<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yufri Aldi</style></author><author><style face="normal" font="default" size="100%">Elidahanum Husni</style></author><author><style face="normal" font="default" size="100%">Relin Yesika</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Activity of Kincung Flowers (Etlingera Elatior (Jack) R.M.Sm.) on Total Leukocytes and Percentage of Leukocytes in Allergic Male White Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Allergies</style></keyword><keyword><style  face="normal" font="default" size="100%">Etlingera elatior (Jack) R.M.Sm</style></keyword><keyword><style  face="normal" font="default" size="100%">Kincung Flower</style></keyword><keyword><style  face="normal" font="default" size="100%">Leukocyte Percentage</style></keyword><keyword><style  face="normal" font="default" size="100%">Mice</style></keyword><keyword><style  face="normal" font="default" size="100%">Total Leukocytes</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February  2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">44-51</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Kincung Flower (&lt;em&gt;Etlingera elatior &lt;/em&gt;(Jack) R.M.Sm.) is a native herbal plant in Southeast Asia that traditionally used to many diseases, especially in Indonesia. &lt;strong&gt;Aim: &lt;/strong&gt;This study was conducted to determine the activity of kincung (&lt;em&gt;Etlingera elatior&lt;/em&gt; (Jack) R.M.Sm.) on the total number of leukocytes and differential leukocyte cells in allergic mice.&lt;strong&gt; Material and Methods:&lt;/strong&gt; The semi-solid extract of Kincung flower (&lt;em&gt;Etlingera elatior &lt;/em&gt;(Jack) R.M.Sm.) was made by the maceration method using 70% ethanol solvent. The animals used were 20 male white mice that have allergies of skin that treated with 20% albumen antigens given on the first day 0.2 mL/20 g intraperitoneally, then on the seventh day are given antigens with the same dose subcutaneously. Allergic mice indicated by redness at the injection site. It divided into four groups: the negative control group and three dose groups (100; 300; and 1000 mg/kg). On the seventh day after administration of the extract, observed the value of total leukocytes and differential leukocyte cells in mice. &lt;strong&gt;Results:&lt;/strong&gt; The results after administration of extracts in 3 dose groups (100; 300; and 1000 mg / kg) and the negative control group showed sequentially the total number of leukocytes was: 3.95; 4.73; 6.01; and 3.6 x103/μL and the percentage of leukocytes consisting of lymphocytes: 67.6%; 62.0%; 56.8% and 70.0%, neutrophils: 22.4%; 29.2%; 36.8% and 20.0%, eosinophils: 6.4%; 5.8%, 4.2% and 6.6%, monocytes: 3.6%; 3.0%, 2.2% and 3.4%, and basophils: 1.8%; 1.4; 0.8% and 2.0%. It concluded that kincung flowers could increase total leukocytes significantly (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05), decrease lymphocytes, eosinophils, basophils significantly (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05), increase neutrophils significantly (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05), and reduce monocytes insignificantly (&lt;em&gt;p&lt;/em&gt;&amp;gt;0.05). &lt;strong&gt;Conclusion:&lt;/strong&gt; Kincung flowers (&lt;em&gt;Etlingera Elatior&lt;/em&gt; (Jack) R.M.Sm.) can be used as an immunomodulator and decreasing the percentage of basophil cells, and eosinophils can used as an anti-allergic drug.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">44</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Yufri Aldi*, Elidahanum Husni, Relin Yesika &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Pharmacy, University Andalas, INDONESIA.&lt;/p&gt;
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