<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Paul Alan Arkin Alvarado-García</style></author><author><style face="normal" font="default" size="100%">Marilú Roxana Soto-Vásquez</style></author><author><style face="normal" font="default" size="100%">Elda Maritza Rodrigo-Villanueva</style></author><author><style face="normal" font="default" size="100%">José Gilberto Gavidia-Valencia</style></author><author><style face="normal" font="default" size="100%">Natalia Mavila Guzmán Rodríguez</style></author><author><style face="normal" font="default" size="100%">Roger Antonio Rengifo-Penadillos</style></author><author><style face="normal" font="default" size="100%">Julio Víctor Campos-Florián</style></author><author><style face="normal" font="default" size="100%">Yolanda Elizabeth Rodríguez de Guzmán</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Chamomile (Matricaria chamomilla L.) Essential Oil and its Potential Against Stress, Anxiety, and Sleep Quality</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anxiety</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oils</style></keyword><keyword><style  face="normal" font="default" size="100%">Matricaria chamomilla</style></keyword><keyword><style  face="normal" font="default" size="100%">Sleep quality</style></keyword><keyword><style  face="normal" font="default" size="100%">stress</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">100-107</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;This investigation aimed to evaluate the effect of Matricaria chamomilla L essential oil on stress, anxiety, and sleep quality. &lt;strong&gt;Methods:&lt;/strong&gt; The essential oils were extracted by hydrodistillation using a modified Clevenger-type apparatus, and the chemical composition was performed by Gas chromatographymass spectrometry (GC–MS). Furthermore, a study was conducted where 128 participants were divided into two groups: a control group and an experimental group treated with essential oils. Stress, anxiety, and sleep quality were evaluated using the Perceived Stress Scale (PSS–10), the Zung Self-Rating Anxiety Scale (SAS), and the Pittsburgh Sleep Quality Inventory (PSQI). In addition, cortisol was measured.&lt;strong&gt; Results:&lt;/strong&gt; Chemical analysis showed thatα-Bisabolol oxide A exhibited the highest concentration at 30.42%, followed by α -Bisabolol (10.94%), α-Bisabolone oxide A (9.82%), and spathulenol (8.83%). Stress, anxiety, sleep quality, and cortisol scores decreased in the post-test study phase compared to the pre-test in the experimental group (p&amp;lt;0.05). Important effect size was found in the case of anxiety (d = 1.203; Δ = 1.246), while medium effects were observed for stress (d = 0.701; Δ = 0.633) and sleep quality (d = 0.888; Δ = 0.732), while cortisol showed small changes (d=0.374; Δ=0.357). &lt;strong&gt;Conclusion:&lt;/strong&gt; The study showed the potential of Chamomile essential oils to reduce stress and anxiety levels and improve sleep quality.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">100</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Paul Alan Arkin Alvarado- García&lt;sup&gt;1,&lt;/sup&gt;*, Marilú Roxana Soto-Vásquez&lt;sup&gt;2&lt;/sup&gt;, Elda Maritza Rodrigo-Villanueva&lt;sup&gt;2&lt;/sup&gt;, José Gilberto Gavidia-Valencia&lt;sup&gt;2&lt;/sup&gt;, Natalia Mavila Guzmán Rodríguez&lt;sup&gt;3&lt;/sup&gt;, Roger Antonio Rengifo-Penadillos&lt;sup&gt;2&lt;/sup&gt;, Julio Víctor Campos-Florián&lt;sup&gt;2&lt;/sup&gt; , Yolanda Elizabeth Rodríguez de Guzmán&lt;sup&gt;4&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Escuela de Medicina. Universidad César Vallejo, Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Facultad de Farmacia y Bioquímica. Universidad Nacional de Trujillo, Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Escuela de Psicología. Universidad César Vallejo, Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Facultad de Enfermería. Universidad Nacional de Trujillo, Trujillo, Perú.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Paul Alan Arkin Alvarado-García</style></author><author><style face="normal" font="default" size="100%">Marilú Roxana Soto-Vásquez</style></author><author><style face="normal" font="default" size="100%">Luis Enrique Rosales-Cerquin</style></author><author><style face="normal" font="default" size="100%">Santiago M. Benites</style></author><author><style face="normal" font="default" size="100%">Taniht Lisseth Cubas-Romero</style></author><author><style face="normal" font="default" size="100%">Demetrio Rafael Jara-Aguilar</style></author><author><style face="normal" font="default" size="100%">José Gilberto Gavidia-Valencia</style></author><author><style face="normal" font="default" size="100%">Iris Melina Alfaro-Beltrán</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effect of Rosmarinus Officinalis Essential Oil On Anxiety, Depression, And Sleep Quality</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anxiety</style></keyword><keyword><style  face="normal" font="default" size="100%">Depression</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oils</style></keyword><keyword><style  face="normal" font="default" size="100%">Rosmarinus officinalis</style></keyword><keyword><style  face="normal" font="default" size="100%">Sleep quality</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">343-349</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;The objective of this investigation was to evaluate the effect of &lt;em&gt;Rosmarinus officinalis &lt;/em&gt;essential oil on anxiety, depression, and sleep quality. &lt;strong&gt;Methods: &lt;/strong&gt;The essential oils were extracted by hydro-distillation using a modified Clevenger-type apparatus and the chemical composition was performed by Gas chromatography with flame ionization detection (GC-FID) and Gas chromatography mass spectrometry (GC–MS). Furthermore, a quasi-experimental study was conducted, where 81 participants were divided into two groups, comprising a waiting list control group and an experimental group treated with essential oils. Anxiety and depression indexes were evaluated using the Zung Self-Rating Anxiety Scale (SAS) and the Zung Self-Rating Depression Scale (SDS), and sleep quality was measured with the Pittsburgh Sleep Quality Inventory (PSQI). &lt;strong&gt;Results:&lt;/strong&gt; Chemical analysis showed that 1,8 cineole (37.6%), α-pinene (19.9%), and linalool (15.8%) were the main components. Anxiety, depression, and sleep quality scores showed a decrease in the post-test study phase compared to the pre-test in the experimental group (p&amp;lt;0.05). A large size effect was found in the case of anxiety (d = 1.491; g= 1.490) with 1-β=0.996, while medium size effects were observed for depression (d = 0.581; g= 0.582) with 1-β=0.585; and sleep quality (d = 0.586; g = 0.588) with 1-β=0.638. &lt;strong&gt;Conclusion: &lt;/strong&gt;Essential oils extracted from &lt;em&gt;Rosmarinus officinalis&lt;/em&gt; are more effective in calming anxiety and show moderate changes in depression and sleep quality.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">343</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Paul Alan Arkin Alvarado-García&lt;sup&gt;1,*&lt;/sup&gt;, Marilú Roxana Soto-Vásquez&lt;sup&gt;2&lt;/sup&gt;, Luis Enrique Rosales-Cerquin&lt;sup&gt;3&lt;/sup&gt;, Santiago M. Benites&lt;sup&gt;4&lt;/sup&gt;, Taniht Lisseth Cubas- Romero&lt;sup&gt;1&lt;/sup&gt;, Demetrio Rafael Jara- Aguilar&lt;sup&gt;2&lt;/sup&gt;, José Gilberto Gavidia-Valencia&lt;sup&gt;2&lt;/sup&gt;, Iris Melina Alfaro-Beltrán&lt;sup&gt;5&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Escuela de Psicología. Universidad Autónoma del Perú. Lima, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Facultad de Farmacia y Bioquímica. Universidad Nacional de Trujillo, Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Hospital de Apoyo Chepén, Chepén, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Universidad Autónoma del Perú. Lima, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Instituto Pablo Casals, Trujillo, PERÚ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Paul Alan Arkin Alvarado-García</style></author><author><style face="normal" font="default" size="100%">Marilú Roxana Soto-Vásquez</style></author><author><style face="normal" font="default" size="100%">Luis Enrique Rosales-Cerquin</style></author><author><style face="normal" font="default" size="100%">Elda Maritza Rodrigo-Villanueva</style></author><author><style face="normal" font="default" size="100%">Demetrio Rafael Jara-Aguilar</style></author><author><style face="normal" font="default" size="100%">Lurdes Tuesta-Collantes</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anxiolytic and Antidepressant-like Effects of Foeniculum vulgare Essential Oil</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anxiety</style></keyword><keyword><style  face="normal" font="default" size="100%">Depression</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oils</style></keyword><keyword><style  face="normal" font="default" size="100%">Foeniculum vulgare</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">425-431</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction&lt;/strong&gt;: The aim of this research was to determine the anxiolytic and antidepressant-like effects of the essential oils from &lt;em&gt;Foeniculum vulgare &lt;/em&gt;aerial parts and seeds.&lt;strong&gt; Methods&lt;/strong&gt;: The oils were extracted by hydro-distillation using a modified Clevenger-type apparatus and chemical composition was performed by Gas chromatography with flame-ionization detection (GC-FID) and Gas chromatography-mass spectrometry (GC–MS). Furthermore, an experimental trial was conducted, where 117 participants were divided into three groups, comprising a waiting list control group and two experimental groups treated with essential oils. The anxiety and depression indexes were evaluated by Zung Self-Rating Anxiety Scale (SAS) and Zung Self-Rating Depression Scale (SDS). &lt;strong&gt;Results: &lt;/strong&gt;chemical analysis showed that trans- Anethole was the main component, both in the essential oil from aerial parts (35.5%) and seeds (79.2%). Anxiety and depression scores showed a decrease in posttest study phase in comparison with pretest in all experimental groups (p&amp;lt;0.05), except for depression scores in the group treated with essential oil from aerial parts (p&amp;gt;0.05). Small changes were found in the case of anxiety for group treated with essential oils from aerial parts (d = 0.41; Δ= 0.40) while moderate (d = 0.86; Δ = 0.85) and small (d = 0.38; Δ = 0.39) changes were found for anxiety and depression respectively, in the group treated with essential oil from seeds. &lt;strong&gt;Conclusion:&lt;/strong&gt; The essential oil from &lt;em&gt;Foeniculum vulgare&lt;/em&gt; seeds is more effective to relief anxiety than depression while the essential oil from&lt;em&gt; Foeniculum vulgare&lt;/em&gt; aerial parts only exhibit small changes for anxiety.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><section><style face="normal" font="default" size="100%">425</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Paul Alan Arkin Alvarado- García&lt;sup&gt;1,*&lt;/sup&gt;, Marilú Roxana Soto-Vasquez&lt;sup&gt;2&lt;/sup&gt;, Luis Enrique Rosales-Cerquin&lt;sup&gt;1&lt;/sup&gt;, Elda Maritza Rodrigo-Villanueva&lt;sup&gt;2&lt;/sup&gt;, Demetrio Rafael Jara-Aguilar&lt;sup&gt;2&lt;/sup&gt;, Lurdes Tuesta-Collantes&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Escuela de Medicina. Universidad César Vallejo, Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Facultad de Farmacia y Bioquímica. Universidad Nacional de Trujillo, Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Facultad de Ciencias Biológicas. Universidad Nacional de Trujillo, Trujillo, PERÚ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Paul Alan Arkin Alvarado-García</style></author><author><style face="normal" font="default" size="100%">Marilú Roxana Soto-Vásquez</style></author><author><style face="normal" font="default" size="100%">Francisco Mercedes Infantes Gomez</style></author><author><style face="normal" font="default" size="100%">Yolanda Elizabeth Rodríguez de Guzmán</style></author><author><style face="normal" font="default" size="100%">Taniht Lisseth Cubas Romero</style></author><author><style face="normal" font="default" size="100%">Natalia Mavila Guzmán Rodríguez</style></author><author><style face="normal" font="default" size="100%">Olga Gessy Rodríguez Aguilar</style></author><author><style face="normal" font="default" size="100%">Ana María Honores Alvarado</style></author><author><style face="normal" font="default" size="100%">Elsa Rocío Vargas Díaz</style></author><author><style face="normal" font="default" size="100%">Lesly Alexandra Cabrera Cabrera</style></author><author><style face="normal" font="default" size="100%">Klersy Almendra Truyenque Román</style></author><author><style face="normal" font="default" size="100%">Edwar Guido Briceño Esquivel</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Effects of Satureja brevicalyx essential oil inhalation on coping premenstrual syndrome</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anxiety</style></keyword><keyword><style  face="normal" font="default" size="100%">Depression</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oils</style></keyword><keyword><style  face="normal" font="default" size="100%">Premenstrual syndrome</style></keyword><keyword><style  face="normal" font="default" size="100%">Satureja brevicalyx</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">728-735</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;The aim of this research was to evaluate the effects of&lt;em&gt; Satureja brevicalyx&lt;/em&gt; essential oil inhalation on premenstrual syndrome.&lt;strong&gt; Methods:&lt;/strong&gt; The oils were extracted by hydro-distillation using a modified Clevenger-type apparatus and chemical composition was performed by Gas chromatography-mass spectrometry (GC–MS). Furthermore, a quasi-experimental study was conducted, where 61 participants were divided in two groups, comprising an experimental with essential oils and a control group with no treatment. Main psychological symptoms were assessed with the used of Zung Self-Rating Anxiety Scale (SAS) and Zung Self-Rating Depression Scale (SDS) as well as total score of premenstrual syndrome was evaluated with Premenstrual Syndrome Scale (PMSS).&lt;strong&gt; Results:&lt;/strong&gt; chemical analysis showed that linalool (17.6%) was the main component. All variables showed a decrease in posttest study phase in comparison with pretest in experimental group (p&amp;lt;0.05). A large size effect was observed for anxiety (d = 1.25; Δ = 1.35). Besides, moderate changes were found for depression (d = 0.79; Δ= 0.81) and premenstrual syndrome total score (d = 0.62; Δ = 0.56)&lt;strong&gt;. Conclusion: &lt;/strong&gt;The essential oil of&lt;em&gt; Satureja brevicalyx &lt;/em&gt;exerts a potencial use, especially for the treatment of psychological symptoms of premenstrual syndrome.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">728</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Paul Alan Arkin Alvarado-García&lt;sup&gt;1,*&lt;/sup&gt;, Marilú Roxana Soto-Vásquez&lt;sup&gt;2&lt;/sup&gt;, Francisco Mercedes Infantes Gomez&lt;sup&gt;1&lt;/sup&gt;, Yolanda Elizabeth Rodríguez de Guzmán&lt;sup&gt;3&lt;/sup&gt;, Taniht Lisseth Cubas Romero&lt;sup&gt;4&lt;/sup&gt;, Natalia Mavila Guzmán Rodríguez&lt;sup&gt;5&lt;/sup&gt;, Olga Gessy Rodríguez Aguilar&lt;sup&gt;6&lt;/sup&gt;, Ana María Honores Alvarado&lt;sup&gt;6&lt;/sup&gt;, Elsa Rocío Vargas Díaz&lt;sup&gt;6&lt;/sup&gt;, Lesly Alexandra Cabrera Cabrera&lt;sup&gt;1&lt;/sup&gt;, Klersy Almendra Truyenque Román&lt;sup&gt;1&lt;/sup&gt;, Edwar Guido Briceño Esquivel&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Escuela de Medicina. Universidad César Vallejo, Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Facultad de Farmacia y Bioquímica. Universidad Nacional de Trujillo, Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Facultad de Enfermería. Universidad Nacional de Trujillo, Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Universidad Autónoma del Perú, Lima, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Escuela de Psicología. Universidad César Vallejo, Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Escuela de Enfermería. Universidad Privada Antenor Orrego, Trujillo, PERÚ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ramadanil Pitopang</style></author><author><style face="normal" font="default" size="100%">Ihwan</style></author><author><style face="normal" font="default" size="100%">Muhammad Sulaiman Zubair</style></author><author><style face="normal" font="default" size="100%">Nurhaeni</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Essential Oils Constituent of Etlingera flexuosa (Zingiberaceae), An Endemic Plant from Central Sulawesi</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Essential oils</style></keyword><keyword><style  face="normal" font="default" size="100%">Etlingera flexuosa</style></keyword><keyword><style  face="normal" font="default" size="100%">Extraction</style></keyword><keyword><style  face="normal" font="default" size="100%">GC-MS</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydrodistillation</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">842-846</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;The essential oils from rhizomes, pseudostems, and leaves of &lt;em&gt;Etlingera flexuosa,&lt;/em&gt; an endemic ginger species of Sulawesi, were studied.&lt;strong&gt; Methods&lt;/strong&gt;: The essential oils were extracted using solvent extraction and hydrodistillation methods and analysed by gas chromatography-mass spectrometry (GC-MS). &lt;strong&gt;Results:&lt;/strong&gt; The percentage yield of volatile compounds obtained from solvent extraction method was higher than hydrodistillation. By solvent extraction, sesquiterpenes were found abundantly in rhizomes, pseudostems, and leaves with the percentage of 34.16%, 35.20% and 32.70%, respectively. The rhizome and pseudostems were found to contain spathulanol with the high percentage of 3.91% and 3.46%. Meanwhile, by hydrodistillation, the compounds were dominated by fatty acid compunds with the percentage of 82.26%, 82.79% and 76.1% on rhizome, pseudostems and leaves. Glycerol tricaprylate has the high percentage of 66.76% and 82.12% on rhizome and pseudostems, while in leaves, fatty acids 1,2,3-propanetriyl ester-decanoic acid was the highest with the percentage of 61.81%. Sesquiterpenes was the second with the percentage of 10.36%, 11.15%, and 11.61% in rhizomes, pseudostems, and leaves, respectively. &lt;strong&gt;Conclusion:&lt;/strong&gt; The most essential oils of &lt;em&gt;E. flexuosa&lt;/em&gt; was obtained from the solvent extraction method.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><section><style face="normal" font="default" size="100%">842</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ramadanil Pitopang&lt;sup&gt;1&lt;/sup&gt;, Ihwan&lt;sup&gt;2&lt;/sup&gt;, Muhammad Sulaiman Zubair&lt;sup&gt;2&lt;/sup&gt;, Nurhaeni&lt;sup&gt;3,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biology, Faculty of Mathemathics &amp;amp; Natural Sciences, Tadulako University, Palu, Central Sulawesi, 94118, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacy, Faculty of Mathemathics &amp;amp; Natural Sciences, Tadulako University, Palu, Central Sulawesi, 94118, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Chemistry, Faculty of Mathemathics &amp;amp; Natural Sciences, Tadulako University, Palu, Central Sulawesi, 94118, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Asmae Alaoui Belghiti</style></author><author><style face="normal" font="default" size="100%">Mohamed Yafout</style></author><author><style face="normal" font="default" size="100%">Soukaina Bennis</style></author><author><style face="normal" font="default" size="100%">Amal Ait Haj Said</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Survey on Aromatherapy Among Healthcare Professionals in Morocco</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Aromatherapy</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oils</style></keyword><keyword><style  face="normal" font="default" size="100%">Healthcare professionals</style></keyword><keyword><style  face="normal" font="default" size="100%">Morocco</style></keyword><keyword><style  face="normal" font="default" size="100%">Survey</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">666-670</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Herbal remedies and more particularly essential oils are increasingly used throughout the world. In Morocco, the practice of aromatherapy is becoming more and more important, but the knowledge, attitudes, and expectations of healthcare professionals towards essential oils have never been studied. &lt;strong&gt;Aim:&lt;/strong&gt; To assess the attitudes, knowledge, and expectations towards essential oils and aromatherapy of Moroccan healthcare professionals. &lt;strong&gt;Methods: &lt;/strong&gt;We conducted a survey among 205 Moroccan healthcare professionals from different categories using an anonymous electronic questionnaire. &lt;strong&gt;Results:&lt;/strong&gt; The participants to our survey have a good general knowledge and 47.8% of the them have already prescribed or advised essential oils. However, only 10.2% of them considered essential oils as widely available. Moreover, only 3.9% of the respondents judged their theoretical knowledge of essential oils and aromatherapy as perfect, 36.6% considered the lack of information in this field as the limiting factor in prescribing and advising essential oils, and 88.3% were in favor of integrating aromatherapy into their basic training course. The prescription or advice of essential oils are statistically correlated with age, profession, factors mentioned as limiting the prescription and advice of essential oils, and the theoretical knowledge. &lt;strong&gt;Conclusion:&lt;/strong&gt; Empowering healthcare professionals’ capacities could help them overcome their fears and enable them to offer aromatherapy advice to their patients with confidence. This could also help to expand the use of essential oils in Moroccan healthcare facilities.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">666</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Asmae Alaoui Belghiti&lt;sup&gt;1,*&lt;/sup&gt;, Mohamed Yafout&lt;sup&gt;2&lt;/sup&gt;, Soukaina Bennis&lt;sup&gt;3&lt;/sup&gt;, Amal Ait Haj Said&lt;sup&gt;4&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;PhD Student, Laboratory of drug sciences, biomedical research, and biotechnology. Faculty of Medicine and Pharmacy. Hassan II University of Casablanca, MOROCCO.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Resident in industrial pharmacy, Laboratory of drug sciences, biomedical research, and biotechnology. Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, MOROCCO.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Assistant professor of pharmacognosy, Laboratory of drug sciences, biomedical research, and biotechnology. Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, MOROCCO.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Professor of pharmacognosy, Laboratory of drug sciences, biomedical research, and biotechnology. Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, MOROCCO.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Paul Alan Arkin Alvarado-García</style></author><author><style face="normal" font="default" size="100%">Marilú Roxana Soto-Vásquez</style></author><author><style face="normal" font="default" size="100%">Luis Enrique Rosales-Cerquin</style></author><author><style face="normal" font="default" size="100%">Bertha Mirella Alfaro-Ttito</style></author><author><style face="normal" font="default" size="100%">Elda Maritza Rodrigo-Villanueva</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Anxiolytic-like Effect of Essential Oils Extracted from Lippia alba and Lippia citriodora</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anxiety</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oils</style></keyword><keyword><style  face="normal" font="default" size="100%">Lippia alba</style></keyword><keyword><style  face="normal" font="default" size="100%">Lippia citriodora</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1377-1383</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Essential oils from natural plants are widely use around the world to relief mental conditions. The aim of this investigation was to determine the anxiolytic-like effect of essential oils extracted from &lt;em&gt;Lippia alba &lt;/em&gt;and &lt;em&gt;Lippia&lt;/em&gt; citriodora. &lt;strong&gt;Methods&lt;/strong&gt;: The oil was extracted by hydro-distillation for 3 hours using a modified Clevenger-type apparatus and then chemical composition was investigated by gas chromatography analysis (GC) and gas chromatography-mass spectrometry (GC-MS). Moreover, a randomized experimental trial was conducted, where 95 participants were divided into 3 groups, comprising a waiting list control group and two experimental groups treated with essential oils by inhalation. The anxiety index was evaluated by State-Trait Anxiety Inventory (STAI). Measures were taken two times: pretest and posttest. &lt;strong&gt;Results&lt;/strong&gt;: chemical analysis showed that carvone was the main component (64.5%) for Lippia alba essential oil and geranial (39.8%) for&lt;em&gt; Lippia citriodora&lt;/em&gt;. State and Trait anxiety scores showed a decrease in posttest study phase in comparison with pretest in all experimental groups (p&amp;lt;0.05). Cohen's D and Hedges’ G scores show a large size effect in state anxiety for experimental group treated with Lippia alba while moderate changes were found for the rest of variables in all experimental groups.&lt;strong&gt; Conclusion&lt;/strong&gt;: the essential oils extracted from &lt;em&gt;Lippia alba &lt;/em&gt;and&lt;em&gt; Lippia &lt;/em&gt;citriodora may be useful as a mean to counteract anxiety, specifically state anxiety showing short-terms benefits.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1377</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Paul Alan Arkin Alvarado- García&lt;sup&gt;1&lt;/sup&gt;,*, Marilú Roxana Soto-Vásquez&lt;sup&gt;2&lt;/sup&gt;, Luis Enrique Rosales-Cerquin&lt;sup&gt;1&lt;/sup&gt;, Bertha Mirella Alfaro-Ttito&lt;sup&gt;3&lt;/sup&gt;, Elda Maritza Rodrigo-Villanueva&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Escuela de Medicina. Universidad César Vallejo, Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Facultad de Farmacia y Bioquímica. Universidad Nacional de Trujillo, Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Escuela de Posgrado. Universidad Nacional de Trujillo, Trujillo, PERÚ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hamdoon Abdelhamid Mohammed</style></author><author><style face="normal" font="default" size="100%">Mohsen Saleh Al-Omer</style></author><author><style face="normal" font="default" size="100%">Adel Mohammed Ahmed</style></author><author><style face="normal" font="default" size="100%">Nadia Elbialy Hashish</style></author><author><style face="normal" font="default" size="100%">Hasan Meshal Alsaedi</style></author><author><style face="normal" font="default" size="100%">Suliman Abdulaziz Alghazy</style></author><author><style face="normal" font="default" size="100%">Ahmed Abdelfattah Hafez Abdellatif</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comparative Study for the Volatile Oil Constituents and Antimicrobial Activity of Rhanterium epapposum Oliv. Growing in Qassim, Saudi Arabia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Comparative study</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oils</style></keyword><keyword><style  face="normal" font="default" size="100%">Hot extraction. Cold extraction</style></keyword><keyword><style  face="normal" font="default" size="100%">Rhanterium epapposum</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">195-199</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt;&lt;em&gt; Rhanterium epapposum&lt;/em&gt; is an herbaceous plant widely distributed in the Gulf region and used by Bedouins as antiseptic for wounds, skin infections and in gastrointestinal disturbances. &lt;strong&gt;Aim:&lt;/strong&gt; The study aimed to compare the results obtained from volatile oil analysis of &lt;em&gt;R. epapposum &lt;/em&gt;growing in Buraydah, Qassim with reported data of the same plant growing in Riyadh “Al-Majmaah” and Northern border region of Saudi Arabia. Both cold and hot extracts of the &lt;em&gt;R. epapposum &lt;/em&gt;were used to find the best extraction method to be adopted as an antimicrobial agent. Methods: Volatile oils were distillated using Clevenger apparatus and analyzed by GC-MS. The plant powder was extracted by cold maceration and hot contentious extraction methods. Furthermore, antimicrobial activity was conducted using the agar diffusion method.&lt;strong&gt; Results:&lt;/strong&gt; The hydro-distillation of &lt;em&gt;R. epapposum&lt;/em&gt; growing in Qassim region yielded 0.5 % w/w of the total volatile oils. Moreover, forty-three compounds of 97.68% of the volatile oil components were identified while modephene, caryophyllene, linalyl acetate and epizonarene were the major components of volatile oils. Nevertheless, the volatile oils diversity and concentrations were found to be different in &lt;em&gt;R. epapposum &lt;/em&gt;growing in Buraydah, as compared with the plant growing in Riyadh and the northern border region of Saudi Arabia which almost due to the differences in the environmental condition. Among all extracts, ethyl acetate hot extract showed the best inhibition to bacterial strains while fugal strain &lt;em&gt;Candida albicans&lt;/em&gt; growth was better inhibited by hot &lt;em&gt;n&lt;/em&gt;-hexane extract. &lt;strong&gt;Conclusion:&lt;/strong&gt; Volatile oils were active against all microbial strains. Hot extracts were more active against bacterial strains while the opposite effects were found against &lt;em&gt;Candida albicans &lt;/em&gt;which was generally inhibited by the cold extracts.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">195</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Hamdoon Abdelhamid Mohammed&lt;sup&gt;1,2,*&lt;/sup&gt;, Mohsen Saleh Al-Omer&lt;sup&gt;1&lt;/sup&gt;, Adel Mohammed Ahmed&lt;sup&gt;1&lt;/sup&gt;, Nadia Elbialy Hashish&lt;sup&gt;1,6&lt;/sup&gt;, Hasan Meshal Alsaedi&lt;sup&gt;3&lt;/sup&gt;, Suliman Abdulaziz Alghazy&lt;sup&gt;3&lt;/sup&gt;, Ahmed Abdelfattah Hafez Abdellatif&lt;sup&gt;4,5&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Medicnal Chemistry and Pharmacognosy department, Faculty of Pharmacy, Qassim University, Buraydah, 51452, KINGDOM OF SAUDI ARABIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Pharmacognosy department, Faculty of Pharmacy, Al-Azhar University, Cairo, EGYPT.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Pharm. D. student, Faculty of Pharmacy, Qassim University, Buraydah, 51452, KINGDOM OF SAUDI ARABIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;4&lt;/sup&gt;Pharmaceutics and Industrial pharmacy department, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, EGYPT.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;5&lt;/sup&gt;Pharmaceutics department, Faculty of Pharmacy, Qassim University, Buraydah, 51452, KINGDOM OF SAUDI ARABIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Pharmacognosy , College of Pharmacy, Mansoura University, Egypt).&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Laura Aracely Contreras-Angulo</style></author><author><style face="normal" font="default" size="100%">Denisse Vega-Gaxiola</style></author><author><style face="normal" font="default" size="100%">Alexis Emus-Medina</style></author><author><style face="normal" font="default" size="100%">Jose Basilio Heredia</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pharmacognostic Study of Leaves of Hedeoma patens</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bioactives</style></keyword><keyword><style  face="normal" font="default" size="100%">Chemical/ Nutraceutical Industries</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oils</style></keyword><keyword><style  face="normal" font="default" size="100%">Hedeoma patens J</style></keyword><keyword><style  face="normal" font="default" size="100%">Oregano</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacognostic</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">921-924</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Oregano is a plant consumed as a spice and used to a lesser extent as a medicinal plant for the treatment of respiratory and stomach diseases, among others. Oregano is made up of a large number of species and is currently under study for its antimicrobial, antioxidant, anti-inflammatory and hypoglycemic properties. However, pharmacognostic studies of some wild species are lacking. &lt;strong&gt;Methods:&lt;/strong&gt; The present research aims to identify taxonomically and to evaluate the morphological characteristics of &lt;em&gt;Hedeoma patens&lt;/em&gt;, a plant used as oregano in Mexico. &lt;strong&gt;Results:&lt;/strong&gt; The specimens were identified as &lt;em&gt;Hedeoma patens&lt;/em&gt; J. and their main morphological features were trichome-pelted sites for synthesis of essential oils. &lt;strong&gt;Conclusion:&lt;/strong&gt; The plant used in Badiraguato, Sinaloa is &lt;em&gt;Hedeoma patens&lt;/em&gt; J. and the structures that synthesize phenolic compounds and essential oils could suggest a potential use of this plant and will form a basis for future research.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">921</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Laura Aracely Contreras-Angulo, Denisse Vega-Gaxiola, Alexis Emus-Medina, Jose Basilio Heredia* &lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Centro de Investigaci&amp;oacute;n en Alimentaci&amp;oacute;n y Desarrollo A.C., Carretera a Eldorado Km 5.5 Campo el Diez, Culiac&amp;aacute;n, Sinaloa, M&amp;Eacute;XICO. 80110.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Omar Mohamed Mohamed Sabry</style></author><author><style face="normal" font="default" size="100%">Abeer Mohamed El Sayed</style></author><author><style face="normal" font="default" size="100%">Salmin Khalid Alshalmani</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">GC/MS Analysis and Potential Cytotoxic Activity of Haplophyllum tuberculatum Essential Oils Against Lung and Liver Cancer Cells</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Cytotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oils</style></keyword><keyword><style  face="normal" font="default" size="100%">Haplophyllum tuberculatum</style></keyword><keyword><style  face="normal" font="default" size="100%">Liver cancer</style></keyword><keyword><style  face="normal" font="default" size="100%">Lung cancer.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">09/2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">66-69</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align:justify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; &lt;em&gt;Haplophyllum&lt;/em&gt;&lt;em&gt; tuberculatum&lt;/em&gt; is a plant belongs to family rutacee. It is rich in volatile oils, fixed oils, alkaloids, and furanocoumarins. It is well known for the huge number of folkloric uses in middle east. &amp;nbsp;&lt;strong&gt;Objective:&lt;/strong&gt; The aim of this study is to establish the chemical composition of the essential oils of Libyan &lt;em&gt;H. tuberculatum&lt;/em&gt; and to investigate their cytotoxic potentialities. &lt;strong&gt;Materials and Methods&lt;/strong&gt;&lt;strong&gt;:&lt;/strong&gt; The essential oils of the aerial parts and flowers of &lt;em&gt;H. tuberculatum&lt;/em&gt; growing in Libya were prepared by hydrodistillation. GC/MS analyses were performed on a Shimaduz capillary gas chromatograph (GC 17A ver.3) instrument directly coupled to mass spectrometer-MS QP5050A. Oil A and F of &lt;em&gt;H. tuberculatum&lt;/em&gt; at different concentrations (0-50 &amp;micro;g/ml) in DMSO were tested for cytotoxicity against human tumor cell lines. &lt;strong&gt;Results:&lt;/strong&gt; Oil yield was found 0.4 and 1.5 (v/w %) on dry weight basis respectively. GC/MS analysis resulted in identification of total 35 compounds. 15 compounds&amp;nbsp; were common to both oils. oil A of &lt;em&gt;H. tuberculatum &lt;/em&gt;exhibited antitumor activities against&lt;em&gt;.&lt;/em&gt; liver carcinoma cell line (HEPG2) and lung carcinoma cell line (H1299) 4.7 &amp;micro;g/ml and 4.1 &amp;micro;g/ml.&lt;strong&gt; Conclusion:&lt;/strong&gt; Essential oil of the aerial parts of &lt;em&gt;H. tuberculatum&lt;/em&gt; is potentially active against lung (H-1299), and liver (HEPG2) carcinoma cell lines. The observed cytotoxic, activities can be attributed to the dominance of &amp;alpha; and &amp;gamma;-terpinene in this oil.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">66</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Omar Mohamed Mohamed Sabry&lt;sup&gt;1,2*&lt;/sup&gt;, Abeer Mohamed El Sayed&lt;sup&gt;1&lt;/sup&gt;and Salmin Khalid Alshalmani&lt;sup&gt;2&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Kasr El-Einy Street, 11562, Cairo, Egypt.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy, Faculty of Pharmacy, Benghazi University, Benghazi, Libya.&lt;/p&gt;</style></auth-address></record></records></xml>