<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Towseef Hassan</style></author><author><style face="normal" font="default" size="100%">Elanchezhiyan C</style></author><author><style face="normal" font="default" size="100%">Insha Naseer</style></author><author><style face="normal" font="default" size="100%">S Marimuthu</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of Perillyl Alcohol (POH) A Monoterpene on Lipid Peroxidation and Antioxidant Status in High Fat Diet-Low Dose STZ Induced Type 2 Diabetes in Experimental Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidants</style></keyword><keyword><style  face="normal" font="default" size="100%">High Fat Diet</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipid peroxidation</style></keyword><keyword><style  face="normal" font="default" size="100%">Perillyl alcohol</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1434-1441</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Aim:&lt;/strong&gt; The plan of this study was to assess the protective activity of Perillyl alcohol (POH) on the levels of lipid peroxidation (LPO) by-products and antioxidant defense systems in the plasma and other tissues of normal and High Fat Diet-Low Dose Streptozotocin (STZ) induced type 2 diabetes in wistar rats. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; The experimental diabetes was induced in animals by High Fat Diet-Low Dose STZ (35 mg/kg i.p.) injection, and treatment with Perillyl alcohol at the dose of (50mg/kg b.w and 100mg/kg b.w) was continued for 30 days. At the end of treatment period, oxidative stress parameters like lipid peroxidation by-products; enzymatic antioxidants such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and non-enzymic antioxidants including reduced glutathione, Vitamin C and Vitamin E were measured in the plasma and tissues of experimental rats. &lt;strong&gt;Results:&lt;/strong&gt; In untreated diabetic rats an increase was seen in the levels of lipid peroxidation by-products and significant decrease was seen in antioxidant enzymes. Oral administration of Perillyl alcohol a monocyclic monoterpene to diabetic rats for 30 days caused a significant reduction in the levels of lipid peroxidation by-products and an increase in the activities of antioxidant enzymes, when the same were compared with the untreated diabetic group. &lt;strong&gt;Conclusion:&lt;/strong&gt; The result of this study indicates that Perillyl alcohol has anti lipid peroxidation and antioxidant status potential in experimental diabetes.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1434</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Towseef Hassan, Elanchezhiyan C*, Insha Naseer, S. Marimuthu&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Zoology, Annamalai University, Annamalainagar, Chidambaram-608002, Tamil Nadu, INDIA.&lt;/p&gt;
</style></auth-address></record></records></xml>