<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sangeetha DN</style></author><author><style face="normal" font="default" size="100%">S. Rajamani</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">In vitro Antidiabetic Activity of Methanolic Leaf Extract of Indianthus virgatus (Roxb.) Suksathan and Borchs by Glucose Uptake Method</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antidiabetic activity</style></keyword><keyword><style  face="normal" font="default" size="100%">In vitro cytotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Indianthus virgatus (Roxb.) Suksathan and Borchs</style></keyword><keyword><style  face="normal" font="default" size="100%">L-6 cell line</style></keyword><keyword><style  face="normal" font="default" size="100%">Methanolic leaf extract</style></keyword><keyword><style  face="normal" font="default" size="100%">MTT Assay</style></keyword><keyword><style  face="normal" font="default" size="100%">Skeletal muscle Cell Lines</style></keyword><keyword><style  face="normal" font="default" size="100%">Therapeutic agents</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">674-677</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Medicinal plants play a key role to cure many diseases from time immemorial. The usage of medicinal plants in traditional medicinal system is the vital process of India. Diabetes Mellitus is a systemic metabolic disease characterized by hyperglycemia, abnormal elevated levels of lipid and fat in blood and hypoinsulinaemia. The current epidemic of diabetes indicates the need of proper and effective medications that are limited in their potency to have many side effects. Thus, introduction of alternative and complementary medicine is now in picture. &lt;strong&gt;Objective:&lt;/strong&gt; The main objective of this work is to evaluate the &lt;em&gt;in vitro&lt;/em&gt; anti diabetic activity of methanolic extracts of &lt;em&gt;Indianthus virgatus&lt;/em&gt; (Roxb.) Suksathan and Borchs in skeletal muscle cell line. &lt;strong&gt;Methods:&lt;/strong&gt; The &lt;em&gt;in vitro &lt;/em&gt;cytotoxicity was performed for leaf extract (Methanol) on L-6 (Rat skeletal muscle) cell line to find toxic concentration of the leaf extract by MTT assay. Glucose uptake activity of test substance was determined in differentiated L-6 cells. &lt;strong&gt;Results:&lt;/strong&gt; In Glucose uptake assay, Methanol Extract exhibited moderate toxicity to skeletal muscle cell line and glucose uptake assay it shows dose dependent glucose uptake. Glucose uptake rate increased with the increasing concentration of the leaf extract. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results of the current study clearly demonstrated the antidiabetic potency of methanolic leaf extract obtained from &lt;em&gt;Indianthus virgatus &lt;/em&gt;(Roxb.) Suksathan and Borchs. under &lt;em&gt;in vitro &lt;/em&gt;model.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">674</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sangeetha DN&lt;sup&gt;1,&lt;/sup&gt;*, S. Rajamani&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Research Scholar, Bharathiar University, Coimbatore, Tamil Nadu, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Associate Professor, Department of Botany, St. Josephs’ Post Graduate and Research Centre, Bengaluru, Karnataka, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sangeetha D N</style></author><author><style face="normal" font="default" size="100%">S Rajamani</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">In-vitro Cytotoxic Activity of Indianthus virgatus (Roxb.)Suksathan and Borchs. On A549, A431, CaCo2, U87 and L929 Cell Lines</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anticancer activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Cancer Cell Lines</style></keyword><keyword><style  face="normal" font="default" size="100%">Indianthus virgatus (Roxb.) Suksathan and Borchs</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plant</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">1216-1220</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Medicinal plants play a key role to cure many diseases from time immemorial. The usage of medicinal plants in traditional medicinal system is the vital process of India. Cancer is one of the killing diseases and causes severe defects on human being. There are many types of cancer diseases in human beings affects the different organs. There is no proper medicine to cure such kind of cancer diseases. &lt;strong&gt;Objective:&lt;/strong&gt; The purpose of the study is to evaluate the test substances for their cytotoxicity against selected cell lines.&lt;strong&gt; Methods:&lt;/strong&gt; In the present study the&lt;em&gt; in-vitro&lt;/em&gt; cytotoxicity potential of chloroform and methanolic leaf extract of &lt;em&gt;Indianthus virgatus&lt;/em&gt; (Roxb.) Suksathan and Borchs. Was carried out against five cell lines, four of which were cancerous and one normal cell line i.e., A549, A431, CaCo2, U87 and L929. &lt;strong&gt;Results:&lt;/strong&gt; The results revealed that the cytotoxicity potential of the leaf and rhizome increased with the increase in concentration of leaf and rhizome extracts. The chloroform leaf extract showed highest percentage of growth inhibition against A549 cell line. The methanol leaf extract showed highest percentage of growth inhibition against A431 cell line. The chloroform leaf extract showed highest percentage of growth inhibition against CaCo2 cell line. The chloroform rhizome extract showed highest percentage of growth inhibition against U87 cell line. The methanolic leaf extract showed highest percentage of growth inhibition against L929 cell line .This shows that for different cell lines the highest percentage growth of inhibition was shown by different extracts. &lt;strong&gt;Conclusion:&lt;/strong&gt; The present study has suggested that the leaf and rhizome extracts of&lt;em&gt; Indianthus virgatus&lt;/em&gt; (Roxb.) Suksathan and Borchs. , Possesses potent anticancer property which can be used to prepare anticancer drug with proper standardization methods.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1216</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sangeetha D N&lt;sup&gt;1,&lt;/sup&gt; S. Rajamani&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Botany, Research Scholar, Bharathair University, Coimbatore, Tamil Nadu INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Botany, Associate Professor St. Joseph&amp;rsquo;s Post Graduate and Research Centre, Langford road, Bengaluru, Karnataka, INDIA.&lt;/p&gt;</style></auth-address></record></records></xml>