<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sakulrat Rattanakiat</style></author><author><style face="normal" font="default" size="100%">Pawitra Pulbutr</style></author><author><style face="normal" font="default" size="100%">Wanwisa Khunawattanakul</style></author><author><style face="normal" font="default" size="100%">Bunleu Sungthong</style></author><author><style face="normal" font="default" size="100%">Kritsanee Saramunee</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Prebiotic Activity of Polysaccharides Extracted from Jerusalem Artichoke Tuber and Development of Prebiotic Granules</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Granule</style></keyword><keyword><style  face="normal" font="default" size="100%">Helianthus tuberosus</style></keyword><keyword><style  face="normal" font="default" size="100%">Jerusalem artichoke</style></keyword><keyword><style  face="normal" font="default" size="100%">Prebiotic effect</style></keyword><keyword><style  face="normal" font="default" size="100%">Probiotics</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Research Article</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1402-1411</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Jerusalem artichoke tubers (JA) contain non-digestible carbohydrates, especially inulin-type fructans, which have been found to possess various benefits on human health, including the prebiotic effect. Although many studies established the prebiotic property of inulin or fructo-oligosaccharides, there are less information of the prebiotic potential of JA crude extract. This study aimed to investigate prebiotic effect of the JA extract and develop prebiotic granules from JA extract.&lt;strong&gt; Material and Methods: &lt;/strong&gt;Crude polysaccharide extract of JA was obtained using hot water and freeze-dried method. The selected probiotics, including&lt;em&gt; L. plantarum, L. acidophilus, B. longum&lt;/em&gt; and&lt;em&gt; B. breve &lt;/em&gt;were used in this study. The prebiotic effect of the JA extract was indicated by bacterial growth and acid production. Parallelly, JA extract granule formulation was developed to be a prebiotic food product. &lt;strong&gt;Results:&lt;/strong&gt; The JA extract at the highest concentration tested (2%) caused a significant increase in the growth and acid production of every probiotics tested, including&lt;em&gt; L. plantarum, L. acidophilus, B. longum &lt;/em&gt;and &lt;em&gt;B. breve.&lt;/em&gt; The growth promoting effects of the 2% JA extract were detected as early as 12 hour-incubation, and this action was maintained throughout the observed incubation period.&lt;strong&gt; Conclusions:&lt;/strong&gt; The developed JA extract granules possessed desirable properties with the moisture content of 4.00±0.20%. The formulated granule was soluble in water and produced a brown and clear solution with slightly sweet taste. Nonetheless,&lt;em&gt; in vivo&lt;/em&gt; experiments on the prebiotic effect of the developed preparation should be performed further.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1402</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sakulrat Rattanakiat&lt;sup&gt;1,&lt;/sup&gt;*, Pawitra Pulbutr&lt;sup&gt;1&lt;/sup&gt;, Wanwisa Khunawattanakul&lt;sup&gt;1&lt;/sup&gt;, Bunleu Sungthong&lt;sup&gt;1&lt;/sup&gt;, Kritsanee Saramunee&lt;sup&gt;1 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, Mahasarakham University, Maha Sarakham, 44150, THAILAND.&lt;/p&gt;
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