<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Candra Irawan</style></author><author><style face="normal" font="default" size="100%">Maman Sukiman</style></author><author><style face="normal" font="default" size="100%">Ismail</style></author><author><style face="normal" font="default" size="100%">Imalia Dwi Putri</style></author><author><style face="normal" font="default" size="100%">Andita Utami</style></author><author><style face="normal" font="default" size="100%">Avisani Dewanta</style></author><author><style face="normal" font="default" size="100%">Aulia Noviyanti</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Optimization of the Ultrasound Assisted Extraction of Phaleria macrocarpa (Scheff.) Boerl. Fruit Peel and its Antioxidant and Anti-Gout Potential</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-gout</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Phaleria macrocarpa (Scheff.) Boerl.</style></keyword><keyword><style  face="normal" font="default" size="100%">Ultrasound-assisted extraction</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">397-405</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Aims:&lt;/strong&gt; This study aimed to obtain the skin extract of &lt;em&gt;Phaleria macrocarpa&lt;/em&gt; (Scheff.) Boerl. through the application of ultrasound-assisted extraction (UAE) with variations in time and amplitude to produce optimal extraction conditions. The extract's potential as an antioxidant with 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical inhibition parameters, and its potential as an anti-gout.&lt;strong&gt; Results:&lt;/strong&gt; The yield of crude ethanol extract of&lt;em&gt; Phaleria macrocarpa &lt;/em&gt;(Scheff.) Boerl rind obtained from the UAE process ranged from 18 to 21%. The phytochemical test results of &lt;em&gt;Phaleria macrocarpa&lt;/em&gt; fruit peel extract contain phenolic compounds, tannins, saponins, and alkaloids. Extract B was treated for 35 minutes and had an amplitude of 65% with an antioxidant activity IC&lt;sub&gt;50 &lt;/sub&gt;of 52.01 ± 0.06 mg/L and a reduction of uric acid level of 90.49 ± 0.08. &lt;strong&gt;Conclusion&lt;/strong&gt;: The ethanol extract of the fruit peel of &lt;em&gt;Phaleria macrocarpa&lt;/em&gt; from the UAE has the potential as a source of antioxidants and anti-gout.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><section><style face="normal" font="default" size="100%">397</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Candra Irawan&lt;sup&gt;1&lt;/sup&gt;, Maman Sukiman&lt;sup&gt;2&lt;/sup&gt;, Ismail&lt;sup&gt;3&lt;/sup&gt;, Imalia Dwi Putri&lt;sup&gt;1&lt;/sup&gt;, Andita Utami&lt;sup&gt;3&lt;/sup&gt;,*, Avisani Dewanta&lt;sup&gt;3&lt;/sup&gt;, Aulia Noviyanti&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Food Nanotechnology, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Industrial Waste Treatment, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Chemical Analysis, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ismail</style></author><author><style face="normal" font="default" size="100%">Candra Irawan</style></author><author><style face="normal" font="default" size="100%">Maman Sukiman</style></author><author><style face="normal" font="default" size="100%">Imalia Dwi Putri</style></author><author><style face="normal" font="default" size="100%">Andita Utami</style></author><author><style face="normal" font="default" size="100%">M. Ilham Kumala Zalni</style></author><author><style face="normal" font="default" size="100%">Ratna Komala Putri</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Optimization of Ultrasound-Assisted Extraction of Andrographis paniculata Nees Leaves, Phytochemical Screening, Total Phenolic Content and Anti-Gout Potential Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Andrographis paniculata Nees</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-gout</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical screening</style></keyword><keyword><style  face="normal" font="default" size="100%">total phenolic content</style></keyword><keyword><style  face="normal" font="default" size="100%">Ultrasound-assisted extraction</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">432-438</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Gout is a type of arthritis that causes painful inflammation in one or more joints. In gout, an increase in uric acid in the blood triggers the formation of crystals, causing joint pain. Indonesia is a country rich in the biodiversity of medicinal plant species. Therefore, its flora offers promising therapy for gout, one of which is&lt;em&gt; Andrographis paniculata &lt;/em&gt;Nees. This study aims to obtain the leaf extract of &lt;em&gt;A. paniculata &lt;/em&gt;through the application of ultrasound-assisted extraction (UAE) with variations in time and amplitude to produce optimal extraction conditions. Then the extract obtained was subjected to phytochemical screening, a total phenolic content test and uric acid test. The results of phytochemical screening of &lt;em&gt;A. paniculata&lt;/em&gt; leaf extract using UAE contained saponins, phenols, tannins and alkaloids. The high total phenolic content has an effect on the high potential for reducing uric acid levels. Sample B with a time variation of 35 minutes and an amplitude of 65% showed the highest total phenolic content and potential for reducing uric acid levels compared to the other samples, which were 1104.53 ± 0.5 mg GAE/g extract and 72.81±0.2 %, respectively. From the results of the study, it can be concluded that the UAE extract from the leaves of &lt;em&gt;A. paniculata&lt;/em&gt; has good potential as an anti-gout agent.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">432</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ismail&lt;sup&gt;1&lt;/sup&gt;, Candra Irawan&lt;sup&gt;2&lt;/sup&gt;, Maman Sukiman&lt;sup&gt;3,*&lt;/sup&gt;, Imalia Dwi Putri&lt;sup&gt;2&lt;/sup&gt;, Andita Utami&lt;sup&gt;1&lt;/sup&gt;, M. Ilham Kumala Zalni&lt;sup&gt;3&lt;/sup&gt;, Ratna Komala Putri&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Chemical Analysis, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Food Nanotechnology, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Industrial Waste Treatment, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Maman Sukiman</style></author><author><style face="normal" font="default" size="100%">Candra Irawan</style></author><author><style face="normal" font="default" size="100%">Ismail</style></author><author><style face="normal" font="default" size="100%">Imalia Dwi Putri</style></author><author><style face="normal" font="default" size="100%">Andita Utami</style></author><author><style face="normal" font="default" size="100%">Avisani Dewanta</style></author><author><style face="normal" font="default" size="100%">Wira Aditia Septian</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Optimization of Ultrasound-Assisted Extraction of Tinospora crispa Stem, Phytochemical Screening, Total Phenolic Content and Anti Gout Potential Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-gout potential activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Tinospora crispa (L.) Hook. f &amp; Thomson Stem</style></keyword><keyword><style  face="normal" font="default" size="100%">total phenolic content</style></keyword><keyword><style  face="normal" font="default" size="100%">Ultrasound-assisted extraction</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">308-314</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Aims: &lt;/strong&gt;This study aimed to obtain the stem extract of&lt;em&gt; Tinospora crispa&lt;/em&gt; (L.) Hook. f &amp;amp; Thomson through the application of ultrasound-assisted extraction (UAE) with variations in time and amplitude to produce optimal extraction conditions. The extract's potential as an anti-gout. &lt;strong&gt;Results: &lt;/strong&gt;The yield of crude ethanol extract of &lt;em&gt;Tinospora crispa &lt;/em&gt;(L.) Hook. f &amp;amp; Thomson obtained from the UAE process ranged from 4.49% to 10.60%. The phytochemical test results of&lt;em&gt; Tinospora crispa &lt;/em&gt;stem extract contain saponins, tannins and alkaloids. Extract C was treated for 45 minutes and had an amplitude of 60% with a total phenolic content of 981.37 ± 0.7 mg/L and a reduction of uric acid level of 53.22 ± 0.1%.&lt;strong&gt; Conclusion&lt;/strong&gt;: The ethanol extract of the &lt;em&gt;Tinospora crispa&lt;/em&gt; stem from the UAE has the potential as a source of anti-gout.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">308</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Maman Sukiman&lt;sup&gt;1&lt;/sup&gt;, Candra Irawan&lt;sup&gt;2&lt;/sup&gt;, Ismail&lt;sup&gt;3,*&lt;/sup&gt;, Imalia Dwi Putri&lt;sup&gt;2&lt;/sup&gt;, Andita Utami&lt;sup&gt;3&lt;/sup&gt;, Avisani Dewanta&lt;sup&gt;3&lt;/sup&gt;, Wira Aditia Septian&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Industrial Waste Treatment, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Food Nanotechnology, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Chemical Analysis, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Candra Irawan</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Muhammad Hanafi</style></author><author><style face="normal" font="default" size="100%">Fadlina Chany Saputri</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Application of Ultrasound-Assisted Extraction on the Stem Bark of Rhinachantus Nasutus (L.) Kurz, Total Phenolic, and Its Potential as Antioxidant and Inhibitor of Alpha-Glucosidase Enzyme Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alpha-glucosidase enzyme</style></keyword><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Rhinachantus nasutus (L.) Kurz</style></keyword><keyword><style  face="normal" font="default" size="100%">Total phenolics content</style></keyword><keyword><style  face="normal" font="default" size="100%">Ultrasound-assisted extraction</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1297-1303</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Aims: &lt;/strong&gt;This study aims to obtain a stem bark extract of &lt;em&gt;Rhinachantus nasutus&lt;/em&gt; (L.) Kurz through the application of ultrasound-assisted extraction (UAE) and reveal: the total phenolic content in the extract; The extract's potential as an antioxidant with copper-reducing strength parameters, and its potential as an antidiabetic by inhibiting alpha-glucosidase activity. &lt;strong&gt;Results:&lt;/strong&gt; The crude ethanol extract of R. nasutus stem bark obtained from the UAE process was 7.4896 g with a yield of 4.99%. The high total phenolic content, namely 677.3343±0.0007 mg GAE / g sample, the antioxidant activity test using the CUPRAC method gave an IC&lt;sub&gt;50 &lt;/sub&gt;value of 18.43±0.20 mg / L. In addition, the ethanol extract of stem bark has a high ability to inhibit the activity of the alpha-glucosidase enzyme with an IC&lt;sub&gt;50&lt;/sub&gt; value of 10.95±0.28 mg / L. &lt;strong&gt;Conclusion:&lt;/strong&gt; The ethanol extract of the stem bark of R. nasutus from UAE has the potential as a source of antioxidants and antidiabetic.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1297</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Candra Irawan&lt;sup&gt;1,2&lt;/sup&gt;, Berna Elya&lt;sup&gt;1,&lt;/sup&gt;*, Muhammad Hanafi&lt;sup&gt;3&lt;/sup&gt;, Fadlina Chany Saputri&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy Universitas Indonesia, Depok 16424, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Analytical Chemistry; Politeknik AKA Bogor; Bogor 16154; INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Research Center for Chemistry, Indonesian Institute of Science, Serpong (LIPI Indonesia), INDONESIA.&lt;/p&gt;
</style></auth-address></record></records></xml>