<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sandile Nduduzo Mboyazi</style></author><author><style face="normal" font="default" size="100%">Mduduzi Innocent Nqotheni</style></author><author><style face="normal" font="default" size="100%">Tsolanku Sidney Maliehe</style></author><author><style face="normal" font="default" size="100%">Jabulani Siyabonga Shandu</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">In vitro Antibacterial and In silico Toxicity Properties of Phytocompounds from Ricinus communis Leaf Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Chemical compounds</style></keyword><keyword><style  face="normal" font="default" size="100%">Ricinus communis</style></keyword><keyword><style  face="normal" font="default" size="100%">Toxicity</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">977-983</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;The rapid occurrence of multiple drug resistance and adverse side effects of aliphatic medicine threatens human health. Medicinal plants are known to possess phytocompounds with antibacterial activity and less toxic effects.&lt;strong&gt; Objective:&lt;/strong&gt; This study aimed at determining the chemical composition of the methanolic&lt;em&gt; Ricinus communis&lt;/em&gt;` leaf extract and evaluate their antibacterial and toxic effects. &lt;strong&gt;Methods:&lt;/strong&gt; &lt;em&gt;R. communis&lt;/em&gt; leaves were extracted by acetone, chloroform, ethanol and methanol. The extracts were assessed for antibacterial activity against &lt;em&gt;Bacillus cereus&lt;/em&gt; (ATCC 10102), &lt;em&gt;Escherichia coli &lt;/em&gt;(25922), &lt;em&gt;Staphylococcus aureus&lt;/em&gt; (25923) and &lt;em&gt;Pseudomonas aeruginosa&lt;/em&gt; (ATCC 27853) using agar-well diffusion and microwell dilution methods. The extracts were screened for alkaloids, flavonoids, saponins, steroids, tannins and terpenoids. The chemical constituents of the methanolic extract were analysed by gas chromatography – mass spectrophotometry (GC-MS). In silico toxicity of the phytocompounds were investigated using PreADMET tool. &lt;strong&gt;Results:&lt;/strong&gt; The methanol extract showed the antibacterial activity against the bacterial strains, with the MIC values of 1.56 mg/mL against &lt;em&gt;B. cereus&lt;/em&gt;, 3.13 mg/mL and 6.25 mg/mL against &lt;em&gt;P. aeruginosa&lt;/em&gt; and &lt;em&gt;E. coli&lt;/em&gt;. The extracts revealed the presence of alkaloids, flavonoids, glycosides, steroids, tannins, terpenoids and saponins. The GC-MS showed phytocompounds namely hexadecanoic acid, methyl ester (0.62%), tridecanoic acid (0.76%), pentafluoropropionic acid, nonyl ester (0.85%), 10-octadecanoic acid, methyl ester (2.93%) and cis-vaccenic acid (94.84%). Hexadecanoic acid, methyl ester was predicted not to have mutagenic and carcinogenic effects. Moreover, all compounds exhibited low inhibitory risks against hERG gene. &lt;strong&gt;Conclusion: &lt;/strong&gt;&lt;em&gt;R. communis &lt;/em&gt;leaf extract has potential to be used as a safe source of therapeutic compounds.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">977</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sandile Nduduzo Mboyazi&lt;sup&gt;1,&lt;/sup&gt;*, Mduduzi Innocent Nqotheni&lt;sup&gt;1&lt;/sup&gt;, Tsolanku Sidney Maliehe&lt;sup&gt;1&lt;/sup&gt;, Jabulani Siyabonga Shandu&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa 3886, SOUTH AFRICA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Bokov DO</style></author><author><style face="normal" font="default" size="100%">Barkalova VE</style></author><author><style face="normal" font="default" size="100%">Suslikova MA</style></author><author><style face="normal" font="default" size="100%">Sokhin DM</style></author><author><style face="normal" font="default" size="100%">Kakhramanova SD</style></author><author><style face="normal" font="default" size="100%">Rendyuk TD</style></author><author><style face="normal" font="default" size="100%">Strelyaeva AV</style></author><author><style face="normal" font="default" size="100%">Antsyshkina AM</style></author><author><style face="normal" font="default" size="100%">Balobanova NP</style></author><author><style face="normal" font="default" size="100%">Prostodusheva TV</style></author><author><style face="normal" font="default" size="100%">Grikh VV</style></author><author><style face="normal" font="default" size="100%">Krasnyuk II1 (junior)</style></author><author><style face="normal" font="default" size="100%">Marakhova AI</style></author><author><style face="normal" font="default" size="100%">Moiseev DV</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Lathraea squamaria L. (Orobanchaceae): A Review of its Botany, Phytochemistry, Traditional Uses and Pharmacology</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Aucubin</style></keyword><keyword><style  face="normal" font="default" size="100%">Chemical compounds</style></keyword><keyword><style  face="normal" font="default" size="100%">Common toothwort</style></keyword><keyword><style  face="normal" font="default" size="100%">Iridoids</style></keyword><keyword><style  face="normal" font="default" size="100%">Lathraea squamaria</style></keyword><keyword><style  face="normal" font="default" size="100%">Orobanchaceae</style></keyword><keyword><style  face="normal" font="default" size="100%">Parasitic plants</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">667-673 </style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;This paper presents the results of the review pharmacognostic study of common toothwort, a perennial plant, parasitizing on the roots of trees. Currently, in Russian traditional medicine, there is considerable experience in the use of сommon toothwort (&lt;em&gt;Lathraea squamaria&lt;/em&gt; L.) herb and roots as antitumoral, biligenic, infertility-treatment and diuretic drugs. The chemical composition of &lt;em&gt;L. squamaria&lt;/em&gt; has not been quite well determined. Phenylethanoid glycosides (acteoside, isoacteoside), iridoid glycosides (aucubin, and aucuboside ester, 6'-O-glucopyranosyl-aucubin, melampyroside, 6'-O-glucopyranosyl melampyroside), simple sugars, fatty acids, organic acids, β-sitosterol were identified. Further study of&lt;em&gt; L. squamaria &lt;/em&gt;raw materials is a very promising field including implementation in official medicine.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">667</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Bokov DO&lt;sup&gt;1,2,#,&lt;/sup&gt;*, Barkalova VE&lt;sup&gt;3,#&lt;/sup&gt;, Suslikova MA&lt;sup&gt;1&lt;/sup&gt;, Sokhin DM&lt;sup&gt;1&lt;/sup&gt;, Kakhramanova SD&lt;sup&gt;1,4&lt;/sup&gt;, Rendyuk TD&lt;sup&gt;1&lt;/sup&gt;, Strelyaeva AV&lt;sup&gt;1&lt;/sup&gt;, Antsyshkina AM&lt;sup&gt;1&lt;/sup&gt;, Balobanova NP&lt;sup&gt;1&lt;/sup&gt;, Prostodusheva TV&lt;sup&gt;1&lt;/sup&gt;, Grikh VV&lt;sup&gt;1&lt;/sup&gt;, Krasnyuk II&lt;sup&gt;1&lt;/sup&gt; (junior), Marakhova AI&lt;sup&gt;5&lt;/sup&gt;, Moiseev DV&lt;sup&gt;6&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Institute of Pharmacy, Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, Moscow, 119991, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of Food Chemistry, Federal Research Center of Nutrition, Biotechnology and Food Safety, 2/14 Ustyinsky pr., Moscow, 109240, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Faculty of Pediatrics, Siberian State Medical University, 2 Moscow tract, 634050, Tomsk, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of State Pharmacopoeia and pharmacopoeia analysis, Federal State Budgetary Institution “Scientific Centre for Expert Evaluation of Medicinal Products”, 8/2 Petrovsky Boulevard, Moscow, 127051, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Pharmaceutical chemistry and pharmacognosy chair, Рeoples’ Friendship University of Russia (RUDN University), 6, Miklukho-Maklaya Street, Moscow, 117198, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Chair of Standardization of Medicines, Vitebsk State Medical University, 27, Frunze avenue, Vitebsk, 210062, BELARUS. #Bokov DO, Barkalova V.E. contributed equally to this work.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gunawan Pasaribu</style></author><author><style face="normal" font="default" size="100%">Emil Budianto</style></author><author><style face="normal" font="default" size="100%">Herry Cahyana</style></author><author><style face="normal" font="default" size="100%">Endang Saepudin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review on Genus Saurauia: Chemical Compounds and their Biological Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Biological activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Chemical compounds</style></keyword><keyword><style  face="normal" font="default" size="100%">Human disease remedy</style></keyword><keyword><style  face="normal" font="default" size="100%">Saurauia</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">657-666</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;&lt;em&gt;Saurauia&lt;/em&gt; plant has been widely used to treat a variety of diseases suffered by villagers at various places in the world. These species are widely used traditionally by the community as antidiabetic and digestive problems’ remedy. This paper will present various uses and researches ever carried out by researchers in the world on various types of the genus &lt;em&gt;Saurauia&lt;/em&gt;.&lt;strong&gt; Methods:&lt;/strong&gt; The Information was collected from scientific journals, books, and reports.&lt;strong&gt; Results: &lt;/strong&gt;This review summarizes the existing information on several species of&lt;em&gt; Saurauia&lt;/em&gt; in relation to their chemical compounds and biological activity. There are some of chemical compounds present and identified in &lt;em&gt;Saurauia&lt;/em&gt;, i.e. 3β-hydroxy-Olean-12-en- 28oic acid; 3,19-Dihydroxyurs-12-en-28-oic acid; 3-hidroksi, 12(13)-en, 28-oleanolat acid; actinidin; several monoterpene lactones; seven triterpenoids, namely, cis-3-O-p-hydroxycinnamoyl ursolic acid; trans-3-O-p-hydroxycinnamoyl ursolic acid; ursolic acid; oleanolic acid; corosolic acid; maslinic acid; and β-amyrin; and two steroids, stigmasterol; and β-sitosterol. There are several biological activities afforded by &lt;em&gt;Saurauia &lt;/em&gt;i.e. antioxidant activity, anti-cholesterol, antidiabetic activity, antihyperlipidemic, analgetic activity, antimicrobial activity, wound-healing activity and immunostimulatory activity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">657</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Gunawan Pasaribu&lt;sup&gt;1,&lt;/sup&gt;*, Emil Budianto&lt;sup&gt;2&lt;/sup&gt;, Herry Cahyana&lt;sup&gt;2&lt;/sup&gt;, Endang Saepudin&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Postgraduated Student at Department of Chemistry, Faculty of Matematics and Natural Sciences, Universitas Indonesia, Depok, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Chemistry, Faculty of Matematics and Natural Sciences, Universitas Indonesia, Depok, INDONESIA.&lt;/p&gt;
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