam, Andhra Pradesh, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmaceutical Chemistry, Amity Institute of Pharmacy, Amity University, Gwalior, Madhya Pradesh, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Thriveni Vasanthkumar</style></author><author><style face="normal" font="default" size="100%">Manjunatha Hanumanthappa</style></author><author><style face="normal" font="default" size="100%">Prabhakar BT</style></author><author><style face="normal" font="default" size="100%">Santhosh Kondajji Hanumanthappa</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective Effect of Curcumin and Capsaicin against Lipopolysaccharide Induced Liver Damage in Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">ALP.</style></keyword><keyword><style  face="normal" font="default" size="100%">Capsaicin</style></keyword><keyword><style  face="normal" font="default" size="100%">Curcumin</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatoprotective activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipopolysaccharide</style></keyword><keyword><style  face="normal" font="default" size="100%">SGOT</style></keyword><keyword><style  face="normal" font="default" size="100%">SGPT</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/201</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">947-951</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The present study was undertaken to evaluate the possible ameliorative role of curcumin, capsaicin and their combination against lipopolysaccharide (LPS) induced hepatic toxicity in mice. &lt;strong&gt;Methods:&lt;/strong&gt; Animals were distributed into five experimental groups: Normal control, vehicle control, curcumin, capsaicin and combined curcumin and capsaicin treatment groups respectively, for 7 days prior to LPS induced liver toxicity (3 mg/kg b.w. in saline). Hepatoprotective effect of individual and combined spice principles were evidenced by the measurement of serum marker enzyme activities such as, SGPT, ALP and TB and it was further confirmed by histopathological observation of liver tissue section. &lt;strong&gt;Results:&lt;/strong&gt; The administration of LPS increased serum nonspecific enzymes (SGOT; 174.2&amp;plusmn;3.79 IU/L, SGPT; 124.0&amp;plusmn;3.14 IU/L, ALP; 320.15&amp;plusmn;3.88 IU/L and total bilirubin level; 2.32&amp;plusmn;1.23 mg/dL), however dietary curcumin and capsaicin decreased the activities of these non&amp;ndash;specific serum enzymes including total bilirubin indicating amelioration of the severe LPS induced hepatotoxicity, while the combined spice principles were more significant as shown by the levels of enzymes activities SGOT; 89.9&amp;plusmn;1.39 IU/L, SGPT; 85.9&amp;plusmn;1.83 IU/L, ALP; 138.4&amp;plusmn;2.05 IU/L including total bilirubin level; 0.86&amp;plusmn;0.03 mg/dL. &lt;strong&gt;Conclusion:&lt;/strong&gt; Dietary curcumin and capsaicin individually are protective to LPS induced hepatotoxicity, the beneficial effect was found to be more when the two compounds were fed in combination.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">947</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Thriveni Vasanthkumar&lt;sup&gt;1&lt;/sup&gt;, Manjunatha Hanumanthappa&lt;sup&gt;1&lt;/sup&gt;, Prabhakar BT&lt;sup&gt;2&lt;/sup&gt;, Santhosh Kondajji Hanumanthappa&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biotechnology, Kuvempu University, Shankaraghatta - 577 451 Shimoga, Karnataka (St), INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Molecular biomedicine laboratory, Postgraduate department of studies and research in biotechnology, Sahyadri science college, Kuvempu University, Shimoga-577203, Karnataka (St), INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Somnath De</style></author><author><style face="normal" font="default" size="100%">Ramalingam Suresh</style></author><author><style face="normal" font="default" size="100%">Akula Murali Sri Sudhakar Babu</style></author><author><style face="normal" font="default" size="100%">Siddabathuni Aneela</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">In-vivo Hepatoprotective Activity of Methanolic Extracts of Sphaeranthus amaranthoides and Oldenlandia umbellate</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">ALP</style></keyword><keyword><style  face="normal" font="default" size="100%">CCl4</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatoprotective activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Oldenlandia umbellata</style></keyword><keyword><style  face="normal" font="default" size="100%">SGOT</style></keyword><keyword><style  face="normal" font="default" size="100%">SGPT</style></keyword><keyword><style  face="normal" font="default" size="100%">Sphaeranthus amaranthoides</style></keyword><keyword><style  face="normal" font="default" size="100%">TB.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">98-101</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;div style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The present study was carried out to evaluate the&lt;em&gt; in vitro&lt;/em&gt; hepatoprotective activity of unexploited plants, &lt;em&gt;Sphaeranthus amaranthoides&lt;/em&gt; and &lt;em&gt;Oldenlandia umbellate&lt;/em&gt;&amp;nbsp;on CCl&lt;sub&gt;4&lt;/sub&gt; induced liver injury, which are indigenous to South India.&lt;strong&gt; Methods:&lt;/strong&gt; in the present study the methanolic extracts from &lt;em&gt;Sphaeranthus amaranthoides&lt;/em&gt; and &lt;em&gt;Oldenlandia umbellata&lt;/em&gt; were studied against the carbon tetrachloride hepatotoxicity. &lt;strong&gt;Results:&lt;/strong&gt; significant hepatoprotective effect was obtained against carbon tetrachloride induced liver damage as judged from serum marker enzyme activities (SGOT, SGPT, ALT, and TB) and a normal architecture of liver compare to toxic control. &lt;strong&gt;Conclusion:&lt;/strong&gt; the result revealed that methanolic extracts of &lt;em&gt;Sphaeranthus amaranthoides&lt;/em&gt; and &lt;em&gt;Oldenlandia umbellata&lt;/em&gt; could be useful in preventing CCl&lt;sub&gt;4&lt;/sub&gt; induced liver injury.&lt;/div&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">98</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Somnath De&lt;sup&gt;1&lt;/sup&gt;*, Ramalingam Suresh&lt;sup&gt;2&lt;/sup&gt;, Akula Murali Sri Sudhakar Babu&lt;sup&gt;3&lt;/sup&gt;, Siddabathuni Aneela&lt;sup&gt;1 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Dr. Samuel George Institute of Pharmaceutical Sciences, Markapur- 523316, Andhra Pradesh, India &lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Annamalai University, Department of Pharmacy, Annamalai Nagar-600 802, Tamil Nadu, India &lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;A.M. Reddy Memorial Colleges of Pharmacy, Narasaraopet, Guntur-522601, Andhra Pradesh&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rajagopal Ramasubramania raja</style></author><author><style face="normal" font="default" size="100%">Koumara Velou Kailasam</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Abutilon indicum L (Malvaceae)-Medicinal Potential Review</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Abutilon indicum</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti asthmatic</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-proliferative activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatoprotective activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolic compounds</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Nov-Dec 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">330-332</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;The plant Abutilon Indicum (Linn.) is belonging to malvaceae family; Also known as Mallow in english, Abutilon indicum is used as a medicinal plant. It has been reported that Abutilon indicum has Anti inflammatory and Antiproliferative activity, Anti-Arthritic activity, Analgesic and Sedative property, Antioxidant and Antimicrobial activity, Hepatoprotective activity, Anti diabetic, Anti cancer, Anti diarrhoeal, Anti-convulsant, Larvicidal, Wound healing, Anti asthmatic, Diuretic, Immunomodulatory, and Anti-estrogenic activity. It is proved that this plant contains carbohydrates, proteins and aminio acids, saponins, flavanoids, glycosides, phytosterols and phenolic compounds&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">330</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Rajagopa&lt;sup&gt;l&lt;/sup&gt; Ramasubramania raja&lt;sup&gt;*1&lt;/sup&gt; and Koumara Velou Kailasam&lt;sup&gt;2&lt;/sup&gt; &lt;/strong&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacy, Research Scholar PRIST University, Thanjavur, T.N, India. 2Registrar, PRIST University, Thanjavur, T.N, India&lt;/p&gt;</style></auth-address></record></records></xml>