<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yufri Aldi</style></author><author><style face="normal" font="default" size="100%">Dwisari Dillasamola</style></author><author><style face="normal" font="default" size="100%">Gita Rahma Yanti</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Immunomodulator Activity of Ethanol Extract of Tapak Liman Leaves (Elephantopus scaber Linn.)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Carbon clearance</style></keyword><keyword><style  face="normal" font="default" size="100%">Elephantopus scaber Linn.</style></keyword><keyword><style  face="normal" font="default" size="100%">Immunomodulator</style></keyword><keyword><style  face="normal" font="default" size="100%">Leucocytes</style></keyword><keyword><style  face="normal" font="default" size="100%">Lymph</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1419-1427</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Tapak Liman (&lt;em&gt;Elephantopus scaber&lt;/em&gt; Linn) is a medicinal plant in Indonesia which traditionally used as a treatment for fever, gout, dysentery, hepatitis, and infections.&lt;strong&gt; Aim:&lt;/strong&gt; This study aims to determine the immunostimulants activity of tapak liman extract with carbon clearance method and to determine the percentage and total leukocytes and relative lymph weights.&lt;strong&gt; Materials and Methods:&lt;/strong&gt; Twenty white male mice divide assigned to 1 control group and 3 experimental groups. It treated by oral administration of tapak liman extract; 10, 30, and 100 mg/kgBW. After six days of administration, mice intravenously injected with 0.1 ml/10gBW colloidal carbon. Blood obtained from the mice tail at; 3rd, 6th, 9th, 12th and 15th minutes. The determined absorbance then calculated to obtain the phagocytotic index, the percentage and the total of leukocyte cells and lymph weights. &lt;strong&gt;Results: &lt;/strong&gt;Phagocytosis index increased significantly at 1, 12, 1.24 and 1.47. The percentages of neutrophil segment are 57%, 60% and 60%, for lymphocytes are 3, 80%, 32.80% and 34.20%, monocyte cells are 4.60%, 3.00% and 2.60%, neutrophil are 3.40%, 3.20%,2.20%, and for the eosinophil cells are 3.20%, 1.8% and 1.20%. Total leukocyte cells are 10,760, 11,630 and 15,880 cells/microliter. The relative lymph weight of each dose in the sequence is 0.36, 0.49 and 0.66. &lt;strong&gt;Conclusion: &lt;/strong&gt;Ethanol extract of tapak liman leaves (&lt;em&gt;Elephantopus scaber&lt;/em&gt; Linn) can increase the immunity of mice.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1419</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Yufri Aldi*, Dwisari Dillasamola, Gita Rahma Yanti &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, Department of Pharmacology, Universitas Andalas, Padang, INDONESIA.&lt;/p&gt;
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