<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Elidahanum Husni</style></author><author><style face="normal" font="default" size="100%">Friardi Ismed</style></author><author><style face="normal" font="default" size="100%">Awaliana</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Standardization Extracts and Simplicia of Limau Sundai Peel (Citrus x aurantiifolia 'sundai'), Determine Content of Nobiletin and Antibacterial Activity Test</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Citrus x aurantiifolia('sundai')</style></keyword><keyword><style  face="normal" font="default" size="100%">Nobiletin</style></keyword><keyword><style  face="normal" font="default" size="100%">standardization</style></keyword><keyword><style  face="normal" font="default" size="100%">Sundai lime peel fruit</style></keyword><keyword><style  face="normal" font="default" size="100%">TLC Densitometry</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1323-1331</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction&lt;/strong&gt;: One type of oranges typical of West Sumatra, which is widely used as traditional medicine is sundai lime (&lt;em&gt;Citrus &lt;/em&gt;x &lt;em&gt;aurantiifolia&lt;/em&gt; 'sundai'); &lt;strong&gt;Aims:&lt;/strong&gt; therefore, it is necessary to standardize extracts and Simplicia, determine the content of nobiletin, and antibacterial activity test. &lt;strong&gt;Methods&lt;/strong&gt;: The standardization method was used refer to Farmakope Herbal Indonesia. TLC Densitometry was used to determine the content of the nobiletin, and the diffusion method to antibacterial activity test. To get a good standardization, the sundai lime was taken from three regions: Bukittinggi, Pariaman, and Solok. &lt;strong&gt;Results: &lt;/strong&gt;From these three regions, conclusions drawn from the macroscopic fruit peel slices were uneven and had distinctive odors. The outer surface is brown, and the inner surface is yellowish-white. From the microscopic was identified fragments in sundai lime peels consisting of hair covering, ladder-shaped transport, parenchyma with secretion cells, oxalate crystals, and parenchyma tissue and stomata. Water-soluble extract content of Simplicia ≤ 24.90 %, and ethanol-soluble extract content ≤ 17.66 %. Non-specific parameters are loss on drying ≤ 5.65 %, total ash content ≤ 5.14 %, and acid insoluble ash content ≤ 0.80 %. The specific parameters were crude extract, black, characteristic odor, Rf of nobiletin was 0.75. Rendement extract ≥ 18.80 %. Non-specific parameters of extract were water content ≤ 18.37 %, total ash content ≤ 3.93 %, and non-acidic ash content ≤ 0.27 %. The nobiletin content in the sundai lime extract Pariaman was 0.33 %, Solok 0.59 %, and Bukittinggi 0.47 %. The antibacterial test with diffusion method in three regions has moderate activities as concentrations of 20% and 15%. &lt;strong&gt;Conclusion:&lt;/strong&gt; Sundai lime had Antibacterial activity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1323</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Elidahanum Husni*, Friardi Ismed, Awaliana&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Pharmacy, Andalas University, INDONESIA.&lt;/p&gt;
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