<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Akanksha Mittal</style></author><author><style face="normal" font="default" size="100%">Sunil Tejaswi</style></author><author><style face="normal" font="default" size="100%">Mruthunjaya K</style></author><author><style face="normal" font="default" size="100%">Suneeth Shetty</style></author><author><style face="normal" font="default" size="100%">Ambikathanaya UK</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comparison of Antibacterial Activity of Calcium Hydroxide, Azadirachta Indica (Neem), Ocimum Tenuiflorum (Tulsi) and Punica Granatum (Pomegranate) Gels as Intracanal Medicaments Against Enterococcus Faecalis: An in-vitro Study</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Calcium hydroxide</style></keyword><keyword><style  face="normal" font="default" size="100%">Enterococcus faecalis</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal</style></keyword><keyword><style  face="normal" font="default" size="100%">Intracanal medicaments</style></keyword><keyword><style  face="normal" font="default" size="100%">Microbial sensitivity tests</style></keyword><keyword><style  face="normal" font="default" size="100%">Root canal therapy</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2017</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">988-994</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Aim: &lt;/strong&gt;This study aimed to evaluate the antibacterial activity of Calcium hydroxide, Azadirachta indica (Neem), Ocimum tenuiflorum (Tulsi) and Punica granatum (Pomegranate) gels as intracanal medicaments against &lt;em&gt;Enterococcus faecalis&lt;/em&gt;. &lt;strong&gt;Methodology:&lt;/strong&gt; Crude extracts of Pomegranate peel, Neem leaves and Tulsi leaves were used to determine MIC following which gels of 5% neem, 10% tulsi and 10% pomegranate were prepared. Forty-eight single rooted human premolars were procured and inoculated with E.faecalis for 7 days. Specimens were then randomly distributed into 4 groups.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Group I- Calcium hydroxide&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Group II- 5% A. indica (Neem) gel&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Group III- 10% O. tenuiflorum (Tulsi) gel&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Group IV-10%&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;P. granatum (Pomegranate) gel The experimental gels were then introduced into the samples and were sealed at both ends. The antimicrobial activity of medicaments was assessed by measuring CFU/ml at the end of 1, 3 and 5 days. &lt;strong&gt;Results:&lt;/strong&gt; Calcium hydroxide showed the maximum antibacterial activity (5.3X10&lt;sup&gt;4 &lt;/sup&gt;CFU/ml) followed by Pomegranate gel (5.4 X10&lt;sup&gt;4&lt;/sup&gt; CFU/ml) with no statistically significant difference between them. Similarly, no statistically significant difference was observed between the mean CFU/ml values of the neem (10.2 X10&lt;sup&gt;4 &lt;/sup&gt;CFU/ml) and tulsi gel (10.2 X10&lt;sup&gt;4&lt;/sup&gt; CFU/ml). However, pomegranate gel showed statistically significant antibacterial activity when compared to Neem and Tulsi. (Table 1, Table 2, Table 3, table 4) (Figure 1). &lt;strong&gt;Conclusion:&lt;/strong&gt; Calcium hydroxide showed the best antibacterial activity against E.faecalis. Among herbal gels, pomegranate showed the maximum antibacterial activity, however, further &lt;em&gt;in-vivo&lt;/em&gt; research is required for it to be used as a sole intracanal medicament clinically.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">988</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Akanksha Mittal, Sunil Tejaswi*, Mruthunjaya K, Suneeth Shetty, Ambikathanaya UK&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;JSS Dental College and Hospital, Mysuru, INDIA.&lt;/p&gt;
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