<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Emy Koestanti Sabdoningrum</style></author><author><style face="normal" font="default" size="100%">Sri Hidanah</style></author><author><style face="normal" font="default" size="100%">Sri Chusniati</style></author><author><style face="normal" font="default" size="100%">Soeharsono</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Characterization and Phytochemical Screening of Meniran (Phyllanthus niruri Linn) Extract's Nanoparticles Used Ball Mill Method</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Biological production</style></keyword><keyword><style  face="normal" font="default" size="100%">Nanoparticle</style></keyword><keyword><style  face="normal" font="default" size="100%">Phyllanthus niruri</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical compound</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1568-1572</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The aim of this study was to study the characterization and phytochemical screening of meniran (&lt;em&gt;Phyllanthus niruri&lt;/em&gt; linn) extract's nanoparticles used ball mill method. The effect of herbal products would be maximized, a formulation that able to increase solubility, stability, bioavailability, and a targeted system was needed so the use of simplicia would be more effective. One of alternative solutions to this problem was to make the preparation of meniran extract in the form of nanoparticles. Nanoparticles made it easier for extract to be absorbed in blood plasma and were more effective in achieving the target drug itself. The manufacture of meniran nanoparticles used ball mill method. Then, meniran extract nanoparticles characterization and phytochemical screening were carried out. Meniran (&lt;em&gt;Phyllanthus niruri&lt;/em&gt; Linn) extract nanoparticle characterization consisted of size, used Particle Size Analyzer (PSA), and morphology, used Scaning Electron Microscope (SEM). Phytochemical screening of meniran extract nanoparticles used qualitative screening by reagent test. The results showed that the meniran extract nanoparticles produced an average size of 192.6 nm. The averange shape of particle was imperfectly amorphous and the dominant composition was Carbon (C). Phytochemical screening showed the content of flavonoids, tannins, saponins, terpenoids and alkaloids.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1568</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Emy Koestanti Sabdoningrum&lt;sup&gt;*&lt;/sup&gt;, Sri Hidanah, Sri Chusniati, Soeharsono&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sani Nurlaela Fitriansyah</style></author><author><style face="normal" font="default" size="100%">Irda Fidrianny</style></author><author><style face="normal" font="default" size="100%">Rika Hartati</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pharmacological Activities and Phytochemical Compounds: Overview of Pouteria Genus</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Pharmacological activities</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical compound</style></keyword><keyword><style  face="normal" font="default" size="100%">Pouteria genus</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">577-584</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Species of Pouteria are widely spread in various countries. Pouteria is one of the genus that have diverse pharmacological activities. This review includes an overview of the species from Pouteria, phytochemical methods used in isolation of compounds from Pouteria, and their pharmacological activities. The trends in the pharmacological activity of Pouteria is antioxidant activity, antidiabetic and antimicrobial activities. However, information on its use as a traditional medicine from Pouteria was poor. Chemical compounds that have been widely isolated from Pouteria genus included phenolic acid, other phenolics non flavonoid, flavonoids, and terpenoids derivative. The most widely reported chemical compounds from Pouteria are terpenoid derivatives. Further research is needed for the mechanism of action based on the pharmacological activites of chemical compounds.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">577</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sani Nurlaela Fitriansyah&lt;sup&gt;1,2,&lt;/sup&gt;*, Irda Fidrianny1, Rika Hartati&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Biology, School of Pharmacy, Bandung Institute of Technology, Bandung-40132, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmaceutical Biology, Indonesian School of Pharmacy (Sekolah Tinggi Farmasi Indonesia), Bandung-40226, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Bianca Priscilia</style></author><author><style face="normal" font="default" size="100%">Media Fitri Isma Nugraha</style></author><author><style face="normal" font="default" size="100%">Hessy Novita</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant and Antibacterial Assay Against Fish Pathogen Bacteria of Kjellbergiodendron celebicum (Koord.) Merr. Leaf Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Aeromonas hydrophila</style></keyword><keyword><style  face="normal" font="default" size="100%">Edwardsiella ictaluri</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavobacterium columnare</style></keyword><keyword><style  face="normal" font="default" size="100%">Maceration</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical compound</style></keyword><keyword><style  face="normal" font="default" size="100%">Ultrasonic-Assisted Extraction</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February  2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">173-179</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Kjellbergiodendron celebicum&lt;/em&gt; (Koord.) Merr. (local name: tombe uwa) is a plant endemic to Sulawesi, Indonesia, and grows around lakes or aquatic environments where fish live. Based on phytochemical screening in previous studies, i.e. methanol extract and ethyl acetate fraction from the leaves of &lt;em&gt;Kjellbergiodendron celebicum&lt;/em&gt; (Koord.) Merr., the methanol extract gives positive results containing polyphenol compounds in the flavonoid group which have been known to have strong antioxidant and antibacterial properties. &lt;strong&gt;Objective: &lt;/strong&gt;To test the effectiveness of the comparison of the natural content in the compounds (antibacterial and antioxidant properties) and the total content of phenol in &lt;em&gt;Kjellbergiodendron celebicum &lt;/em&gt;(Koord.) Merr., which was extracted using two methods, i.e. maceration and Ultrasonic- Assisted Extraction (UAE), in fish-disease bacteria. &lt;strong&gt;Method: &lt;/strong&gt;The leaves were separated to be extracted with two different methods: maceration and Ultrasound-Assisted Extraction (UAE). Extracts were first screened qualitatively for antioxidant activity and then quantified with respect to &lt;em&gt;in vitro &lt;/em&gt;antioxidant activity using the 2.2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay and the ferric-reducing antioxidant power (FRAP) assay. Antibacterial activity was determined by the paper disc diffusion method and microdilution.&lt;strong&gt; Results: &lt;/strong&gt;70% Ethanol in leaves extract of &lt;em&gt;Kjellbergiodendron celebicum&lt;/em&gt; (Koord.) Merr. The extract which has the highest activity based on the DPPH test and FRAP test is the extract from UAE extraction with IC&lt;sub&gt;50&lt;/sub&gt; value of 9.81512 μg/mL and ferrous equivalent antioxidant capacity (FeEAC) value of 1.661.3 μmol/gr. UAE method also has a higher potential in antibacterial activity based on the diffusion method of paper discs and microdilution with the MIC obtained as much as 390.6 μg/mL. &lt;strong&gt;Conclusion:&lt;/strong&gt; the UAE extraction method is better at scanning polyphenol compounds compared to the conventional maceration extraction method. Therefore, the results of the antioxidant and antibacterial activity using the UAE method are better than the maceration method.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">173</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Bianca Priscilia&lt;sup&gt;1&lt;/sup&gt;, Media Fitri Isma Nugraha&lt;sup&gt;2,&lt;/sup&gt;*, Hessy Novita&lt;sup&gt;3&lt;/sup&gt;, Berna Elya&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, University of Indonesia, Depok 16424 West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Indonesian Research Institute for Ornamental Fish Culture – the Ministry Marine and Fisheries, Jl. Perikanan No 13 Pancoran Mas Depok 16438 PO BOX 06 West Java INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Installation Pathology and Fish Disease – Ministry Marine and Fisheries. Jl Perikanan No 13 A Pancoran Mas Depok West Java INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Agung Widiyanto</style></author><author><style face="normal" font="default" size="100%">Effionora Anwar</style></author><author><style face="normal" font="default" size="100%">Tati Nurhayati</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">In vitro Assay of Alpha-Glucosidase Inhibitor Activities of Three Seagrasses from Banten Bay, Indonesia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Cymodocea rotundata</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetes mellitus</style></keyword><keyword><style  face="normal" font="default" size="100%">Enhalus acoroides</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical compound</style></keyword><keyword><style  face="normal" font="default" size="100%">Thalassia hemprichii</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">907-910</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Diabetes mellitus (DM) is an endocrine disorder characterized by high blood glucose levels. One of the approaches for treating DM is by regulating the postprandial blood glucose via inhibition of &amp;alpha;-glucosidase enzymes. Seagrass is known as a plant containing bioactive compounds, especially for therapy antidiabetic. This research aims to evaluate the &amp;alpha;-glucosidase inhibition activity of three species seagrasses (&lt;em&gt;Enhalus acoroides, Thalassia hemprichii&lt;/em&gt; and &lt;em&gt;Cymodocea rotundata&lt;/em&gt;) from the Banten Bay, Indonesia. &lt;strong&gt;Methods:&lt;/strong&gt; The extracts of all parts (root, leaf, and stem) from three seagrasses were prepared with maceration method using 80% ethanol solvents. The &amp;alpha;-glucosidase inhibitory activity was conducted by microplate reader at 400 nm using acarbose as a positive control. Furthermore, the kinetics of &amp;alpha;-glucosidase inhibition, phytochemical screening, and total phenolics content were evaluated against extract which has the most potential &amp;alpha;-glucosidase inhibition. &lt;strong&gt;Results:&lt;/strong&gt; The result showed that the 80% ethanol extracts of &lt;em&gt;Enhalus acoroides&lt;/em&gt; (IC&lt;sub&gt;50&lt;/sub&gt; values 168.15 &amp;plusmn; 2.71 &lt;em&gt;&amp;mu;&lt;/em&gt;g/mL) had the most potential &amp;alpha;-glucosidase inhibitors activity compared with the positive control acarbose, &lt;em&gt;Thalassia hemprichii&lt;/em&gt; and &lt;em&gt;Cymodocea rotundata&lt;/em&gt; (IC&lt;sub&gt;50&lt;/sub&gt; values 197.27 &amp;plusmn; 3.07 &lt;em&gt;&amp;mu;&lt;/em&gt;g/mL, 425.86 &amp;plusmn; 5.15 &lt;em&gt;&amp;mu;&lt;/em&gt;g/mL and 429.28 &amp;plusmn; 8.89 &lt;em&gt;&amp;mu;&lt;/em&gt;g/mL). The kinetic type of inhibition against &amp;alpha;-glucosidase was noncompetitive inhibition. The phytochemical compounds were phenols, flavonoid, terpenes, and tannin with the total phenolic content was 28.76 &amp;plusmn; 2.46 mgGAE/g. &lt;strong&gt;Conclusion:&lt;/strong&gt; &lt;em&gt;Enhalus acoroides&lt;/em&gt; has the strongest inhibitor of &amp;alpha;-glucosidase and can be further developed for DM therapy agents.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">907</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Agung Widiyanto&lt;sup&gt;1&lt;/sup&gt;, Effionora Anwar&lt;sup&gt;1*&lt;/sup&gt;, Tati Nurhayat&lt;sup&gt;i2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, University of Indonesia, Depok 16424, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Aquatic Products Technology, Bogor Agricultural University, Bogor 16680, INDONESIA.&lt;/p&gt;</style></auth-address></record></records></xml>