<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Arifia Safira</style></author><author><style face="normal" font="default" size="100%">Prasita Widayani</style></author><author><style face="normal" font="default" size="100%">Dhiya An-Najaaty</style></author><author><style face="normal" font="default" size="100%">Cinta Atsa Mahesa Rani</style></author><author><style face="normal" font="default" size="100%">Mela Septiani</style></author><author><style face="normal" font="default" size="100%">Yan Arengga Syah Putra</style></author><author><style face="normal" font="default" size="100%">Tridiganita Intan Solikhah</style></author><author><style face="normal" font="default" size="100%">Aswin Rafif Khairullah</style></author><author><style face="normal" font="default" size="100%">Hartanto Mulyo Raharjo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Review of an Important Plants: Annona squamosa Leaf</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Annona squamosa</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicine</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacology</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemistry</style></keyword><keyword><style  face="normal" font="default" size="100%">Traditional medicinal plant</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">456-463</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Plants have been utilized extensively in traditional medicine by a range of nations since ancient times, and more research into their safety, efficacy, and quality value is needed. One of the plants that have been widely used by society in traditional medicine is Annona squamosa L. &lt;em&gt;A. squamosa &lt;/em&gt;is commonly cultivated in tropical and subtropical regions. Based on previous research, all parts of&lt;em&gt; A. squamosa&lt;/em&gt; including bark, leaf, and roots have proven biological activities such as antioxidant, antifungal, and anticancer, especially on the leaves. Indian people have long history used young leaves of &lt;em&gt;A. squamosa &lt;/em&gt;for antidiabetic, besides in South China, they use seeds to decrease the cancer effect in the human body. The pharmacological activities of &lt;em&gt;A. squamosa&lt;/em&gt; leaves are antimicrobial, antifungal, anti-inflammatory, anticancer, antiulcer, antidiabetic, antidiarrheals, antiplatelet, antioxidant, and hepatoprotective, neuroprotective, and cytoprotective. Phytochemicals in &lt;em&gt;A. squamosa&lt;/em&gt; leaves include coumarins, tannins, cardiac glycosides, flavonoids, carbohydrates, and saponins. Meanwhile based on nutritional analysis shows that the &lt;em&gt;A. squamosa &lt;/em&gt;leaves are water, protein, lipids, Fiber Ash and Calcium.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">456</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Arifia Safira&lt;sup&gt;1&lt;/sup&gt;, Prasita Widayani&lt;sup&gt;1&lt;/sup&gt;, Dhiya An-Najaaty&lt;sup&gt;1&lt;/sup&gt;, Cinta Atsa Mahesa Rani&lt;sup&gt;1&lt;/sup&gt;, Mela Septiani&lt;sup&gt;1&lt;/sup&gt;, Yan Arengga Syah Putra&lt;sup&gt;1&lt;/sup&gt;, Tridiganita Intan Solikhah&lt;sup&gt;1,*&lt;/sup&gt;, Aswin Rafif Khairullah&lt;sup&gt;2&lt;/sup&gt;, Hartanto Mulyo Raharjo&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Division of Veterinary Clinic, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Doctoral Program in Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Center of Excellence Fish Infectious Disease, Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, THAILAND.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mustanir</style></author><author><style face="normal" font="default" size="100%">Nurdin</style></author><author><style face="normal" font="default" size="100%">Binawati Ginting</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antioxidant Activity and Phytochemical Identification of Annona Squamosa Leaves Methanolic Extracts</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Annona squamosa</style></keyword><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">GC-MS.</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant extract</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1746-1750</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The antioxidant activity of &lt;em&gt;Annona squamosa &lt;/em&gt;(&lt;em&gt;A. squamosa&lt;/em&gt;) leaf was carried out using methanol extract and fractionated extract namely n-hexane, ethyl acetate and residue. The antioxidant activity of methanol extract and fractionated was performed using the 1-diphenyl-2-Pycrilhydrazil (DPPH) method. The antioxidant activity test of methanol extract and fractionated n-hexane, ethyl acetate and residue yielded IC&lt;sub&gt;50&lt;/sub&gt; of 6.87, 169.99, 31.55 and 44.75 ppm. The ethyl acetate fraction extract with IC&lt;sub&gt;50 &lt;/sub&gt;31.55 ppm was performed by column chromatography using silica gel G60 as the stationary phase and n-hexane: ethyl acetate as the mobile phase. The results of column chromatography obtained 181 fractions and were combined based on the stain pattern into 4 subfractions. Antioxidant test of each subfraction showed that the ASE 3 subfraction had the strongest antioxidant activity. Furthermore, the subfraction was analyzed using Gas Chromatography Mass Spectrometry (GC-MS). According, GC-MS data analysis showed that the third subfraction contained 19 phytochemical compounds, where 3 compounds having the highest concentration, namely 4,4'-((p-Phenylene)diisopropylidene) diphenol, dodecanoic acid, methyl ester and phthalic acid, isobutyl 2-methylpent-3-yl ester.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1746</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Mustanir&lt;sup&gt;1,&lt;/sup&gt;*, Nurdin&lt;sup&gt;1&lt;/sup&gt;, Binawati Ginting&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Arif Nur Muhammad Ansori</style></author><author><style face="normal" font="default" size="100%">Amaq Fadholly</style></author><author><style face="normal" font="default" size="100%">Annise Proboningrat</style></author><author><style face="normal" font="default" size="100%">Yulanda Antonius</style></author><author><style face="normal" font="default" size="100%">Suhailah Hayaza</style></author><author><style face="normal" font="default" size="100%">Raden Joko Kuncoroningrat Susilo</style></author><author><style face="normal" font="default" size="100%">Bilqis Inayatillah</style></author><author><style face="normal" font="default" size="100%">Mada Triandala Sibero</style></author><author><style face="normal" font="default" size="100%">Sin War Naw</style></author><author><style face="normal" font="default" size="100%">Gabrielle Ann Villar Posa</style></author><author><style face="normal" font="default" size="100%">Teguh Hari Sucipto</style></author><author><style face="normal" font="default" size="100%">Soegen Soegijanto</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Novel Antiviral Investigation of Annona squamosa Leaf Extract against the Dengue Virus Type-2: In vitro Study</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Annona squamosa</style></keyword><keyword><style  face="normal" font="default" size="100%">Antiviral activity</style></keyword><keyword><style  face="normal" font="default" size="100%">DENV-2</style></keyword><keyword><style  face="normal" font="default" size="100%">Vero cells</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">456-462</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Dengue virus (DENV) infection is general mosquito-transmitted viral taint. It can lead to the dengue hemorrhagic fever (DHF) or dengue shock syndrome (DSS). Dengue is a solemn illness with no endowed antiviral medication or recognized vaccine. Therefore, we aimed to investigate the activity of &lt;em&gt;Annona squamosa&lt;/em&gt; leaf extract (ASLE) against dengue virus type-2 (DENV-2) isolated from Surabaya, Indonesia in 2013 (NCBI accession number: KT012509). &lt;strong&gt;Methods: &lt;/strong&gt;In this study, the antiviral activity of ASLE was evaluated against DENV- 2 in Vero cells using Viral ToxGlo™ Assay. In addition, we used CellTiter-Glo&lt;sup&gt;®&lt;/sup&gt; Luminescent Cell Viability Assay to set the amount of viable cells in culture based on quantitation of the ATP. &lt;strong&gt;Results: &lt;/strong&gt;DENV-2 replication inhibited by ASLE in Vero cells with IC&lt;sub&gt;50&lt;/sub&gt; = 73.78 μg/mL and SI = 4.49 when cells were treated two days after virus infection, whereas its CC&lt;sub&gt;50&lt;/sub&gt; for cytotoxicity to Vero cells was 331.54 μg/mL. Interestingly, this is the first report on the investigation of ASLE against DENV-2. &lt;strong&gt;Conclusion:&lt;/strong&gt; In summary, ASLE demonstrated the antiviral activity against DENV-2 with less toxicity, and high possibility as a drug candidate. Therefore, it might be suggested for&lt;em&gt; in vivo&lt;/em&gt; assessment in the progress of a potent antiviral against DENV-2.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">456</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Arif Nur Muhammad Ansori&lt;sup&gt;1&lt;/sup&gt;, Amaq Fadholly&lt;sup&gt;1&lt;/sup&gt;, Annise Proboningrat&lt;sup&gt;1&lt;/sup&gt;, Yulanda Antonius&lt;sup&gt;2,&lt;/sup&gt;*, Suhailah Hayaza&lt;sup&gt;3&lt;/sup&gt;, Raden Joko Kuncoroningrat Susilo&lt;sup&gt;3&lt;/sup&gt;, Bilqis Inayatillah&lt;sup&gt;4&lt;/sup&gt;, Mada Triandala Sibero&lt;sup&gt;5&lt;/sup&gt;, Sin War Naw&lt;sup&gt;6&lt;/sup&gt;, Gabrielle Ann Villar Posa&lt;sup&gt;7&lt;/sup&gt;, Teguh Hari Sucipto&lt;sup&gt;8,&lt;/sup&gt;*, Soegeng Soegijanto&lt;sup&gt;8&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Doctoral Program in Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Biotechnology, University of Surabaya, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Doctoral Program in Mathematics and Natural Sciences, Faculty of Science and Technology, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Master Program in Basic Medical Science, Faculty of Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Marine Science, Faculty of Fisheries and Marine Science, Universitas Diponegoro, Semarang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Chemistry, Myitkyina University, Myitkyina, MYANMAR.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;School of Environmental Science and Management, University of the Philippines Los Baños, Los Baños, PHILIPPINES.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;8&lt;/sup&gt;Dengue Study Group, Institute of Tropical Disease, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mrinmoy Nag</style></author><author><style face="normal" font="default" size="100%">Pulok k Mukherjee</style></author><author><style face="normal" font="default" size="100%">Rajarshi Biswas</style></author><author><style face="normal" font="default" size="100%">Joydeb Chanda</style></author><author><style face="normal" font="default" size="100%">Amit Kar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation of Antimicrobial Potential of Some Indian Ayurvedic Medicinal Plants</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ananas comosus Merrill</style></keyword><keyword><style  face="normal" font="default" size="100%">Annona squamosa</style></keyword><keyword><style  face="normal" font="default" size="100%">Antibacterial</style></keyword><keyword><style  face="normal" font="default" size="100%">Capsicum annuum cayenne</style></keyword><keyword><style  face="normal" font="default" size="100%">Stereospermum suaveolens Roxb</style></keyword><keyword><style  face="normal" font="default" size="100%">Viscum articulatum Burm.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">525-533</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Stereospermum suaveolens&lt;/em&gt; Roxb., &lt;em&gt;Viscum articulatum&lt;/em&gt; Burm., &lt;em&gt;Annona squamosa, Capsicum annuum&lt;/em&gt; cayenne, &lt;em&gt;Ananas comosus&lt;/em&gt; Merrill. are used for the management of microbial infection in Ayurveda. The present study was designed to standardize the extract of &lt;em&gt;S. suaveolens&lt;/em&gt; bark (SSB), &lt;em&gt;V. articulatum&lt;/em&gt; aerial part (VAAP), &lt;em&gt;A. squamosa&lt;/em&gt; leaf (ASL), &lt;em&gt;C. annuum&lt;/em&gt; fruit (CACF), &lt;em&gt;A. comosus&lt;/em&gt; fruit (ACF) and performed antibacterial activity. &lt;strong&gt;Methods: &lt;/strong&gt;The antibacterial activity of the five extracts were evaluated against certain bacteria such as &lt;em&gt;B. subtilis, B. cereus, S. aureus &lt;/em&gt;(gram positive); &lt;em&gt;E. coli, S. typhi,&lt;/em&gt; and &lt;em&gt;P. aureugenosa&lt;/em&gt; (gram negative) by disc diffusion method, time course assay, pH sensitivity assay and minimum inhibitory concentration (MICs) through broth micro-dilution method. &lt;strong&gt;Results: &lt;/strong&gt;The plants extracts VAAP, ASL, and CACF showed potent inhibitory activity against &lt;em&gt;S. aureus&lt;/em&gt; with MIC 728, 742, and 698 &lt;em&gt;&amp;mu;&lt;/em&gt;g ml&lt;sup&gt;-1&lt;/sup&gt;, respectively, while CACF showed inhibitory activity against &lt;em&gt;B. subtilis&lt;/em&gt; with MIC 690 &lt;em&gt;&amp;mu;&lt;/em&gt;g ml&lt;sup&gt;-1&lt;/sup&gt;. The results further demonstrated that the inhibitory activity of CACF against &lt;em&gt;E. coli &lt;/em&gt;with MIC 760 &lt;em&gt;&amp;mu;&lt;/em&gt;g ml&lt;sup&gt;-1&lt;/sup&gt;. &lt;em&gt;P. aeruginosa&lt;/em&gt; was inhibited by ASL and CACF with MIC 1100 and 1120 &lt;em&gt;&amp;mu;&lt;/em&gt;g ml&lt;sup&gt;-1&lt;/sup&gt;, respectively. The ASL showed notable MBC against the tested microorganism. Moreover, all extracts were completely inactivated bacterial strains (except &lt;em&gt;B. cereus, S. typhi&lt;/em&gt;) within 2-10 h of exposure, determined by time course assay. &lt;strong&gt;Conclusion: &lt;/strong&gt;The outcomes of our study elucidate that standardized extracts of &lt;em&gt;A. comosus, A. squamosa, C. annuum, S. suaveolens, &lt;/em&gt;and&lt;em&gt; V. articulatum&lt;/em&gt; may be used as natural antimicrobial agents.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">525</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Mrinmoy Nag, Pulok k Mukherjee *, Rajarshi Biswas, Joydeb Chanda, Amit Kar &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmaceutical Technology, Jadavpur University, Kolkata-700032, INDIA.&lt;/p&gt;
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