<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Fidan Suleymanova</style></author><author><style face="normal" font="default" size="100%">Olga Nesterova</style></author><author><style face="normal" font="default" size="100%">Alexey Matyushin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">HPLC Quantification of Hydroxycinnamic and Organic Acids of Canadian Goldenrod (Solidago canadensis L.)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Canadian goldenrod</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydroxycinnamic acids</style></keyword><keyword><style  face="normal" font="default" size="100%">Organic acids</style></keyword><keyword><style  face="normal" font="default" size="100%">Solidago canadensis</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">400-404</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;strong&gt;Background&lt;/strong&gt;: Canadian goldenrod (&lt;em&gt;Solidago canadensis&lt;/em&gt; L.) is a medicinal plant widely used in traditional medicine across the world for several hundred years. According to literature data, &lt;em&gt;S. canadensis&lt;/em&gt; contains various groups of biologically active substances, including tannins, flavonoids, etc. The aim of the study was to identify and quantify hydroxycinnamic and organic acids in aerial parts of Canadian goldenrod, as these groups of substances demonstrate a broad spectrum of therapeutic activities. &lt;strong&gt;Materials and Methods&lt;/strong&gt;: Ethanolic extracts of &lt;em&gt;S. canadensis&lt;/em&gt;, gathered in Central Russia, were analyzed using highperformance liquid chromatography (HPLC). Hydroxycinnamic acids (HCA) determination was carried out by HPLC method with UV detection at 330 nm using HCA reference standards (RS). Organic acids (OA) determination was performed in the same manner, utilizing UV detection at 210 nm and corresponding OA RS. &lt;strong&gt;Results&lt;/strong&gt;: It was established that &lt;em&gt;S. canadensis&lt;/em&gt; HCA composition is represented by cichoric, caffeic, chlorogenic, quinic and ferulic acids. The total HCA content in was 1.16 g ± 10.7 mg / 100 g. Main OA, found in &lt;em&gt;S. canadensis&lt;/em&gt;, are ascorbic, citric, tartaric, succinic, gallic, malic, oxalic and fumaric acids, with the total OA content of 426.5 mg ± 6.4 mg / 100 g. &lt;strong&gt;Conclusion&lt;/strong&gt;: The described HPLC method was successfully used for analysis of &lt;em&gt;S. canadensis&lt;/em&gt; aerial parts ethanolic extracts. The method can be utilized for HCA and OA identification and quantification in both herbal raw material and herbal medicinal products containing Canadian goldenrod.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">400</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Fidan Suleymanova&lt;sup&gt;1,&lt;/sup&gt;*, Olga Nesterova&lt;sup&gt;1&lt;/sup&gt;, Alexey Matyushin&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Chemistry, Institute of Pharmacy, Sechenov First Moscow State Medical University, 119991 Moscow, RUSSIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Analytical Toxicology, Pharmaceutical Chemistry and Pharmacognosy, Institute of Pharmacy, Sechenov First Moscow State Medical University, 119991 Moscow, RUSSIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ekaterina Vyacheslavovna Sergunova</style></author><author><style face="normal" font="default" size="100%">Alla Anatolyevna Sorokina</style></author><author><style face="normal" font="default" size="100%">Dmitry Olegovich Bokov</style></author><author><style face="normal" font="default" size="100%">Anna Igorevna Marakhova</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Qualitative and Quantitative Determination of Organic Acids in Crude Herbal Drugs and Medicinal Herbal Preparations for Quality Control in Russian Federation by Modern Physicochemical Methods</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Coulometry</style></keyword><keyword><style  face="normal" font="default" size="100%">Crude herbal drugs</style></keyword><keyword><style  face="normal" font="default" size="100%">High Performance Liquid Chromatography</style></keyword><keyword><style  face="normal" font="default" size="100%">Organic acids</style></keyword><keyword><style  face="normal" font="default" size="100%">Potentiometry</style></keyword><keyword><style  face="normal" font="default" size="100%">Redox titration</style></keyword><keyword><style  face="normal" font="default" size="100%">Titrimetric Methods</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1132-1137</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Organic acids (malic, citric, tartaric, oxalic, acetic, formic, isovaleric, ascorbic acids) make up a large group of biologically active substances and play an important role in plant and human metabolism. They are found in large quantities in the fruits of &lt;em&gt;Rosaceae&lt;/em&gt; family medicinal plants that included in State Pharmacopoeia of the Russian Federation. Standardization of crude herbal drugs containing organic acids by modern physicochemical methods is a high-priority task.&lt;strong&gt; Materials and Methods: &lt;/strong&gt;The determination of total organic acids amount was carried out in aqueous extracts from different fruits of &lt;em&gt;Rosaceae&lt;/em&gt; family plants by galvanostatic coulometry and potentiometry methods. Galvanostatic coulometry was performed with the help of the “Expert-006” coulometer with a current of 5 mA (integrated pH meter). Iodine as an electrogenerated titrant was used for ascorbic acid determination; electro generation of hydroxide ions was carried out for determination of total organic acids amount. A potentiometer “Aquilon pH-410” with attached glass and silver chloride electrodes was used for potentiometric determination of total organic acids amount. Individual organic acids have been determined by reverse-phase high-performance liquid chromatography with ultra-violet detection (RP-HPLCUV) method. The following conditions were established: Gilson HPLC system, Alltech OA- 1000 Organic Acids (6.5×300 mm, 9 μm) chromatography column, a gradient elution mode, component A of the mobile phase is 98% (0.1% phosphoric acid, 10 mM KH&lt;sub&gt;2&lt;/sub&gt;PO&lt;sub&gt;4&lt;/sub&gt;, solution in water) with 2% acetonitrile, component B is acetonitrile, the eluent feed rate is 1 ml/min.&lt;strong&gt; Results: &lt;/strong&gt;Modern physicochemical methods for the analysis of biologically active substances, organic acids, for quality control of crude herbal drugs and medicinal herbal preparations, are developed and discussed. The optimal conditions for the qualitative and quantitative organic acid analysis are selected and described taking into account modern pharmacopoeial requirements. &lt;strong&gt;Conclusion: &lt;/strong&gt;Galvanostatic coulometry and potentiometry methods, as well as RP-HPLC-UV, can be successfully used in the quality control of crude herbal drugs and medicinal herbal preparations, specifically fruits of &lt;em&gt;Rosaceae&lt;/em&gt; family plants. Development and validation of analytical methods for monitoring the content of this BAS group is an important research area in the pharmacopoeial standardization of crude herbal drugs.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1132</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ekaterina Vyacheslavovna Sergunova&lt;sup&gt;1,&lt;/sup&gt;*, Alla Anatolyevna Sorokina&lt;sup&gt;1&lt;/sup&gt;, Dmitry Olegovich Bokov&lt;sup&gt;1,2,3&lt;/sup&gt;, Anna Igorevna Marakhova&lt;sup&gt;4&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical and Natural Sciences, Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, 119991, RUSSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Analytical, Physical and Colloid Chemistry, Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, 119991, RUSSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Laboratory of Food Chemistry, Federal Research Center for Nutrition, Biotechnology and Food Safety, 2/14, Ustyinsky pr., Moscow, 109240, RUSSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Institute of Biochemical Technology and Nanotechnology, Рeoples’ Friendship University of Russia (RUDN University), Miklukho-Maklaya St., 6, Moscow, 117198, RUSSIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ekaterina Vyacheslavovna Sergunova</style></author><author><style face="normal" font="default" size="100%">Dmitry Olegovich Bokov</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Some Pharmacognostic Studies of the Bird Cherry (Padus avium Mill.) and Mountain Ash (Sorbus aucuparia L.) Fruits Collected from Moscow (Russia)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anatomical Signs</style></keyword><keyword><style  face="normal" font="default" size="100%">Fruits</style></keyword><keyword><style  face="normal" font="default" size="100%">Mineral Composition</style></keyword><keyword><style  face="normal" font="default" size="100%">Organic acids</style></keyword><keyword><style  face="normal" font="default" size="100%">Padus avium Mill.</style></keyword><keyword><style  face="normal" font="default" size="100%">Rosaceae</style></keyword><keyword><style  face="normal" font="default" size="100%">Simple Sugars</style></keyword><keyword><style  face="normal" font="default" size="100%">Sorbus aucuparia L.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">996-1002</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Light microscopic analysis is appropriate pharmacopoeial method for quality control of fresh and fast-frozen Rosaceae family plants fruits. It is widely used for crude herbal drugs analysis and helps to identify significant anatomical and diagnostic signs. The aim of the research was to establish the identity characteristics of the dried and frozen fruits of mountain ash and bird cherry and to perform phytochemical analysis of studied objects harvested in Moscow. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Light microscopic analysis was used for Rosaceae fruits identity estimation. The fruits of mountain ash (&lt;em&gt;Sorbus aucuparia&lt;/em&gt; L.) and bird cherry &lt;em&gt;(Padus avium Mill&lt;/em&gt;.) were collected in the fruiting phase on the territory of the Botanical Garden of Sechenov First Moscow State Medical University. Fruits samples were dried at the temperature of 60-80°C and frozen at the temperature of -18-20°C. The epidermis surface preparation and the fruit pulp squash preparation were prepared for microscopic examination. The photographs were obtained from an AXIO IMAGER D1 biological laboratory microscope (Carl Zeiss Microscopy) with the help of a Canon Power shot A 650 IS camera. The elemental composition of the&lt;em&gt; P. avium&lt;/em&gt; and &lt;em&gt;S. aucuparia&lt;/em&gt; fruits was determined by X-ray fluorescence analysis (XFA) using an S4 Pioneer X-ray spectrometer. Simple sugar analysis was performed by using reverse phase HPLC with refractometric detection, analysis of organic acids – by using ion-pair HPLC with UV-detection (210 nm) in the isocratic elution mode (Agilent 1260 Infinity LC). &lt;strong&gt;Results: &lt;/strong&gt;Characteristic signs of the anatomical structure of dried and frozen &lt;em&gt;S. aucuparia, P. avium&lt;/em&gt; fruits were determined. Diagnostic anatomical signs of &lt;em&gt;S. aucuparia, P. avium&lt;/em&gt; fruits are: the form of epidermal cells, stone cells, inclusions of calcium oxalate (prismatic crystals and druses), vessels, parenchyma with biologically active substances (anthocyanins, carotenoids). The presence and content of Na, Mg, Al, Si, P, S, K, Ca, Ti, Cr, Mn, Fe, Ni, Cu, Zn, Rb, Sr were evaluated. Organic acids profile of&lt;em&gt; S. aucuparia, P. avium&lt;/em&gt; fruits is presented by citric, malic, oxalic, succinic, tartaric, fumaric, quinic, ascorbic, sorbic acids. Total content of simple sugars, presented by glucose, fructose, sucrose, is in the interval of 8-9%.&lt;strong&gt; Conclusion: &lt;/strong&gt;The results of a comparative microscopic analysis of bird cherry and mountain ash dried and frozen fruits were obtained. They allowed to identify diagnostically significant elements of the anatomical structure that can be used to establish the fruits identity. The obtained data is of great value for &lt;em&gt;S. aucuparia, P. avium&lt;/em&gt; fruits pharmacopoeial analysis in the Russian Federation.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">996</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ekaterina Vyacheslavovna Sergunova&lt;sup&gt;1,&lt;/sup&gt;*, Dmitry Olegovich Bokov&lt;sup&gt;1,2,3&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical and Natural Sciences, Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, Moscow, 119991, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Analytical, Physical and Colloid Chemistry, Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, Moscow, 119991, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Laboratory of Food Chemistry, Federal Research Center for Nutrition, Biotechnology and Food Safety, 2/14, Ustyinsky pr., Moscow, 109240, RUSSIAN FEDERATION.&lt;/p&gt;
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