<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Oscar Herrera-Calderon</style></author><author><style face="normal" font="default" size="100%">Renan Dilton Hañari-Quispe</style></author><author><style face="normal" font="default" size="100%">Johnny Aldo Tinco-Jayo</style></author><author><style face="normal" font="default" size="100%">Josefa Bertha Pari-Olarte</style></author><author><style face="normal" font="default" size="100%">Luz Josefina Chacaltana-Ramos</style></author><author><style face="normal" font="default" size="100%">Eddie Loyola-Gonzales</style></author><author><style face="normal" font="default" size="100%">Melva Iparraguirre-Meza</style></author><author><style face="normal" font="default" size="100%">Mildred Hilda Cóndor- Privat</style></author><author><style face="normal" font="default" size="100%">Beatriz Lilian Galdos-Vadillo</style></author><author><style face="normal" font="default" size="100%">Jenny Mendoza-Vilcahuaman</style></author><author><style face="normal" font="default" size="100%">Rossibel Juana Muñoz-de-la-Torre</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pasuchaca (Geranium ruizii Hieron.): A Medicinal Plant of the Geraniaceae Family with Hypoglycemic Effect on Alloxan-Induced Hyperglycemia in Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antidiabetic drugs</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidants</style></keyword><keyword><style  face="normal" font="default" size="100%">Geranium ruizii</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal therapy</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Pasuchaca</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">315-321</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The current study aims to evaluate the hypoglycemic effect of the hydroalcoholic extract of &lt;em&gt;Geranium ruizii &lt;/em&gt;on alloxan-induced hyperglycemia in albino mice. &lt;strong&gt;Material and Methods: &lt;/strong&gt;&lt;em&gt;Geranium ruizii&lt;/em&gt; was collected in Huancayo, Junin, Peru. A phytochemical analysis was carried out to confirm the chemical groups. In the pharmacological study, hyperglycemia was induced with alloxan at doses of 170 mg/kg in male albino mice, animals with blood sugar levels above 250 mg/dL were included in the protocol. Mice were randomized into five groups (I: Alloxan 170 mg/Kg; II, III and IV (&lt;em&gt;Geranium ruizii &lt;/em&gt;extract: 50; 150 and 300 mg/Kg body weight); and V: glibenclamide, 5mg/Kg B.W. Results: Phytochemical analysis confirmed the presence of tannins, flavonoids, alkaloids, terpenes, saponins and phenolic compounds. It is observed that at doses of 50, 150 and 300 mg/kg reduced blood glucose at 14 days of treatment. &lt;strong&gt;Conclusion: &lt;/strong&gt;The hypoglycemic effect of the hydroalcoholic extract of &lt;em&gt;Geranium ruizii&lt;/em&gt;, administered orally in mice with alloxan-induced hyperglycemia was effective with 150 mg/Kg body weight.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">315</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Oscar Herrera-Calderon&lt;sup&gt;1,*&lt;/sup&gt;, Renan Dilton Hañari-Quispe&lt;sup&gt;2&lt;/sup&gt;, Johnny Aldo Tinco-Jayo&lt;sup&gt;3&lt;/sup&gt;, Josefa Bertha Pari- Olarte&lt;sup&gt;4&lt;/sup&gt;, Luz Josefina Chacaltana-Ramos&lt;sup&gt;4&lt;/sup&gt;, Eddie Loyola-Gonzales&lt;sup&gt;5&lt;/sup&gt;, Melva Iparraguirre-Meza&lt;sup&gt;6&lt;/sup&gt;, Mildred Hilda Cóndor-Privat&lt;sup&gt;6&lt;/sup&gt;, Beatriz Lilian Galdos-Vadillo&lt;sup&gt;6&lt;/sup&gt;, Jenny Mendoza- Vilcahuaman&lt;sup&gt;7&lt;/sup&gt;, Rossibel Juana Muñozde-la-Torre&lt;sup&gt;7&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, Bromatology and Toxicology, Faculty of Pharmacy and Biochemistry, Universidad Nacional Mayor de San Marcos, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Clinical Pathology Laboratory, Faculty of Veterinary Medicine and Zootechnics, Universidad Nacional del Altiplano, Puno, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Human Medicine, Faculty of Health Sciences, Universidad Nacional de San Cristóbal de Huamanga, Ayacucho, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biochemistry, Universidad Nacional San Luis Gonzaga, Ica, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Pharmaceutical Sciences, Faculty of Pharmacy and Biochemistry, Universidad Nacional San Luis Gonzaga, Ica, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Professional school of obstetrics, Faculty of health sciences, Universidad Peruana Los Andes, Huancayo, Junin, PERU.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Academic Department of obstetrics, Faculty of Health Sciences, Universidad Nacional de Huancavelica, Huancavelica, PERU.&lt;/p&gt;
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