<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Siti Thomas Zulaikhah</style></author><author><style face="normal" font="default" size="100%">Helmia Fitri Nurul Aini</style></author><author><style face="normal" font="default" size="100%">Anisa Setyo Rini</style></author><author><style face="normal" font="default" size="100%">Bagus Hidayaturrahman Abiyyu</style></author><author><style face="normal" font="default" size="100%">Elvita Apriska Tiara Dewi</style></author><author><style face="normal" font="default" size="100%">Arrizki Azka Pratama</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Tender Coconut Water (Cocos nucifera L.) Can Increase Antioxidant Enzymes and Decrease MDA Levels: Experimental Study on Cigarette Smoke-Exposed Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Catalase</style></keyword><keyword><style  face="normal" font="default" size="100%">Cigarette smoke</style></keyword><keyword><style  face="normal" font="default" size="100%">Malondyaldehyde</style></keyword><keyword><style  face="normal" font="default" size="100%">Superoxide dismutase</style></keyword><keyword><style  face="normal" font="default" size="100%">Tender coconut water</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">469-476</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Cigarette smoke exposure increase free radicals in the body in the form of Reactive Oxygen Species (ROS). Excessive levels of ROS can cause an imbalance between the amount of oxidants and antioxidants that trigger oxidative stress. The state of oxidative stress can be seen from the decrease in antioxidant enzymes, such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and increased levels of malondialdehyde (MDA). Tender coconut water contains a variety of substances that are beneficial to the body, including L-arginine and Vitamin C which can increase antioxidant enzymes and reduce oxidative stress. &lt;strong&gt;Aim and Objectives&lt;/strong&gt;: This study aims to determine the effect of giving tender coconut water on increasing antioxidant enzymes such as SOD and CAT and decreasing MDA in rats exposed to cigarette smoke. &lt;strong&gt;Material and Methods: &lt;/strong&gt;Experimental research by Post-Test Only Control Group Design study used 24 rats divided into 4 groups, K1 was the control, K2 was the negative control exposed to cigarette smoke, K3 the positive control was given vitamin E and K4 the treatment group. Furthermore, sampling was continued by examining the levels of SOD and CAT using ELISA (Enzyme- Linked Immunosorbent Assay), while MDA using spectrophotometry. The SOD, CAT, and MDA data were processed using SPSS with the One Way Anova. &lt;strong&gt;Results: &lt;/strong&gt;The administration of tender coconut water at a dose of 8mL/200grBW/day and vitamin E at a dose of 1.8 mg/200gBW/day for 14 days increasing SOD levels, CAT levels and reduce MDA levels.&lt;strong&gt; Conclusion:&lt;/strong&gt; It can be concluded that tender coconut water can increase antioxidant enzymes and reduce MDA in rats exposed to cigarette smoke.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">469</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Siti Thomas Zulaikhah&lt;sup&gt;1,*&lt;/sup&gt;, Helmia Fitri Nurul Aini&lt;sup&gt;2&lt;/sup&gt;, Anisa Setyo Rini&lt;sup&gt;3&lt;/sup&gt;, Bagus Hidayaturrahman Abiyyu&lt;sup&gt;3&lt;/sup&gt;, Elvita Apriska Tiara Dewi&lt;sup&gt;3&lt;/sup&gt;, Arrizki Azka Pratama&lt;sup&gt;4&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Public Health Departement of Medical Faculty, Universitas Islam Sultan Agung, Semarang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;General Practitioner, Semarang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Medical Student of Medical Faculty, Universitas Islam Sultan Agung, Semarang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Student Program Master of Biomedical Science, Faculty of Medicine, Universitas Islam Sultan Agung, Semarang, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">G. Narayanan</style></author><author><style face="normal" font="default" size="100%">K Prabhu</style></author><author><style face="normal" font="default" size="100%">Anath Bandhu Chaudhury</style></author><author><style face="normal" font="default" size="100%">Mudiganti Ram Krishna Rao</style></author><author><style face="normal" font="default" size="100%">V S Kalai Selvi</style></author><author><style face="normal" font="default" size="100%">N S Muthiah</style></author><author><style face="normal" font="default" size="100%">Sruthi Dinakar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Cardioprotective Role of Partharishtam on Isopreterenol Induced Myocardial Infarction in Animal Model</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Catalase</style></keyword><keyword><style  face="normal" font="default" size="100%">Creatine phosphokinase</style></keyword><keyword><style  face="normal" font="default" size="100%">GSH</style></keyword><keyword><style  face="normal" font="default" size="100%">Isoproterenol</style></keyword><keyword><style  face="normal" font="default" size="100%">Myocardial Infarction</style></keyword><keyword><style  face="normal" font="default" size="100%">Partharishtam</style></keyword><keyword><style  face="normal" font="default" size="100%">Polyherbal</style></keyword><keyword><style  face="normal" font="default" size="100%">Propranolol</style></keyword><keyword><style  face="normal" font="default" size="100%">SOD</style></keyword><keyword><style  face="normal" font="default" size="100%">Troponin I</style></keyword><keyword><style  face="normal" font="default" size="100%">Troponin T</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">591-595</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Myocardial infarction (MI) is one of the key causes of high death rate globally. We report the cardio protective effect of an Ayurvedic polyherbal formulation Partharishtam on isoproterenol induced myocardial infarction on albino rats. Administration of Isoproterenol to normal albino rat triggers MI evident from the significant changes in key biomolecules tested in blood serum and cardiac tissues. The cardio protective role of Partharishtam was compared with a standard medicine, Propranolol on some of the known identifying markers of MI such as, Troponin I and T, creatine phosphokinase serum (CPK-S), creatine phosphokinase myoglobulin isozyme fraction (CPK-MB) and oxidative enzymes like super oxide dismutase (SOD), reduced glutathione (GSH) and catalase. There was an appreciable decrease in the levels of Troponin 1 and T, CPK-S and CPK-MB after the treatment of Partharishtam on Isoproterenol induced MI rats. In vivo anti-oxidative enzyme studies also revealed the increase in the levels of SOD, GSH and catalase to near normalcy after the treatment of Partharishtam in MI rats, which is very much comparable to the commonly used drug Propranolol to treat MI patients. Histopathological analysis confirmed the cardio protective properties of Partharistham in rat model. We did not find any side effects or toxicity of Partharishtam when tested on the normal rats. Thus, polyherbal formulation Partharishtam could be considered as safe medicine for MI.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">591</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;G. Narayanan&lt;sup&gt;1&lt;/sup&gt;, K Prabhu&lt;sup&gt;2&lt;/sup&gt;, Anath Bandhu Chaudhury&lt;sup&gt;3&lt;/sup&gt;, Mudiganti Ram Krishna Rao&lt;sup&gt;4,&lt;/sup&gt;*, V S Kalai Selvi&lt;sup&gt;5&lt;/sup&gt;, N S Muthiah&lt;sup&gt;6&lt;/sup&gt;, Sruthi Dinakar&lt;sup&gt;7&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Research Scholar, Dept. of Anatomy, Sree Balaji Medical College and Hospital, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Associate Professor, Dept of Anatomy, Sree Balaji Medical College and Hospital, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Assistant Professor of Biology, Chair Department of Natural Sciences, Stillman College, P. O. Box. 1430, Tuscaloosa, Alabama, USA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Professor, Dept of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Professor, Dept of Biochemistry, Sree Balaji Medical College and Hospital, Chennai, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Pharmacology, Sree Balaji Medical College and Hospital, Chennai, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Ayurvedic Physician, Kottakkal Arya Vaidhya Sala, Chennai, INDIA.&lt;/p&gt;
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