<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rohan S. Phatak</style></author><author><style face="normal" font="default" size="100%">Chitra C. Khanwelkar</style></author><author><style face="normal" font="default" size="100%">Somnath M. Matule</style></author><author><style face="normal" font="default" size="100%">Kailas D. Datkhile</style></author><author><style face="normal" font="default" size="100%">Anup S. Hendre</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antihyperlipidemic Activity of Murraya koenigii Leaves Methanolic and Aqueous Extracts on Serum Lipid Profile of High Fat-Fructose Fed Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Atherogenic index</style></keyword><keyword><style  face="normal" font="default" size="100%">High fat-fructose diet</style></keyword><keyword><style  face="normal" font="default" size="100%">Hyperlipidemia</style></keyword><keyword><style  face="normal" font="default" size="100%">lipid profile</style></keyword><keyword><style  face="normal" font="default" size="100%">Murraya Koenigii</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">836-841</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Dyslipidemia has been considered as one of coronary risk factors contributing to the cardiovascular diseases. The beneficial effects of &lt;em&gt;Murraya koenigii&lt;/em&gt; leaf on HFFD induced hyperlipidemia in rats has been very less reported in the recent review of literature.&lt;strong&gt; Aim and Objectives:&lt;/strong&gt; To study the hypolipidemic activity of &lt;em&gt;Murraya koenigii&lt;/em&gt; leaves on the serum lipid profile in HFFD rat model. &lt;strong&gt;Material and Methods:&lt;/strong&gt; Thirty-six rats of either sex were randomly divided into six groups of six animals each. HFFD was fed p.o to all rats from Groups I, II, IV, V and VI except Group III throughout the period of 14 weeks. Group III rats received normal diet and water &lt;em&gt;ad libitum &lt;/em&gt;only. Group I, II, IV and V were treated respectively with AEMK (200 mg/kg/day, p. o), MEMK (200 mg/kg/day, p. o), MET (50 mg/kg/day, p. o) and ATO (10 mg/kg/day, p. o). On the last day of experimental study, blood was collected by retro-orbital puncture method. BSL and lipid profile were assessed. &lt;strong&gt;Results: &lt;/strong&gt;Elevated levels of TC, TG, LDL-C, VLDL-C and diminished level of HDL-C were observed in group VI. &lt;em&gt;Murraya koenigii&lt;/em&gt; leaves extract exhibited significant hypolipidemic effect on serum TC and LDL-C in rats owing to its hypocholesterolemic properties. AIP was highly significant in both of AEMK and MEMK extracts. &lt;strong&gt;Conclusion:&lt;/strong&gt; Results of the present study have suggested that the antihyperlipidemic activity of &lt;em&gt;Murraya koenigii&lt;/em&gt; leaves leading to decrease in serum lipid parameters mainly TC, LDL-C along with atherogenic risk might be due to its presence of bioactive compounds.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">836</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Rohan S. Phatak&lt;sup&gt;1,*&lt;/sup&gt;, Chitra C. Khanwelkar&lt;sup&gt;1&lt;/sup&gt;, Somnath M. Matule&lt;sup&gt;1&lt;/sup&gt;, Kailas D. Datkhile&lt;sup&gt;2&lt;/sup&gt;, Anup S. Hendre&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, Krishna Institute of Medical Sciences, Karad-415110, Maharashtra, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Molecular Biology and Genetics, Krishna Institute of Medical Sciences, Karad-415110, Maharashtra, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biochemistry, Krishna Institute of Medical Sciences, Karad-415110, Maharashtra, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sujith S</style></author><author><style face="normal" font="default" size="100%">Priya MN</style></author><author><style face="normal" font="default" size="100%">Deepa CK</style></author><author><style face="normal" font="default" size="100%">Usha PTA</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Characterization of the Anthelmintic Activity of Murraya koenigii (Linn.)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anthelmintic</style></keyword><keyword><style  face="normal" font="default" size="100%">Egg hatch assay</style></keyword><keyword><style  face="normal" font="default" size="100%">Haemonchus contortus</style></keyword><keyword><style  face="normal" font="default" size="100%">Larval motility assay</style></keyword><keyword><style  face="normal" font="default" size="100%">Murraya Koenigii</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">s100-s103</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; To identify the most potent sub fractions(s) of the different extracts of the leaves of &lt;em&gt;Murraya koenigii&lt;/em&gt; for the anthelmintic property. &lt;strong&gt;Methods:&lt;/strong&gt; The dried leaves were subjected to soxhlet extraction using methanol, fractionated using n-hexane, chloroform, n-butanol and water. Preliminary phytochemical analysis was done using standard techniques. The potent fractions were subjected to TLC and the appropriate solvent was selected for flash chromatographic separation of the extract. The sub fractions were tested for their anthelmintic activity in vitro using egg hatch assay and larval motility assay on&lt;em&gt; Haemonchus contortus&lt;/em&gt; eggs and the most potent fraction was found out. &lt;strong&gt;Results:&lt;/strong&gt; Phytochemical analysis revealed the presence of phenolic, tannins and saponins in all extracts and the effect of the extracts could be due to these components. On TLC, toluene: ethyl acetate in 9:1 ratio was found to be the best mobile phase for hexane and chloroform fractions whereas cyclohexane: ethyl acetate at 6:4 was found suitable for butanol fraction. Of the sub fractions (SF), SF 3 and 11 of chloroform fraction showed better ovicidal activity whereas SF 2,6,7,32 and 37 showed best larvicidal activity. The larvae that were used for testing the larvicidal activity, were found to be sluggishly motile after half an hour incubation with the extract and were progressively dead on a dose dependent manner. &lt;strong&gt;Conclusion&lt;/strong&gt;: The chloroform extract of &lt;em&gt;Murraya koenigii&lt;/em&gt; and its sub fractions 2, 3,6, 7, 11, 32 and 37 possessed good anthelmintic activity and the isolation of active molecules is necessary for development of a novel anthelmintic.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s100</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sujith S&lt;sup&gt;1*&lt;/sup&gt;, Priya MN&lt;sup&gt;2&lt;/sup&gt;, Deepa CK&lt;sup&gt;3&lt;/sup&gt;, Usha PTA&lt;sup&gt;4 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Assistant Professor, Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Mannuthy, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt; 2&lt;/sup&gt;Assistant Professor, Department of Veterinary Parasitology, College of Veterinary and Animal Sciences, Mannuthy, Kerala, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Assistant Professor, Department of Veterinary Parasitology, College of Veterinary and Animal Sciences, Pookode, Kerala, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Professor and Head, Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Mannuthy, Kerala, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mrinal Sanaye</style></author><author><style face="normal" font="default" size="100%">Nimisha Pagare</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of antioxidant effect and anticancer activity against human glioblastoma (U373MG) cell lines of Murraya Koenigii</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anticancer</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Flow cytometry..</style></keyword><keyword><style  face="normal" font="default" size="100%">Glioblastoma</style></keyword><keyword><style  face="normal" font="default" size="100%">Murraya Koenigii</style></keyword><keyword><style  face="normal" font="default" size="100%">SRB assay</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">220-225</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Aim: &lt;/strong&gt;The main aim of the study was to screen the ethanolic (EEMK) and methanolic (MEMK) extracts of &lt;em&gt;Murraya koenigii &lt;/em&gt;(MK&lt;em&gt;) &lt;/em&gt;leaves and their alkaloid fractions (EFMK and MFMK) for their &lt;em&gt;in vitro &lt;/em&gt;anti-oxidant and anticancer activity against U373MG cell lines. &lt;strong&gt;Methods: &lt;/strong&gt;&lt;em&gt;In vitro &lt;/em&gt;antioxidant activity of extracts and fractions was determined by DPPH Radical assay, Reducing power assay, Inhibition of lipid peroxidation, Superoxide radical scavenging assay and Hydroxyl radical scavenging assay. Cytotoxic effect of MK extracts and fractions was evaluated by performing Sulphorhoda&amp;shy;mine B (SRB) assay and Flow cytometry analysis on U373MG cell lines. &lt;strong&gt;Results: &lt;/strong&gt;Extracts and fractions of MK were found to possess significant antioxidant activity. In SRB colorimetric assay, the efficacy of MK against U373MG cell line was observed due to reduced viability of U373MG cells. Dose dependent significant increase in the percentage of dead cells was also observed. MEMK exhibited significant cytotoxicity than EEMK where&amp;shy;as EFMK and MFMK were not found to be significantly cytotoxic against U373MG cell lines. Flow cytometry analysis revealed that the effective extract MEMK induces cell death in human glioblastoma cells through apoptotic mode of action. &lt;strong&gt;Conclusion: &lt;/strong&gt;The observed anticancer activity of &lt;em&gt;Murraya koenigii &lt;/em&gt;may be due to its antioxidant potential.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">220</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Mrinal Sanaye and Nimisha Pagare &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacology, 23 Jote Joy Building, Rambhau Salgaonkar Marg, Cuffe Parade, Colaba, Mumbai: 400005, INDIA.&lt;/p&gt;
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