<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dwi Kusuma Wahyuni</style></author><author><style face="normal" font="default" size="100%">Anindya Nariswari</style></author><author><style face="normal" font="default" size="100%">Agus Supriyanto</style></author><author><style face="normal" font="default" size="100%">Hery Purnobasuki</style></author><author><style face="normal" font="default" size="100%">Hunsa Punnapayak</style></author><author><style face="normal" font="default" size="100%">Wichanee Bankeeree</style></author><author><style face="normal" font="default" size="100%">Sehanat Prasongsuk</style></author><author><style face="normal" font="default" size="100%">Wiwied Ekasari</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant, Antimicrobial, and Antiplasmodial Activities of Sonchus arvensis L. Leaf Ethyl Acetate Fractions</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Biological activities</style></keyword><keyword><style  face="normal" font="default" size="100%">Escherichia coli.</style></keyword><keyword><style  face="normal" font="default" size="100%">Malaria</style></keyword><keyword><style  face="normal" font="default" size="100%">Plasmodium falciparum</style></keyword><keyword><style  face="normal" font="default" size="100%">Sonchus arvensis L.</style></keyword><keyword><style  face="normal" font="default" size="100%">Staphylococcus aureus</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">993-998</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Infection is one of the health problems and a disease that mainly causes death. Malaria is a parasitic infection that is transmitted through the Anopheles sp. The female then causes infection and besides malaria, other contaminants that caused infection are bacteria such as&lt;em&gt; Escherichia coli&lt;/em&gt; and &lt;em&gt;Staphylococcus aureus&lt;/em&gt;. This study aims to determine the antioxidant, antimicrobial, and antiplasmodial activity of &lt;em&gt;Sonchus arvensis&lt;/em&gt; L. ethyl acetate fractions. &lt;em&gt;In vitro &lt;/em&gt;antiplasmodial activity was carried out by Rieckman methods against Plasmodium falciparum strain 3D7&lt;em&gt;. In vitro&lt;/em&gt; antioxidant activity was conducted by Prieto method against (1,1-diphenyl-2-picrylhydrazyl (DPPH). Then antimicrobial activity was performed using well diffusion method against &lt;em&gt;Escherichia coli &lt;/em&gt;and &lt;em&gt;Staphylococcus aureus. &lt;/em&gt;Maceration of &lt;em&gt;S. arvensis&lt;/em&gt; L. dried leaves used n-hexane and ethyl acetate successively. Then the ethyl acetate extract was fractionated by vacuum column chromatography, using n-hexane and ethyl acetate as mobile phases. There are five fraction groups based on thin-layer chromatography (TLC) analysis. The IC&lt;sub&gt;50 &lt;/sub&gt;of antioxidant and antiplasmodial activity showed that fraction IV was the lowest value and categorized as active for antioxidant (IC&lt;sub&gt;50&lt;/sub&gt;=22.56 μg/mL), for antiplasmodial (IC&lt;sub&gt;50&lt;/sub&gt;=12.07 μg/mL). Fraction IV also had antimicrobial activity, with diameter of inhibition zone (DIZ) of 19.22 mm against Escherichia coli and 17.167 mm against &lt;em&gt;Staphylococcus aureus.&lt;/em&gt;&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><section><style face="normal" font="default" size="100%">993</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Dwi Kusuma Wahyuni&lt;sup&gt;1,*&lt;/sup&gt;, Anindya Nariswari&lt;sup&gt;1&lt;/sup&gt;, Agus Supriyanto&lt;sup&gt;1&lt;/sup&gt;, Hery Purnobasuki&lt;sup&gt;1&lt;/sup&gt;, Hunsa Punnapayak&lt;sup&gt;1,2&lt;/sup&gt;, Wichanee Bankeeree&lt;sup&gt;2&lt;/sup&gt;, Sehanat Prasongsuk&lt;sup&gt;1,2,*&lt;/sup&gt;, Wiwied Ekasari&lt;sup&gt;3,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biology, Faculty of Science and Technology, Airlangga University Surabaya, East Java, 60115, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Plant Biomass Utilization Research Unit, Department of Botany, Faculty of Science, Chulalongkorn University, Bangkok, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmaceutical Science, Faculty of Pharmacy, Airlangga University Surabaya, East Java, 60115, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Marilú Roxana Soto-Vásquez</style></author><author><style face="normal" font="default" size="100%">Madeleine Vanessa Horna -Pinedo</style></author><author><style face="normal" font="default" size="100%">Luciana R Tallini</style></author><author><style face="normal" font="default" size="100%">Jaume Bastida</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Chemical Composition and In Vitro Antiplasmodial Activity of the Total Alkaloids of the Bulbs of Two Amaryllidaceae Species from Northern Peru</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Clinanthus incarnatus</style></keyword><keyword><style  face="normal" font="default" size="100%">Clinanthus ruber</style></keyword><keyword><style  face="normal" font="default" size="100%">Plasmodium falciparum</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1046-1052</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; The amaryllidaceae family is characterized by presenting alkaloids with powerful pharmacological activities, including antiprotozoal activity. The aim of the present work was to determine the chemical composition and evaluate the in vitro antiplasmodial activity of the total alkaloids of the bulbs of two amaryllidaceae species from northern Perú. &lt;strong&gt;Methods: &lt;/strong&gt;The total alkaloids were extracted from the bulbs using an acid-base extraction. The chemical composition of the total alkaloids was determined by GC-MS, using galantamine as a reference standard. It was investigated the in vitro antiplasmodial activity against &lt;em&gt;Plasmodium falciparum&lt;/em&gt; FCR-3 strain (chloroquine-resistant). &lt;strong&gt;Results:&lt;/strong&gt; 8 alkaloids were identified in the bulbs of &lt;em&gt;Clinanthus incarnatus&lt;/em&gt;: lycorine, galanthamine, galanthine, vittatine/crinine, hippamine, 3-O-acetylpowelline, 11,12-dehydroanhydrolycorine, 1-O-acetyllycorine with values of 19.73; 14.99; 10.36; 10.22; 10.16; 10.14; 10.04; 9.85 μg GAL/100 mg of total alkaloid (TA) respectively and 6 alkaloids in the bulbs of &lt;em&gt;Clinanthus ruber:&lt;/em&gt; lycorine, anhydrolycorine, 11,12-dehydroanhydrolycorine, 2,4-didehydro-2-dehydroxylycorine, 8-0-dimethylmaritidine, hippamine, with values of 70.2; 18; 4.15; 3.45; 6.8 and 0.1 μg GAL/100 mg TA respectively. The total alkaloids of the species of C. incarnatus and &lt;em&gt;C. ruber&lt;/em&gt; at concentrations of 1.0; 2.5; 5.0; 10.0; 25.0 and 50.0 μg/ml presented inhibition percentages of 23.5 ± 0.46% to 94 ± 0.56% against &lt;em&gt;P. falciparum&lt;/em&gt; with (p &amp;lt;0.05). They also presented IC&lt;sub&gt;50 &lt;/sub&gt;0.375 μg/ml (C. incarnatus) and IC&lt;sub&gt;50&lt;/sub&gt; 0.241 μg / ml (&lt;em&gt;C. ruber&lt;/em&gt;). &lt;strong&gt;Conclusion:&lt;/strong&gt; The main component of total alkaloids of the bulbs of two species was lycorine, in adittion, these species showed in vitro antiplasmoidal activity against Plasmodium falciparum FCR-3 strain at the doses tested.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1046</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Marilú Roxana Soto-Vásquez&lt;sup&gt;1,&lt;/sup&gt;*, Madeleine Vanessa Horna -Pinedo&lt;sup&gt;1&lt;/sup&gt;, Luciana R. Tallini&lt;sup&gt;2&lt;/sup&gt;, Jaume Bastida&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Facultad de Farmacia y Bioquímica. Universidad Nacional de Trujillo, Trujillo, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre RS 90610- 000, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hadi Kuncoro</style></author><author><style face="normal" font="default" size="100%">Aty Widyawaruyanti</style></author><author><style face="normal" font="default" size="100%">Taslim Ersam</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Alpha-Mangostin Effect on Inhibition Development Stadium and Globin Accumulation Against Plasmodium falciparum</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Development stage inhibition</style></keyword><keyword><style  face="normal" font="default" size="100%">Garcinia tetrandra</style></keyword><keyword><style  face="normal" font="default" size="100%">Plasmodium falciparum</style></keyword><keyword><style  face="normal" font="default" size="100%">SDS-PAGE</style></keyword><keyword><style  face="normal" font="default" size="100%">α-mangostin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/670</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">783-788</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&amp;alpha;--Mangostin is a widely reported group of Xanthone compounds from the Clusiaceae family of 40 genera and over 1000 species spread across the tropics and subtropics area. The Objective for determine effect of &amp;alpha;-mangostin from &lt;em&gt;Garcinia tetrandra&lt;/em&gt; Pierre stem bark against development stadium inhibition and globin accumulation of &lt;em&gt;Plasmodium falciparum&lt;/em&gt;. Inhibition stadium development assay used based on the Rosenthal method. &lt;em&gt;Plasmodium falciparum&lt;/em&gt; parasitic globin accumulation assay. Globin accumulation assay used the highest concentration of in vitro antimalarial test using SDS-PAGE with positive control E-64 and &amp;alpha;-mangostin were incubated together with the malaria parasite during 24 h. Result of Inhibition stadium development of Plasmodium falciparum against &amp;alpha;-mangostin show inhibition from development stadium of the malaria parasite &lt;em&gt;Plasmodium falciparum&lt;/em&gt;, Electrophoresis show globin accumulation from electrophoresis followed by staining using &lt;em&gt;Coomassie brilliant blue&lt;/em&gt;. &amp;alpha;-mangostin showed inhibition the growth of malaria parasite &lt;em&gt;Plasmodium falciparum&lt;/em&gt; with dose 10 &amp;mu;g/ml is expected to occur a large accumulation of globin, which can be viewed both morphologically and by the method of SDS-PAGE.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">783</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Hadi Kuncoro&lt;sup&gt;1&lt;/sup&gt;*, Aty Widyawaruyanti&lt;sup&gt;2&lt;/sup&gt;, Taslim Ersam&lt;sup&gt;3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Laboratorium Penelitian dan Pengembangan Kefarmasian FARMAKA TROPIS, Fakultas Farmasi, Mulawarman University, Samarinda 75119, East Kalimantan, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Airlangga University, Surabaya, 60286, Indonesia, Center for Natural Product Medicine Research and Development, Institute of Tropical Disease, Airlangga University, Surabaya 60115, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Chemistry, Faculty of Mathematics and Natural Sciences, Institut Teknologi Sepuluh November, Kampus ITS-Sukolilo, Surabaya 60111, INDONESIA.&lt;/p&gt;</style></auth-address></record></records></xml>