<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gornganok Piboonpol</style></author><author><style face="normal" font="default" size="100%">On-Anong Somsap</style></author><author><style face="normal" font="default" size="100%">Wanita Panthong</style></author><author><style face="normal" font="default" size="100%">Penporn Sujiwattanarat</style></author><author><style face="normal" font="default" size="100%">Anussara Kamnate</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antimicrobial and Antioxidant Activities of Phanera aureifolia (K.Larsen &amp; S.S.Larsen) Bandyop., P.P.Ghoshal &amp; M.K.Pathak Leaf Ethanolic Extracts</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoid compound</style></keyword><keyword><style  face="normal" font="default" size="100%">P.P.Ghoshal &amp; M.K.Pathak</style></keyword><keyword><style  face="normal" font="default" size="100%">Phanera aureifolia (K.Larsen &amp; S.S.Larsen) Bandyop.</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolic compound</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">365-369</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Natural antioxidants and antimicrobial agents are abundantly found in medicinal plants. &lt;strong&gt;Objective: &lt;/strong&gt;This study evaluated the antimicrobial and antioxidant activities of two colors from &lt;em&gt;Phanera aureifolia &lt;/em&gt;(K.Larsen &amp;amp; S.S.Larsen) Bandyop., P.P.Ghoshal &amp;amp; M.K.Pathak leaf ethanolic extracts including gold and green leaves. &lt;strong&gt;Method:&lt;/strong&gt; To assess antimicrobial efficacy, the agar well diffusion technique was analyzed. Scanning electron microscopy (SEM) was utilized to investigate the ultrastructural alterations in MRSA caused by leaf extracts. DPPH assay was used to assess antioxidant activity. The total amounts of phenolic compounds and flavonoids were evaluated through the Folin-Ciocalteu and aluminum chloride colorimetric techniques, respectively. The statistical analysis using an independent t-test. &lt;strong&gt;Results: &lt;/strong&gt;Both extracts demonstrated activity against &lt;em&gt;Pseudomonas aeruginosa &lt;/em&gt;TISTR146, &lt;em&gt;Micrococcus luteus&lt;/em&gt; TISTR884, &lt;em&gt;Staphylococcus aureus&lt;/em&gt; TISTR517 and Methicillin-resistant &lt;em&gt;S. aureus &lt;/em&gt;142 (MRSA142). Their activity against &lt;em&gt;M. luteus&lt;/em&gt; TISTR884 was the highest observed. The MIC of both extracts against MRSA were 10 mg/ml. SEM analysis revealed that the cells exhibited noticeable enlargement and swelling compared to untreated MRSA cells. Extract from the green leaves of Gold leaf Bauhinia showed greater radical scavenging activity, higher total phenolic and flavonoid contents, compared to those from the golden leaves. &lt;strong&gt;Conclusions: &lt;/strong&gt;The findings show that the extract from the green leaves of Gold leaf Bauhinia possess higher antioxidant potential compared to those from the golden leaves. In addition, both extracts exhibited antimicrobial activity, especially against MRSA.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">365</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Gornganok Piboonpol &lt;sup&gt;1*&lt;/sup&gt;, On-anong Somsap&lt;sup&gt;2&lt;/sup&gt;, Wanita Panthong&lt;sup&gt;2&lt;/sup&gt;, Penporn Sujiwattanarat&lt;sup&gt;2&lt;/sup&gt;, Anussara Kamnate&lt;sup&gt;3&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;1Department of Pharmacology, Faculty of medicine, Princess of Naradhiwas University, Narathiwat, Thailand&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;2Department of Biochemistry, Faculty of medicine, Princess of Naradhiwas University, Narathiwat, Thailand&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;3Department of Anatomy, Faculty of medicine, Princess of Naradhiwas University, Narathiwat, Thailand&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ajayi Adebimpe Oluwabunmi</style></author><author><style face="normal" font="default" size="100%">Aruwa Christiana Eleojo</style></author><author><style face="normal" font="default" size="100%">Sabiu Saheed</style></author><author><style face="normal" font="default" size="100%">Akinyosoye Felix Akinsola</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Cheminformatic and in vitro Bioprospection of Capsicum Annuum L. Metabolites as DNA Gyrase B Inhibitors</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Capsicum annuum</style></keyword><keyword><style  face="normal" font="default" size="100%">Computational analysis.</style></keyword><keyword><style  face="normal" font="default" size="100%">Gyrase B</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemicals</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">726-737</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Capsicum species are known in food and trado-medicinal uses for maladies management due their rich content of phytochemicals, but with little work done on &lt;em&gt;in silico&lt;/em&gt; bioprospection of its volatilome. Objectives: This study targeted chemometric profiling, virtual bioprospection of potential lead metabolites in 2 &lt;em&gt;Capsicum annuum&lt;/em&gt; L. fruit variants’ (green and red) to identify lead gyrase B inhibitors (GBIs) and provide new mechanistic insights. &lt;strong&gt;Methods: &lt;/strong&gt;Metabolites were profiled using Gas Chromatography-Mass Spectrometry (GC-MS), and quantitative phytochemical assays. Extracts antioxidant (DPPH, ABTS, FRAP) and antibacterial (susceptibility testing) activities were also determined.&lt;em&gt; In silico&lt;/em&gt; [docking, pharmacokinetics, DFT] analyses were used to identify and predict chemical features of potential lead GBIs key to extracts molecular mechanism of action. &lt;strong&gt;Results: &lt;/strong&gt;Mass spectral analysis identified hydrocarbons, fatty acid and other derivatives. Quantitative phytochemical analysis showed flavonoids, cardiac glycosides and alkaloids. The green&lt;em&gt; C. annuum&lt;/em&gt; extract had better antioxidative action, while extracts of both green and red variant showed similar antimicrobial profiles against resistant bacterial pathogens. &lt;em&gt;In silico &lt;/em&gt;highest docking scores were observed for [1-Ethyloctyl) cyclohexane (-6.6 kcal/mol)] and dibutyl phthalate (-6.4 kcal/mol). All lead GBIs had desirable pharmacokinetics in line with the Lipinski rule of 5, and chemical reactivity properties. &lt;strong&gt;Conclusion:&lt;/strong&gt; &lt;em&gt;In silico&lt;/em&gt; and &lt;em&gt;in vitro &lt;/em&gt;methods combination provided robust metabolomic profiling. The identified lead &lt;em&gt;C. &lt;/em&gt;&lt;em&gt;annuum&lt;/em&gt;-based natural GBIs contribute to the bioactivity profile and molecular mechanism of action of fractions. The study provided a first-hand report on natural GBIs derivable from Capsicum fruits which could be exploited in formulations for non-food and pharmaceutical applications.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">726</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ajayi Adebimpe Oluwabunmi&lt;sup&gt;1&lt;/sup&gt;, Aruwa Christiana Eleojo&lt;sup&gt;2*&lt;/sup&gt;, Sabiu Saheed&lt;sup&gt;2&lt;/sup&gt;, Akinyosoye Felix Akinsola&lt;sup&gt;1 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Microbiology, School of Life Sciences, Federal University of Technology,&amp;nbsp;Akure, PMB 704, Ondo State, NIGERIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, PO Box 1334, Durban 4000, SOUTH AFRICA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Shahad Myasar Alfaris</style></author><author><style face="normal" font="default" size="100%">Rasha Khalid Dhahir</style></author><author><style face="normal" font="default" size="100%">Amina Mudhafar Al-Nima</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Preparation, Evaluation of Propolis Extract Gel and exploring its Antioxidant, Antimicrobial Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Carbopol-934</style></keyword><keyword><style  face="normal" font="default" size="100%">Poloxamer-407</style></keyword><keyword><style  face="normal" font="default" size="100%">Propolis</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">675-681</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Propolis is a wax-like resin which is produced by different types of bees by mixing resinous secretions of plants with beeswax and other products of bees' metabolism. However, this natural product contains a group of compounds that are responsible for various propolis activities including antimicrobial, anticancer, antioxidant, antiviral, and others. This study aims to prepare different gel formulae that contain various concentrations of propolis extract using two different polymers and to evaluate their physical properties, antioxidant, and antimicrobial activities. &lt;strong&gt;Method: &lt;/strong&gt;Propolis was extracted depending on the hydroalcoholic method; six different gel formulae (P-1 to P-6) were prepared with different concentrations of propolis extract (0.5, 1, and 1.5%) using two different polymers; carbopol-934 and poloxamer-407, in concentrations of 0.5 and 25% respectively. The formulae were evaluated physically for their visual appearance, pH, viscosity, spreadability, and physiological compatibility with the skin. The anti-microbial activities were investigated by well diffusion method against various bacterial species including &lt;em&gt;Staphylococcus aureus&lt;/em&gt; (gram+), Pseudomonas aeruginosa (gram-), Enterococcus fecalis (gram+) and against one fungal species which is Candida albicans. Also, the antioxidant activity was determined utilizing 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay. Finally, a stability test was carried out for the chosen formula.&lt;strong&gt; Results:&lt;/strong&gt; The six formulae (P-1 to P-6) were successfully prepared and evaluated and they were acceptable in their physical appearance and consistency, pH reading was in the range of 5.33±0.08 to 5.72±0.02 (p&amp;gt;0.05), a study of the skin irritation revealed no undesirable side effect, while the viscosity was in the range of 128.99±0.07 to 248.54±1.04 Pa.s (p&amp;gt;0.05), also the carbopol-934 containing formulae revealed good spreadability (1.495±0.075 to 5.15±0.35 mg.cm/s, p&amp;gt;0.05), in comparison to poloxamer-407 containing ones. Both carbopol-934 and poloxamer-407 containing formulae exhibited antimicrobial activity but the P-3 formula had the largest inhibition zone against &lt;em&gt;C. Albicans &lt;/em&gt;(16.1mm), and only P-2, P-5 and P-6 were active against &lt;em&gt;pseudomonas aeruginosa&lt;/em&gt; (12mm in all), while P-2 had the largest inhibition zone against&lt;em&gt; enterococcus fecalis&lt;/em&gt; (13.2 mm), P-2 and P-5 showed the largest activity against &lt;em&gt;staphylococcus aureus&lt;/em&gt; (15.5 and 14.6 mm respectively). The carbopol-934-containing formulae exhibited higher antioxidant activity than those with poloxamer-407, and the best-calculated IC50 belonged to P-2 (1.19 mg/ml). &lt;strong&gt;Conclusion:&lt;/strong&gt; All the prepared formulae showed antimicrobial and antioxidant activities with some controversial results. However, P-2 (1% propolis extract and 0.5% carbopol-934), was active against all types of the tested microorganism, and had the best-calculated IC50, in addition to that it was a stable formula.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">675</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Shahad Myasar Alfaris*, Rasha Khalid Dhahir, Amina Mudhafar Al-Nima&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Pharmaceutics, College of Pharmacy, University of Mosul, Mosul, IRAQ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sueptrakool Wisessombat</style></author><author><style face="normal" font="default" size="100%">Malatee Tayeh</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">In vitro Wound Healing Potential and Antimicrobial Activity of Clerodendrum Inerme Leave Extracts</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Clerodendrum inerme</style></keyword><keyword><style  face="normal" font="default" size="100%">Keratinocytes</style></keyword><keyword><style  face="normal" font="default" size="100%">Scratch assay</style></keyword><keyword><style  face="normal" font="default" size="100%">Wound Healing</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1542-1548</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt;&lt;em&gt; Clerodendrum inerme &lt;/em&gt;is a medicinal plant which exhibited many pharmacological effects. However, wound healing property of this plant has not been investigated. &lt;strong&gt;Objective&lt;/strong&gt;: The present study was designed to evaluate wound healing and antimicrobial activities of &lt;em&gt;C. inerme&lt;/em&gt; leaves using the &lt;em&gt;in vitro &lt;/em&gt;model with Human keratinocytes (HaCaT). &lt;strong&gt;Methods&lt;/strong&gt;: Cytotoxicity and wound healing effects were determined by MTT and scratch wound healing assay. Antimicrobial activities against cutaneous flora and clinical isolates of bacteria were investigated by broth microdilution assay. &lt;strong&gt;Results:&lt;/strong&gt; The results showed that the water extract of &lt;em&gt;C. inerme&lt;/em&gt; leaves did not exhibit cytotoxic effects on HaCaT cells, while ethanol extracts at higher concentrations significantly decreased cell growth with an IC&lt;sub&gt;50&lt;/sub&gt; value of 386.8 ± 87.1 μg/mL. The water extract and the lowest concentration (6.25 μg/mL) of the ethanol extract significantly increased percentage of wound closure compared with the untreated group. The water and ethanol extracts of &lt;em&gt;C. inerme&lt;/em&gt; displayed a broad spectrum of antibacterial activity, inhibiting growth of Staphylococcus aureus, &lt;em&gt;Staphylococcus.epidermidis,&lt;/em&gt; &lt;em&gt;Escherichia coli,&lt;/em&gt; and &lt;em&gt;Pseudomonas aeruginosa.&lt;/em&gt; The water extract displayed remarkable activity against methicillin-resistant S. aureus with MIC and MBC values ranging from 0.39 to 1.56 μg/mL. Notably, it provided stronger antibacterial activity than vancomycin and also showed antifungal activity against&lt;em&gt; C. albicans. &lt;/em&gt;&lt;strong&gt;Conclusion:&lt;/strong&gt; This study confirms the potential of &lt;em&gt;C. inerme &lt;/em&gt;leaves for wound healing and antimicrobial therapy and supports the continued utilization of &lt;em&gt;C. inerme&lt;/em&gt; leaves in traditional medicine. Further studies are needed to clarify the molecular mechanisms through which it exerts such biological effects.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1542</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sueptrakool Wisessombat&lt;sup&gt;1&lt;/sup&gt;, Malatee Tayeh&lt;sup&gt;1,2,&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Food Technology and Innovation Center of Excellence, Walailak University, Nakhon Si Thammarat 80160, THAILAND.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nguyen Van Chuyen</style></author><author><style face="normal" font="default" size="100%">Nguyen Hong Son</style></author><author><style face="normal" font="default" size="100%">Pham Van Hien</style></author><author><style face="normal" font="default" size="100%">Dang Truong Giang</style></author><author><style face="normal" font="default" size="100%">Ho Ba Ngoc Minh</style></author><author><style face="normal" font="default" size="100%">Ngo Thi Tuyet Mai</style></author><author><style face="normal" font="default" size="100%">Chu Van Men</style></author><author><style face="normal" font="default" size="100%">Ho Anh Son</style></author><author><style face="normal" font="default" size="100%">Vu Binh Duong</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A New Ursane-Type Triterpene from the Fermented Shallot Allium Ascalonicum</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">24-Acetonideclethric acid</style></keyword><keyword><style  face="normal" font="default" size="100%">3</style></keyword><keyword><style  face="normal" font="default" size="100%">Allium ascalonicum</style></keyword><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Saponin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">01-07</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;3,24-acetonideclethric acid &lt;strong&gt;(1), &lt;/strong&gt;a new ursane-type triterpene, and four known compounds including ursolic acid &lt;strong&gt;(2),&lt;/strong&gt; randiasaponin IV &lt;strong&gt;(3),&lt;/strong&gt; ilekudinoside W &lt;strong&gt;(4)&lt;/strong&gt; and (25S)-1β,3β,24β- trihydroxyspirost-5-en 1-O-α-L-rhamnopyranosyl-(1→2)- α-L-arabinopyranoside &lt;strong&gt;(5), &lt;/strong&gt;and were isolated from the fermented shallot &lt;em&gt;Allium ascalonicum&lt;/em&gt;. Their structures were determined by analysis of HR-ESI-MS, NMR spectral data, as well as comparison with those reported in the literature. All of the saponins (3-5) exhibited antimicrobial activity against three strains &lt;em&gt;Staphylococcus aureus, Escherichia coli,&lt;/em&gt; and &lt;em&gt;Candida albicans &lt;/em&gt;with IC&lt;sub&gt;50&lt;/sub&gt; values in the range from 89.49 ± 2.24 to 95.71 ± 3.86 μM.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">01</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Nguyen Van Chuyen#, Nguyen Hong Son#, Pham Van Hien, Dang Truong Giang, Ho Ba Ngoc Minh, Ngo Thi Tuyet Mai, Chu Van Men, Ho Anh Son*, Vu Binh Duong*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Vietnam Military Medical University, 160 Phung Hung, Ha Dong District, Hanoi, VIETNAM.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;#These authors contributed equally to this work.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mohsen S Al-Omar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Phytochemical Analysis, Antioxidant, and Anti-Microbial Activities of Suaeda vermiculata n-Hexane Extract in Comparison to the Plant's Hydrodistilled Volatile Oil</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">n-hexane extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Suaeda vermiculata</style></keyword><keyword><style  face="normal" font="default" size="100%">Volatile oil</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">853-859</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; &lt;em&gt;Suaeda vermiculata&lt;/em&gt;, a halophyte found in central Saudi Arabia, used as a remedy for jaundice, liver diseases, and viral infection. &lt;strong&gt;Study aim: &lt;/strong&gt;Chemical identification and biological evaluation for the n-hexane extract of &lt;em&gt;S. vermiculata&lt;/em&gt;.&lt;strong&gt; Methods: &lt;/strong&gt;An assay of the antimicrobial and antioxidant potentials and contents of the volatile oil and n-hexane extract of the plant’s aerial parts were analyzed through GC-MS analysis.&lt;strong&gt; Results: &lt;/strong&gt;A total of 24 constituents representing 73.74 % of the n-hexane extract were identified wherein bornyl acetate, γ-elemene, and phytol were major ratio. The n-hexane extract inhibited DPPH-radicals inhibitions at 27% efficiency at 10 mg/ml concentration which was lower than the volatile oil DPPH-reactivity. The antimicrobial activity of n-hexane extract was relatively weaker than the volatile oil, except against &lt;em&gt;Candida albicans&lt;/em&gt; that showed IZD values of 19 mm with MIC value at 5.2 mg/ml for the volatile oil while IZD value of 26 mm and MIC at 4.7 mg/ml was observed for the n-hexane extract. &lt;strong&gt;Conclusion:&lt;/strong&gt; Despite high extractive value, the n-hexane as a solvent is not recommended for extraction as the oxygenated-terpenic components, considered responsible for antioxidant and antimicrobial activities were not fully extracted. The n-hexane extract which showed potent inhibition of &lt;strong&gt;C. albicans&lt;/strong&gt; can be a source for further investigation for bioactivities of its constituents.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">853</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Mohsen S. Al-Omar&lt;sup&gt;1,2,&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, Buraydah, 51452, KINGDOM OF SAUDI ARABIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Medicinal Chemistry and Pharmacognosy Department, Faculty of Pharmacy, JUST, Irbid 22110, JORDAN.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Faiza MOULAI-HACENE</style></author><author><style face="normal" font="default" size="100%">Mokhtaria Yasmina BOUFADI</style></author><author><style face="normal" font="default" size="100%">Soumia KEDDARI</style></author><author><style face="normal" font="default" size="100%">Abdelkader HOMRANI</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Chemical Composition and Antimicrobial Properties of Elettaria cardamomum Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Chemical composition</style></keyword><keyword><style  face="normal" font="default" size="100%">Elettaria cardamomum</style></keyword><keyword><style  face="normal" font="default" size="100%">Pathogenic strains</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1058-1063</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Cardamom, also known as&lt;em&gt; Elettaria cardamomum,&lt;/em&gt; a venerated perennial herb like the &quot;Queen of Spices&quot; belongs to the Zingiberaceae family. She holds various pharmacological activities due to its phytochemicals it contains such as; phenols, tannins, terpenoids, flavonoids, sterols. &lt;strong&gt;Methods: &lt;/strong&gt;The study included the determination of the chemical composition of&lt;em&gt; Elettaria cardamomum&lt;/em&gt; ethanolic extract (EEC) by HPLC/UV and evaluated their antimicrobial potential against ten pathogenic reference strains using two complementary techniques: the method of diffusion from solid discs and the determination of minimum inhibitory concentrations (MIC). &lt;strong&gt;Results:&lt;/strong&gt; The results obtained from chemical identification of the EEC showed the presence of polyphenolic acids (rosmarinic acid, caffeic acid, ferulic acid, etc.) and many flavonoids (kaempferol, chrysin, galangin, pinocembrine, quercetin, etc.). The results of the antimicrobial effect showed that the extract reacted positively on almost all the microbial strains tested. The EEC extract significantly inhibited the growth of microbial strains, with a broader antimicrobial spectrum with extensive action with inhibitory zones between 8 and 33 mm in diameter. Thus, this extract revealed a dose-dependent antimicrobial activity on these microbial strains used. However, the inhibitory potential of the cardamom extract was variable compared to their MIC ranging from 6.25 to 12.5 mg of dry extract/mL. Therefore, the strains least susceptible to EEC are &lt;em&gt;Bacillus subtilis, Escherichia coli, Aspergillus niger&lt;/em&gt; and&lt;em&gt; Candida albicans&lt;/em&gt;. &lt;strong&gt;Conclusion: &lt;/strong&gt;This activity is due to the phenolic compounds produced by the EEC extract. This extract can be used for the development of plant medicines against microbial infections and fungal infestations.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1058</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Faiza MOULAI-HACENE&lt;sup&gt;1&lt;/sup&gt;, Mokhtaria Yasmina BOUFADI&lt;sup&gt;2,3,&lt;/sup&gt;*, Soumia KEDDARI&lt;sup&gt;2&lt;/sup&gt;, Abdelkader HOMRANI&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Laboratory of Sciences and Techniques of Animal Production (LSTPA), Faculty of Natural Sciences and Life, Abdelhamid Ibn Badis University, Mostaganem, ALGERIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of Beneficial Microorganisms, Functional Food and Health (LMBAFS), Faculty of Natural Sciences and Life, Abdelhamid Ibn Badis University, Mostaganem, ALGERIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, Université Libre de Bruxelles, Brussels, BELGIUM.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vasanth MP</style></author><author><style face="normal" font="default" size="100%">KG Purushotham</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Screening of Phytochemical Analysis and In vitro Bioactive of Polyherbal Formulation</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">FTIR</style></keyword><keyword><style  face="normal" font="default" size="100%">HR-LCMS</style></keyword><keyword><style  face="normal" font="default" size="100%">Phyto chemical</style></keyword><keyword><style  face="normal" font="default" size="100%">Secondary metabolites</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1525-1533</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Plants have the capability to synthesize various forms of phytochemical compounds as secondary metabolites. &lt;strong&gt;Method: &lt;/strong&gt;In the present investigation phytochemicals such as alkaloids, tannins, glycosides, carbohydrates, reducing sugar, proteins, saponins, flavanoids, phenols, terpenoids and phytosterols were detected in polyherbal formulation &lt;em&gt;A. marmelos, G. glabra and R. centrifolia. &lt;/em&gt;&lt;strong&gt;Results:&lt;/strong&gt; The Total flavonoid, steroids, alkaloids and phenolic content was observed from fruit, root and pettles1.40mg QE/g DE, 12.14mg BE/g DE, 14.40mg AE/g DE and 99.33mg GAE/g DE. FTIR spectrum of the polyherbal sample revealed 5 major peaks at 2919.40 cm&lt;sup&gt;-1&lt;/sup&gt;, 2357.62 cm&lt;sup&gt;-1&lt;/sup&gt;, 1150.56 cm&lt;sup&gt;-1&lt;/sup&gt;, 1076.22 cm&lt;sup&gt;-1&lt;/sup&gt; and 1015.64 cm&lt;sup&gt;-1&lt;/sup&gt;. The antibacterial activity was maximum zone of inhibition (19 mm) was recorded in S. aureus strain and minimum zone of inhibition (5mm) was observed in S.mutans strain. The antioxidant study maximum and minimum scavenging DPPH, NOR, H2O2 and SOD activities (%) of 62.28, 53.68, 39.67 &amp;amp; 43.98 at 5 mg/ml and 39.88, 36.49, 5.9 and 34.94 at 1mg/ml was recorded. The polyherbal sample exhibited significant albumin denaturation, proteinase inhibitory, membrane stabilization and lipid peroxidation inhibitory activities as the maximum inhibition of 46.53%, 36.7%, 51.9% and 64.71% was observed at 500 μg/ml. &lt;strong&gt;Conclusion:&lt;/strong&gt; Hence the present studies indicate good antibacterial, antioxidant and anti-inflammatory activities from the medicinal plants, &lt;em&gt;A. marmelos, G. glabra and R. centrefolia &lt;/em&gt;proves the possibility of its utilization as an additional potent source medicinal uses.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1525</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Vasanth MP, KG Purushotham* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Biotechnology, Dr. M.G.R EDUCATIONAL AND RESEARCH INSTITUTE, Chennai-600095, Tamilnadu, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ahmed Al-Ghamdi</style></author><author><style face="normal" font="default" size="100%">Thanaa Elkholy</style></author><author><style face="normal" font="default" size="100%">Shahd Abuhelal</style></author><author><style face="normal" font="default" size="100%">Hatim Al-Abbadi</style></author><author><style face="normal" font="default" size="100%">Dina Qahwaji</style></author><author><style face="normal" font="default" size="100%">Nahlaa Khalefah</style></author><author><style face="normal" font="default" size="100%">Hanaan Sobhy</style></author><author><style face="normal" font="default" size="100%">Mohammad Abu-Hilal</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antibacterial and Antifungal Activity of Jojoba Wax Liquid (Simmondsia chinensis)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial</style></keyword><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Jojoba oil</style></keyword><keyword><style  face="normal" font="default" size="100%">Minimum inhibitory concentration (MIC)</style></keyword><keyword><style  face="normal" font="default" size="100%">Simmondsia chinesisis</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">191-194</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;strong&gt;Introduction&lt;/strong&gt;: Plants are a rich source of bioactive compounds. &lt;em&gt;Simmondsia chinensis&lt;/em&gt;, also known as Jojoba, is the sole member the Simmondsiaceae’s family and has been known traditionally for many medical uses. Objectives: Herein we evaluate the value of crude jojoba oil (J.O) as an antimicrobial agent in vitro.&lt;strong&gt; Methods&lt;/strong&gt;: J.O was tested for potential antimicrobial activity against &lt;em&gt;Bacillus subtilis&lt;/em&gt;, &lt;em&gt;Staphylococcus aureus, Proteus vulgaris, P. mirabilis, Salmonella typhimurium, Escherichia coli, Pseudomonas aeruginosa, Candida albicans and Asperigillus flavus&lt;/em&gt;. &lt;strong&gt;Results&lt;/strong&gt;: Our results did not show any effect on fungi or yeast. However, a significant antibacterial activity was observed against &lt;em&gt;B. subtilis, S. aureus, P. vulgaris, P. mirabilis&lt;/em&gt;. A high activity was observed for J.O at Minimum inhibitory concentration (MIC) level of 12.5 mg/ml. Interestingly, &lt;em&gt;S. typhimurium, E. coli and Ps. aeruginosa&lt;/em&gt; were found to be highly resistant. &lt;strong&gt;Conclusion&lt;/strong&gt;: Our findings suggest that J.O may have a medicinal potential as natural antibacterial agent.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">191</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Ahmed Al-Ghamdi&lt;sup&gt;1,&lt;/sup&gt;*, Thanaa Elkholy&lt;sup&gt;2&lt;/sup&gt;, Shahd Abuhelal&lt;sup&gt;3&lt;/sup&gt;, Hatim Al-Abbadi&lt;sup&gt;4&lt;/sup&gt;, Dina Qahwaji&lt;sup&gt;5&lt;/sup&gt;, Nahlaa Khalefah&lt;sup&gt;5&lt;/sup&gt;, Hanaan Sobhy&lt;sup&gt;6&lt;/sup&gt;, Mohammad Abu-Hilal&lt;sup&gt;7&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, SAUDI ARABIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Al-Azhar University, Al Mokhaym Al Daem, Cairo, Cairo Governorate, EGYPT.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Institute of Pharmaceutical Science, Faculty of Life Sciences and Medicine, King’s College London, Franklin-Wilkins building, 150 Stamford Street, London SE1 8NH, UNITED KINGDOM.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;4&lt;/sup&gt;Consultant General Laparoscopic Surgeon, King Abdulaziz University, University Hospital, Director of Experimental Surgery Unit, KFMRC*, Jeddah, SAUDI ARABIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;5&lt;/sup&gt;Departments of Clinical Nutrition, Faculty of Applied Medical Sciences, King Abdul-Aziz University, Jeddah, SAUDI ARABIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;6&lt;/sup&gt;Head of Pharmacology Unit, -Biochemical, and Toxicology and Food Deficiency.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;7&lt;/sup&gt;Consultant Hepatobiliary and Pancreatic Surgery, University Hospital, Southampton University, UNITED KINGDOM.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Abreu MM</style></author><author><style face="normal" font="default" size="100%">Nobrega P De A</style></author><author><style face="normal" font="default" size="100%">Sales PF</style></author><author><style face="normal" font="default" size="100%">Oliveira FRDe</style></author><author><style face="normal" font="default" size="100%">Nascimento AA</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antimicrobial and Antidiarrheal Activities of Methanolic Fruit Peel Extract of Pouteria caimito</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Abiu</style></keyword><keyword><style  face="normal" font="default" size="100%">Antidiarrheal activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Sapotaceae</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">944-950</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;em&gt; &lt;/em&gt;&lt;/strong&gt;&lt;em&gt;Pouteria caimito&lt;/em&gt; is a native Amazonian fruit specie, popularly known as &quot;abiu&quot;, that belongs to the Sapotaceae family. It has a wide popular use to relieve diarrhea, cough, fever and inflammation, among other purposes. However, few reports in the scientific literature deal with its phytochemical composition and biological activity. This study aimed to evaluate the antidiarrheal and antimicrobial activity of &lt;em&gt;Pouteria caimito&lt;/em&gt; fruit peel extract. &lt;strong&gt;Methods:&lt;/strong&gt; The antidiarrheal activity was evaluated in mice, using modulation models of normal defecation, cathartic agent-induced diarrhea and stimulated intestinal transit. Antimicrobial activity was, in turn, analyzed against strains of gram-positive and gram-negative bacteria (&lt;em&gt;E. coli, S. epidermidis, S. aureus, Klebsiella pneumonie, E. faecalis and Salmonella tiphy&lt;/em&gt;) through the determination of the minimum inhibitory concentration (MIC) by the microdilution in broth method. Results: This study showed that there was no antidiarrheal activity in the experimental models analyzed and that the methanolic extract of &lt;em&gt;P. caimito&lt;/em&gt; (MEPC) can positively modulate normal defecation. Regarding the antimicrobial activity, the crude extract and the ethyl acetate fraction presented a satisfactory action against most of the strains evaluated except for &lt;em&gt;Enterococcus faecalis&lt;/em&gt; and &lt;em&gt;Salmonella tiphy&lt;/em&gt;. Conclusions: The MEPC did not present any measurable antidiarrheal activity, but more possibly a laxative effect. The extract and acetate fraction showed antimicrobial activity against strains of gram-positive and gram-negative bacteria. The activity of the crude extract was more potent than the results obtained by the use of acetate fractions; the fractions with lower polarity did not present any relevant antimicrobial activity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">944</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Abreu MM&lt;sup&gt;1,&lt;/sup&gt;*, Nobrega P De A&lt;sup&gt;2&lt;/sup&gt;, Sales PF&lt;sup&gt;2&lt;/sup&gt;, Oliveira FRDe&lt;sup&gt;3&lt;/sup&gt;, Nascimento AA&lt;sup&gt;1 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Federal University of Amapá, Postgraduate Program in Pharmaceutical Sciences, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Federal University of Amapá, Postgraduate Program in Health Sciences, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Pharmaceutical Sciences, Laboratory of Quality Control, Bromatology and Microbiology, BRAZIL.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Camilla Filippi dos Santos Alves</style></author><author><style face="normal" font="default" size="100%">Pauline Cordenonsi Bonez</style></author><author><style face="normal" font="default" size="100%">Marcia de Souza Ebling</style></author><author><style face="normal" font="default" size="100%">Camila Casagrande</style></author><author><style face="normal" font="default" size="100%">Litiane Freitas</style></author><author><style face="normal" font="default" size="100%">Carolina Dolwitsch</style></author><author><style face="normal" font="default" size="100%">Fernanda Pires</style></author><author><style face="normal" font="default" size="100%">Michele Rorato Sagrillo</style></author><author><style face="normal" font="default" size="100%">Gerson Fernandes de Brum</style></author><author><style face="normal" font="default" size="100%">Marli Matiko Anraku de Campos</style></author><author><style face="normal" font="default" size="100%">Roberto Christ Vianna Santos</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antimicrobial, Cyto and Genotoxic Activities of Equisetum hyemale</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Cytotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Equisetum hyemale</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolic compounds</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1563-1571</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The popular use of natural products has great benefits for the health of the human population. In this study we highlight &lt;em&gt;Equisetum hyemale&lt;/em&gt;, belonging to the phylum Sphenophyta and the family Equisetaceae. Popularly, the stems of this plant are used for their diuretic, digestive, anti-anemic, and anti-inflammatory properties. Given this context, and the fact that the growth of antimicrobial resistance is a serious problem for global public health, this plant could be used as an alternative, to increase our therapeutic arsenal. Therefore, it is important to more clearly elucidate the complex structures present in plants, because these substances are mainly responsible for their beneficial and/or toxic effects. Thus, the objective of this study was evaluate the antimicrobial activity, cytotoxic and genotoxic potential of the phenolic compounds separately. The substances luteolin, ferulic acid and coumarin were identified at high concentrations by ultra-high performance chromatography-electrospray ionization-mass spectrometry (UPLC-ESI-MS). Antimicrobial activity was elucidated through microdilution in broth; the phenolic compounds were able to inhibit the visible growth of the standard bacterial strains at low concentrations. Cytotoxicity was evaluated by MTT and genotoxicity was analysed through cellular damage using a Comet assay; the results showed that it did not present cytoxicity or genotoxicity at the corresponding concentrations. With this, we suggest that &lt;em&gt;E. hyemale&lt;/em&gt; may be an alternative for the treatment of infections by microorganisms that are resistant to synthetic drugs.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1563</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Camilla Filippi dos Santos Alves&lt;sup&gt;1,&lt;/sup&gt;*, Pauline Cordenonsi Bonez&lt;sup&gt;2&lt;/sup&gt;, Marcia de Souza Ebling&lt;sup&gt;3&lt;/sup&gt;, Camila Casagrande&lt;sup&gt;2&lt;/sup&gt;, Litiane Freitas&lt;sup&gt;2&lt;/sup&gt;, Carolina Dolwitsch&lt;sup&gt;5&lt;/sup&gt;, Fernanda Pires&lt;sup&gt;5&lt;/sup&gt;, Michele Rorato Sagrillo&lt;sup&gt;4&lt;/sup&gt;, Gerson Fernandes de Brum&lt;sup&gt;4&lt;/sup&gt;, Marli Matiko Anraku de Campos&lt;sup&gt;1&lt;/sup&gt;, Roberto Christ Vianna Santos&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Clinical and Toxicological Analysis, Mycobacteriology Laboratory, Universidade Federal de Santa Maria (UFSM), Santa Maria, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Oral Microbiology Research Laboratory, Microbiology and Parasitology Department, Universidade Federal de Santa Maria (UFSM), Santa Maria, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Graduate Program in Nanoscience, Franciscan University (UFN), Santa Maria, RS, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Cell Culture Laboratory, Universidade Franciscana (UFN), Santa Maria, BRAZIL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Graduate Program in Pharmaceutical Sciences, Universidade Federal de Santa Maria (UFSM), Santa Maria, BRAZIL.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hamdoon Abdelhamid Mohammed</style></author><author><style face="normal" font="default" size="100%">Mohsen Saleh Al-Omer</style></author><author><style face="normal" font="default" size="100%">Adel Mohammed Ahmed</style></author><author><style face="normal" font="default" size="100%">Nadia Elbialy Hashish</style></author><author><style face="normal" font="default" size="100%">Hasan Meshal Alsaedi</style></author><author><style face="normal" font="default" size="100%">Suliman Abdulaziz Alghazy</style></author><author><style face="normal" font="default" size="100%">Ahmed Abdelfattah Hafez Abdellatif</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comparative Study for the Volatile Oil Constituents and Antimicrobial Activity of Rhanterium epapposum Oliv. Growing in Qassim, Saudi Arabia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Comparative study</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oils</style></keyword><keyword><style  face="normal" font="default" size="100%">Hot extraction. Cold extraction</style></keyword><keyword><style  face="normal" font="default" size="100%">Rhanterium epapposum</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">195-199</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt;&lt;em&gt; Rhanterium epapposum&lt;/em&gt; is an herbaceous plant widely distributed in the Gulf region and used by Bedouins as antiseptic for wounds, skin infections and in gastrointestinal disturbances. &lt;strong&gt;Aim:&lt;/strong&gt; The study aimed to compare the results obtained from volatile oil analysis of &lt;em&gt;R. epapposum &lt;/em&gt;growing in Buraydah, Qassim with reported data of the same plant growing in Riyadh “Al-Majmaah” and Northern border region of Saudi Arabia. Both cold and hot extracts of the &lt;em&gt;R. epapposum &lt;/em&gt;were used to find the best extraction method to be adopted as an antimicrobial agent. Methods: Volatile oils were distillated using Clevenger apparatus and analyzed by GC-MS. The plant powder was extracted by cold maceration and hot contentious extraction methods. Furthermore, antimicrobial activity was conducted using the agar diffusion method.&lt;strong&gt; Results:&lt;/strong&gt; The hydro-distillation of &lt;em&gt;R. epapposum&lt;/em&gt; growing in Qassim region yielded 0.5 % w/w of the total volatile oils. Moreover, forty-three compounds of 97.68% of the volatile oil components were identified while modephene, caryophyllene, linalyl acetate and epizonarene were the major components of volatile oils. Nevertheless, the volatile oils diversity and concentrations were found to be different in &lt;em&gt;R. epapposum &lt;/em&gt;growing in Buraydah, as compared with the plant growing in Riyadh and the northern border region of Saudi Arabia which almost due to the differences in the environmental condition. Among all extracts, ethyl acetate hot extract showed the best inhibition to bacterial strains while fugal strain &lt;em&gt;Candida albicans&lt;/em&gt; growth was better inhibited by hot &lt;em&gt;n&lt;/em&gt;-hexane extract. &lt;strong&gt;Conclusion:&lt;/strong&gt; Volatile oils were active against all microbial strains. Hot extracts were more active against bacterial strains while the opposite effects were found against &lt;em&gt;Candida albicans &lt;/em&gt;which was generally inhibited by the cold extracts.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">195</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Hamdoon Abdelhamid Mohammed&lt;sup&gt;1,2,*&lt;/sup&gt;, Mohsen Saleh Al-Omer&lt;sup&gt;1&lt;/sup&gt;, Adel Mohammed Ahmed&lt;sup&gt;1&lt;/sup&gt;, Nadia Elbialy Hashish&lt;sup&gt;1,6&lt;/sup&gt;, Hasan Meshal Alsaedi&lt;sup&gt;3&lt;/sup&gt;, Suliman Abdulaziz Alghazy&lt;sup&gt;3&lt;/sup&gt;, Ahmed Abdelfattah Hafez Abdellatif&lt;sup&gt;4,5&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Medicnal Chemistry and Pharmacognosy department, Faculty of Pharmacy, Qassim University, Buraydah, 51452, KINGDOM OF SAUDI ARABIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Pharmacognosy department, Faculty of Pharmacy, Al-Azhar University, Cairo, EGYPT.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Pharm. D. student, Faculty of Pharmacy, Qassim University, Buraydah, 51452, KINGDOM OF SAUDI ARABIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;4&lt;/sup&gt;Pharmaceutics and Industrial pharmacy department, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, EGYPT.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;5&lt;/sup&gt;Pharmaceutics department, Faculty of Pharmacy, Qassim University, Buraydah, 51452, KINGDOM OF SAUDI ARABIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Pharmacognosy , College of Pharmacy, Mansoura University, Egypt).&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ritesh Kumar Sharma</style></author><author><style face="normal" font="default" size="100%">Anjana Goel</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Identification of Phytoconstituents in Lawsonia inermis Linn. Leaves Extract by GC-MS and their Antibacterial Potential</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">1</style></keyword><keyword><style  face="normal" font="default" size="100%">4 Napthelenedione</style></keyword><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Lawsone</style></keyword><keyword><style  face="normal" font="default" size="100%">Lawsonia inermis Linn</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Methanol extract</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">1101-1108</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Plant extracts contains multiple active constituents which leads to the production of new drugs from plants and chemicals derived from various parts of plants. The objective of present study was to investigate the GC-MS analysis and antibacterial activity of &lt;em&gt;L. inermis&lt;/em&gt; leaves extracts. &lt;strong&gt;Material and Methods:&lt;/strong&gt; Crude methanol extract and its fractions were tested for the presence of active phytochemicals and GC-MS analysis of hexane; ethyl acetate and aqueous methanol fractions was performed. Antimicrobial activity against six bacterial strain&amp;rsquo;s &lt;em&gt;Escherichia coli, Staphylococcus aureus, Bacillus subtelis, Salmonella typhi, Klebsiella&lt;/em&gt; and &lt;em&gt;Pseudomonas aeruginosa&lt;/em&gt; was also tested. &lt;strong&gt;Results:&lt;/strong&gt; Phytochemical screening of extract confirmed the presence of carbohydrates, glycosides, quinones, steroids and phenol. In GC-MS chromatograms, 56, 108 and 19 peaks were obtained and out of these, 13, 17 and 7 compounds were identified in hexane, ethyl acetate and aqueous methanol fractions, respectively. &lt;strong&gt;Conclusion:&lt;/strong&gt; For best of our knowledge in &lt;em&gt;L.&amp;nbsp;inermis&lt;/em&gt; leaves extract, Celidoniol and Vitamin E has not been reported earlier in hexane fractions. While 2, 3 dihydrobenzo furan, 1-H indole -1, 3 (2H)-dione, 1 (3H)-Isobenzofuranone, 1H Isoindole-1, 3 (2H) Dione, Napthelene, 2 ethoxy, 2 (4H) Benzofuranone, Vitamin E, Benzene, 1 isocyano 4 methyl are also identified for the first time in ethyl acetate fraction. Also, in aq. Methanol fraction 1(3H)-isobenzofuranone, Squalene and Vit E were not previously identified. Highest antibacterial activity was confirmed in crude methanol extract which might be due to all the antibacterial compounds present in its fractions. The present study helped in identifying phytoconstituents present in the extract and its fractions which are responsible for various biological and antibacterial activities.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">xx1101</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ritesh Kumar Sharma&lt;sup&gt;1,&lt;/sup&gt;*, Anjana Goel&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Ph.D. Scholar, Department of Biotechnology, IAH, GLA University, Mathura, Uttar Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Associate Professor, Department of Biotechnology, IAH, GLA University, Mathura, Uttar Pradesh, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Islamudin Ahmad</style></author><author><style face="normal" font="default" size="100%">Neneng Siti Silfi Ambarwati</style></author><author><style face="normal" font="default" size="100%">Arif Lukman</style></author><author><style face="normal" font="default" size="100%">Muhammad Amir Masruhim</style></author><author><style face="normal" font="default" size="100%">Laode Rijai</style></author><author><style face="normal" font="default" size="100%">Abdul Mun’im</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">In vitro Antimicrobial Activity Evaluation of Mangrove Fruit (Sonneratia caseolaris L.) Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Agar disc diffusion method</style></keyword><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Mangrove fruit</style></keyword><keyword><style  face="normal" font="default" size="100%">Sonneratia caseolaris L.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/531</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">598-601</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Mangrove fruit (&lt;em&gt;Sonneratia caseolaris&lt;/em&gt; L) from Sonneratiaceae family known with local name &amp;ldquo;Pidada Merah&amp;rdquo; has bioactive components. The present study aimed to evaluate the antimicrobial activity of this plant. &lt;strong&gt;Method:&lt;/strong&gt; The sample was macerated using methanol, the antimicrobial activity assay was performed using agar disc diffusion method against &lt;em&gt;Escherichia coli&lt;/em&gt; ATTC9637, &lt;em&gt;Staphylococcus aureus&lt;/em&gt; ATTC6538, and &lt;em&gt;Candida albicans&lt;/em&gt; ATTC10231. &lt;strong&gt;Results:&lt;/strong&gt; Antimicrobial activity of Mangrove fruit methanol extract were obtained the optimum concentration of &lt;em&gt;S. aureus&lt;/em&gt; of 80%, &lt;em&gt;E. coli&lt;/em&gt; of 15%, and &lt;em&gt;C. albicans&lt;/em&gt; of 30%. &lt;strong&gt;Conclusion:&lt;/strong&gt; based on the results, the sample has antimicrobial properties, and this is a preliminary data for further study.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt; &lt;em&gt;Sonneratia caseolaris L&lt;/em&gt;, Mangrove fruit, Antimicrobial activity, Agar disc diffusion method.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">598</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Islamudin Ahmad&lt;sup&gt;1*&lt;/sup&gt;, Neneng Siti Silfi Ambarwati&lt;sup&gt;2&lt;/sup&gt;, Arif Lukman&lt;sup&gt;1&lt;/sup&gt;, Muhammad Amir Masruhim&lt;sup&gt;3&lt;/sup&gt;, Laode Rijai&lt;sup&gt;4&lt;/sup&gt;, Abdul Mun&amp;rsquo;im&lt;sup&gt;5 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Sciences, Faculty of Pharmacy, Mulawarman University, Samarinda, East Kalimanta, 75119, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Engineering, Universitas Negeri Jakarta, East Jakarta, 13220, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Chemistry Education, Faculty of Teacher Training and Education Sciences, Mulawarman University, Samarinda, East Kalimantan, 75119, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Pharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Mulawarman University, Samarinda, East Kalimantan, 75119, INDONESIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Indonesia, Depok, West Java, 16424, INDONESIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Lubna Abu-Niaaj</style></author><author><style face="normal" font="default" size="100%">Ibrahim Katampe</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Isolation and Characterization of Flavones from Artemisia monosperma</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidants</style></keyword><keyword><style  face="normal" font="default" size="100%">Artemisia monosperma</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavones</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">1018-1023</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; &lt;em&gt;Artemisia monosperma&lt;/em&gt; (Delile) is a green aromatic shrub that grows widely in the deserts of Middle East, Africa and China. This plant is commonly used in folk medicine as a remedy of a wide range of illness including gastrointestinal disorders, inflammation, diabetes and microbial infection. The different categories of the secondary metabolites identified from Artemisia species are recognized for their biological activities as antioxidants, anti-inflammatory and antimicrobial compounds. &lt;strong&gt;Objective:&lt;/strong&gt; This study aims to isolate new flavonoids from &lt;em&gt;A. monosperma&lt;/em&gt; that might have potential biological activities thus be translated into pharmaceutical uses. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Air-dried &lt;em&gt;A. monosperma&lt;/em&gt; extraction was done using different organic solvents. The methanolic extract was selected for isolation of flavonoids using column chromatography and thin layer chromatography. The chemical structures of the isolated flavones determined based on spectroscopic analysis of ultraviolet, mass and nuclear magnetic resonance spectra.&lt;strong&gt; Results:&lt;/strong&gt; Nine flavone aglycones were isolated and identified from the methanolic extract; four of which are reported for the first time from &lt;em&gt;A. monosperma&lt;/em&gt;. These include: 5-Hydroxy-3',4', 6,7-tetramethoxyflavone; 3',5-dihydroxy-4',6,7-trimethoxyflavone (eupatorin); 5,6-dihydroxy-4',7-dimethoxyflavone(ladanein); and 2',4',5-trihydroxy-5',6,7&amp;ndash; trimethoxyflavone (arcapillin). The remaining five flavones were previously identified from this plant as : 4',5-Dihydroxy-3',6,7-tri-methoxyflavone(cirsilineol);5,7-dihydroxy-3',4',6-trimethoxyflavone (eupatilin);4',5,7-trihydroxy-3',6-dimethoxyflavone(jaceosidin);4',5-dihydroxy-6,7-dimethoxy- flavone (circimaritin) and 4',5,7-trihydroxy-6-methoxyflavone (hispidulin). In addition, two acetophenone derivatives were isolated from fractions yielded selected flavones and these were identified as 4-hydroxyacetophenone and 3-(2-hydroxymethyl-2-buten-4-yl)-4-hydroxyaceto- phenone. &lt;strong&gt;Conclusion:&lt;/strong&gt; This successful isolation of these natural flavonoids from &lt;em&gt;A. monosperma&lt;/em&gt; can contribute further to the evaluation of bioactive compounds against disorders including but not limited to inflammatory associated disorders and microbial infections.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1018</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Lubna Abu-Niaaj* Ibrahim Katampe&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Natural Sciences, Central State University, 1400 Brush Row Road, Wilberforce, OH 45384, USA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Candra Irawan</style></author><author><style face="normal" font="default" size="100%">Foliatini</style></author><author><style face="normal" font="default" size="100%">Hanafi</style></author><author><style face="normal" font="default" size="100%">Lilis Sulistiawaty</style></author><author><style face="normal" font="default" size="100%">Maman Sukiman</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Volatile Compound Analysis using GC-MS, Phytochemical Screening and Antioxidant Activities of the Husk of “Julang-Jaling” (Archidendron bubalinum (Jack) I.C Nielsen) from Lampung, Indonesia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Archidendron bubalinum (Jack) I.C Nielsen</style></keyword><keyword><style  face="normal" font="default" size="100%">GC-MS</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemicals</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/403</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">92-98</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; &amp;ldquo;Julang-jaling&amp;rdquo; (&lt;em&gt;Archidendron bubalinum&lt;/em&gt; (Jack) I.C Nielsen) fruits are commonly used as traditional food and in the treatment of blood sugar and heart disease. However, the research about the phytochemicals of the parts of this plants and their bioactivity was rare. &lt;strong&gt;Objective:&lt;/strong&gt; The recent study was aimed to analyze volatile compounds in the extract of &amp;ldquo;julang-jaling&amp;rdquo; husks and evaluate their antioxidant and antimicrobial activities. &lt;strong&gt;Material and methods:&lt;/strong&gt; The extraction was conducted using &lt;em&gt;n-&lt;/em&gt;hexane, ethyl acetate, and methanol as extracting agent. The phytochemical assay was performed for all extracts, and followed by volatile compound analysis using GC-MS. The antioxidant assay was performed using DPPH method, and the antimicrobial activity was conducted using agar disc diffusion method. &lt;strong&gt;Results:&lt;/strong&gt; The phytochemical assay showed that all extracts of &amp;ldquo;julang-jaling&amp;rdquo; husks contain various phytoconstituents having potential bioactivity. All extracts exhibit antioxidant activity with different level of activity depend on the type of extract. The IC&lt;sub&gt;50&lt;/sub&gt; value were 273.57 ppm, 324.913 ppm, 735 ppm, for ethyl acetate, methanol and &lt;em&gt;n-&lt;/em&gt;hexane, respectively. All extracts were able to inhibit the growth of &lt;em&gt;Bacillus cereus&lt;/em&gt;, with the highest antimicrobial activity was gained for ethyl acetate extract. Both ethyl acetate and methanolic extract have antimicrobial activity toward &lt;em&gt;E. coli&lt;/em&gt;, but no extracts yield positive results for &lt;em&gt;Aspergillus flavus&lt;/em&gt; and &lt;em&gt;Aspergillus niger&lt;/em&gt;. &lt;strong&gt;Conclusion:&lt;/strong&gt; GC-MS analysis revealed the presence of hexadecanoic acids and their ester form in all extract, which might largely contribute in the antioxidant and antimicrobial activity.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">92</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Candra Irawan&lt;sup&gt;1&lt;/sup&gt;, Foliatini&lt;sup&gt;1&lt;/sup&gt;*, Hanafi&lt;sup&gt;2&lt;/sup&gt;, Lilis Sulistiawaty&lt;sup&gt;1&lt;/sup&gt; and Maman Sukiman&lt;sup&gt;3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Analytical Chemistry Polytechnic of AKA Bogor, Bogor 16158, INDONESIA&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Food Industrial Quality Assurance Polytechnic of AKA Bogor, Bogor 16158, INDONESIA&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Industrial Waste Treatment Polytechnic of AKA Bogor, Bogor 16158, INDONESIA&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Swapna Gurrapu</style></author><author><style face="normal" font="default" size="100%">Estari Mamidala</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">In vitro Antibacterial Activity of Alkaloids Isolated from Leaves of Eclipta alba Against Human Pathogenic Bacteria</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Agarwell diffusion</style></keyword><keyword><style  face="normal" font="default" size="100%">Alkaloid</style></keyword><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Broth micro-dilution assay.</style></keyword><keyword><style  face="normal" font="default" size="100%">Eclipta alba</style></keyword><keyword><style  face="normal" font="default" size="100%">Human pathogenic bacteria</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">/files/PJ-9-4/10.5530pj.2017.4.91</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">573-577</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;The susceptibility of five human pathogenic bacterial species to an alkaloids isolated from the leaves of this plant was screened using the agar well diffusion and broth micro-dilution assay. The purity of isolated alkaloids was checked by TLC and qualitative phytochemical analysis and total alkaloids were quantified. In the present study, the inhibitory action of the alkaloid was found to increase with an increase in concentration against all bacterial strains. The maximum zone of inhibition was observed at the concentration of 500 &amp;mu;g/ml against all the bacteria. In this study, the &lt;em&gt;S. aureus &lt;/em&gt;and &lt;em&gt;E. coli&lt;/em&gt; are the more susceptible than the other selected human pathogenic bacteria. Based on the observations, &lt;em&gt;E. alba&lt;/em&gt; appears to be a valuable source for antimicrobial properties and helps to produce antimicrobial agents to treat human pathogenic infections. &lt;strong&gt;Context:&lt;/strong&gt; Different parts of Eclipta alba crude extracts are used traditionally for the treatment of several diseases of liver, skin and stomach. &lt;strong&gt;Aims:&lt;/strong&gt; To study the &lt;em&gt;in vitro&lt;/em&gt; antimicrobial activity of alkaloids isolated from &lt;em&gt;E. alba&lt;/em&gt; against human pathogenic bacteria. &lt;strong&gt;Settings and Design:&lt;/strong&gt; The susceptibility of five human pathogenic bacterial species to an alkaloids isolated from the leaves of this plant was screened using the agar well diffusion and broth micro-dilution assay. &lt;strong&gt;Methods and Material:&lt;/strong&gt; The purity of isolated alkaloids was checked by TLC and qualitative phytochemical analysis and total alkaloids were quantified. Agar-well diffusion and Broth micro-dilution methods were selected to assess the antimicrobial activity. &lt;strong&gt;Statistical analysis used:&lt;/strong&gt; One-way analysis of variance (ANOVA) was used to determine statistical significance. &lt;strong&gt;Results:&lt;/strong&gt; In the present study, the inhibitory action of the alkaloid was found to increase with an increase in concentration against all bacterial strains. The maximum zone of inhibition was observed at the concentration of 500 &amp;mu;g/ml against all the bacteria. In this study, the &lt;em&gt;S. aureus&lt;/em&gt; and &lt;em&gt;E. coli&lt;/em&gt; are the more susceptible than the other selected human pathogenic bacteria. &lt;strong&gt;Conclusion:&lt;/strong&gt; Based on the observations, &lt;em&gt;E. alba&lt;/em&gt; appears to be a valuable source for antimicrobial properties and helps to produce antimicrobial agents to treat human pathogenic infections.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">573</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Swapna Gurrapu and Estari Mamidala&lt;sup&gt;* &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;em&gt;Infectious Diseases Research Lab, Department of Zoology, Kakatiya University, Warangal- 506009, telangana State, INDIA.&lt;/em&gt;&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Pradeep Kumar Sharma</style></author><author><style face="normal" font="default" size="100%">Vijender Singh</style></author><author><style face="normal" font="default" size="100%">Mohammed Ali</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Chemical Composition and Antimicrobial Activity of Fresh Rhizome Essential Oil of Zingiber Officinale Roscoe</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal,</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antimicrobial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Chemical composition</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential oil</style></keyword><keyword><style  face="normal" font="default" size="100%">GC-MS analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Zingiber officinale.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">185-190</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Zingiber officinale &lt;/em&gt;Roscoe (Zingiberaceae) is a rhizomatous perennial herb found in tropical Asia. It is extensively used worldwide as a spice, flavoring agent and herbal remedy for cold, throat and chest&amp;nbsp;infections and cough. The present study was carried out to analyse an essential oil from the fresh rhizomes of &lt;em&gt;Z. officinale &lt;/em&gt;of Ghaziabad region and to evaluate its antimicrobial activity. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;The fresh rhizomes were hydrodistilled to get the essential oil which was analysed by GC and GC-MS techniques. The oil was evaluated for antimicrobial activity by disc diffusion method. &lt;strong&gt;Results and Discussion: &lt;/strong&gt;The essential oil was characterized by high percentage of sesquiterpenes (66.66%), monoterpenes (17.28%) and aliphatic compounds (13.58%). The predominant sesquiterpene was zingiberene (46.71%) followed by valencene (7.61%), &amp;beta;-funebrene (3.09%) and selina-4(14),7(11)-diene (1.03%). The major monoterpenes were characterized as citronellyl &lt;em&gt;n&lt;/em&gt;-butyrate (19.34%), &amp;beta;-phellandrene (3.70%), camphene (2.59%) and &amp;alpha;-pinene (1.09%). The essential oil exhibited significant antimicrobial activity against &lt;em&gt;Bacillus subtilis, Staphylococcus aureus&lt;/em&gt;, &lt;em&gt;Escherichia&lt;/em&gt; &lt;em&gt;coli, Pseudomonas aeruginosa&lt;/em&gt;, &lt;em&gt;Candida albicans &lt;/em&gt;and &lt;em&gt;Aspergillus niger&lt;/em&gt;. &lt;strong&gt;Conclusion: &lt;/strong&gt;The essential oil mainly contained a large number of sesquiterpenes and monoterpenes and exhibited significant antimicrobial activity against pathogenic microorganisms.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">185</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align:justify&quot;&gt;&lt;strong&gt;Pradeep Kumar Sharma&lt;sup&gt;1&lt;/sup&gt;*, Vijender Singh&lt;sup&gt;2&lt;/sup&gt;, Mohammed Ali&lt;sup&gt;3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align:justify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacy, R V Northland Institute, Greater Noida, G B Nagar, U.P. 203207, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align:justify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;B B S College of Pharmacy, Greater Noida, G B Nagar, U.P. 201306, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align:justify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Phytochemistry Research Laboratory, Faculty of Pharmacy, Jamia Hamdard, Hamdard Nagar, New Delhi 110062, INDIA.&lt;/p&gt;
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