<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Towseef Hassan</style></author><author><style face="normal" font="default" size="100%">Elanchezhiyan C</style></author><author><style face="normal" font="default" size="100%">Insha Naseer</style></author><author><style face="normal" font="default" size="100%">S Marimuthu</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of Perillyl Alcohol (POH) A Monoterpene on Lipid Peroxidation and Antioxidant Status in High Fat Diet-Low Dose STZ Induced Type 2 Diabetes in Experimental Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidants</style></keyword><keyword><style  face="normal" font="default" size="100%">High Fat Diet</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipid peroxidation</style></keyword><keyword><style  face="normal" font="default" size="100%">Perillyl alcohol</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1434-1441</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Aim:&lt;/strong&gt; The plan of this study was to assess the protective activity of Perillyl alcohol (POH) on the levels of lipid peroxidation (LPO) by-products and antioxidant defense systems in the plasma and other tissues of normal and High Fat Diet-Low Dose Streptozotocin (STZ) induced type 2 diabetes in wistar rats. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; The experimental diabetes was induced in animals by High Fat Diet-Low Dose STZ (35 mg/kg i.p.) injection, and treatment with Perillyl alcohol at the dose of (50mg/kg b.w and 100mg/kg b.w) was continued for 30 days. At the end of treatment period, oxidative stress parameters like lipid peroxidation by-products; enzymatic antioxidants such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and non-enzymic antioxidants including reduced glutathione, Vitamin C and Vitamin E were measured in the plasma and tissues of experimental rats. &lt;strong&gt;Results:&lt;/strong&gt; In untreated diabetic rats an increase was seen in the levels of lipid peroxidation by-products and significant decrease was seen in antioxidant enzymes. Oral administration of Perillyl alcohol a monocyclic monoterpene to diabetic rats for 30 days caused a significant reduction in the levels of lipid peroxidation by-products and an increase in the activities of antioxidant enzymes, when the same were compared with the untreated diabetic group. &lt;strong&gt;Conclusion:&lt;/strong&gt; The result of this study indicates that Perillyl alcohol has anti lipid peroxidation and antioxidant status potential in experimental diabetes.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1434</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Towseef Hassan, Elanchezhiyan C*, Insha Naseer, S. Marimuthu&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Zoology, Annamalai University, Annamalainagar, Chidambaram-608002, Tamil Nadu, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">D. Sathis Kumar,</style></author><author><style face="normal" font="default" size="100%">David Banji,</style></author><author><style face="normal" font="default" size="100%">A. Harani,</style></author><author><style face="normal" font="default" size="100%">Ch. Pavan Kumar,</style></author><author><style face="normal" font="default" size="100%">JN. Ravi Varma</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Role of Boswellia ovalifoliolata Bal. Henry extract on high fat diet induced hypercholesterolemia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Boswellia Ovalifoliolata Bal. Henry</style></keyword><keyword><style  face="normal" font="default" size="100%">High Fat Diet</style></keyword><keyword><style  face="normal" font="default" size="100%">lipid profile</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">8th April 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">108-116</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; To evaluate the Antihypercholesterolemic effect of &lt;em&gt;Boswellia ovalifoliolata&lt;/em&gt; Bal. Henry extract by performing &lt;em&gt;in vivo&lt;/em&gt; studies and to check out its effects by evaluating parameters like food consumption, weight gain, fecal fat excretion, serum and liver lipid &amp;amp;biochemical profiles. Even the study includes confirmation of activity by the histopathological studies. &lt;strong&gt;Methods: &lt;/strong&gt;Animals were fed with cholesterol rich high fat diet. Food intake, Body weight and fecal fat excretion were measured. Serum and liver samples were analyzed for the estimation of lipid profiles and other biochemical parameters by using different kits. Histopathological study on liver, aorta, heart and adipose tissue was done to ensure the activity.&lt;strong&gt; Results:&lt;/strong&gt; The animal group administered with methanolic extract of the plant has shown decreased levels of TC, LDL, VLDL, TG, HDL+VLDL, VLDL+LDL, LDL/TC, AI, SGOT, SGPT and elevated levels of HDL, HDL/TC in a dose dependent manner significantly (p&amp;lt;0.01 &amp;amp; p&amp;lt;0.05). The evaluation of liver tissue of animal groups treated with herbal extract and standard had shown increased levels of SOD, GSH and Catalase, whereas levels of SGOT, SGPT, Total glucose, HMG-CoA, lipase, amylase and percentage of monaldehyde were decreased when compared with high fat diet fed rats. Body weight and Food intake in treated groups were significantly lower than that in model control. &lt;strong&gt;Conclusion:&lt;/strong&gt; It can be confered from the present studies that the &lt;em&gt;Boswellia ovalifoliolata&lt;/em&gt; Bal. Henry extract have strong activity against hypercholesterolemia and obesity suggesting a potential benefit as antihypercholesterolemic agent.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;key words&lt;/strong&gt;: &lt;em&gt;Boswellia ovalifoliolata&lt;/em&gt; Bal. Henry, High fat diet, Lipid profile, Histopathological studies.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;D. Sathis Kumar&lt;sup&gt;1,2*&lt;/sup&gt;, David Banji&lt;sup&gt;3&lt;/sup&gt;, A. Harani&lt;sup&gt;4&lt;/sup&gt;, Ch. Pavan Kumar&lt;sup&gt;1&lt;/sup&gt; and JN. Ravi Varma&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;4&lt;/strong&gt;&lt;/sup&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Aditya Institute of Pharmaceutical Sciences and Research, Surampalem, Andhra Pradesh, India-533437&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Jawaharlal Nehru Technical University, Hyderabad, Andhra Pradesh, India&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh, India-508001&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;A.U. College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, India-530003.&lt;/p&gt;</style></auth-address></record></records></xml>