<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gargi Nag</style></author><author><style face="normal" font="default" size="100%">Sukriti Das</style></author><author><style face="normal" font="default" size="100%">Susmita Das</style></author><author><style face="normal" font="default" size="100%">Suvra Mandal</style></author><author><style face="normal" font="default" size="100%">Bratati De</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant, anti-acetylcholinesterase and anti-glycosidase properties of three species of Swertia, their xanthones and amarogentin: A comparative study</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acetylcholinesterase</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant.</style></keyword><keyword><style  face="normal" font="default" size="100%">Glycosidase</style></keyword><keyword><style  face="normal" font="default" size="100%">Swertia Sp.</style></keyword><keyword><style  face="normal" font="default" size="100%">Xanthone</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">27th Dec, 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">117-123</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align:justify&quot;&gt;&lt;strong&gt;Aim: &lt;/strong&gt;The aim of the study was to analyze the antioxidant, anti-amylase, anti-glucosidase and antiacetylcholinesterase (anti-AChE) properties of the leafy shoots of three Indian species of &lt;em&gt;Swertia&lt;/em&gt; e.g. &lt;em&gt;Swertia chirata&lt;/em&gt; and its substitutes &lt;em&gt;Swertia bimaculata,&lt;/em&gt; and Swertia decussata, their xanthones and amarogentin. &lt;strong&gt;Methods: &lt;/strong&gt;Antioxidant activity of the methanolic extracts of leafy shoots was measured in terms of DPPH, superoxide and nitric oxide radical scavenging activities as well as metal chelating properties. Enzyme inhibitory properties were measured using AChE, &amp;alpha;-amylase and &amp;alpha;-glucosidase respectively. Five xanthones bellidifolin (1), swerchirin (2), decussatin (3), mangiferin (4) and 1-hydroxy-3,5,8-trimethoxy xanthone (6) and one iridoid, amarogentin (5) were isolated from &lt;em&gt;Swertia chirata&lt;/em&gt;. The activities of the isolated components were compared. &lt;strong&gt;Results: &lt;/strong&gt;&lt;em&gt;Swertia chirata&lt;/em&gt; exhibited best antioxidant and anti-AChE properties than the other two species. The plants also possessed &amp;alpha;-glucosidase inhibitory properties but weak &amp;alpha;-amylase inhibitory activity. Highest activities were observed in &lt;em&gt;Swertia chirata&lt;/em&gt;. We report here, for the first time, the antioxidant, anti-AChE and anti-glycosidase activity of 1-hydroxy-3,5,8-trimethoxy xanthone. This xanthone had strongest DPPH radical scavenging activity and anti-AChE property. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results suggest the beneficial effects of the xanthones of &lt;em&gt;Swertia chirata&lt;/em&gt;. But further study should be carried out to prove the efficacy &lt;em&gt;in vivo. &lt;/em&gt;&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Key words:&lt;/strong&gt;&lt;em&gt; Swertia Sp.,&lt;/em&gt; Xanthone, Glycosidase, Acetylcholinesterase, Antioxidant.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">117</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align:justify&quot;&gt;&lt;strong&gt;Gargi Nag&lt;sup&gt;1&lt;/sup&gt;, Sukriti Das&lt;sup&gt;1&lt;/sup&gt;, Susmita Das&lt;sup&gt;1&lt;/sup&gt;, Suvra Mandal&lt;sup&gt;2&lt;/sup&gt;, Bratati De&lt;sup&gt;1*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align:justify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Phytochemistry and Pharmacognosy Research Laboratory, Centre of Advanced Study, Department of Botany, University of Calcutta, 35 Ballygunge Circular Road, Kolkata 700019, India&lt;/p&gt;&lt;p style=&quot;text-align:justify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Chemistry, National Research Institute of Ayurvedic Drug Development, Bidhannagar, Kolkata 700091, India&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gargi Nag</style></author><author><style face="normal" font="default" size="100%">Sukriti Das</style></author><author><style face="normal" font="default" size="100%">Susmita Das</style></author><author><style face="normal" font="default" size="100%">Bratati De</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">Suvra Mandal</style></author></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant, anti-acetylcholinesterase and anti-glycosidase properties of three species of Swertia, their xanthones and amarogentin: A comparative study</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acetylcholinesterase</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant.</style></keyword><keyword><style  face="normal" font="default" size="100%">Glycosidase</style></keyword><keyword><style  face="normal" font="default" size="100%">Swertia Sp.</style></keyword><keyword><style  face="normal" font="default" size="100%">Xanthone</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Mar-Apr 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">117-123</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Aim:&lt;/strong&gt; The aim of the study was to analyze the antioxidant, anti-amylase, anti-glucosidase and antiacetylcholinesterase (anti-AChE) properties of the leafy shoots of three Indian species of Swertia e.g. Swertia chirata and its substitutes Swertia bimaculata, and Swertia decussata, their xanthones and amarogentin. &lt;strong&gt;Methods:&lt;/strong&gt; Antioxidant activity of the methanolic extracts of leafy shoots was measured in terms of DPPH, superoxide and nitric oxide radical scavenging activities as well as metal chelating properties. Enzyme inhibitory properties were measured using AChE, &amp;alpha;-amylase and &amp;alpha;-glucosidase respectively. Five xanthones bellidifolin (1), swerchirin (2), decussatin (3), mangiferin (4) and 1-hydroxy-3,5,8-trimethoxy xanthone (6) and one iridoid, amarogentin (5) were isolated from Swertia chirata. The activities of the isolated components were compared. &lt;strong&gt;Results:&lt;/strong&gt; Swertia chirata exhibited best antioxidant and anti-AChE properties than the other two species. The plants also possessed &amp;alpha;-glucosidase inhibitory properties but weak &amp;alpha;-amylase inhibitory activity. Highest activities were observed in Swertia chirata. We report here, for the first time, the antioxidant, anti-AChE and anti-glycosidase activity of 1-hydroxy-3,5,8-trimethoxy xanthone. This xanthone had strongest DPPH radical scavenging activity and anti-AChE property. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results suggest the beneficial effects of the xanthones of Swertia chirata. But further study should be carried out to prove the efficacy in vivo&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">117</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Gargi Nag&lt;sup&gt;1,&lt;/sup&gt; Sukriti Das&lt;sup&gt;1&lt;/sup&gt;, Susmita Das&lt;sup&gt;1&lt;/sup&gt;, Suvra Mandal&lt;sup&gt;2&lt;/sup&gt;, Bratati De&lt;sup&gt;1*&lt;/sup&gt; &lt;/strong&gt;&lt;sup&gt;1&lt;/sup&gt;Phytochemistry and Pharmacognosy Research Laboratory, Centre of Advanced Study, Department of Botany, University of Calcutta, 35 Ballygunge Circular Road, Kolkata 700019, India 2Department of Chemistry, National Research Institute of Ayurvedic Drug Development, Bidhannagar, Kolkata 700091, India&lt;/p&gt;</style></auth-address></record></records></xml>