<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Agung Widiyanto</style></author><author><style face="normal" font="default" size="100%">Effionora Anwar</style></author><author><style face="normal" font="default" size="100%">Tati Nurhayati</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">In vitro Assay of Alpha-Glucosidase Inhibitor Activities of Three Seagrasses from Banten Bay, Indonesia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Cymodocea rotundata</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetes mellitus</style></keyword><keyword><style  face="normal" font="default" size="100%">Enhalus acoroides</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical compound</style></keyword><keyword><style  face="normal" font="default" size="100%">Thalassia hemprichii</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">907-910</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Diabetes mellitus (DM) is an endocrine disorder characterized by high blood glucose levels. One of the approaches for treating DM is by regulating the postprandial blood glucose via inhibition of &amp;alpha;-glucosidase enzymes. Seagrass is known as a plant containing bioactive compounds, especially for therapy antidiabetic. This research aims to evaluate the &amp;alpha;-glucosidase inhibition activity of three species seagrasses (&lt;em&gt;Enhalus acoroides, Thalassia hemprichii&lt;/em&gt; and &lt;em&gt;Cymodocea rotundata&lt;/em&gt;) from the Banten Bay, Indonesia. &lt;strong&gt;Methods:&lt;/strong&gt; The extracts of all parts (root, leaf, and stem) from three seagrasses were prepared with maceration method using 80% ethanol solvents. The &amp;alpha;-glucosidase inhibitory activity was conducted by microplate reader at 400 nm using acarbose as a positive control. Furthermore, the kinetics of &amp;alpha;-glucosidase inhibition, phytochemical screening, and total phenolics content were evaluated against extract which has the most potential &amp;alpha;-glucosidase inhibition. &lt;strong&gt;Results:&lt;/strong&gt; The result showed that the 80% ethanol extracts of &lt;em&gt;Enhalus acoroides&lt;/em&gt; (IC&lt;sub&gt;50&lt;/sub&gt; values 168.15 &amp;plusmn; 2.71 &lt;em&gt;&amp;mu;&lt;/em&gt;g/mL) had the most potential &amp;alpha;-glucosidase inhibitors activity compared with the positive control acarbose, &lt;em&gt;Thalassia hemprichii&lt;/em&gt; and &lt;em&gt;Cymodocea rotundata&lt;/em&gt; (IC&lt;sub&gt;50&lt;/sub&gt; values 197.27 &amp;plusmn; 3.07 &lt;em&gt;&amp;mu;&lt;/em&gt;g/mL, 425.86 &amp;plusmn; 5.15 &lt;em&gt;&amp;mu;&lt;/em&gt;g/mL and 429.28 &amp;plusmn; 8.89 &lt;em&gt;&amp;mu;&lt;/em&gt;g/mL). The kinetic type of inhibition against &amp;alpha;-glucosidase was noncompetitive inhibition. The phytochemical compounds were phenols, flavonoid, terpenes, and tannin with the total phenolic content was 28.76 &amp;plusmn; 2.46 mgGAE/g. &lt;strong&gt;Conclusion:&lt;/strong&gt; &lt;em&gt;Enhalus acoroides&lt;/em&gt; has the strongest inhibitor of &amp;alpha;-glucosidase and can be further developed for DM therapy agents.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">907</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Agung Widiyanto&lt;sup&gt;1&lt;/sup&gt;, Effionora Anwar&lt;sup&gt;1*&lt;/sup&gt;, Tati Nurhayat&lt;sup&gt;i2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, University of Indonesia, Depok 16424, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Aquatic Products Technology, Bogor Agricultural University, Bogor 16680, INDONESIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Supattra Klangprapun</style></author><author><style face="normal" font="default" size="100%">Benjaporn Buranrat</style></author><author><style face="normal" font="default" size="100%">Wanida Caichompoo</style></author><author><style face="normal" font="default" size="100%">Somsak Nualkaew</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pharmacognostical and Physicochemical Studies of Enhalus acoroides (L.F.) Royle (Rhizome)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Enhalus acoroides</style></keyword><keyword><style  face="normal" font="default" size="100%">Macroscopic</style></keyword><keyword><style  face="normal" font="default" size="100%">Microscopic</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacognostic</style></keyword><keyword><style  face="normal" font="default" size="100%">Specification</style></keyword><keyword><style  face="normal" font="default" size="100%">standardization</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">s89-s94</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; The rhizome of&lt;em&gt; Enhalus acoroides&lt;/em&gt; (L.f.) Royle is used in traditional medicine for treatment of many diseases e.g. muscle pains, wounds and stomach problems where pharmacognostical studies are lacking. Many chemical constituents; luteolin, apigenin, luteolin glycosides, stigmasterol, daucosterol have been reported. The aim of this work was to perform a pharmacognostical evaluation. &lt;strong&gt;Methods:&lt;/strong&gt; Macroscopical, microscopical and physicochemical parameters were assessed.&lt;strong&gt; Results:&lt;/strong&gt; &lt;em&gt;E. acoroides&lt;/em&gt; has characteristic morphology. Microscopical studies indicated the presence of vessels, fiber, parenchyma cells, sclereids, tracheids and trichomes. Physicochemical parameters of &lt;em&gt;E. acoroides&lt;/em&gt; rhizome; foreign matter, loss on drying and total ash content were measured. As well as chemical investigation through TLC and HPLC were specified. &lt;strong&gt;Conclusion:&lt;/strong&gt; The present study of &lt;em&gt;E. acoroides&lt;/em&gt; rhizome provides useful information that can serve as a diagnostic tool for the standardization of &lt;em&gt;E. acoroides &lt;/em&gt;and will be helpful in characterization of the crude drug in the market.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s89</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Supattra Klangprapun&lt;sup&gt;1&lt;/sup&gt;, Benjaporn Buranrat&lt;sup&gt;1&lt;/sup&gt;, Wanida Caichompoo&lt;sup&gt;2&lt;/sup&gt;, Somsak Nualkaew&lt;sup&gt;2,* &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Medicine, Mahasarakham University, Mahasarakham, THAILAND.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Pharmaceutical Chemistry and Natural Product Research Unit, Faculty of Pharmacy, Mahasarakham University, Mahasarakham, THAILAND.&lt;/p&gt;</style></auth-address></record></records></xml>