<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Devi Indriani</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Arikadia Noviani</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Arginase Inhibitory Activity and Total Flavonoid Content on Caesalpinia ferrea C. Mart Stem Bark Extracts</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Arginase</style></keyword><keyword><style  face="normal" font="default" size="100%">Caesalpinia ferrea C. Mart</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoids</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">1180-1183</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Flavonoids, polyphenolic compounds that are ubiquitous in nature, have been known for their pharmacological as antifungal, diuretic, antihistamin, antihypertension, insecticide, bactericide, antiviral, antioxidant, and enzim inhibitor. Flavanones found in all parts &lt;em&gt;Scutellaria indica&lt;/em&gt;, has the ability to inhibit arginase, flavanols found in the seeds of &lt;em&gt;Theobroma cacao&lt;/em&gt; L. Previous study showed that &lt;em&gt;Caesalpinia ferrea&lt;/em&gt; C. Mart stem bark contains flavonoid compound.&lt;strong&gt; Objective:&lt;/strong&gt; The objective of this study to analyze arginase inhibitory activity and to determine the total flavonoid content of &lt;em&gt;Caesalpinia ferrea&lt;/em&gt; C. Mart stem bark by using AlCl&lt;sub&gt;3&lt;/sub&gt; colorimetric method. &lt;strong&gt;Methods:&lt;/strong&gt; &lt;em&gt;Dried Caesalpinia&lt;/em&gt; ferrea stem barks were refluxed with three different solvent with gradual gradient polarity i.en-hexane, ethyl acetate, and methanol. Each extract was tested to determine arginase inhibitory activity. Total flavonoid content was determined on extract showed the highest arginase inhibitory activity. &lt;strong&gt;Results:&lt;/strong&gt; Methanolic extract showed arginase inhibitory activity of 12.81% and flavonoid content was 2 mgQE/g. Phytochemical screening on &lt;em&gt;Caesalpinia ferrea&lt;/em&gt; stem bark ethyl acetate extract showed that it contains flavonoids, tannins, saponins, steroids, and terpenoids, meanwhile &lt;em&gt;Caesalpinia ferrea&lt;/em&gt; stem bark methanolic extract contains flavonoids, tannins, saponins, and steroids. Conclusion: &lt;em&gt;Caesalpinia ferrea&lt;/em&gt; C. Mart stem bark extracts were not potential to inhibit arginase.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1180</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Devi Indriani, Berna Elya*, Arikadia Noviani &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacognosy- Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok 16424 West Java, INDONESIA.&lt;/p&gt;</style></auth-address></record></records></xml>