<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Lulu Adilla Latifah</style></author><author><style face="normal" font="default" size="100%">Nunuk Hariani Soekamto</style></author><author><style face="normal" font="default" size="100%">Akbar Tahir</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Green Algae Halimeda macroloba in Spermonde Archipelago: Phytochemical and in vitro Antibacterial Studies</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Halimeda macroloba</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical screening</style></keyword><keyword><style  face="normal" font="default" size="100%">Shrimp Pathogenic Bacteria</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1000-1004</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Green algae&lt;em&gt; Halimeda macroloba&lt;/em&gt; compounds active against human, fish, and shrimp pathogenic bacteria. It is one of the marine natural organisms (MNO) which is a diverse source of secondary metabolites. &lt;strong&gt;Objective:&lt;/strong&gt; We have set our goal towards determining the antimicrobial potential of crude extracts of green algae &lt;em&gt;H. macroloba&lt;/em&gt;. Materials and Methods: Three crude mixtures of Marine Natural Product (MNP) were obtained from macroalgae &lt;em&gt;Halimeda macroloba&lt;/em&gt; (Lae-Lae island, Spermonde Archipelago) by extraction (n-hexane, ethyl acetate, and methanol were used as solvents). &lt;strong&gt;Results:&lt;/strong&gt; Theses mixtures (phytochemical tests showed they contained steroids, terpenoids, and alkaloids) were screened for their activity against shrimp pathogenic bacteria (&lt;em&gt;Vibrio harveyi (&lt;/em&gt;M-120), &lt;em&gt;Aeromonas hydrophilla&lt;/em&gt;&amp;nbsp;and &lt;em&gt;Vibrio parahaemolyticus&lt;/em&gt; (T-170)). The obtained results confirmed weak antibacterial activity of studied extracts of&lt;em&gt; H. macroloba. &lt;/em&gt;The ethyl acetate extract was the most potent antimicrobial agent at a concentration of 4 μg/25 μl. The inhibition zones for the growth of A. hydrophilla (the most susceptible microorganism) and &lt;em&gt;V. harveyi &lt;/em&gt;were at 8.27 mm and 8.23 mm, respectively (inhibition zone was 15.2 mm for ciprofloxacin which was used as a positive control). &lt;strong&gt;Conclusion: &lt;/strong&gt;They might be even used in the future as alternatives to conventional drugs in aquaculture.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1000</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Lulu Adilla Latifah&lt;sup&gt;1&lt;/sup&gt;, Nunuk Hariani Soekamto&lt;sup&gt;2&lt;/sup&gt;, Akbar Tahir&lt;sup&gt;3,&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Fisheries Science Department, Faculty of Marine Science and Fisheries, Hasanuddin University, Makassar, 90245, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Chemistry, Mathematics and Natural Sciences Faculty, Hasanuddin University, Makassar, 90245, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Marine Science Department, Faculty of Marine Science and Fisheries, Hasanuddin University, Makassar, 90245, INDONESIA.&lt;/p&gt;
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