<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Himyatul Hidayah</style></author><author><style face="normal" font="default" size="100%">Surya Amal</style></author><author><style face="normal" font="default" size="100%">Nia Yuniarsih</style></author><author><style face="normal" font="default" size="100%">Farhamzah</style></author><author><style face="normal" font="default" size="100%">Anggun Hari Kusumawati</style></author><author><style face="normal" font="default" size="100%">Neni Sri Gunarti</style></author><author><style face="normal" font="default" size="100%">Ermi Abriyani</style></author><author><style face="normal" font="default" size="100%">Iin Lidia Putama Mursal</style></author><author><style face="normal" font="default" size="100%">Adinda Khansa Sundara</style></author><author><style face="normal" font="default" size="100%">Maulana Yusuf Alkandahri</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Sun Protection Factor Activity of Jamblang Leaves Serum Extract (Syzygium cumini)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Serum</style></keyword><keyword><style  face="normal" font="default" size="100%">Sun protection factor</style></keyword><keyword><style  face="normal" font="default" size="100%">Syzygium cumini</style></keyword><keyword><style  face="normal" font="default" size="100%">Ultraviolet.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">134-140</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;The development of serum preparations containing natural ingredients for sun protection is growing rapidly. Jamblang (&lt;em&gt;Syzygium cumini&lt;/em&gt;) leaves are rich in phenolic compounds that can inhibit free radicals causing premature aging. Therefore, this study aims to determine the potential of &lt;em&gt;S. cumin&lt;/em&gt;i serum extract as sun protection. &lt;strong&gt;Methods:&lt;/strong&gt; The extract was prepared and included in the serum base. The formulations were evaluated for rheological, pH, dispersion coefficient, and stability examinations. Furthermore, Sun Protection Factor was tested using a UV-Vis spectrophotometer. &lt;strong&gt;Results: &lt;/strong&gt;The test of phytochemical compounds showed the presence of alkaloids, flavonoids, polyphenols, tannins, saponins, quinones, monoterpenoids, sesquiterpenoids, triterpenoids, and steroids. The result also showed that all serum formulations met the predetermined requirements. Furthermore, the extract has protective activity against ultraviolet rays, which was indicated by the SPF value. The higher the dose of &lt;em&gt;S. cumini&lt;/em&gt; extracts in the serum formulation, the higher the value obtained. Formulations 1, 2, and 3 have SPF of 9.35±0.11, 13.26±0.16, and 26.05±0.31, respectively. This indicates that they all met the Indonesian National Standard, that a sun protection preparation must have a minimum protection factor of 4. &lt;strong&gt;Conclusion: &lt;/strong&gt;&lt;em&gt;S. cumini&lt;/em&gt; extract serum has the potential to be developed as a new sun protection agent against ultraviolet radiation. However, further studies are still needed to determine the mechanism of its constituent active compounds.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">134</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Himyatul Hidayah&lt;sup&gt;1&lt;/sup&gt;, Surya Amal&lt;sup&gt;1&lt;/sup&gt;, Nia Yuniarsih&lt;sup&gt;1&lt;/sup&gt;, Farhamzah&lt;sup&gt;1&lt;/sup&gt;, Anggun Hari Kusumawati&lt;sup&gt;1&lt;/sup&gt;, Neni Sri Gunarti&lt;sup&gt;1&lt;/sup&gt;, Ermi Abriyani&lt;sup&gt;1&lt;/sup&gt;, Iin Lidia Putama Mursal&lt;sup&gt;1&lt;/sup&gt;, Adinda Khansa Sundara&lt;sup&gt;2&lt;/sup&gt;, Maulana Yusuf Alkandahri&lt;sup&gt;1,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, Universitas Buana Perjuangan Karawang, Karawang, West Java, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Student of Pharmacy, Faculty of Pharmacy, Universitas Buana Perjuangan Karawang, Karawang, West Java, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gumilar Adhi Nugroho</style></author><author><style face="normal" font="default" size="100%">Febrika Wediasari</style></author><author><style face="normal" font="default" size="100%">Zahra Fadhilah</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Heri Setiawan</style></author><author><style face="normal" font="default" size="100%">ELFAHMI</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Potency of Antidiabetic Effects of the Combination of Syzygium cumini and Andrographis paniculata in Rats with High-Fat Dietand Streptozotocin-Induced Diabetes</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Andrographis paniculata</style></keyword><keyword><style  face="normal" font="default" size="100%">Combination</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetes</style></keyword><keyword><style  face="normal" font="default" size="100%">Syzygium cumini</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">406-412</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;em&gt;Andrographis paniculata&lt;/em&gt; (AP) and &lt;em&gt;Syzygium cumini &lt;/em&gt;(SC) are known for their antihyperglycemic effects. However, the combined effects of these plants have not yet been assessed. This study evaluated the oral acute toxicity and&lt;em&gt; in vivo &lt;/em&gt;antihyperglycemic effects of the extract combining AP and SC (SCAP) in rats with high-fat diet- and streptozotocin (STZ)-induced diabetes. Thirteen female DDY mice for toxicity test were divided into three groups and orally administered one dose SCAP (0, 300, or 2000 mg/kg). On day 15, animals were euthanized, their internal organs were observed, and blood samples were collected for clinical biochemistry analyses.&lt;em&gt; In vivo&lt;/em&gt; antihyperglycemic activity was examined in male Sprague- Dawley rats-induced diabetes. Diabetic rats were assigned to once-daily oral treatment with metformin, AP, SC or SCAP for 1 week. Concerning toxicity, SCAP had no effects on liver and kidney and histology of these organs displayed no abnormalities. Blood glucose levels had a tendency to reduce in treatment groups compared with the findings in the diabetic control group. SCAP treatment protected rats against pancreatic damage. These results illustrated that the combined SCAP treatment had beneficial effects on blood glucose levels and pancreatic β-cell function, in rats-induced diabetes.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><section><style face="normal" font="default" size="100%">406</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Gumilar Adhi Nugroho&lt;sup&gt;1&lt;/sup&gt;, Febrika Wediasari&lt;sup&gt;1&lt;/sup&gt;, Zahra Fadhilah&lt;sup&gt;1&lt;/sup&gt;, Berna Elya&lt;sup&gt;1,*&lt;/sup&gt;, Heri Setiawan&lt;sup&gt;2&lt;/sup&gt;, Elfahmi&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Laboratorium of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, University of Indonesia, Depok, Jawa Barat, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratorium of Pharmacology, Faculty of Pharmacy, University of Indonesia, Depok, Jawa Barat, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;School of Pharmacy, Institut Teknologi Bandung, Bandung, Jawa Barat, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Atini Solawati</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Heri Setiawan</style></author><author><style face="normal" font="default" size="100%">Raysa Yunda Pratiwi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Subchronic Toxicity Studies of a Combined Andrographis paniculata (Burm.f.) Nees, Syzygium cumini (L) Skeels, and Caesalpinia sappan L Extract in Sprague-Dawley Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Andrographis paniculata</style></keyword><keyword><style  face="normal" font="default" size="100%">Caesalpinia sappan</style></keyword><keyword><style  face="normal" font="default" size="100%">Rats.</style></keyword><keyword><style  face="normal" font="default" size="100%">Subchronic yoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Syzygium cumini</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">531-535</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt;&lt;em&gt; Andrographis paniculata, Syzygium cumini and Caesalpinia sappan&lt;/em&gt; (ASC) are plants that are widely used as traditional medicines in treating diabetes. The acute toxicity test results of the combination of these three plants were safe up to 5000 mg/Kg BB. &lt;strong&gt;Objectives: &lt;/strong&gt;To evaluate subchronic toxicity of a combined ASC extract. &lt;strong&gt;Methods: &lt;/strong&gt;Male and female &lt;em&gt;Sprague Dawley &lt;/em&gt;rats were acclimatized for 14 days and then fed a normal diet with ASC extract at doses of 150, 575 and 1000 mg/kg BW daily for 135 days. At the end of the study, the rats were sacrificed and then blood, heart, pulmonary, liver, kidneys, spleen and pancreas were collected. Result: The results showed no abnormality in the experimental group compared with the control group. All values of other parameters assessed remained within the normal range.&lt;strong&gt; Conclusions:&lt;/strong&gt; The combination of ASC extract given orally for 135 days to male and female rats did not show any subchronic toxicity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><accession-num><style face="normal" font="default" size="100%">07</style></accession-num><section><style face="normal" font="default" size="100%">531</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Atini Solawati, Berna Elya*, Heri Setiawan, Raysa Yunda Pratiwi&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Pharmacy, Universitas Indonesia, Depok 16424, West Java, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Eem Masaenah</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Heri Setiawan</style></author><author><style face="normal" font="default" size="100%">Zahra Fadhilah</style></author><author><style face="normal" font="default" size="100%">Varda Arianti</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Quantification of Andrographolide in Andrographis paniculata (Burm.f.) Nees, Myricetin in Syzygium cumini (L.) Skeels, and Brazilin in Caesalpinia sappan L. by HPLC Method</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Andrographis paniculata</style></keyword><keyword><style  face="normal" font="default" size="100%">Caesalpinia sappan</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Marker compounds</style></keyword><keyword><style  face="normal" font="default" size="100%">Quality control</style></keyword><keyword><style  face="normal" font="default" size="100%">Syzygium cumini</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1437-1444</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction&lt;/strong&gt;: Andrographolide, myricetin, and brazilin are bioactive compounds from &lt;em&gt;Andrographis paniculata&lt;/em&gt;, &lt;em&gt;Syzygium cumini,&lt;/em&gt; and Caesalpinia &lt;em&gt;sappan &lt;/em&gt;plants that have potential as medicinal ingredients. Objectives: To determine the levels of andrographolide in A. paniculata herb extract (APE), myricetin in S. cumini leaf extract (SCE), and brazilin in &lt;em&gt;C. sappan&lt;/em&gt; wood extract (CSE) as marker compounds for extract quality control using the HPLC method. Methods: The separation was carried out on a reverse-phase C18 column (150 x 4.6 mm; 5 μm). The isocratic was prepared from methanol - water (50:50 v/v); 0.1% orthophosphoric acid - methanol (60:40 v/v); and 0,3% acetic acid - acetonitrile (85.5: 14.5 v/v) as mobile phase with flow rate 1 mL/min for andrographolide, myricetin, and brazilin determination, respectively and detection using UV detector at a wavelength of 254 nm, 369 nm, and 280 nm, respectively. Results: The linear regression for andrographolide was y = 14113x + 5948.8 (r2= 0.9994); myricetin was y = 87766x – 138895 (r2=0.9996); and brazilin was y = 18520x – 42668 (r2=0.9992). The andrographolide content in APE was found to be 14.4686 %. The myricetin content in SCE was found to be 0.3190 %. The brazilin content in CSE was found to be 2.1280 %. Conclusion: The described HPLC method was successfully used for the analysis of the APE, SCE, and CSE. This method can be used for the identification and quantification of andrographolide, myricetin, and brazilin in herbal raw materials or herbal products containing these three extracts.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1437</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Eem Masaenah&lt;sup&gt;1,2&lt;/sup&gt;, Berna Elya&lt;sup&gt;1,*&lt;/sup&gt;, Heri Setiawan&lt;sup&gt;1&lt;/sup&gt;, Zahra Fadhilah&lt;sup&gt;1&lt;/sup&gt;, Varda Arianti&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, Universitas Indonesia, Depok 16424, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Sekolah Tinggi Teknologi Industri dan Farmasi, Bogor 16151, West Java, INDONESIA.&lt;/p&gt;
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