<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Poulomi Chatterjee</style></author><author><style face="normal" font="default" size="100%">Abhay Nirgude</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Designing, Developing and Deploying Smart Nutrition Education Intervention to Promote Nutrition Related Knowledge among School Children: A Cluster Randomized Control Trial</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Child</style></keyword><keyword><style  face="normal" font="default" size="100%">Health-Education</style></keyword><keyword><style  face="normal" font="default" size="100%">Internet-Based Intervention</style></keyword><keyword><style  face="normal" font="default" size="100%">knowledge</style></keyword><keyword><style  face="normal" font="default" size="100%">Nutritional-Sciences</style></keyword><keyword><style  face="normal" font="default" size="100%">Schools</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">703-713</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;School-children undergo rapid growth with high nutritional needs. Adequate nutritionalknowledge promotes healthy eating making nutrition-education essential. This study assessed the impact of a digital platform-based smart nutrition-education intervention on nutritional-knowledge among 10-14-year-old school-children in Mangalore. &lt;strong&gt;Methods: &lt;/strong&gt;The study was conducted in five private schools with 596 children equally assigned to intervention and control-clusters (n=298 each). An orientation preceded baseline assessment. Intervention-cluster received a six-month digital program with two educational videos per month on nutrition, diet-planning, physical-activity, lifestyle, and personal-hygiene. Data were collected at baseline, post-intervention and six-month follow-up; control-cluster were assessed at baseline and follow-up. Within-group differences were analyzed using Friedman/Wilcoxon (Bonferroni) test, between-group Mann-Whitney U test with effect sizes Kendall’s W and r. Analyses were performed in SPSS 27 (p&amp;lt;0.05). &lt;strong&gt;Results:&lt;/strong&gt; At baseline, median nutritional-knowledge scores across all topics were similar between intervention and control-clusters with negligible effect-sizes (r) 0.001-0.024 and p&amp;gt;0.05. The intervention-cluster showed significant improvements across pre-test, post-test and follow-up (p&amp;lt;0.001) with pre-test to post-test (r=0.86-0.89) and pre-test to follow-up (r=0.84-0.89); a small decline from post-test to follow-up (r=0.20-0.62). The control-cluster showed no significant change (r=0.03-0.08, p&amp;gt;0.05). At follow-up intervention-cluster scored higher than controls across most topics (r=0.05-0.35, p&amp;lt;0.05) except “The food group system and its importance” (r=0.051, p=0.210). &lt;strong&gt;Conclusions:&lt;/strong&gt; The digital platform-based intervention significantly improved and sustained nutritional-knowledge among school-children. Its cost-effective, accessible and user-friendly design enables integration into educational systems, adaptation to other health programs and may support therapeutic dietary strategies. Future research should assess its translation into behavioural and health outcomes.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">703</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Poulomi Chatterjee&lt;sup&gt;1&lt;/sup&gt;, Abhay Nirgude&lt;sup&gt;1*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Community Medicine, Yenepoya Medical College (YMC), Yenepoya (Deemed to be University), Deralakatte, Mangalore 575018, Karnataka, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Pravanjan Kumar Tripathy</style></author><author><style face="normal" font="default" size="100%">Manas Ranjan Mishra</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Detail Study of an Ethnomedicinal Plant Sarcostemma Acidum Voigt</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ethnomedicinal uses</style></keyword><keyword><style  face="normal" font="default" size="100%">Macroscopy</style></keyword><keyword><style  face="normal" font="default" size="100%">microscopy</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacological Effects</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemicals</style></keyword><keyword><style  face="normal" font="default" size="100%">Sarcostemma acidum Voigt</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">188-190</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;em&gt;Sarcostemma acidum&lt;/em&gt; Voigt is a leafless plant of the family Apocynaceae. Plant is locally known as Somlata. It is a traditional medicinal plant used to prepare Somras. Geographically &lt;em&gt;S.acidum&lt;/em&gt; is mainly found in Bihar, West Bengal, Odisha and South India. It is mostly grown in dry rocky places. &lt;em&gt;S.acidum&lt;/em&gt; is a shrub , more branched but no leaves. The phytochemicals present in the &lt;em&gt;S.acidum&lt;/em&gt; are carbohydrates, glycosides, alkaloids, tannins, flavonoids, proteins, steroids, triterpenoids, fixed oils, mucilage, gums and waxes. Ethnomedicinally the&lt;em&gt; S.acidum&lt;/em&gt; was used in otitis, dog bite, snake bite, rabies, emesis, arthritis and leprosy. The juice of this plant having some medicinal value, so used as natural restorative for health. S.acidum stem extract inhibits spermatogenesis and reduce the sperm count. Also the extract of&lt;em&gt; S.acidum&lt;/em&gt; shown antipsychotic effect. The result of present pharmacological study shown that the &lt;em&gt;S.acidum&lt;/em&gt; possess Analgesic, Antipyretic and Antidiabetic effects.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">188</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Pravanjan Kumar Tripathy&lt;sup&gt;1&lt;/sup&gt;, Manas Ranjan Mishra&lt;sup&gt;2&lt;/sup&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Research Scholar, Biju Patnaik University of Technology, Rourkela, Odisha, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Professor &amp;amp; HOD, Dept. of Pharmacognosy, Gayatri College of Pharmacy, Odisha, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Omar Naseem Alzrigat</style></author><author><style face="normal" font="default" size="100%">Yazeed Nabeel Al-Qusous</style></author><author><style face="normal" font="default" size="100%">Dema Maher Masadeh</style></author><author><style face="normal" font="default" size="100%">Madleen Nabeel Al-Qusous</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Discover How Ashwagandha May Impact Health: A Comprehensive Review</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory</style></keyword><keyword><style  face="normal" font="default" size="100%">Anticancer dosage</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Ashwagandha</style></keyword><keyword><style  face="normal" font="default" size="100%">Toxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Withania somnifera</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">394-398</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Withania somnifera (Ashwagandha) is a medicinal herb that has been commonly utilized in traditional medicine for millennia, particularly in Ayurvedic practices. The root of the plant is pharmacologically active and has been used for its aphrodisiac, diuretic, anti-helminthic, narcotic, tonic, and stimulant properties. Additionally, other parts of ashwagandha, including the leaves, shoots, seeds, and berries, contribute to its health-promoting effects and the potential for improving longevity. This plant is composed of many bioactive compounds which exhibit a myriad of health-enhancing properties. Contemporary research has focused on the multifaceted bioactivities of ashwagandha, revealing promising impacts such as anticancer, antioxidant, and anti-inflammatory activities, among other therapeutic applications. This review was planned to find the most recent findings, providing an examination of the active constituents of ashwagandha, their biological activities, and a critical assessment of any associated safety concerns and potential toxicity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">394</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Omar Naseem Alzrigat&lt;sup&gt;1&lt;/sup&gt;, Yazeed Nabeel Al-Qusous&lt;sup&gt;2&lt;/sup&gt;, Dema Maher Masadeh&lt;sup&gt;1&lt;/sup&gt;, Madleen Nabeel Al- Qusous&lt;sup&gt;3*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;King Hussein Medical Center, Amman 11855, JORDAN.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Medicine, Mutah University, Al-Karak 61710, JORDAN.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Clinical Pharmacy, Faculty of Pharmacy, Mutah University, Al-Karak 61710, JORDAN.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Magdalena Paunno</style></author><author><style face="normal" font="default" size="100%">Ridwan Amiruddin</style></author><author><style face="normal" font="default" size="100%">Masni</style></author><author><style face="normal" font="default" size="100%">Mardiana Ahmad</style></author><author><style face="normal" font="default" size="100%">Bertha Jean Que</style></author><author><style face="normal" font="default" size="100%">Ridwan Thaha</style></author><author><style face="normal" font="default" size="100%">Sudirman Nasir</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determinants of Adverse Birth Outcomes in Ambon, Indonesia: A Case-Control Study</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">410-414</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Globally, adverse birth outcomes were still high, especially in low and middle-income countries like Indonesia. Stillbirth, preterm birth (PTB), low birth weight (LBW), and first-minute birth asphyxia are some of the adverse birth outcomes. The incidence of adverse birth in Ambon is quite high but never been any research about determinants of adverse birth outcomes. &lt;strong&gt;Objective:&lt;/strong&gt; This study aims to examine the determinants of adverse birth outcomes and identify the main modifiable risk factors in Ambon. Method: This retrospective case-control study included all birth outcomes in August and September 2023 in Ambon, Indonesia. A total of 165 birth outcomes (55 cases and 110 controls) with complete information in Puskesmas and Posyandu were included in the analysis. The Chi-square test and regression analyses were applied to evaluate the association between variables. &lt;strong&gt;Result: &lt;/strong&gt;This study showed the impact of pregnant women's age, parity, passive smoking, ANC examination, and ANC counseling on birth outcomes. There are differences in maternal age (p=0.006; 95% CI: 1.22-6.11), parity (p=0.001; 95% CI: 1.52-8.51), passive smokers (p=0.004; 95% CI: 1.37-8.99, ANC examination (p=0.02; 95% CI: 1.08-5.01) and ANC counseling (p=0.002; 95% CI: 1.44-8.67) between case and control groups. &lt;strong&gt;Conclusion: &lt;/strong&gt;Maternal age (≤ 20 and &amp;gt;35 years old), parity (one and ≥ 5), passive smokers, ANC examination not according to standard, and ANC counseling without a husband were associated with a high risk of all adverse birth outcomes.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">410</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Magdalena Paunno&lt;sup&gt;1,*&lt;/sup&gt;, Ridwan Amiruddin&lt;sup&gt;2&lt;/sup&gt;, Masni&lt;sup&gt;3&lt;/sup&gt;, Mardiana Ahmad&lt;sup&gt;4&lt;/sup&gt;, Bertha Jean Que&lt;sup&gt;5&lt;/sup&gt;, Ridwan Thaha&lt;sup&gt;6&lt;/sup&gt;, Sudirman Nasir&lt;sup&gt;6&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;7&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Doctor of Public Health Sciences, Faculty of Public Health, Universitas Hasanuddin, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Epidemiology, Faculty of Public Health, Universitas Hasanuddin, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Department Reproductive Health and Family, Faculty of Public Health, Universitas Hasanuddin, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Midwifery, Faculty of Public Health, Universitas Hasanuddin, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;5&lt;/sup&gt;Medical Faculty, Universitas Pattimura, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;6&lt;/sup&gt;Faculty of Public Health, Universitas Hasanuddin, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;7&lt;/sup&gt;Department of Environmental Health, Faculty of Public Health, Universitas Hasanuddin, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hilda Harun</style></author><author><style face="normal" font="default" size="100%">Ridwan Amiruddin</style></author><author><style face="normal" font="default" size="100%">A. Arsunan Arsin</style></author><author><style face="normal" font="default" size="100%">Abdul Salam</style></author><author><style face="normal" font="default" size="100%">Mondastri Korib Sudaryo</style></author><author><style face="normal" font="default" size="100%">H. Muh. Syafar</style></author><author><style face="normal" font="default" size="100%">A. Ummu Salmah</style></author><author><style face="normal" font="default" size="100%">Sudirman Natsir</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development and Feasibility Test of the Self-Management Hypertension (SMH) Application for Elderly People with Hypertension in Makassar City</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Elderly</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypertension</style></keyword><keyword><style  face="normal" font="default" size="100%">Self Management</style></keyword><keyword><style  face="normal" font="default" size="100%">SMH Application</style></keyword><keyword><style  face="normal" font="default" size="100%">TAM.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">902-909</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;The Self &lt;em&gt;Management Hypertension &lt;/em&gt;(SMH) application is a digital-based educational media solution to improve knowledge of elderly with HT in managing their disease independently, easy to use and can be accessed wherever they are. &lt;em&gt;Smartphone&lt;/em&gt; -based digital technology, Recently, it has become a very common tool needed by most people, including the elderly, not only as a communication tool but can also be used as a medium for education and information. Research &lt;strong&gt;Objectives:&lt;/strong&gt; This research aims to design the development of a prototype of the SMH application and to determine the feasibility of the SMH application for self-management of hypertension for the elderly. &lt;strong&gt;Method:&lt;/strong&gt; The research method used is &lt;em&gt;Research and Development &lt;/em&gt;(R&amp;amp;D). The research subjects for the expert validation test consisted of 3 experts. Meanwhile, the application trial subjects consisted of a one-on-one trial sample of 3 elderly people and a small group trial of 12 elderly people. Data collection uses the &lt;em&gt;Technology Acceptance&lt;/em&gt; Model (TAM) questionnaire which consists of 13 questions with 4 assessment aspects, namely the convenience aspect, usefulness aspect, trust aspect and user intention aspect. There are 4 Likert scale answer choices ranging from strongly agree to strongly disagree. &lt;strong&gt;Results:&lt;/strong&gt; Expert validation results show the percentage and eligibility criteria are 86.6%. The results of one-on-one trials show that the ease of application aspect is in the range of 3.25-4.00, the usefulness aspect is in the range of 3.00-4.00, the trust aspect is in the range of 3.67-4.00 and the user intention aspect is in the range of 3.00-4. .00. Small group trials showed an average convenience aspect of 3.52, an average usefulness aspect of 3.53, an average trust aspect of 3.69 and an average user intention aspect of 3.64. &lt;strong&gt;Conclusion&lt;/strong&gt;: The SMH application has decent content, is easy to use, very useful, and trustworthy, thereby increasing the intention of elderly people with HT to use the SMH application&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">902</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Hilda Harun&lt;sup&gt;1*&lt;/sup&gt;, Ridwan Amiruddin&lt;sup&gt;2&lt;/sup&gt;, A. Arsunan Arsin&lt;sup&gt;2&lt;/sup&gt;, Abdul Salam&lt;sup&gt;3&lt;/sup&gt;, Mondastri Korib Sudaryo&lt;sup&gt;4&lt;/sup&gt;, H. Muh. Syafar&lt;sup&gt;5&lt;/sup&gt;, A. Ummu Salmah&lt;sup&gt;6&lt;/sup&gt;, Sudirman Natsir5, Anwar Mallongi&lt;sup&gt;7&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Doctoral Student in Public Health Sciences, Public Health Sciences Study Program, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Promoter and Co Promoter, Professor Department of Epidemiology, Faculty of Public Health,&amp;nbsp;Hasanuddin University, Makassar INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Doctoral Department of Nutrition, Faculty of Public Health,&amp;nbsp;Hasanuddin University, Makassar INDONESIA. 4Professor, Department of Epidemiology, Faculty of Public Health, University of Indonesia, Jakarta INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Professor, Department of Health Promotion and Behavioral Sciences, Faculty of Public Health,&amp;nbsp;Hasanuddin University, Makassar INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Professors at the Department of&amp;nbsp;Biostatistics, Faculty of Public Health, Hasanuddin University, Makassar Indonesia&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Professor, Department of Environmental Health, Faculty of Public Health,&amp;nbsp;Hasanuddin University, Makassar INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Suparmi</style></author><author><style face="normal" font="default" size="100%">Sumarto</style></author><author><style face="normal" font="default" size="100%">Hendro Ekwarso</style></author><author><style face="normal" font="default" size="100%">Isna Rahma Dini</style></author><author><style face="normal" font="default" size="100%">Ranika Paramita</style></author><author><style face="normal" font="default" size="100%">Syafrani</style></author><author><style face="normal" font="default" size="100%">Taufik Hidayat</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Diversification, Organoleptic and Chemical Quality Characteristics of Processed Products Based on Thorn Fish (Hexanematichthys sagor) Smoke</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Diversification</style></keyword><keyword><style  face="normal" font="default" size="100%">Ecowisata</style></keyword><keyword><style  face="normal" font="default" size="100%">Healthy</style></keyword><keyword><style  face="normal" font="default" size="100%">Nutrition</style></keyword><keyword><style  face="normal" font="default" size="100%">Profile</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">606-609</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The potential of Rupat Island's marine natural resources can be seen from the diversity of its marine and mangrove ecosystems. This coastal area has natural resource potential, both marine products and no less important is its marine ecotourism area. The marine tourism area is found at Pesona Beach, Lampin Beach, Ketapang Beach, Makeruh Beach, and Putri Sembilan Beach which have an important role in increasing regional income. The aim of the research is to increase the potential of processed fishery products as souvenirs and tourism. The research method is an experiment using a completely randomized design, with treatments MS0 (smoked fish control), MS1 (smoked fish rendang) and MS2 (smoked fish rendang) and MS3 (Flossed fish). smoke) repeated 3 times. The parameters analyzed are organoleptic (appearance, texture, aroma, taste). The results of the research showed that the best treatment was MS2 (Smoked fish sorondeng) which was liked by the panelists which had the characteristics of a bright yellow color, the aroma of burnt coconut, the texture of mersik was not hard and crunchy, and the taste was savory, with a taste score of 8.6, aroma 8.4 , appearance 8.8, texture 8.5. This product has the characteristics of a bright brownish yellow color, a non-fishy aroma, a smooth texture and a very savory taste (umami). From the results of the threshold test on functional flavor powder, the threshold value was obtained, namely at a concentration of 9% with a taste value of 8.6, aroma 8. .4, appearance 8.8, texture 8.5. This product has the characteristics of a bright yellowish white color, a non-fishy aroma, a smooth texture and a very savory taste (umami)&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">606</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Suparmi&lt;sup&gt;1&lt;/sup&gt;*, Sumarto&lt;sup&gt;1&lt;/sup&gt;, Hendro Ekwarso&lt;sup&gt;2&lt;/sup&gt;, Isna Rahma Dini&lt;sup&gt;3&lt;/sup&gt;, Ranika Paramita&lt;sup&gt;3&lt;/sup&gt;, Syafrani&lt;sup&gt;4&lt;/sup&gt;, Taufik Hidayat&lt;sup&gt;5&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Fisheries Product Technology, Riau University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Departement of Economics, Development Economics, Riau University.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Univeristy of Hang Tuah, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Agrotechnology Study Program, Faculty of Agriculture, Universty of Lancang Kuning, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Research Center for Agroindustry, National Innovation Research Agency, Laptiab Building 614, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Prasad Thakurdesai</style></author><author><style face="normal" font="default" size="100%">Pallavi Deshpande</style></author><author><style face="normal" font="default" size="100%">Namrata Desai</style></author><author><style face="normal" font="default" size="100%">Prasanna Mathad</style></author><author><style face="normal" font="default" size="100%">Sandhya Rani</style></author><author><style face="normal" font="default" size="100%">Dhananjay Raje</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A Double-blind, Randomized Controlled Study of Triterpenoids based Standardized Gotu Kola Leaves Extract in the Patients with Tension Type Headache</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Centella asiatica leaves; Chronic Stress; Pain; Work productivity</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">1238-1251</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Triterpenoid-based standardized &lt;em&gt;Centella asiatica&lt;/em&gt; leaves extract as nasal solution (INDCANS) has shown potential in animal models of stress-related disorders. &lt;strong&gt;Objective:&lt;/strong&gt; Efficacy and safety evaluation of INDCA-NS in patients with Tension-type headache (TTH). &lt;strong&gt;Methods: &lt;/strong&gt;Ninety-one patients with TTH were randomized and administered INDCA-NS (46 patients) or PLACEBOCA-NS (45 patients) nasal spray (400 μg/day, 100 μg in 100 μL shot/ nostril, twice daily) for 28 days, with a 14-day follow-up. Efficacy (headache duration, frequency, and intensity; 21-item “Depression, Anxiety, and Stress Scale” (DASS-21); “Work Productivity and Activity Questionnaire” (WPAI: SHP); “World Health Organization Brief” (WHOQOL-BREF), cortisol and DHEA levels, rescue medications), and safety outcome measures (including adverse events) were monitored.&lt;strong&gt; Results: &lt;/strong&gt;Subacute administration of INDCA-NS (but not PLACEBOCA-NS) significantly reduced the duration of headache and TTH's effect of TTH on WPAI:SHP (Q5) scores, namely productivity in working patients (P &amp;lt; 0.05, within the groups). The INDCA-NS showed significant difference (P &amp;lt; 0.05) in headache duration with and without covariate adjustment (vs. PLACEBOCA-NS). Both treatments found safe, well- tolerated, with no treatment-related adverse events, significantly reduced headache frequency, pain intensity, DASS-21 (stress domain), TTH's impact on daily activities (Q6 of WPAI:SHP), and improved WHOQOL scores (P &amp;lt; 0.05, within the group). The other outcome measures were not statistically significant within or between groups. &lt;strong&gt;Conclusion: &lt;/strong&gt;Subacute INDCA-NS reduced headache duration and improved work productivity in TTH patients.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1238</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Prasad Thakurdesai*, Pallavi Deshpande, Namrata Desai, Prasanna Mathad , Sandhya Rani, Dhananjay Raje&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Pharmacology, Poona College of Pharmacy, Bharati Vidyapeeth Deemed University, Pune, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yunita Cahyani Pratiwi</style></author><author><style face="normal" font="default" size="100%">Darmawansyah</style></author><author><style face="normal" font="default" size="100%">Sukri Palutturi</style></author><author><style face="normal" font="default" size="100%">Amran Razak</style></author><author><style face="normal" font="default" size="100%">Atjo Wahyu</style></author><author><style face="normal" font="default" size="100%">Anwar Daud</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Drug Management and Service Quality in Outpatient Pharmacies at the Haji Padjonga Daeng Ngalle Regional General Public Hospital in Takalar Regency, Indonesia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Drug management</style></keyword><keyword><style  face="normal" font="default" size="100%">Hospital</style></keyword><keyword><style  face="normal" font="default" size="100%">outpatient unit.</style></keyword><keyword><style  face="normal" font="default" size="100%">patient service quality</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">838-844</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; The provision of comprehensive individual health care services in outpatient units is intricately linked to drug management practices and the quality of available pharmacy services, ensuring optimal medication supply and use.&lt;strong&gt; Objective: &lt;/strong&gt;This study aimed to assess the practices of drug management and the quality of outpatient pharmacy services at Haji Padjonga Daeng Ngalle (HPDN) Regional General Public Hospital in Takalar Regency, Indonesia. &lt;strong&gt;Method:&lt;/strong&gt; The evaluation of drug management involves conducting in-depth interviews in the outpatient unit, focusing on planning, budgeting, procurement, storage, and distribution, compared with government regulatory standards. The quality of pharmacy services was assessed using the Solvin technique with 100 respondents, evaluating five dimensions: physical evidence, reliability, responsiveness, assurance, and empathy, using the servqual questionnaire with a Likert scale (ranging from very dissatisfied = 1, dissatisfied = 2, somewhat satisfied = 3, satisfied = 4, to very satisfied = 5). &lt;strong&gt;Results:&lt;/strong&gt; Research findings indicated the level of compliance of drug management with regulations as follows: planning (66.67%), budgeting (60%), procurement (100%), storage (100%), and distribution (100%). The quality of pharmacy services demonstrated high questionnaire validity (r ≥ 0.714), and the average dimension was a score of 4, indicating satisfactory satisfaction levels. Conclusion: This study reflects HPDN hospital’s compliance with regulations while identifying specific areas for improvement to enhance the quality of pharmacy services.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">838</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Yunita Cahyani Pratiwi&lt;sup&gt;1,*&lt;/sup&gt;, Darmawansyah&lt;sup&gt;2&lt;/sup&gt;, Sukri Palutturi&lt;sup&gt;2&lt;/sup&gt;, Amran Razak&lt;sup&gt;2&lt;/sup&gt;, Atjo Wahyu&lt;sup&gt;3&lt;/sup&gt;, Anwar Daud&lt;sup&gt;4&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;4&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Master’s Program, Department of Health Policy Administration, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Health Policy Administration, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Occupational Health and Safety, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Environmental Health, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Raden Muharam</style></author><author><style face="normal" font="default" size="100%">Nurhuda Sahar</style></author><author><style face="normal" font="default" size="100%">Kusmardi Kusmardi</style></author><author><style face="normal" font="default" size="100%">Luluk Yunaini</style></author><author><style face="normal" font="default" size="100%">Risqa Novita</style></author><author><style face="normal" font="default" size="100%">Rosalina Thuffi</style></author><author><style face="normal" font="default" size="100%">Conny Riana Tjampakasari</style></author><author><style face="normal" font="default" size="100%">Ponco Birowo</style></author><author><style face="normal" font="default" size="100%">Diyah Kristanty</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Decreased Expression of Endocrine Glands Vascular Endothelial Growth Factor (EG-VEGF) in Rat Endometrial After Stimulation with Recombinants FSH Can be Reduce Implantation Rates</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">EG-VEGF</style></keyword><keyword><style  face="normal" font="default" size="100%">Endometrial receptivity</style></keyword><keyword><style  face="normal" font="default" size="100%">rFSH</style></keyword><keyword><style  face="normal" font="default" size="100%">Secretory phase.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">707-713</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Decreased expression of EG-VEGF in human endometrium after administration of ovarian stimulators has been reported to adversely affect endometrial receptivity and low implantation rates. &lt;strong&gt;Objective:&lt;/strong&gt; To determine the effect of recombinant FSH administration on EG-VEGF protein in the endometrium of rats taken in the secretory phase and how it relates to endometrial receptivity. Design: A total of 36 female wistar rats with normal estrous cycles were randomly assigned to the natural cycle group (NC) and two stimulation groups (SC) which were injected with recombinant FSH at 12.5 IU and 25 IU intraperitoneally. Uterine necropsy and blood collection were performed on day 1, day 2, and day 3 after hCG administration. A total of 3 female rats from each group were mated with male rats (two males and three females in one cage). A successful marriage is indicated by the presence of a vaginal plug the next day. The level of EG-VEGF protein expression was assessed by immunohistochemical technique and steroid hormone levels were measured by the Elisa technique. &lt;strong&gt;Results&lt;/strong&gt;: ANOVA test, that the expression of EG-VEGF in the endometrial glands showed a significant decrease from the normal cycle group to the stimulated cycle group 1 (SC 1) and SC2 (P = 0.00), as well as the expression of EG-VEGF in the endometrial stroma. (P = 000). Steroid hormone levels did not show a significant decrease between the normal cycle group and the stimulated cycle group (P = 0.48 and P = 0.13). &lt;strong&gt;Conclusion:&lt;/strong&gt; Decreased EG-VEGF expression in rat endometrium after administration of recombinant FSH is associated with decreased endometrial receptivity which can reduce pregnancy rates.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">707</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Raden Muharam&lt;sup&gt;1&lt;/sup&gt;, Nurhuda Sahar&lt;sup&gt;2&lt;/sup&gt;, Kusmardi Kusmardi&lt;sup&gt;3,5,*&lt;/sup&gt;, Luluk Yunaini&lt;sup&gt;6&lt;/sup&gt;, Risqa Novita&lt;sup&gt;7&lt;/sup&gt;, Rosalina Thuffi&lt;sup&gt;8&lt;/sup&gt;, Conny Riana Tjampakasari&lt;sup&gt;9&lt;/sup&gt;, Ponco Birowo&lt;sup&gt;10&lt;/sup&gt;, Diyah Kristanty&lt;sup&gt;11&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Medical Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Drug Development Research Center, Indonesia Medical Education and Research Institute, Universitas Indonesia, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Human Cancer Research Center, Indonesia Medical Education and Research Institute, Universitas Indonesia, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Medical Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Center of Biomedical and Basic Health Technology, Ministry of Health of the Republic of Indonesia, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;8&lt;/sup&gt;Master Programe of Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;9&lt;/sup&gt;Department of Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;10&lt;/sup&gt;Department of Urology Faculty of Medicine, Universitas Indonesia, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;11&lt;/sup&gt;Department of Clinical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ruqiah Ganda Putri Panjaitan</style></author><author><style face="normal" font="default" size="100%">Titin</style></author><author><style face="normal" font="default" size="100%">Yohanes Gatot Sutapa Yuliana</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Description of Ciplukan Toxicity (Physalis angulata L.)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acute toxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Ciplukan</style></keyword><keyword><style  face="normal" font="default" size="100%">Condition</style></keyword><keyword><style  face="normal" font="default" size="100%">Dosage</style></keyword><keyword><style  face="normal" font="default" size="100%">Traditional medicine.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">357-367</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction&lt;/strong&gt;: Ciplukan (&lt;em&gt;Physalis angulata &lt;/em&gt;L.) is a plant used by Indonesian people as traditional medicine. Drug sanitization needs to be carried out to guarantee the use and availability of scientifically safe traditional medicines. This study aims to provide information and enrich knowledge about the safety of consuming ciplukan roots and stems. &lt;strong&gt;Methods:&lt;/strong&gt; This study used 8 male mice as test animals, divided randomly into 4 treatment groups, namely mice treated with a dose of 0.56 mg/20 g body weight; mice treated with a dose of 5.6 mg/20 g body weight; mice treated with 56 mg/20 g body weight; and mice treated with 560 mg/20 g body weight. Treatment was given once and then observed for 24 hours to observe the number of deaths of the test animals. Then follow-up observations were carried out in 3 days on individuals who were still alive. &lt;strong&gt;Results:&lt;/strong&gt; Within 24 hours all individuals at the treatment dose of 0.56 mg/20 g body weight survived, whereas all individuals at the treatment dose of 5.6; 56; and 560 mg/20 g body weight died. The observations on individuals treated at a dose of 0.56 mg/20 g body weight showed that the animals were in good condition, with sleeping and eating activities, moving a lot, having clean and nice fur, and not showing toxic symptoms such as disturbances in physical activity, impaired balance, and refusal to eat. &lt;strong&gt;Conclusions:&lt;/strong&gt; The administration of the test extract below is less or equal to 0.56 mg/20 g body weight is relatively safe.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">357</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ruqiah Ganda Putri Panjaitan&lt;sup&gt;1,*&lt;/sup&gt;, Titin&lt;sup&gt;1&lt;/sup&gt;, Yohanes Gatot Sutapa Yuliana&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biology Education, Faculty of Teacher Training and Education, Tanjungpura University. Jl. Prof. Dr. H. Hadari Nawawi, Bansir Laut, Kec. Pontianak Tenggara, Kota Pontianak, West Kalimantan 78124, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of English Education, Faculty of Teacher Training and Education, Tanjungpura University. Jl. Prof. Dr. H. Hadari Nawawi, Bansir Laut, Kec. Pontianak Tenggara, Kota Pontianak, West Kalimantan 78124, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Tarkeshwar Dubey</style></author><author><style face="normal" font="default" size="100%">Kancharla Bhanukiran</style></author><author><style face="normal" font="default" size="100%">Kuna Das</style></author><author><style face="normal" font="default" size="100%">Siva Hemalatha</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development and Evaluation of Bio fabricated Silver Nanoparticles from Blumea lacera for In-vitro Antibacterial, Antioxidant and Anti-inflammatory Activity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Green synthesis</style></keyword><keyword><style  face="normal" font="default" size="100%">HPTLC.</style></keyword><keyword><style  face="normal" font="default" size="100%">Inflammation</style></keyword><keyword><style  face="normal" font="default" size="100%">Kukrounda</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytopharmaceuticals</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">266-278</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Increasing prevalence of microbial resistance and side effects of currently available drugs compels the researchers to look for alternate therapies and formulations to overcome this problem. Plant based formulations have been proved to be most reliable agents in recent times. &lt;strong&gt;Objective: &lt;/strong&gt;In the current study, bio fabricated herbal silver nanoparticles (HSNPs) were prepared by reducing silver nitrate (AgNO&lt;sub&gt;3&lt;/sub&gt;) solution with ethyl acetate fractions (EAF) of &lt;em&gt;Blumea lacera &lt;/em&gt;extracts. These bios conjugated HSNPs were then assessed for potential anti-inflammatory and antibacterial activities along with&lt;em&gt; in vitro&lt;/em&gt; antioxidant effect. &lt;strong&gt;Methods and Results: &lt;/strong&gt;The synthesis was confirmed by absorbance peak at 441 nm due to surface plasmon resonance in UV-visible spectrophotometer. FTIR spectra of HSNPs indicated the phytochemicals having C-O bond responsible for reducing of Ag&lt;sup&gt;+&lt;/sup&gt; to Ag&lt;sup&gt;o&lt;/sup&gt;. Average size of HSNPs was found to be 59.21 nm which was in good agreement with TEM and SEM results. EDS analysis showed the existence of Silver, Nitrogen and Carbon in HSNPs. The antibacterial activity of HSNPs in terms of zone of inhibition (ZOI) &lt;em&gt;via&lt;/em&gt; disc diffusion assay and against &lt;em&gt;Staphylococcus aureus&lt;/em&gt; and &lt;em&gt;Escherichia coli &lt;/em&gt;was found to be 25.0±1.19 mm and 18.3±2.08 mm, respectively. The minimum inhibitory concentration (MIC) of HSNPs was found to be 50 μg/ml and 60 μg/ml against S. aureus and E. coli, respectively. The antioxidant capacity of the HSNPs was insignificant as compared to EAF but the results of anti-inflammatory activity was significant (p&amp;lt;0.05).&lt;strong&gt; Conclusion:&lt;/strong&gt; The overall result demonstrated better &lt;em&gt;in-vitro&lt;/em&gt; pharmacological potential of HSNPs compared to neat extract/EAF. Key words: Green synthesis, Phytopharmaceuticals, Inflammation, Kukrounda, HPTLC.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><section><style face="normal" font="default" size="100%">266</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Tarkeshwar Dubey&lt;sup&gt;1&lt;/sup&gt;, Kancharla Bhanukiran&lt;sup&gt;1&lt;/sup&gt;, Kuna Das&lt;sup&gt;2&lt;/sup&gt;, Siva Hemalatha&lt;sup&gt;1,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Engineering &amp;amp; Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi-221005, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Odisha-769008, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hilda</style></author><author><style face="normal" font="default" size="100%">Supriadi</style></author><author><style face="normal" font="default" size="100%">Hesti Prawita Widiastuty</style></author><author><style face="normal" font="default" size="100%">Arsyawina</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development of Patient Safety Management Learning Model Based on Problem Based Learning Integrated Soft Skill Higher Level Thinking for Health Students in Samarinda</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Patient Safety</style></keyword><keyword><style  face="normal" font="default" size="100%">Problem Based Learning</style></keyword><keyword><style  face="normal" font="default" size="100%">Soft skills.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">418-423</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Nursing students who participate in clinical practice in hospitals are not ready to provide quality care in maximizing patient safety. This study aims to develop a Problem Based Learning Patient Safety (PBLPS) conceptual model design that stimulates high-level thinking soft skills for students and finds PBLPS learning tools. &lt;strong&gt;Method:&lt;/strong&gt; Research and Development (R&amp;amp;D), which is a research method that aims to produce new products through a development process. The stages of the research method consist of 3 stages, namely: the preliminary study stage; model development stage; model testing stage. The research subjects were nursing students at tertiary institutions in Samarinda city who had taken patient safety management courses, totaling 162 people. Data were analyzed using the Wilcoxon test. &lt;strong&gt;Results&lt;/strong&gt;: Patient safety goals have not been implemented properly by students who practice clinical practice in hospitals. Students state that case-based learning can improve both hard skills and soft skills. The design of the integrated Problem Based Learning (PBL) learning model and the integrated PBLPS learning tools developed are RPS and integrated PBL-based modules on patient safety management. The results of the analysis of the soft skills assessment of high-level thinking students who practice in hospitals in the first year and the second-year show that there are differences in the results of the assessment of high-level thinking soft skills in the application of patient safety. &lt;strong&gt;Conclusion:&lt;/strong&gt; The Problem Based Learning Patient Safety (PBLPS) conceptual model can stimulate high-order thinking soft skills for students in patient safety management practices in hospitals.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">418</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Hilda&lt;sup&gt;1,*&lt;/sup&gt;, Supriadi&lt;sup&gt;1&lt;/sup&gt;, Hesti Prawita Widiastuty&lt;sup&gt;1&lt;/sup&gt;, Arsyawina&lt;sup&gt;1&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Nursing Department, Health Polytechnic, Ministry of Health, East Kalimantan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Environmental Health Department, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ruqiah Ganda Putri Panjaitan</style></author><author><style face="normal" font="default" size="100%">Afandi</style></author><author><style face="normal" font="default" size="100%">Syarifah Ditha Aprilia</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Diuretic Potency of Belalai Gajah Plants (Clinacanthus nutans (Burm.fil.) Lindau)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Clinacanthus nutans (Burm.fil.) Lindau</style></keyword><keyword><style  face="normal" font="default" size="100%">Diuretic Potency</style></keyword><keyword><style  face="normal" font="default" size="100%">Urine.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">365-369</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Backgrounds: &lt;/strong&gt;The use of&lt;em&gt; belalai gajah&lt;/em&gt; plants (&lt;em&gt;Clinacanthus nutans&lt;/em&gt; (Burm.fil.) Lindau) is believed by the Chinese community to be able to treat hypertension, so to prove whether this power exists in &lt;em&gt;belalai gajah&lt;/em&gt; plants is to do a diuretic activity test. &lt;strong&gt;Objective of Study:&lt;/strong&gt; to determine the presence of diuretic potency in &lt;em&gt;belalai gajah&lt;/em&gt; plants. &lt;strong&gt;Methods:&lt;/strong&gt; This test used male white rats of the Sprague Dawley strain with a body weight of 200-250 grams aged 2-2.5 months as many as 35 rats which were divided into 7 groups. The first group or no treatment, the second group with 2.8 ml/200 g body weight of distilled water, the third and fourth groups with 0.72 mg/200 g body weight of furosemide and 1.44 mg/200 g body weight, the fifth, sixth, and seventh groups with administration of &lt;em&gt;belalai gajah&lt;/em&gt; plants extract doses of 75 mg/kg body weight, 150 mg/kg body weight, and 300 mg/kg body weight. This test uses the Cumming method. Urine collection was carried out for 24 hours, then urine volume, urine pH, also sodium and potassium levels in rat urine were measured.&lt;strong&gt; Results:&lt;/strong&gt; The results of this study showed that without treatment, the administration of distilled water at a dose of 2.8 ml/200 g body weight, furosemide at a dose of 0.72 mg/200 g body weight and 1.44 mg/200 g body weight, and&lt;em&gt; belalai gajah&lt;/em&gt; plants extract at a dose of 75 mg/kg body weight, 150 mg/kg body weight, and 300 mg/kg body weight resulted in a urine volume of 13.01 ± 0.07 ml; 13.77±0.17 ml; 15.78± 0.39 ml; 18.13±0.23 ml; 14.05±0.06 ml; 16.78±0.12 ml; 17.98±0.09 ml (p&amp;lt;0.5). Furthermore, the urine pH was successively 7.02 ± 0.04; 7.11±0.02; 7.21±0.02; 7.58±0.18; 7.15±0.03; 7.37±0.03; 7.44±0.02 (p&amp;gt;0.5). The results of sodium levels in urine were respectively 1.06±0.03 mEq/ ml; 1.14±0.03 mEq/ml; 2.17±0.09 mEq/ml; 4.01±0.069 mEq/ml; 1.34±0.08 mEq/ml; 1.49±0.02mEq/ml; 1.77 ±0.05 mEq/ml (p&amp;lt;0.5) and urinary potassium levels 0.5±0.03 mEq/ml, respectively; 0.57±0.018 mEq/ ml; 0.98±0.023 mEq/ml; 1.88±0.04 mEq/ml; 0.6±0.02 mEq/ml; 0.76±0.021 mEq/ml; 0.87±0.032 mEq/ ml (p&amp;lt;0.5). &lt;strong&gt;Conclusion&lt;/strong&gt;: &lt;em&gt;Belalai gajah &lt;/em&gt;plants extract at a dose of 300 mg/kg body weight has the ability to increase urine volume which is close to the urine volume by administering furosemide 1.44 mg/200 g body weight. &lt;em&gt;Belalai gajah &lt;/em&gt;plants extract at a dose of 75 mg/kg body weight had a urine pH close to urine pH by administering distilled water at a dose of 2.8 ml/200 g body weight and 0.72 mg furosemide/200 g body weight. Giving &lt;em&gt;belalai gajah &lt;/em&gt;plants extract at a dose of 75 mg/kg body weight has potassium levels in the urine that are close to urine potassium levels by administering distilled water.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">365</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Ruqiah Ganda Putri Panjaitan*, Afandi, Syarifah Ditha Aprilia&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Biological Education, Faculty of Teacher Training and Education, Universitas Tanjungpura Pontianak, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Abdul Hapid</style></author><author><style face="normal" font="default" size="100%">Ariyanti Ariyanti</style></author><author><style face="normal" font="default" size="100%">Erniwati Erniwati</style></author><author><style face="normal" font="default" size="100%">Ni Made Dharma Shantini Suena</style></author><author><style face="normal" font="default" size="100%">Ketut Agus Adrianta</style></author><author><style face="normal" font="default" size="100%">Karnita Yuniarti</style></author><author><style face="normal" font="default" size="100%">Muthmainnah Muthmainnah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Diversity of Types of Medicinal Plants and Local Wisdom of the Kaili Tribe in Processing Medicinal Plants Around the Forest Areas of Central Sulawesi, Indonesia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Kaili tribe</style></keyword><keyword><style  face="normal" font="default" size="100%">Local knowledge</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Species diversity.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">535-540</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The forest area in Sigi Regency, Central Sulawesi, is a habitat for various medicinal plant species. Forest areas must be managed appropriately for the local community and society's welfare and sustainable use. One of the local people living around the forest is the Kaili tribe. The local wisdom of the Kaili tribe, who inhabit forest areas in Central Sulawesi, in managing forests and forest products, especially using plants as medicine, must be documented in research. This study aimed to identify the species, habitat, habitus, and ways of using the plant as medicine by the Kaili people in the Sigi Regency. Prior to data collection, a literature study was conducted to obtain information regarding the condition of the research location around the forest area and the ethnic/ethnic groups who live permanently around and within the forest area. This stage was then followed by interviews and field surveys. The interviews were conducted by combining purposive sampling and snowball methods. The results showed the high potency of medicinal plants around forest areas used by the Kaili tribe, with the discovery of 113 species in 51 families. Herbs are the most common habitus of medicinal plants. The habitat of medicinal plants is mainly found in the yard. The most used plant part is the leaves, which can be boiled in water and drunk directly.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><section><style face="normal" font="default" size="100%">535</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Abdul Hapid&lt;sup&gt;1,*&lt;/sup&gt;, Ariyanti Ariyanti&lt;sup&gt;1&lt;/sup&gt;, Erniwati Erniwati&lt;sup&gt;1&lt;/sup&gt;, Ni Made Dharma Shantini Suena&lt;sup&gt;2&lt;/sup&gt;, Ketut Agus Adrianta&lt;sup&gt;3&lt;/sup&gt;, Karnita Yuniarti&lt;sup&gt;4&lt;/sup&gt;, Muthmainnah Muthmainnah&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Forestry, Faculty of Forestry, Tadulako University, Palu, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmaceutics, Faculty of Pharmacy, Universitas Mahasaraswati Denpasar, Bali, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Mahasaraswati Denpasar, Bali, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Research Center for Biomass and Bioproduct, National Research and Innovation Agency of Indonesia, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ferdy Salamat</style></author><author><style face="normal" font="default" size="100%">Anwar Daud</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Does Land-Use Associate with Escherichia coli Pollution in Karst  Springs? A Review of the Literature</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Escherichia coli</style></keyword><keyword><style  face="normal" font="default" size="100%">Karst Springs</style></keyword><keyword><style  face="normal" font="default" size="100%">Land-Use</style></keyword><keyword><style  face="normal" font="default" size="100%">Pollution</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">1250-1253</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The presence of &lt;em&gt;Escherichia coli &lt;/em&gt;bacteria in karst springs, influenced by land cover conditions and land use activities in rainwater catchment areas, indicates a decrease in water quality. The study aimed to describe the effect of land use on &lt;em&gt;Escherichia&lt;/em&gt; &lt;em&gt;coli &lt;/em&gt;contamination in karst springs.&lt;strong&gt; Methods: &lt;/strong&gt;This was a narrative review retrieving studies from Scopus and PubMed databases. The keywords used are pollution, &lt;em&gt;Escherichia coli,&lt;/em&gt; land use, and karst springs. Of the 52 studies identified in the search phase, ten studies were eligible for inclusion in this review. &lt;strong&gt;Results:&lt;/strong&gt; The concentration of &lt;em&gt;Escherichia coli &lt;/em&gt;increases with increasing rainfall in all types of land use, such as forested land, mixed garden land, residential land, and grazing or livestock land. Factors that cause concentration &lt;em&gt;Escherichia coli &lt;/em&gt;does not meet water quality standards due to feces from wild animals, feces-contaminated fertilization, construction of non-water impermeable septic tanks, and feces from livestock grazing. &lt;strong&gt;Conclusions:&lt;/strong&gt; Repairing septic tanks and sewage in areas with high population density may reduce &lt;em&gt;Escherichia coli &lt;/em&gt;contamination. Further research is needed to formulate strategies and policies for managing springs in the karst areas.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">1250</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Ferdy Salamat&lt;sup&gt;1,*&lt;/sup&gt;, Anwar Daud&lt;sup&gt;2&lt;/sup&gt; , Anwar Mallongi&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Doctoral Program, School of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Faculty of Public Health, Hasanuddin University, INDONESIA. 3 Banggai Islands District Environmental Office, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ruqiah Ganda Putri Panjaitan</style></author><author><style face="normal" font="default" size="100%">Titin</style></author><author><style face="normal" font="default" size="100%">Yohanes Gatot Sutapa Yuliana</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Description of Acute Toxicity of Ketepeng Root Extract (Senna alata (L.) Roxb.)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acute toxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Fabaceae</style></keyword><keyword><style  face="normal" font="default" size="100%">Roots of Senna alata (L.) Roxb</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">393-401</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;People in Indonesia, especially in the West Kalimantan region often use the root of &lt;em&gt;ketepeng&lt;/em&gt; as a medicine to treat jaundice, but they lack knowledge regarding the appropriate dosage. Therefore, this study aims to determine the acute toxicity of &lt;em&gt;ketepeng&lt;/em&gt; root extract. &lt;strong&gt;Methods:&lt;/strong&gt; The sample population consists of 8 male mice, which were randomly divided into 4 treatment groups, namely P1, P2, P3, and P4 with dosages of 0.56 mg, 5.6 mg, 56 mg, and 560 mg/20 g body weight, respectively. The extract was administered once, after which the samples were observed for 24 hours to record the number of deaths. Follow-up observations were then carried out for 3 days on the mice that survived the test. &lt;strong&gt;Results: &lt;/strong&gt;The results showed that within 24 hours of administration, the samples in P1 were alive, while all animals in the other groups died. Furthermore, the follow-up observations on animals that survived showed that they were in good condition with no toxic symptoms, such as balance disorders, refusal to eat, and lack of physical activity. &lt;strong&gt;Conclusion:&lt;/strong&gt; Based on the results, the administration of 0.56 mg/20 g body weight of the extract was relatively safe, while higher doses can cause death. However, further testing must be carried out to complete the toxicity information as well as to determine the exact dosage range to avoid mortality during the treatment.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><accession-num><style face="normal" font="default" size="100%">21</style></accession-num><section><style face="normal" font="default" size="100%">393</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ruqiah Ganda Putri Panjaitan&lt;sup&gt;1,*&lt;/sup&gt;, Titin&lt;sup&gt;1&lt;/sup&gt;, Yohanes Gatot Sutapa Yuliana&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Biology Education Department, Faculty of Teacher Training and Education, Tanjungpura University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;English Education Department, Faculty of Teacher Training and Education, Tanjungpura University, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Madyawati Latief</style></author><author><style face="normal" font="default" size="100%">Muhaimin</style></author><author><style face="normal" font="default" size="100%">Heriyanti</style></author><author><style face="normal" font="default" size="100%">Indra Lasmana Tarigan</style></author><author><style face="normal" font="default" size="100%">Sutrisno</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determination Antioxidant Activity of Coffea Arabica, Coffea Canephora, Coffea Liberica and Sunscreens Cream Formulation for Sun Protection Factor (SPF)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Coffee</style></keyword><keyword><style  face="normal" font="default" size="100%">Cream</style></keyword><keyword><style  face="normal" font="default" size="100%">SPF</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">335-342</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Coffee is a highly consumed and popular beverage consumed in many countries. Its ingredients have a powerful antioxidant capacity and have the potential as sunscreen to protect the skin. This study aimed to examine the antioxidant activity of Arabica, robusta and liberica coffee extracts and the SPF activity of the coffee extract cream formulation. Coffee were macerated with three types of solvents with polarity gradients. The fraction of each coffee was analyzed for antioxidant activity using DPPH and formulated into the cream. Furthermore, the cream was analyzed for its SPF activity. The results of this study indicated that the methanol fraction of Robusta and Arabica coffee has the best antioxidant activity with IC50 values of 8.98 (ppm) and 13.13, respectively. Meanwhile, Liberica coffee has the best antioxidant in the ethyl acetate fraction, IC&lt;sub&gt;50&lt;/sub&gt; = 10.90 (ppm). In addition, the best SPF values for Robusta, Liberica and Arabica coffees were found in F3 cream with the category of Very Good Protection; 36.087 ± 0.0005; 35.007 ± 0.0005; 36,867 ± 0.0005 respectively.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><section><style face="normal" font="default" size="100%">335</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Madyawati Latief&lt;sup&gt;1,2&lt;/sup&gt;, Muhaimin&lt;sup&gt;3&lt;/sup&gt;, Heriyanti&lt;sup&gt;1,2&lt;/sup&gt;, Indra Lasmana Tarigan&lt;sup&gt;1,2&lt;/sup&gt;, Sutrisno&lt;sup&gt;1,2&lt;/sup&gt;,&lt;sup&gt;*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Chemistry, Faculty of Science and Technology, Universitas Jambi, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;The University Center of Excellence, E2- KOLIM, Universitas Jambi, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjajaran, Bandung, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">B Halim</style></author><author><style face="normal" font="default" size="100%">RA Syahputra</style></author><author><style face="normal" font="default" size="100%">I Adenin</style></author><author><style face="normal" font="default" size="100%">HP Lubis</style></author><author><style face="normal" font="default" size="100%">F Mendrofa</style></author><author><style face="normal" font="default" size="100%">S Lie</style></author><author><style face="normal" font="default" size="100%">SE Nugraha</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determination of Phytochemical Constituent, Antioxidant Activity, Total Phenol and Total Flavonoid of Extract Ethanol Phyllanthus emblica Fruit</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">63-67</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Phyllanthus emblica &lt;/em&gt;(PE) is a plant that grows widely in Indonesia, particularly on Sumatra island. In India, it is known as Indian gooseberry and is frequently used in ayurvedic medicine. PE fruit is well-known for its high antioxidant activity and a variety of pharmacological properties. The purpose of this study was to ascertain the phytochemical composition, antioxidant activity, total phenol, and total flavonoid concentrations. &lt;strong&gt;Methods:&lt;/strong&gt; The fruits were harvested in the Indonesian town of Padang Sidimpuan. Up to 700 g of dry PE fruit powder was dissolved in 96 percent ethanol and macerated for seven days, with periodic steering daily. The solution was then filtered using Whatman paper no 1, and the filtered result was evaporated under reduced pressure using a rotary evaporator until a crude extract/ethanol extract of PE (EEPE) was obtained, and the phytochemical constituents, antioxidant activity, total phenol, and flavonoid were analysed. &lt;strong&gt;Results&lt;/strong&gt;: The result shows that EEPE contains some flavonoids such as quercetine, betaine, Trigonelline, Myricitrin, Myricetin, Leucine, and Kaempferol. EEPE as an antioxidant of 7.626 ± 0.41 μg/dL. It shows that the antioxidant activity of the ethanol extract of &lt;em&gt;Phyllanthus emblica&lt;/em&gt; is strong ethanol extract of &lt;em&gt;Phyllanthus emblica &lt;/em&gt;contains Total Flavonoid was 5.816 ± 2.81(mg QE/g extract) and total phenol was 274.590 ± 13.61(mg GAE/g extract). &lt;strong&gt;Conclusions&lt;/strong&gt;: In summary, extract ethanol of Pyllanthus emblica contains flavonoid and have antioxidant activity and high total phenol and flavonoid levels.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Key words&lt;/strong&gt;: Antioxidant, Total flavonoid, Total phenol, Phyllanthus emblica..&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">63</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;B Halim&lt;sup&gt;1,3&lt;/sup&gt;, RA Syahputra&lt;sup&gt;2,*&lt;/sup&gt;, I Adenin&lt;sup&gt;3&lt;/sup&gt;, HP Lubis&lt;sup&gt;3&lt;/sup&gt;, F Mendrofa&lt;sup&gt;4&lt;/sup&gt;, S Lie&lt;sup&gt;5&lt;/sup&gt;, SE Nugraha&lt;sup&gt;6&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Medicine, Universitas Prima Indonesia, Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Klinik Riyena Orthomedik, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Akademi Keperawatan Colombia Asia, Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Sumatera Utara, Sumatera Utara, Medan, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Emranul Kabir</style></author><author><style face="normal" font="default" size="100%">M. R. O. Khan Noyon</style></author><author><style face="normal" font="default" size="100%">Md. Amjad Hossain</style></author><author><style face="normal" font="default" size="100%">Pranta Acharjee</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">DFT and Pharmacokinetic Study of Some Heterocyclic Aspirin Derivatives as The Cyclooxygenase Inhibitors: An In-Silico Approach</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">ADMET.</style></keyword><keyword><style  face="normal" font="default" size="100%">Aspirin</style></keyword><keyword><style  face="normal" font="default" size="100%">DFT</style></keyword><keyword><style  face="normal" font="default" size="100%">Heterocyclic compound</style></keyword><keyword><style  face="normal" font="default" size="100%">Molecular docking</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">1005-1021</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Ibuprofen and aspirin are frequently used to relieve inflammation, pain, and fever. These are the two most significant non-steroidal and anti-inflammatory drugs (NSAIDs). They prevent the development of prostaglandin by blockampounds have been assessed by ibuprofen as well as quantum mechanical computations. Density functional theory (DFT) with the B3LYP/6-31G+ basis function has been used to elucidate the thermo-chemical, molecular orbital, and optimum geometrical aspects in the gas phase. Using molecular docking and non-bonding interactions, the binding affinities and behaviors of some heterocyclic aspirin analogs have been studied on human cyclooxygenase (COX-1 as well as COX-2) proteins (6Y3C and 5F19). The chemical stability of all structures is supported by geometry and thermo-chemical findings. In contrast to aspirin and ibuprofen, almost all tested analogs exhibited a substantial binding score to the receptor protein (5F19). The ADMET prediction revealed the enhanced pharmacokinetic properties of some derivatives with less acute oral toxicity. Overall, eight heterocyclic aspirin analogues 2-9 were shown to be more effective in inhibiting Cyclooxygenase-2 (5F19) than Cyclooxygenase-1 (6Y3C), indicating that they may be effective as COX-2-related inflammation therapeutic candidates.&lt;/p&gt;
&lt;quillbot-extension-portal&gt;&lt;/quillbot-extension-portal&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Research Article </style></work-type><section><style face="normal" font="default" size="100%">1005</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Emranul Kabir&lt;sup&gt;1, 2,*&lt;/sup&gt;, M. R. O. Khan Noyon&lt;sup&gt;1&lt;/sup&gt;, Md. Amjad Hossain&lt;sup&gt;1&lt;/sup&gt;, Pranta Acharjee&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Science, Department of Chemistry, University of Chittagong, Chittagong, 4331, BANGLADESH.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Electrical and Electronic Engineering, International Islamic University Chittagong, Chittagong, 4318, BANGLADESH.&lt;/p&gt;
&lt;quillbot-extension-portal&gt;&lt;/quillbot-extension-portal&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Etty Hary Kusumastuti</style></author><author><style face="normal" font="default" size="100%">Priangga Adi Wiratama</style></author><author><style face="normal" font="default" size="100%">Grace Ariani</style></author><author><style face="normal" font="default" size="100%">Stephanie Natasha Djuanda</style></author><author><style face="normal" font="default" size="100%">Alphania Rahniayu</style></author><author><style face="normal" font="default" size="100%">Nila Kurniasari</style></author><author><style face="normal" font="default" size="100%">Dyah Fauziah</style></author><author><style face="normal" font="default" size="100%">Anny Setijo Rahaju</style></author><author><style face="normal" font="default" size="100%">Isnin Anang Marhana</style></author><author><style face="normal" font="default" size="100%">Alfian Nur Rosyid</style></author><author><style face="normal" font="default" size="100%">Dwi Wahyu</style></author><author><style face="normal" font="default" size="100%">Gilang Muhammad Setyo Nugroho</style></author><author><style face="normal" font="default" size="100%">Adhitri Anggoro</style></author><author><style face="normal" font="default" size="100%">I Komang Rusgi Yandi</style></author><author><style face="normal" font="default" size="100%">Bambang Pujo Semedi</style></author><author><style face="normal" font="default" size="100%">Jilientasia Godrace Lilihata</style></author><author><style face="normal" font="default" size="100%">Ummi Maimunah</style></author><author><style face="normal" font="default" size="100%">Supriadi</style></author><author><style face="normal" font="default" size="100%">Achmad Lefi</style></author><author><style face="normal" font="default" size="100%">Lalu Galih Pratama Rinjani</style></author><author><style face="normal" font="default" size="100%">Edi Suyanto</style></author><author><style face="normal" font="default" size="100%">Ricardo Ardian Nugraha</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Differences in interleukin-6 and interleukin-17 expression in covid-19 post-mortem lung tissue biopsy compared with noncovid- 19</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Biopsy</style></keyword><keyword><style  face="normal" font="default" size="100%">COVID-19</style></keyword><keyword><style  face="normal" font="default" size="100%">IL-17</style></keyword><keyword><style  face="normal" font="default" size="100%">IL-6</style></keyword><keyword><style  face="normal" font="default" size="100%">Post mortem lung tissue.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">887-892</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; COVID-19 has spread rapidly around the world. It is necessary to study lung tissue of postmortem COVID19 patients to determine the molecular alteration particularly the role of IL-6 and IL-17 in causing fatality. &lt;strong&gt;Objective:&lt;/strong&gt; This study aims to determine the differences in the expressions of IL-6 and IL-17 in lung tissue of post-mortem COVID-19 patients compared to non-COVID-19 patients. This study also aimed to analyze the correlation between the expressions of IL-6 and IL-17 in lung tissue of post-mortem COVID-19 patients. Methods: This research is an observational analytic study with crosssectional approach. The samples were 15 paraffin blocks of post-mortem lung tissue biopsy of COVID-19 patients, and 15 paraffin blocks of inflammatory lung tissue biopsy or surgery of non-COVID-19 patients. IL-6 and IL-17 expressions were evaluated by immunohistochemical procedure. &lt;strong&gt;Result: &lt;/strong&gt;There was a significant difference in the expression of IL-6 in the COVID-19 group and the non-COVID-19 group with a p-value = 0.001 (p &amp;lt; 0.05). There was a significant difference in the expression of IL-17 in the COVID-19 group and the non-COVID-19 group with p-value = 0.001 (p &amp;lt; 0.05). There was a significant correlation between the expressions of IL-6 and IL-17 in the COVID-19 group, with the Spearman coefficient value (rs) of 0.548 with p = 0.034 (p &amp;lt; 0.05).&lt;strong&gt; Conclusion:&lt;/strong&gt; There are differences in the expression of IL-6 and IL-17 between COVID-19 and non-COVID-19 lung tissue. There is a significant correlation between the expressions of IL-6 and IL-17 in post-mortem lung tissue of COVID-19 patients.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><section><style face="normal" font="default" size="100%">887</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Etty Hary Kusumastuti&lt;sup&gt;1,*&lt;/sup&gt;, Priangga Adi Wiratama&lt;sup&gt;1&lt;/sup&gt;, Grace Ariani&lt;sup&gt;1&lt;/sup&gt;, Stephanie Natasha Djuanda&lt;sup&gt;1&lt;/sup&gt;, Alphania Rahniayu&lt;sup&gt;1&lt;/sup&gt;, Nila Kurniasari&lt;sup&gt;1&lt;/sup&gt;, Dyah Fauziah1, Anny Setijo Rahaju&lt;sup&gt;1&lt;/sup&gt;, Isnin Anang Marhana&lt;sup&gt;2&lt;/sup&gt;, Alfian Nur Rosyid&lt;sup&gt;2&lt;/sup&gt;, Dwi Wahyu&lt;sup&gt;2&lt;/sup&gt;, Gilang Muhammad Setyo Nugroho&lt;sup&gt;2&lt;/sup&gt;, Adhitri Anggoro&lt;sup&gt;2&lt;/sup&gt;, I Komang Rusgi Yandi&lt;sup&gt;2&lt;/sup&gt; Bambang Pujo Semedi&lt;sup&gt;3&lt;/sup&gt;, Jilientasia Godrace Lilihata&lt;sup&gt;3&lt;/sup&gt;, Ummi Maimunah&lt;sup&gt;4&lt;/sup&gt;, Supriadi&lt;sup&gt;4&lt;/sup&gt;, Achmad Lefi&lt;sup&gt;5&lt;/sup&gt;, Lalu Galih Pratama Rinjani&lt;sup&gt;5&lt;/sup&gt;, Edi Suyanto&lt;sup&gt;6&lt;/sup&gt;, Ricardo Ardian Nugraha&lt;sup&gt;6&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Anatomical Pathology, Faculty of Medicine, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Anesthesiology and Reanimation, Faculty of Medicine, Universitas Airlangga University – Dr. Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Forensics and Medicolegal Medicine, Faculty of Medicine, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Silvia W Lestari</style></author><author><style face="normal" font="default" size="100%">Khairunnisa F Ilato</style></author><author><style face="normal" font="default" size="100%">M. Iqbal A Pratama</style></author><author><style face="normal" font="default" size="100%">Husna Qonitah</style></author><author><style face="normal" font="default" size="100%">Gito Wasian</style></author><author><style face="normal" font="default" size="100%">Amandanu Bramantya</style></author><author><style face="normal" font="default" size="100%">Firda A Husna</style></author><author><style face="normal" font="default" size="100%">Ria Margiana</style></author><author><style face="normal" font="default" size="100%">Gita Pratama</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Does Soybean (Glycine max) Supplementation Increase Oocyte Viability, Decrease Oocyte Apoptosis and Improve Embryo Development Quality? An Experimental Study</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">133-140</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; One of the important factors in Assisted Reproductive Technology (ART) is embryo quality that depends on oocyte quality. Maternal nutrition in form of soybean supplementation is thought to have benefits in oocyte quality. To determine the effect soybean supplementation to the embryo quality from oocyte side. &lt;strong&gt;Methods: &lt;/strong&gt;This experimental study involved female mice from Swiss strain aged 6 weeks that were divided into two groups, group with soybean (soybean group/SG) and group without soybeans (pellet group/PG). Follicles were collected and denuded to get oocytes. The oocytes were stained with MitoTracker for assessing the mitochondrial membrane potential and TUNEL for assessing the apoptotic level. Colour intensity was assessed using a confocal microscope and determined using ImageJ software. Sperms were extracted surgically from the epididymis-vas deferens and performed preparation prior to intra cytoplasmic sperm injection (ICSI) procedure. Then, the embryos were cultured and observed for the quality. &lt;strong&gt;Result&lt;/strong&gt;: In TUNEL test, the average colour intensity of the SG was lower compared to the PG, significantly (p=0.03). While in the Mito Tracker test, the average colour intensity for the SG was higher compared to PG, not significantly (p=1.08). In addition, the embryo development on Day-1 and Day-3 showed more good embryo quality of SG compared to PG, significantly (p=0.03). &lt;strong&gt;Conclusion&lt;/strong&gt;: Soybean supplementation improved embryo quality at the cleavage stage by decreasing apoptosis of the oocytes rather than increasing the viability the oocytes.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Key words&lt;/strong&gt;: Oocyte, Soybean, Apoptosis, Embryo development, Embryo quality.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">133</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Silvia W Lestari&lt;sup&gt;1,*&lt;/sup&gt;, Khairunnisa F Ilato&lt;sup&gt;2&lt;/sup&gt;, M. Iqbal A Pratama&lt;sup&gt;2&lt;/sup&gt;, Husna Qonitah&lt;sup&gt;3&lt;/sup&gt;, Gito Wasian&lt;sup&gt;1&lt;/sup&gt;, Amandanu Bramantya&lt;sup&gt;2&lt;/sup&gt;, Firda A Husna&lt;sup&gt;4&lt;/sup&gt;, Ria Margiana&lt;sup&gt;5&lt;/sup&gt;, Gita Pratama&lt;sup&gt;6&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Medical Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Undergraduate Study of Medicine of Faculty Medicine, Universitas INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Undergraduate Study of Biology of Faculty Mathematics and Natural Science, Universitas INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Master’s programme in biomedical medicine of Faculty Medicine, Universitas INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Obstetry &amp;amp; Gynecology, Faculty of Medicine, Universitas Indonesia – Ciptomangunkusumo Hospital, Jakarta, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Pathom Somwong</style></author><author><style face="normal" font="default" size="100%">Chomnapas Chuchote</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determination of Lupeol, a Cytotoxic Compound Against SW620 Cells in the Extracts of Ha-Rak Recipe</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Benchalokawichian</style></keyword><keyword><style  face="normal" font="default" size="100%">Cancer Cell Lines</style></keyword><keyword><style  face="normal" font="default" size="100%">Cytotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Ha-Rak</style></keyword><keyword><style  face="normal" font="default" size="100%">Lupeol</style></keyword><keyword><style  face="normal" font="default" size="100%">MTT</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">133-138</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Ha-Rak is an herbal recipe that has been stated by Ministry of Public Health, Thailand to utilize as the herbal medicines for the treatment of fever. The recipe comprises the roots of five plants including&lt;em&gt; Capparis micracantha, Clerodendrum indicum, Ficus racemosa, Harrisonia perforata&lt;/em&gt; and&lt;em&gt; Tiliacora triandra&lt;/em&gt; as its ingredients. &lt;strong&gt;Methods:&lt;/strong&gt; The extracts of Ha-Rak and its five herbal principles were evaluated for their potential on the cytotoxicity against SW620 cancer cell lines using the MTT assay and an active compound, lupeol which was found as a cytotoxic compound in the herbal ingredients of Ha-Rak was further determined. A chromatographic method for investigating that compound in the extracts was developed herein. The analytical method comprised a cholesterol-coated C18 column, a mixture of acetonitrile and methanol (70:30) with a flow rate of 2 mL/min, and a diode-array UV wavelength at 210 nm as a stationary phase, mobile phase, and detector, respectively. &lt;strong&gt;Results: &lt;/strong&gt;The amount of lupeol in the extracts of Ha-Rak and the herbal principles, which possessed cytotoxicity against SW620 cell lines with the IC&lt;sub&gt;50 &lt;/sub&gt;values of 30.10-212.24 μg/mL displayed variously in the range of 4.50-250.62 mg/100g. The difference of the contents among the extracts was noted significantly (&lt;em&gt;P &lt;/em&gt;&amp;lt; 0.05). The correlation between the lupeol contents and their cytotoxic performances on the tested cell lines was observed in our investigation. &lt;strong&gt;Conclusion: &lt;/strong&gt;Our findings demonstrated that Ha-Rak recipe contains a promising cytotoxic compound, lupeol and it will support the recipe to subject further pharmacological studies on anticancer activity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">133</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Pathom Somwong&lt;sup&gt;1,&lt;/sup&gt;*, Chomnapas Chuchote&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Chemistry, College of Pharmacy, Rangsit University, Pathumthani, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy, College of Pharmacy, Rangsit University, Pathumthani, THAILAND.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vidya Gowdappa Doddawad</style></author><author><style face="normal" font="default" size="100%">B.M. Gurupadayya</style></author><author><style face="normal" font="default" size="100%">Shivananda S</style></author><author><style face="normal" font="default" size="100%">Vidya CS</style></author><author><style face="normal" font="default" size="100%">Azhar Mohammed</style></author><author><style face="normal" font="default" size="100%">Bhuyan L</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determination of Urinary Methyl Hippuric Acid Using Shimadzu UV-Visible Spectrophotometer Among Petroleum Employees</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Occupational Exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">Urine Methyl Hippuric Acid Level</style></keyword><keyword><style  face="normal" font="default" size="100%">UV Spectrophotometry</style></keyword><keyword><style  face="normal" font="default" size="100%">Xylene</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1277-1281</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Xylene is a significant part of petroleum and a broadly considered as a natural impure material. About 98% of Xylene is extracted from the petrochemical and petrol refining factories. It is one of the major genotoxicant part in petroleum, which may initiate various diseases but malignancy is questionable. Taking into consideration, we intend to identify the urinary methyl hippuric acid level which is metabolic product of xylene among petroleum station employees as well as in healthy persons. &lt;strong&gt;Aims and Objectives:&lt;/strong&gt; To identify the occupational exposure of xylene in petrol station employees by assessing urinary methyl hippuric acid level. To determine and compare the level of urinary methyl hippuric acid among healthy individuals and petrol station employees. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Urine samples were collected from 30 healthy individual (control) and 30 petroleum employees (case) working in petroleum station who are above 18 years of age. The urinary methyl hippuric acid (MHA) level was analysed by using Shimadzu UV-Visible Spectrophotometer method.&lt;strong&gt; Results: &lt;/strong&gt;The urinary Methyl hippuric acid level was significantly higher in petroleum station employees than in healthy individuals (p&amp;lt;0.001). &lt;strong&gt;Conclusion:&lt;/strong&gt; The urinary MHA level is a helpful tool to identify the occupational exposure of people who work in petrol and petroleum product. Subsequently, our investigation accentuates that proper precautionary measure and efficiently bio-observing should be taken among petrol station employees which will assist with reducing their likely degrees of risk related with the occupation. It might start the cancer-causing disease through the cellular DNA changes and induce genotoxic effects.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1277</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Vidya Gowdappa Doddawad&lt;sup&gt;1,&lt;/sup&gt;*, B.M. Gurupadayya&lt;sup&gt;2&lt;/sup&gt;, Shivananda S&lt;sup&gt;1&lt;/sup&gt;, Vidya CS&lt;sup&gt;3&lt;/sup&gt;, Azhar Mohammed&lt;sup&gt;4&lt;/sup&gt;, Bhuyan L&lt;sup&gt;5&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;JSS Dental College and Hospital, Mysuru – 570022, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;JSS College of Pharmacy, Mysuru – 570015, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;JSS medical College and Hospital, Mysuru – 570022, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;A.B. Shetty Memorial Institute of Dental Sciences, Mangalore, INDIA. 5Kalinga Institute of Dental Sciences, Bhubaneswar, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Monika Bhalodiya</style></author><author><style face="normal" font="default" size="100%">Jayant Chavda</style></author><author><style face="normal" font="default" size="100%">Nilesh Patel</style></author><author><style face="normal" font="default" size="100%">Ravi Manek</style></author><author><style face="normal" font="default" size="100%">Ajay Patel</style></author><author><style face="normal" font="default" size="100%">Sheetal Faldu</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determination of Polyphenolic content and Antioxidant Activity from Various Extracts of Boerhaavia diffusa Linn Root: An in vitro Approach for Selection of Appropriate Extracting Solvent</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">ABTS</style></keyword><keyword><style  face="normal" font="default" size="100%">Boerhavia diffusa</style></keyword><keyword><style  face="normal" font="default" size="100%">crude extract</style></keyword><keyword><style  face="normal" font="default" size="100%">DPPH</style></keyword><keyword><style  face="normal" font="default" size="100%">Free radicles</style></keyword><keyword><style  face="normal" font="default" size="100%">total phenolic content</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1578-1585</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; This study is aimed to evaluate extraction capacity of different solvents (toluene, dichloromethane, chloroform, ethyl acetate, ethanol, methanol, water, 60% aqueous methanol, 60% aqueous ethanol and 60% aqueous acetone) and its effect on total phenolic content, total flavonoid content, and antioxidant assay. &lt;strong&gt;Methods: &lt;/strong&gt;Extraction was performed from dried root powder of &lt;em&gt;Boerhavia diffusa&lt;/em&gt; using various solvents at 25˚C on magnetic sirr (300 rpm). Extraction yield, total phenolic content, total flavonoid content and total tannin content of the extracts were determined spectrophotometrically using gallic acid, quercetin as standards. Antioxidant potential determines by using various in vitro methodologies such as DPPH, FRAP, and ABTS assay. &lt;strong&gt;Result: &lt;/strong&gt;The 60% aqueous methanol showed the highest extracting yield, in contrast, toluene and hexane showed the lowest yield. Highest total phenolic content (239.8±0.25 mg GAE/g) and total flavonoid content (131.1±4.20 mg QCE/g), were found from methanolic extract. While, acetone extract showed highest tannin content. The Methanolic extract of &lt;em&gt;Boerhaavia diffusa&lt;/em&gt; exhibited the highest antioxidant activity. &lt;strong&gt;Conclusions: &lt;/strong&gt;The highest correlation was found between phenolic content and the antioxidant assay. It seems that phenolic contents are responsible for free radicle scavenging activity. From the observation, it concluded that methanolic extract rich with polyphenolic content and acetone extract showed the highest amount of tannin content.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1578</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Monika Bhalodiya&lt;sup&gt;1,&lt;/sup&gt;*, Jayant Chavda&lt;sup&gt;2&lt;/sup&gt;, Nilesh Patel&lt;sup&gt;2&lt;/sup&gt;, Ravi Manek&lt;sup&gt;2&lt;/sup&gt;, Ajay Patel&lt;sup&gt;2&lt;/sup&gt;, Sheetal Faldu&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Gujarat Technological University, Chandkheda, Ahmedabad, Gujarat 382424, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;B.K Mody Government Pharmacy College, Rajkot, Gujarat 360003, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Smt. R. D. Gardi B. Pharmacy College, Rajkot 360005, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Bokov DO</style></author><author><style face="normal" font="default" size="100%">Sergunova EV</style></author><author><style face="normal" font="default" size="100%">Marakhova AI</style></author><author><style face="normal" font="default" size="100%">Morokhina SL</style></author><author><style face="normal" font="default" size="100%">Plakhotnaia ON</style></author><author><style face="normal" font="default" size="100%">Krasnyuk II</style></author><author><style face="normal" font="default" size="100%">Bessonov VV</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determination of Sugar Profile in Viburnum Fruits and its Dosage Forms by HPLC-RID</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Guelder-rose</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC-RID</style></keyword><keyword><style  face="normal" font="default" size="100%">Monomeric carbohydrates</style></keyword><keyword><style  face="normal" font="default" size="100%">Viburnum fruits</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February  2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">103-108</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; In the Russian Federation, the viburnum fruits are used to obtain infusions and syrups as medications. This medicinal herbal raw material contains a large number of biologically active substances: vitamins, anthocyanins, proanthocyanidins, flavonoids, hydroxycinnamic acids, iridoids, carbohydrates, organic acids, lipids etc. The research aimed to study one of the biologically active substances group responsible for the formation of the organoleptic properties of aqueous extracts–monomeric carbohydrate composition and content. &lt;strong&gt;Materials and methods:&lt;/strong&gt; Dried viburnum (guelder-rose) fruits, an aqueous infusion based on it, and viburnum syrup of industrial manufacture (Russia) were purchased from the pharmacy and prepared for research. For HPLC analysis of monomeric sugars Agilent 1260 Series HPLC system equipped with autosampler/injector, four-channel gradient pump, column thermostat, refractive index detector), software (ChemStation Version B.01), column (Waters Sugar-Pack I, 10 μm, 300 × 6.5 mm) were used. Isocratic elution was performed using purified water (with the addition of Ca-EDTA 0.05 mg/ml) as the mobile phase, at a flow rate of 0.5 mL/min. The column was maintained at 80°C, the refractive index detector – at 35°C. The injection volume was 10 μL, analysis time – 20 min. &lt;strong&gt;Results: &lt;/strong&gt;The main free carbohydrates of viburnum fruits and preparations based on them are glucose, fructose, and sucrose. The total content of simple sugars in the viburnum fruits is 28.393 ± 0.528%, in the infusion – 0.499 ± 0.015%, in the syrup – 69.736 ± 1.551%. The characteristic ratio of glucose: fructose: sucrose in dried viburnum fruits is 8.1:5.4:1, in infusion – 7.0:5.7:1, and in syrup – 9.2:8.8:1. The sugars' degree of passing into infusion is 74.34%. &lt;strong&gt;Conclusion: &lt;/strong&gt;The composition and content of carbohydrates determined by HPLC-RID are an important characteristic data. It can be used for viburnum fruits Russian pharmacopoeial standardization along with the quantifying total content of organic acids.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">103</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Bokov DO&lt;sup&gt;1,2,&lt;/sup&gt;*, Sergunova EV&lt;sup&gt;1&lt;/sup&gt;, Marakhova AI&lt;sup&gt;3&lt;/sup&gt;, Morokhina SL&lt;sup&gt;4&lt;/sup&gt;, Plakhotnaia ON&lt;sup&gt;1&lt;/sup&gt;, Krasnyuk II&lt;sup&gt;1&lt;/sup&gt; (junior), Bessonov VV&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Institute of Pharmacy, Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, Moscow, 119991, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of Food Chemistry, Federal Research Center for Nutrition, Biotechnology and Food Safety, 2/14 Ustyinsky pr., Moscow, 109240, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Institute of Biochemical Technology and Nanotechnology, Рeoples’ Friendship University of Russia (RUDN University), 6, Miklukho-Maklaya Street, Moscow, 117198, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Preparatory faculty, Financial University under the Government of the Russian Federation (Financial University), 55, Leningradsky Prospekt, Moscow, 125057, RUSSIAN FEDERATION.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Zaichikova SG</style></author><author><style face="normal" font="default" size="100%">Bokov DO</style></author><author><style face="normal" font="default" size="100%">Kiselevskii MV</style></author><author><style face="normal" font="default" size="100%">Antsyshkina AM</style></author><author><style face="normal" font="default" size="100%">Bondar AA</style></author><author><style face="normal" font="default" size="100%">Prostodusheva TV</style></author><author><style face="normal" font="default" size="100%">Shchepochkina OYu</style></author><author><style face="normal" font="default" size="100%">Gegechkori VI</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determination of the Chemical Composition of Lady’s Bedstraw (Galium verum L.) Herb Extract by GC-MS</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ethanol Extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Galium verum L.</style></keyword><keyword><style  face="normal" font="default" size="100%">Gas chromatography-mass spectrometry</style></keyword><keyword><style  face="normal" font="default" size="100%">Lady’s bedstraw</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">857-863</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;The research is devoted to the study of the Lady’s bedstraw (&lt;em&gt;Galium verum&lt;/em&gt; L.) herb ethanol extract composition using the method of gas chromatography with mass spectrometric detection. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;Air-dried &lt;em&gt;G. verum&lt;/em&gt; L. herb was used for ethanol extract preparation. Hewlett Packard 6890, 5973A GC/MSD System equipped with an HP-5MS quartz capillary column with geometric dimensions of 30 m×0.25 mm×0.25 μm was used for GC-MS analysis. &lt;strong&gt;Results: &lt;/strong&gt;It was established that the Lady’s bedstraw ethanol extract is rich in biologically active substances that determine its wide spectrum of pharmacological action. 15 compounds were identified by comparing with library mass spectra. &lt;strong&gt;Conclusions: &lt;/strong&gt;&lt;em&gt;G. verum&lt;/em&gt; L. is a promising source of crude herbal drugs. In the future, after additional pharmacognostic studies, &lt;em&gt;G. verum&lt;/em&gt; L. herb can be recommended for implementation in the State Pharmacopeia of the Russian Federation.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">857</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Zaichikova SG&lt;sup&gt;1&lt;/sup&gt;, Bokov DO&lt;sup&gt;1,2,&lt;/sup&gt;*, Kiselevskii MV&lt;sup&gt;3&lt;/sup&gt;, Antsyshkina AM&lt;sup&gt;1&lt;/sup&gt;, Bondar AA&lt;sup&gt;1&lt;/sup&gt;, Prostodusheva TV&lt;sup&gt;1&lt;/sup&gt;, Shchepochkina OYu&lt;sup&gt;1&lt;/sup&gt;, Gegechkori VI&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;A.P. Nelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, Moscow, 119991, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Laboratory of Food Chemistry, Federal Research Center of Nutrition, Biotechnology and Food Safety, 2/14 Ustyinsky pr., Moscow, 109240, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Laboratory of Cell-Mediated Immunity, Blokhin National Medical Research Center of Oncology, 24, Kashirskoye sh., Moscow, 115478, RUSSIAN FEDERATION.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Zulfiayu Sapiun</style></author><author><style face="normal" font="default" size="100%">Paulus Pangalo</style></author><author><style face="normal" font="default" size="100%">Arlan K Imran</style></author><author><style face="normal" font="default" size="100%">Prisca Safriani Wicita</style></author><author><style face="normal" font="default" size="100%">Rizka Puji Astuti Daud</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determination of Total Flavonoid Levels of Ethanol Extract Sesewanua Leaf (Clerodendrum Fragrans Wild) With Maceration Method Using UV-Vis Spectrofotometry</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Maceration</style></keyword><keyword><style  face="normal" font="default" size="100%">Quercetin</style></keyword><keyword><style  face="normal" font="default" size="100%">Sesewanuwa</style></keyword><keyword><style  face="normal" font="default" size="100%">total flavonoid</style></keyword><keyword><style  face="normal" font="default" size="100%">UV-Vis spectrophotometry</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">356-360</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Sesewanuwa (&lt;em&gt;Clerodendrum fragrans&lt;/em&gt; Wild) is one of the plants with abundant flavonoid content in the leaves. The characteristic flavonoids with the two benzene ring groups cause the process of finding an appropriate extraction technique. &lt;strong&gt;Objective:&lt;/strong&gt; This study aims to determine the total flavonoid levels of ethanol extract of sesewanuwa leaves obtained from maceration extraction methods. &lt;strong&gt;Method: &lt;/strong&gt;This research was carried out by extracting the simplicia of sesewanuwa leaves by maceration method using 96% ethanol solvent. Comparison between the simplicia and the solvent used is 1:7, then the extract obtained was carried out with initial qualitative identification of flavonoids with simple reagents and the total flavonoid levels were determined using UV-Vis spectrophotometry. &lt;strong&gt;Results: &lt;/strong&gt;The results showed that the ethanol extract of sesewanuwa leaves obtained by maceration extraction method in qualitative and quantitative tests contained flavonoids with quercetin standard with a total content of 13.47%.This research was carried out by extracting the simplicia of sesewanuwa leaves by maceration method using 96% ethanol solvent. Comparison between the simplicia and the solvent used is 1:7, then the extract obtained was carried out with initial qualitative identification of flavonoids with simple reagents and the total flavonoid levels were determined using UV-Vis spectrophotometry. &lt;strong&gt;Conclusion: &lt;/strong&gt;The results showed that the ethanol extract of sesewanuwa leaves obtained by maceration extraction method in qualitative and quantitative tests contained flavonoids with quercetin standard with a total content of 13.47%.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">356</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Zulfiayu Sapiun&lt;sup&gt;1,&lt;/sup&gt;*, Paulus Pangalo&lt;sup&gt;2&lt;/sup&gt;, Arlan K. Imran&lt;sup&gt;1&lt;/sup&gt;, Prisca Safriyani Wicita&lt;sup&gt;1&lt;/sup&gt;, Rizka Puji Astuti Daud&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Pharmacy Department, Health Polytechnic of Gorontalo, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Nursing Department, Health Polytechnic of Gorontalo, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ferubko EV</style></author><author><style face="normal" font="default" size="100%">Rendyuk TD</style></author><author><style face="normal" font="default" size="100%">Dargaeva TD</style></author><author><style face="normal" font="default" size="100%">Nikolaev SM</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development and Evaluation of New Choleretic Agent</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Choleretic activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Choleretic herbal medicine Hexaphyte</style></keyword><keyword><style  face="normal" font="default" size="100%">Experimental damage of liver and gallbladder</style></keyword><keyword><style  face="normal" font="default" size="100%">Preclinical studies</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">962-966</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; The aim of the research is the determination of pharmacological activity during the development of the optimal way of a new choleretic agent obtaining. The multicomponent herbal medicinal product under the code name Hexaphyte (herbal multicomponent dry extract) is developed. It contains the following species of medicine plant raw materials: &lt;em&gt;Helichrysum arenarium&lt;/em&gt; L., &lt;em&gt;Tanacetum vulgare&lt;/em&gt; L., R&lt;em&gt;osa sp&lt;/em&gt;., &lt;em&gt;Urtica dioica&lt;/em&gt; L., &lt;em&gt;Mentha piperita&lt;/em&gt; L., &lt;em&gt;Glycyrrhiza glabra&lt;/em&gt; L. in the ratio of 6:2:2:2:1:1. Materials and Methods: Herbal tea was extracted three times with hot water at the temperature of 75-85ºС; water extracts were combined, filtered and dried. Hexaphyte was standardized by the content of phenolic compounds – sum of flavonoids in terms of luteolin standard and isosalipurposide standard. Phenolic compounds (flavonoids) are dominating substances (35-37%) in the obtained extract. The obtained multicomponent medicine under the code name Hexaphyte was administered per os in the experimental and therapeutic dose of 250 mg/kg to the laboratory animals having experimental induced damages of gallbladder and liver. &lt;strong&gt;Results:&lt;/strong&gt; In Hexaphyte the content of the flavonoid sum (CFS) referred to luteolin standard at a wavelength of 350 nm was not less than 4%; CFS referred to isosalipurposide standard at a wavelength of 315 nm was not less than 15%. It was revealed in the results of the realized experiments that it has a choleretic effect superior in a number of indicators to the activity of the Allochol reference drug. The pharmacotherapeutic effect of Hexaphyte at experimental damages of gallbladder and liver is due to the presence of biologically active substances, mainly of phenolic nature. &lt;strong&gt;Conclusion: &lt;/strong&gt;The obtained results of the research argue the feasibility of using the developed multicomponent medicine Hexaphyte containing biologically active substances of phenolic nature in the prevention and complex treatment of hepatobiliary system diseases.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">962</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ferubko EV&lt;sup&gt;1,&lt;/sup&gt;*, Rendyuk TD&lt;sup&gt;2&lt;/sup&gt;, Dargaeva TD&lt;sup&gt;1&lt;/sup&gt;, Nikolaev SM&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;All-Russian Research Institute of Medicinal and Aromatic Plants, Moscow, RUSSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, Moscow, 119991, RUSSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Institute of General and Experimental Biology of the Siberian Branch of the RAS, Ulan-Ude, RUSSIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Nanthakarn Woottisin</style></author><author><style face="normal" font="default" size="100%">Sumet Kongkiatpaiboon</style></author><author><style face="normal" font="default" size="100%">Sophida Sukprasert</style></author><author><style face="normal" font="default" size="100%">Korbtham Sathirakul</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development and Validation of Stability Indicating HPLC Method for Determination of Caffeic Acid, Vitexin and Rosmarinic Acid in Thunbergia laurifolia Leaf Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Force degradation</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolic compound</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical screening</style></keyword><keyword><style  face="normal" font="default" size="100%">Stabilityindicating method</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">611-618</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;em&gt;Thunbergia laurifolia &lt;/em&gt;has been a popular herb used in Thai traditional medicine for detoxification and as antipyretic. It contains rosmarinic acid (RA), caffeic acid (CA) and vitexin as major compounds. In order to control the herbal quality, the stability indicating high-performance liquid chromatography (HPLC) was developed and validated. The stability study of compounds in &lt;em&gt;T. laurifolia&lt;/em&gt; leaf extract was investigated. The chromatographic separation was performed using a reversed-phase C18 column and mobile phase consisted of 0.5% acetic acid and methanol using a gradient elution with 1.0 mL/min flow rate. The detection wavelength was set at 330 nm. The method was validated for its linearity, precision, accuracy, limit of detection and limit of quantitation. Forced degradation of three compounds in extract showed that they were stable in oxidative condition, but highly labile under alkaline hydrolytic conditions. All three compounds in &lt;em&gt;T. laurifolia &lt;/em&gt;leaf extract were stable at room temperature at least 3 months while a remarkable decrease of RA, vitexin and CA in the extract were found in accelerated condition. This finding could be applied for predicting the storage recommendation and expiry of&lt;em&gt; T. laurifolia&lt;/em&gt; extract and its related pharmaceutical products.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">611</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Nanthakarn Woottisin&lt;sup&gt;1&lt;/sup&gt;, Sumet Kongkiatpaiboon&lt;sup&gt;2&lt;/sup&gt;, Sophida Sukprasert&lt;sup&gt;1,3,&lt;/sup&gt;*, Korbtham Sathirakul&lt;sup&gt;4 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Division of Integrative Medicine, Chulabhorn International College of Medicine, Thammasat University (Rangsit Campus), Pathum Thani 12120, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Drug Discovery and Development Center, Office of Advanced Science and Technology, Thammasat University (Rangsit Campus), Pathum Thani 12120, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Protein and Proteomics Research Center for Commercial and Industrial Purposes (ProCCI), Khon Kaen University, Khon Kaen 40002, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok 10400, THAILAND.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Pornpun Laovachirasuwan</style></author><author><style face="normal" font="default" size="100%">Wutthichart Fuangbangluang</style></author><author><style face="normal" font="default" size="100%">Atchariyaporn Phanichanaphan</style></author><author><style face="normal" font="default" size="100%">Issarapong Nasomroop</style></author><author><style face="normal" font="default" size="100%">Methin Phadungkit</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Development of Phyllanthus emblica Extract in Ethosomes for Hair Loss Prevention</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Entrapment efficiency</style></keyword><keyword><style  face="normal" font="default" size="100%">Ethosomes</style></keyword><keyword><style  face="normal" font="default" size="100%">Phyllanthus emblica</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">905-910</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Hair loss is not a serious health problem but leads to decreased self- confidence, personality, and psychological problems. According to Thai traditional medical wisdom, &lt;em&gt;Phyllanthus emblica &lt;/em&gt;has the property to prevent hair loss. Ethosomes are a drug delivery system, which can increase drug delivery to deep skin layers and enhance the effectiveness of the active ingredient.&lt;strong&gt; Objective: &lt;/strong&gt;This research aims to develop ethosomes of &lt;em&gt;Phyllanthus emblica&lt;/em&gt; extract with beneficial properties. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; &lt;em&gt;Phyllanthus emblica&lt;/em&gt; was extracted by a maceration method with 95% ethanol as a solvent. The total phenolic content of the extracts was determined using the Folin-Ciocalteu method. The antioxidation activity was evaluated by DPPH assay. Ethosomes were formulated by a cold method and their properties were observed. &lt;strong&gt;Results: &lt;/strong&gt;The results showed that the total phenolic content of &lt;em&gt;Phyllanthus emblica &lt;/em&gt;extract was 406.37±2.39 mg GAE/g extract. The IC&lt;sub&gt;50&lt;/sub&gt; of antioxidant activity was 7.05±0.17 μg/ml. Ethosomes with 0.03% of &lt;em&gt;Phyllanthus emblica &lt;/em&gt;extract, 2% of soya phosphatidylcholine, and 20% of ethanol had the highest percentage of entrapment efficiency (65.26%±1.80%). The ethosomes of &lt;em&gt;Phyllanthus emblica &lt;/em&gt;extract was the spherical shape and white colloid. The particle size, polydispersity index, zeta potential, and pH of ethosomes were 0.43±0.00 μm, 0.44±0.03, -10.40±0.28 mV, and 4.06±0.03, respectively. &lt;strong&gt;Conclusion: &lt;/strong&gt;The ethosomes of &lt;em&gt;Phyllanthus emblica&lt;/em&gt; extract had good properties and area possible alternative product for hair loss prevention.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">905</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Pornpun Laovachirasuwan*, Wutthichart Fuangbangluang, Atchariyaporn Phanichanaphan, Issarapong Nasomroop, Methin Phadungkit &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Pharmacy, Mahasarakham University, Kantarawichai District, Mahasarakham 44150, THAILAND&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Skunda Diliarosta</style></author><author><style face="normal" font="default" size="100%">Rehani Ramadhani</style></author><author><style face="normal" font="default" size="100%">Dewi Indriani</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Diversity of Pteridophyta in Lubuak Mato Kuciang Padang Panjang, Sumatera Barat</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Diversity</style></keyword><keyword><style  face="normal" font="default" size="100%">Identification</style></keyword><keyword><style  face="normal" font="default" size="100%">Lubuk mato kuciang</style></keyword><keyword><style  face="normal" font="default" size="100%">Pteridophytha</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February  2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">180-185</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Padang Panjang city located at an altitude of 650 to 850 meters above sea level, so that weather cold and cool. Temperatures range from 17 °C to 26.1 °C and with 3,295 mm/ year of rainfall. This area is rich in the diversity of flora and fauna. Pteridophyta is one of the flora that has a unique diversity of species and has the potential for tremendous utilization such as ornamental plants, medicines and vegetable plants. The study was conducted in the Lubuak Mato Kuciang area of Padang Panjang City, West Sumatra, which is currently being developed for tourism. The aim of this study obtain collect data and information about the diversity of ferns in Lubuk Mato Kuciang. The activities of the study are conducted to collect species as much as possible. Identification of fern species was carried out in the Laboratory of Educational Science. Mathematics and Science Faculty. Padang State University. The identification of flora was analyzed descriptively. The identification species results were obtained through descriptive analysis. The results of this study obtains that there were 21 species of fern that include 11 families. They were namely; &lt;em&gt;Selaginellaceace&lt;/em&gt; including &lt;em&gt;Selaginella&lt;/em&gt; sp, &lt;em&gt;Selaginella plana&lt;/em&gt; Hieron and &lt;em&gt;Selaginella wildenowii&lt;/em&gt;; &lt;em&gt;Lomariopsidaceae&lt;/em&gt; family including&lt;em&gt; Neplholepisbiserrata&lt;/em&gt;; &lt;em&gt;Pterisvittata&lt;/em&gt; L; &lt;em&gt;Adiatumpedatum&lt;/em&gt;;&lt;em&gt; Cyatheaceae &lt;/em&gt;family, including &lt;em&gt;Cyatheacontaminans&lt;/em&gt;; &lt;em&gt;Gleicheinaceae &lt;/em&gt;including&lt;em&gt; Gleichenialinearis&lt;/em&gt;; &lt;em&gt;Marrattiaceae&lt;/em&gt; family including &lt;em&gt;Marrattiafraxinea&lt;/em&gt;; &lt;em&gt;Lindsaeaceae&lt;/em&gt; family including &lt;em&gt;Sphenomeris chinensis&lt;/em&gt;; and&lt;em&gt; Dryopteridaceae &lt;/em&gt;family including &lt;em&gt;Nephroletis cordifolia&lt;/em&gt;.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">180</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Kunda Diliarosta*, Rehani Ramadhani, Dewi Indriani &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Natural Sciences, Faculty of Mathematics and Natural Science, Universitas Negeri Padang, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Marissa Angelina</style></author><author><style face="normal" font="default" size="100%">Muhammad Hanafi</style></author><author><style face="normal" font="default" size="100%">Franciscus D Suyatna</style></author><author><style face="normal" font="default" size="100%">Beti Ernawati Dewi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Drug of Action Cassia Alata Leaves Extract as Antiviral to Dengue Virus Serotype-2 in vitro</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antiviral</style></keyword><keyword><style  face="normal" font="default" size="100%">Cassia alata</style></keyword><keyword><style  face="normal" font="default" size="100%">Dengue virus</style></keyword><keyword><style  face="normal" font="default" size="100%">Early step</style></keyword><keyword><style  face="normal" font="default" size="100%">Post infection</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">864-871</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background and Objectives: &lt;/strong&gt;Dengue viruses (DENV) is a mosquito-borne members of the Flaviridae family.To date, more than 2.5 billion people in over 100 countries are at risk of infection, and approximately 20 million infections were reported annually. Currently, There is no specific antiviral treatment available for DENV infection. Natural products possess a wide range of biological and biochemical potential. Among them, plants are one of the most important sources for discovering new drugs for therapy. Our previous study, showed that &lt;em&gt;Cassia alata&lt;/em&gt; has potency as antiviral to DENV, however drug of action still unclear. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; We explore the drug of action of C. alata leaves exract and its fraction through time of addition studies and effect of solvents wtih the dose based on the previous study. &lt;strong&gt;Results:&lt;/strong&gt; The most effective inhibition druf of action was determined by focus assay. Meanwhile the toxicity was measured by MTT assay. These studies demosntrated that ethanol extract of &lt;em&gt;Cassia alata&lt;/em&gt; 1 mg/ml showed strong inhibition in both early step (receptor and attachment to host cells) and post infection with inhibition 96.04 % and 99.16 %.Compared with those fractions, &lt;em&gt;Cassia alata&lt;/em&gt; ethanol extract has strongest inhibition DENV in every step of virus replication. &lt;strong&gt;Conclussion: &lt;/strong&gt;&lt;em&gt;Cassia alata&lt;/em&gt; ethanol extract has strongest inhibition DENV in every step of virus replication with the average of inhibition more than 95 %. Ethyl acetate and hexane has strongest inihibition with the average of inhibition 100 %.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">864</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Marissa Angelina&lt;sup&gt;1,2&lt;/sup&gt;, Muhammad Hanafi&lt;sup&gt;2&lt;/sup&gt;, Franciscus D. Suyatna&lt;sup&gt;3&lt;/sup&gt;, Beti Ernawati Dewi&lt;sup&gt;4,&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Doctoral Programme in Biomedical Science Faculty of Medicine, University of Indonesia, Jl. Salemba Raya 6, Jakarta 10430, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Research Centre for Chemistry LIPI , Kompleks Puspiptek Serpong 15416, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacology and Therapeutics Faculty of Medicine- RSCM Universitas Indonesia, Jl. Salemba Raya 6, Jakarta 10430, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Departement of Microbiology Faculty of Medicine, Universitas Indonesia- Cipto Mangukusumo Hospital, Jalan Pengangsaan Timur No. 16 Jakarta 10320, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gupta Shashi</style></author><author><style face="normal" font="default" size="100%">Acharya Rabinarayan</style></author><author><style face="normal" font="default" size="100%">Harisha CR</style></author><author><style face="normal" font="default" size="100%">Shukla Vinay</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Detailed Pharmacognostical and Phytochemical Screening of Stem and Stem Bark of Ficus semicordata Buch.-Ham. Ex sm. - An Extra Pharmacopoeial Drug of Ayurveda</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anukta Dravya</style></keyword><keyword><style  face="normal" font="default" size="100%">Bhu-udumbara</style></keyword><keyword><style  face="normal" font="default" size="100%">Bhuindumer</style></keyword><keyword><style  face="normal" font="default" size="100%">Extra-pharmacopoeial</style></keyword><keyword><style  face="normal" font="default" size="100%">Ficus semicordata</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1303-1311</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Stem bark of &lt;em&gt;Bhumi udumbara&lt;/em&gt; (&lt;em&gt;Ficus semicordata&lt;/em&gt; Buch.-Ham. ex Sm.) is used traditionally in the treatment of leprosy, ulcer, dysentery, wound, pregnancy, complaints of gastric, liver, bladder and various disorders. In present study, stem and stem bark of &lt;em&gt;F. semicordata&lt;/em&gt; are explored for their microscopic including powder microscopy, physiochemical and preliminary phytochemical aspects. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Stem and stem bark of the plant, after proper authentication by BSI Kolkata, were evaluated following standard procedures.&lt;strong&gt; Results: &lt;/strong&gt;Stem is hard, cylindrical, cut pieces measures about 10 - 25cm in length and 0.4 – 0.8 cm in diameter. Diagrammatic transverse section of stem shows outer cork followed by wide parenchymatous cortex with prismatic and rhomboidal crystals, starch grains and tannin content. Powder light brown in colour; odour woody; taste tasteless to astringent; texture fibrous. Stem bark is hard, single quilled after drying, outer dark reddish brown in colour with presence of lenticels, longitudinal cut fibres, rough in surface. Diagrammatic section, of the bark, shows outer several layered cork followed by cortical region along with medullary rays. Powder tortilla(brown) in colour; odour slightly aromatic; taste astringent; texture fibrous. Loss on drying at 110°C was found to be 7.41% and 8.60% of stem and stem bark respectively. HPTLC results shows 3 peaks and 0 peak at 254 and 366 nm of stem and 3 peaks at 254 and 366 nm of stem bark respectively.&lt;strong&gt; Discussion and Conclusion:&lt;/strong&gt; Woody stem and presence of brown content, tannin, rhomboidal and prismatic crystals in stem and stem bark are the diagnostic characters.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1303</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Gupta Shashi&lt;sup&gt;1&lt;/sup&gt;,*, Acharya Rabinarayan&lt;sup&gt;2&lt;/sup&gt;, Harisha CR&lt;sup&gt;3&lt;/sup&gt;, Shukla Vinay&lt;sup&gt;4 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;PhD scholar of Dravyaguna, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Professor &amp;amp; Head, Department of Dravyaguna, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Head, Pharmacognostical Laboratory, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Head, Pharmaceutical Laboratory, Institute for Post Graduate Teaching and Research in Ayurveda, Gujarat Ayurved University, Jamnagar, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sasmita Retno Sari</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Katrin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determination of Specific and Non-Specific Parameters of Simplicia and Ethanolic 70% Extract of Gadung Tubers (Dioscorea hispida)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">D. hispida</style></keyword><keyword><style  face="normal" font="default" size="100%">Gadung</style></keyword><keyword><style  face="normal" font="default" size="100%">Non-specific parameter</style></keyword><keyword><style  face="normal" font="default" size="100%">Specific parameter</style></keyword><keyword><style  face="normal" font="default" size="100%">standardization</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">759-763</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;D. hispida &lt;/em&gt;can be used as a painkiller, rheumatic drugs and antioxidant. Based on its medicinal properties,&lt;em&gt; D. hispida&lt;/em&gt; can be used as a traditional medicine that must be guaranteed on quality, safety and benefit. Therefore, standardization is needed. This aim of this study was to obtain some specific and non-specific parameter of simplicia and ethanolic 70% extract of &lt;em&gt;D. hispida&lt;/em&gt; tubers from three different regions. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; The samples were macerated by using ethanol 70%. &lt;strong&gt;Results: &lt;/strong&gt;The results showed that the specific parameters of &lt;em&gt;D. hispida &lt;/em&gt;simplicia; the total water soluble extract was 11.25-16.20%; the total ethanol soluble extract was 6.42-9.39%; the chromatogram profile was obtained by using thin layer chromatography in toluene-ethyl acetate-chloroform (5:1:4) mobile phase with β–sitosterol as standard, the total phenolic content was 2.15–2.50 expressed in mgGAE/g simplicia. The non-specific parameters of &lt;em&gt;D. hispida &lt;/em&gt;simplicia; the total loss on drying was 10.53-12.40%; the total ash content was 5.81-5.94%; the total acid insoluble ash content was 0.20-0.22%. The specific parameters of &lt;em&gt;D. hispida&lt;/em&gt; extract; the total phenolic content was 10.30-11.72 expressed in mgGAE/g extract. The non-specific parameters of &lt;em&gt;D. hispida&lt;/em&gt; extract; the total water content was 10.27-10.47%; the total ash content was 2.84-2.93%; the total acid insoluble ash content was 0.14-0.19. &lt;strong&gt;Conclusion:&lt;/strong&gt; conform the parameters.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Research Study</style></work-type><section><style face="normal" font="default" size="100%">759</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sasmita Retno Sari, Berna Elya*, Katrin &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok 16424 West Java, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Aleksandr Vladimirovich Nikulin</style></author><author><style face="normal" font="default" size="100%">Olga Georgievna Potanina</style></author><author><style face="normal" font="default" size="100%">Evgeniy Alexandrovich Platonov</style></author><author><style face="normal" font="default" size="100%">Dmitry Olegovich Bokov</style></author><author><style face="normal" font="default" size="100%">Olga Aleksandrovna Smyslova</style></author><author><style face="normal" font="default" size="100%">Rimma Aleksandrovna Abramovich</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development and Validation of a Spectrophotometric Procedure for Determining Silicon in Common Horsetail (Equisetum arvense L.) Herb</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Equisetum arvense</style></keyword><keyword><style  face="normal" font="default" size="100%">Horsetail herb</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plant raw material</style></keyword><keyword><style  face="normal" font="default" size="100%">Silicon</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1124-1131</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;An accurate, simple and selective UV-spectrophotometric method was developed for the estimation of silicon in medicinal plant raw material – horsetail herb (&lt;em&gt;Equisetum arvense&lt;/em&gt; L.) of Russian origin.&lt;strong&gt; Methods:&lt;/strong&gt; The determination of total silicon content in terms of silicon dioxide (SiO&lt;sub&gt;2&lt;/sub&gt;) by the direct ultraviolet–visible (UV-Vis) spectrophotometry method (at a wavelength of 815 ± 5 nm) in the horsetail herb is based on the formation of yellow-colored silicomolybdic acid, and its further reduction to molybdenum blue. &lt;strong&gt;Results:&lt;/strong&gt; Recoveries were found to be in the range of 100.2 to 105.1% and %RSD was less than 2%. &lt;strong&gt;Conclusion:&lt;/strong&gt; The developed method is accurate, specific, precise within an interval 2-12% and suitable for the analysis of horsetail herb commercial samples.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><section><style face="normal" font="default" size="100%">1124</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Aleksandr Vladimirovich Nikulin&lt;sup&gt;1&lt;/sup&gt;, Olga Georgievna Potanina&lt;sup&gt;1&lt;/sup&gt;, Evgeniy Alexandrovich Platonov&lt;sup&gt;1&lt;/sup&gt;, Dmitry Olegovich Bokov&lt;sup&gt;2,3,&lt;/sup&gt;*, Olga Aleksandrovna Smyslova&lt;sup&gt;2&lt;/sup&gt;, Rimma Aleksandrovna Abramovich&lt;sup&gt;1 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Рeoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Street, Moscow, 117198, RUSSIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Institute of Pharmacy, Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, Moscow, 119991, RUSSIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;3&lt;/sup&gt;Laboratory of Food Chemistry, Federal Research Center for Nutrition, Biotechnology and Food Safety, 2/14 Ustyinsky pr., Moscow, 109240, RUSSIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Silvia Surini</style></author><author><style face="normal" font="default" size="100%">Antik R Arnedy</style></author><author><style face="normal" font="default" size="100%">Raditya Iswandana</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development of Ethosome Containing Bitter Melon (Momordica charantia Linn.) Fruit Fraction and In Vitro Skin Penetration</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bitter melon fruits</style></keyword><keyword><style  face="normal" font="default" size="100%">Charantin</style></keyword><keyword><style  face="normal" font="default" size="100%">Ethosomes</style></keyword><keyword><style  face="normal" font="default" size="100%">Skin penetration</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1242-1251</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; Bitter melon fruit, which is containing charantin, has poor penetration through the skin. This problem can be solved with the lipid vesicle called ethosomes that offers better skin penetration. This study was aimed to develop ethosomes for improving skin penetration ability of charantin. &lt;strong&gt;Methods:&lt;/strong&gt; Bitter melon was extracted with ethanol 80% and fractionated with dichloromethane. Ethosomes were formulated with a various concentration equal to 2% (F1), 3% (F2) and 4% (F3) of bitter melon fruits fraction (BMFF) and prepared using thin layer hydration method. The obtained ethosomes were characterized, then the penetration study was conducted using Franz diffusion cells. &lt;strong&gt;Results: &lt;/strong&gt;The results showed that the BMFF was a dry, brown-greenish fraction and gave a positive test for a steroid. The entrapment efficiency of ethosomes F1, F2 and F3 was 91.50 ± 0.40%, 92.62 ± 0.26% and 83.85 ± 1.10%, respectively. Moreover, the particle size (Dv90) of ethosomes F1, F2 and F3 was 1083.33 ± 15.27 nm, 1736.67 ± 11.55 nm and 1976.67 ± 5.77 nm, respectively. Ethosomes F1, F2 and F3 resulted polydispersity index of 0.42 ± 0.02, 0.35 ± 0.05 and 0.50 ± 0.11, as well as zeta potential of -54.33 ± 0.75, -57.50 ± 0.44 and -50.60 ± 0.98, respectively. Besides, all ethosomes had a spherical shape. The research revealed that ethosome F2 was the optimal ethosome among another formulas. Cumulative percentage of penetrated stigmasterol glycoside for ethosome F2 was 18.25 ± 0.08%, while the control solution did not penetrate within 20 h. &lt;strong&gt;Conclusion:&lt;/strong&gt; This research demonstrated that the ethosome could increase the skin penetration of stigmasterol glycoside, which is charantin content, from the fraction of bitter melon fruit.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1242</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Silvia Surini*, Antik R. Arnedy, Raditya Iswandana &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Laboratory of Pharmaceutics and Pharmaceutical Technology Development, Faculty of Pharmacy, Universitas Indonesia, Depok, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Muhajri Agusfina</style></author><author><style face="normal" font="default" size="100%">Fadlina Chany Saputri</style></author><author><style face="normal" font="default" size="100%">Aditya Sindu Sakti</style></author><author><style face="normal" font="default" size="100%">Abdul Mun’im</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Difference of Acidic Adding Effect in Ethanol Extraction of White Mulberry Stem Bark (Morus alba) and DPP-4 Inhibiting Activity Screening for Identifying its Antidiabetic Potential</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Apigenin</style></keyword><keyword><style  face="normal" font="default" size="100%">DPP IV</style></keyword><keyword><style  face="normal" font="default" size="100%">Morus alba</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">790-795</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; Murberry (&lt;em&gt;Morus alba&lt;/em&gt;) is one of the plants that can be used to treat diabetes and bioactive compounds that play a role are apigenin. Apigenin compounds have been reported to have an antidiabetic effect and are found in the form of glycosides. To separate apigenin from its glycosides, it takes the process of hydrolysis using acid. This study aims to look at the differences between ethanol extracts without hydrolysis with acids and ethanol extracts which are hydrolyzed by acid and determine their activity as dipeptidyl peptidase-4 (DPP-4) inhibitors&lt;em&gt; in vitro&lt;/em&gt;. &lt;strong&gt;Methods: &lt;/strong&gt;&lt;em&gt;Morus alba&lt;/em&gt; stem bark dry powder was extracted MAE using 96% ethanol with acid hydrolysis using HCl 2 N and extracted without acid hydrolysis then apigenin levels can be measured by each extraction process using HPLC. DPP-4 activity was evaluated using glycyl-prolyl-7-amino-4-methyl coumarin (Gly-Pro-AMC) substrate then the inhibitory effect of extracts was determined based on the number of free AMCs by measuring fluorescence at excitation wavelengths of 350-360 nm and emission wavelengths of 450-465 nm using micro-plate readers. Sitagliptin is used as a positive control of DPP-4 inhibition in this test. &lt;strong&gt;Results:&lt;/strong&gt; The ethanol extraction method with acid hydrolysis can attract more apigenin compounds than the ethanol extraction method without acid hydrolysis. The level of apigenin in the sample of ethanol extract with acid hydrolysis was 0.16%, and in the ethanol extract without acid hydrolysis was 0.04%. The amount of inhibitory activity of DPP-4 &lt;em&gt;Morus alba &lt;/em&gt;stem bark extract was 23%, which is 0.33 times the inhibition of sitagliptin activity. &lt;strong&gt;Conclusion: &lt;/strong&gt;Extraction methods with acid hydrolysis are more effective in attracting apigenin compounds than without acid hydrolysis. &lt;em&gt;Morus alba&lt;/em&gt; stem bark extract has an anti-diabetic effect through the mechanism of action of DPP-4 inhibitors can be used as a reference for therapy of diabetes mellitus from natural ingredients.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">790</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Muhajri Agusfina&lt;sup&gt;1&lt;/sup&gt;, Fadlina Chany Saputri&lt;sup&gt;3&lt;/sup&gt;, Aditya Sindu Sakti&lt;sup&gt;4&lt;/sup&gt;, Abdul Mun’im&lt;sup&gt;2,&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Graduate Programme of Herbal Medicine, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, West Java, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy- Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmacology-Toxicology, Faculty of Pharmacy, Universitas Indonesia, 16424, Depok, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Faculty of Pharmacy, Universitas Indonesia, 16424, Depok, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Theeraphan Chumroenphat</style></author><author><style face="normal" font="default" size="100%">Issaraporn Somboonwatthanakul</style></author><author><style face="normal" font="default" size="100%">Surapon Saensouk</style></author><author><style face="normal" font="default" size="100%">Sirithon Siriamornpun</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Diversity of Biologically Active Compounds in the Rhizomes of Recently Discovered Zingiberaceae Plants Native to North Eastern Thailand</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antiglycation</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidants</style></keyword><keyword><style  face="normal" font="default" size="100%">Bioactive compounds</style></keyword><keyword><style  face="normal" font="default" size="100%">Essential amino acids</style></keyword><keyword><style  face="normal" font="default" size="100%">Ginger family</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1014-1022</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To identify and quantify the bioactive compounds, along with biological activities, of native Thai edible Zingiberaceae. &lt;strong&gt;Methods: &lt;/strong&gt;The bioactive compounds evaluated were phenolic acids, flavonoid, vitamin C, curcumin, 6-gingerol, eugenol and essential amino acids; analyses involved HPLC and LCMS/MS. Antioxidant activities were assessed by DPPH and FRAP assays. &lt;strong&gt;Results:&lt;/strong&gt; &lt;em&gt;Zingiber officinale &lt;/em&gt;was the richest source of bioactive compounds, followed by&lt;em&gt; Z. officinale&lt;/em&gt;, &lt;em&gt;Alpinia zerumbet&lt;/em&gt; and&lt;em&gt; Alpinia conchigera&lt;/em&gt;. Total phenolic content and total flavonoid contents ranged widely across these species (17 to 200 mg GAE/100 g DW and 17 to 66 mg RE/100 g DW). All the species studied possessed strong antiglycation properties, ranging from 82 to 98%, with strong positive correlations of total phenolic content and antioxidant activity. The contents of curcumin, 6-gingerol, eugenol and vitamin C were in the range of 1 to 26, 1 to 140 μg/ g DW, 5 to 1600 and 4 to 21 mg/100 g DW, respectively. Seven essential amino acids identified by using LCMS/MS were found in most samples studied ranging from 2 to 6752 μg/100 g DW. &lt;strong&gt;Conclusion: &lt;/strong&gt;&lt;em&gt;Z. officinale&lt;/em&gt; is an abundant source of bioactive compounds and antioxidant activity in all these samples. These plants are fresh sources for developing novel functional ingredients in either food or cosmetics.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1014</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Theeraphan Chumroenphat&lt;sup&gt;1&lt;/sup&gt;, Issaraporn Somboonwatthanakul&lt;sup&gt;1&lt;/sup&gt;, Surapon Saensouk2, Sirithon Siriamornpun&lt;sup&gt;3&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biotechnology, Faculty of Technology, Mahasarakham University, Kantarawichai, Maha Sarakham 44150, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Plant and Invertebrate Taxonomy and Its Applications Unit Group, WalaiRukhavej Botanical Research Institute, Mahasarakham University, Kantarawichai District, Mahasarakham, 44150, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Research Unit of Process and Product Development of Functional Foods, Department of Food Technology and Nutrition, Faculty of Technology, Mahasarakham University, Kantarawichai, Maha Sarakham 44150, THAILAND.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mamillapalli Vani</style></author><author><style face="normal" font="default" size="100%">Shaik Abdul Rahaman</style></author><author><style face="normal" font="default" size="100%">Avula Prameela Rani</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Detection and Quantification of Major Phytochemical Markers for Standardization of Talinum Portulacifolium, Gomphrena Serrata, Alternanthera Sessilis and Euphorbia Heterophylla by HPLC</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Extracts.</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Kaempferol</style></keyword><keyword><style  face="normal" font="default" size="100%">Marker</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant specimens</style></keyword><keyword><style  face="normal" font="default" size="100%">Quality control</style></keyword><keyword><style  face="normal" font="default" size="100%">Quercetin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/505</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">439-446</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; High-performance liquid chromatography is one of the major analytical techniques used in the quality control of phytochemicals. &lt;strong&gt;Objective:&lt;/strong&gt; This research article presents the development of HPLC method to detect and quantify the major marker components, kaempferol, and quercetin from four plant species. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; HPLC method was developed for the qualitative and quantitative analysis of plant extracts by using orthophosphoric acid and methanol (95:5) at 370 nm for kaempferol, methanol and orthophosphoric acid (60:40) at 262nm for quercetin. &lt;strong&gt;Results:&lt;/strong&gt; Kaempferol was detected from the hydro alcoholic extracts of &lt;em&gt;Talinum portulacifolium&lt;/em&gt; leaves (RT 13.720, concentration 1.08 mg/ml) and flowers of &lt;em&gt;Gomphrena serrata&lt;/em&gt; (RT 13.758, concentration 2.13mg/ml). Kaempferol was reported for the first time from &lt;em&gt;Gomphrena serrata&lt;/em&gt;. Quercetin was separated and identified from the hydro alcoholic extracts &lt;em&gt;Alternanthera sessilis&lt;/em&gt; stems (RT 6.503, concentration 0.01mg/ml). The hydroalcoholic extract of &lt;em&gt;Euphorbia heterophylla&lt;/em&gt; stems (RT 6.588, concentration 0.01mg/ml) was also evaluated for the presence of quercetin. &lt;strong&gt;Conclusion:&lt;/strong&gt; The method developed is very useful tool for qualifying and quantifying the plant specimens as well as their extracts.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">439</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Mamillapalli Vani&lt;sup&gt;1*&lt;/sup&gt;, Shaik Abdul Rahaman&lt;sup&gt;2&lt;/sup&gt;, Avula Prameela Rani&lt;sup&gt;3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacy, Jawaharlal Nehru Technological University, Kakinada, East Godavari (Dt.), Andhra Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy and Phytochemistry, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Krishna, Andhra Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Medicinal Chemistry, Principal, Nirmala College of Pharmacy, Atmakur, Mangalagiri, Guntur, Andhra Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Pharmaceutics, University College of Pharmaceutical Sciences, Acharya Nagarjuna University, Nagarjunanagar, Guntur, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dharya Singh</style></author><author><style face="normal" font="default" size="100%">Vidhu Aeri</style></author><author><style face="normal" font="default" size="100%">DB Ananthanarayana</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development of Standard Operating Protocol for Slide Preparation of Powdered Bark Samples with Varying Grinding Techniques.</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacog Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Grinding technique</style></keyword><keyword><style  face="normal" font="default" size="100%">Powder microscopy</style></keyword><keyword><style  face="normal" font="default" size="100%">Slide optimization</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January-2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/477</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">265-271</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Powder microscopy is the most common method to authenticate herbal drugs. The botanical origin and quality can be determined based on cellular features. &lt;strong&gt;Objective:&lt;/strong&gt; To develop a standard operating protocol to prepare slides of powdered bark samples obtained by using different grinding techniques. &lt;strong&gt;Materials and methods:&lt;/strong&gt; &lt;em&gt;Alstonia scholaris, Saraca asoca, Syzygium cumini, Terminalia arjuna and Pongamia pinnata&lt;/em&gt; were selected for study. Three samples of each bark were studied: Sample A was collected from NISCAIR Pusa, New Delhi. Sample B and C were procured from industries and were coded as: AP I, AP II, AP III, AP IV and AP V and MP I, MP II, MP III, MP IV and MP V respectively. The slides were prepared by soaking and chemical treatment and photographed by Motic microscope. The samples were observed for general and specific features of the bark and the impact of grinding (industrial grinding and blade grinding in laboratory) on probability of change in various microscopical features. &lt;strong&gt;Results:&lt;/strong&gt; The microscopical features were found to be stable and specific, which can be used to determine the botanical identity of the drug. There was no significant difference in microscopical characters of powdered barks which emphasized that grinding technique does not have any impact on powder microscopy of different bark samples. The method of preparation of slide was also optimized. Conclusion: Powder microscopy, irrespective of grinding technique can be used as a cheap, fast, efficient and accurate method to authenticate herbs or distinguishing species with similar morphological characters without cutting and examining sections.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">265</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Dharya Singh, Vidhu Aeri*, DB Ananthanarayana. &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard,New Delhi-62, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Meiliza Ekayanti</style></author><author><style face="normal" font="default" size="100%">Rani Sauriasari</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Dipeptidyl peptidase IV Inhibitory Activity of Fraction from White Tea Ethanolic Extract (Camellia sinensis (L.) Kuntze) ex vivo</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antidiabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Camellia sinensis</style></keyword><keyword><style  face="normal" font="default" size="100%">Dipeptidyl peptidase IV</style></keyword><keyword><style  face="normal" font="default" size="100%">DPP IV</style></keyword><keyword><style  face="normal" font="default" size="100%">Fraction</style></keyword><keyword><style  face="normal" font="default" size="100%">White tea.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/418</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">190-193</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Treatment for type-2 diabetes mellitus focuses on the incretin hormone, Glucagon-Like Peptide-1 (GLP-1). However, it has a short half-life. Inhibition of the enzyme Dipeptidyl peptidase IV (DPP IV) required maintaining the active form of GLP-1. Based on the previous studies on the highest activity of DPP IV enzyme inhibition of white tea extract, this study conducted on the fraction of white tea extract using rat blood serum (&lt;em&gt;ex vivo&lt;/em&gt;). &lt;strong&gt;Objectives:&lt;/strong&gt; This study aims to evaluate the inhibitory activity of fraction from white tea extract. &lt;strong&gt;Methods:&lt;/strong&gt; White tea leaves extracted with ethanol. The inhibitory activity determined by using rat blood serum as DPP IV enzyme source (&lt;em&gt;ex vivo&lt;/em&gt;), AMC (7-amino 4-methyl coumarin) as fluorescence substrate of DPP IV and sitagliptin as the standard reference. The the cleavage of fluorescence reaction product observed by a microplate reader with &amp;lambda;&lt;sub&gt;ex&lt;/sub&gt; = 360 nm and &amp;lambda;&lt;sub&gt;em&lt;/sub&gt; = 460 nm at 37&lt;sup&gt;o&lt;/sup&gt;C. Data expressed as mean &amp;plusmn; SD and the IC&lt;sub&gt;50&lt;/sub&gt; value determined by nonlinear regression curve and fit using Prism Graph 7. &lt;strong&gt;Result:&lt;/strong&gt; Methanol fraction (250 &amp;mu;g/mL) has the greater inhibition percentage (50.487%), and the fraction of n-hexane and ethyl acetate are 32.417% and 36.541%. The methanol fraction IC&lt;sub&gt;50&lt;/sub&gt; value is 227 &amp;mu;g /mL. &lt;strong&gt;Conclusion:&lt;/strong&gt; The methanol fraction is the most active to inhibit DPP IV enzyme.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">190</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Meiliza&amp;nbsp;Ekayanti, Rani Sauriasari, Berna Elya*&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Faculty of Pharmacy, University of Indonesia, 16424, Depok, INDONESIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mariam Koleilat</style></author><author><style face="normal" font="default" size="100%">Karim Raafat</style></author><author><style face="normal" font="default" size="100%">Abdalla El-Lakany</style></author><author><style face="normal" font="default" size="100%">Maha Aboul-Ela</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Designing monographs for Rosmarinus officinalis L. and Lavandula angustifolia L.: Two Lebanese species with significant medicinal potentials</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Glandular trichome</style></keyword><keyword><style  face="normal" font="default" size="100%">Optical rotation</style></keyword><keyword><style  face="normal" font="default" size="100%">Prismatic crystals of Calcium oxalate</style></keyword><keyword><style  face="normal" font="default" size="100%">Refractive index</style></keyword><keyword><style  face="normal" font="default" size="100%">Rosmarinic acid</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">/files/PJ-9-4/10.5530pj.2017.4.75</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">452-474</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; The world health organization recommends validating medicinal plants to ensure safety and efficacy. Lavandula is valued for the production of essential oil used in aromatherapy. &lt;em&gt;Rosmarinus &lt;/em&gt;is known for its folk use as anti-oxidant and antidiabetic. This study aims to design monographs for &lt;em&gt;Rosmarinus officinalis&lt;/em&gt; (Linn.) and &lt;em&gt;Lavandula angustifolia&lt;/em&gt; (Linn.) cultivated, in conditions similar to their natural habitat, at Beirut Arab University botanical garden. Also screening the antioxidant activity of both plants, and assessing the antidiabetic effect of &lt;em&gt;R. officinalis&lt;/em&gt; (Linn.). &lt;strong&gt;Methods:&lt;/strong&gt; macroscopic and microscopic examination, hydrodistillation to obtain essential oils (EOs), thin layer chromatography, Gas chromatography-Mass spectrometry, and physiochemical properties of the EOs were determined. The antioxidant effect of the EOs is determined by DPPH assay. The antidiabetic effect of Rosemary EO is investigated using alloxan-induced diabetic mice. &lt;strong&gt;Results:&lt;/strong&gt; the qualities of studied species are in agreement with the standards described in WHO monographs and in the British pharmacopeia. Composition of the EO produced from either Rosemary (REO) or Lavender (LEO) collected at different months showed differences. The EO of both showed significant antioxidant effects in DPPH assay (p&amp;lt;0.05). &lt;em&gt;In vivo&lt;/em&gt; investigation of the antidiabetic effect of REO showed a significant antidiabetic effect in diabetic mouse model (p&amp;lt;0.05). &lt;strong&gt;Conclusion:&lt;/strong&gt; both plant species and their EOs fulfilled most of standards specified by the British Pharmacopeia 2013. Rosemary collected in April (Spring) showed the best antioxidant activity. Lavender collected in September (Early Fall) showed the best antioxidant activity. REO revealed significant lowering in blood glucose level at the dose of 110 mg/kg.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">452</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Mariam Koleilat, Karim Raafat*, Abdalla El-Lakany, Maha Aboul- Ela &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmaceutical Sciences, Faculty of Pharmacy, Beirut Arab University, 115020 Beirut, LEBANON.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vijay Vikram Singh</style></author><author><style face="normal" font="default" size="100%">Jainendra Jain</style></author><author><style face="normal" font="default" size="100%">Arun Kumar Mishra</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determination of Antipyretic and Antioxidant Activity of Cassia occidentalis Linn Methanolic Seed Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant.</style></keyword><keyword><style  face="normal" font="default" size="100%">Antipyretic</style></keyword><keyword><style  face="normal" font="default" size="100%">Cassia occidentalis L.</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacological</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytochemical</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/196</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">913-916</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; To perform the pharmacognostical screening and determination of antipyretic and antioxidant activity of &lt;em&gt;Cassia occidentalis&lt;/em&gt; L. Methanolic seed extract by different &lt;em&gt;in-vitro&lt;/em&gt; models. &lt;strong&gt;Methods:&lt;/strong&gt; The different pharmacognostical parameters were evaluated as per standard procedure. Finally, antipyretic (Brewer&amp;rsquo;s Yeast Pyrexia model) and antioxidant activity (DPPH and Hydrogen Pyrode Method) was evaluated by adopting different methods. &lt;strong&gt;Results:&lt;/strong&gt; The extracts showed a marked antipyretic effect (Figure 1) by causing a reduction in yeast-induced fever. Methanolic extract (400 mg/kg) showed the effect to the same degree as paracetamol (20 mg/kg, i.p.). The experimentally induced laboratory model was employed in evaluating the antipyretic activities of methanolic extracts of &lt;em&gt;Cassia occidentalis&lt;/em&gt; L. The extract caused a better hypothermal activity against yeast-induced pyrexia in rats. Free radical scavenging activity of &lt;em&gt;Cassia occidentalis&lt;/em&gt; L. was found because polyphenolic compounds present in plant contribute significantly to the total antioxidant capacity of the seed. Flavonoids play some important pharmacological roles against diseases, such as cardiovascular diseases, cancer, inflammation and allergy. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results of the study indicate that the methanolic seed extract of &lt;em&gt;Cassia occidentalis&lt;/em&gt; L. possesses strong antipyretic and antioxidant activity. This study described many pharmacognostical features and antioxidant activity of seeds of &lt;em&gt;Cassia occidentalis&lt;/em&gt; L. which will give a new direction for the future scientific research.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">913</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Vijay Vikram Singh&lt;sup&gt;1*&lt;/sup&gt;, Jainendra Jain&lt;sup&gt;1&lt;/sup&gt;, Arun Kumar Mishra&lt;sup&gt;2&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacy, Ram-Eesh Institute of Vocational and Technical Education, Greater Noida (U.P.) INDIA.&lt;/p&gt;
&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Phytochemistry Laboratory, School of Pharmaceutical Sciences, IFTM University, Moradabad (U.P) INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dachriyanus</style></author><author><style face="normal" font="default" size="100%">Nova Susanti Asjar</style></author><author><style face="normal" font="default" size="100%">Meri Susanti</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determination of Rubraxanthone in the Latex of Asam Kandis (Garcinia cowa Roxb) by Reverse Phase High Performance Liquid Chromatography.</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Counterfeiting</style></keyword><keyword><style  face="normal" font="default" size="100%">Isocratic method</style></keyword><keyword><style  face="normal" font="default" size="100%">Latex of Garcinia cowa Roxb</style></keyword><keyword><style  face="normal" font="default" size="100%">RP-HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">rubraxanthone</style></keyword><keyword><style  face="normal" font="default" size="100%">Standarization</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://phcogj.com/fulltext/317</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">288-291</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Context:&lt;/strong&gt; Rubraxanthone is a major compound found in &lt;em&gt;Garcinia cowa&lt;/em&gt; Roxb which has various biological activities. This compound is likely to be responsible for the pharmacological activities of this plant. The latex of this plant was one of the source of this compound. To prevent counterfeiting, it is essential to develop a method of analysis to determine the levels of these compounds in the latex of &lt;em&gt;G. cowa&lt;/em&gt;. &lt;strong&gt;Aims:&lt;/strong&gt; To develop and validated a reverse phase-high performance liquid chromatography (RP-HPLC) technique for determination of rubraxanthone in the latex of &lt;em&gt;G. cowa&lt;/em&gt;. &lt;strong&gt;Settings and Design:&lt;/strong&gt; RP-HPLC analysis. &lt;strong&gt;Methods and Material:&lt;/strong&gt; The sample was powdered and dissolve in methanol and then subjected to Reverse Phase High Performace Liquid Chromatoraphy (RP-HPLC). Separation was carried out in a reversed-phase column Shimadzu Shimp-pack VP&amp;ndash;ODS (4.6 x 250 mm). The elution was performed with isocratic solvent using formic acid 0.4 % v/v in methanol (15:85) with a flow rate 1 ml/minute. The solvents used for the mobile phase were filtered through membrane filter (0.45 mm pore size) and degassed before use. Total running time was 20 minutes and the sample injection volume of injection was 20 ml. While the wavelength of the UV-VIS detector was set at 243.2 nm. &lt;strong&gt;Results:&lt;/strong&gt; The detection and the quantitation limits of rubraxanthone were 1.119 mg/mL and 3.731 &amp;mu;g/mL, respectively. A regression analysis was performed, with the observation of good linearity (r = 0.998). The values obtained for precision and accuracy determination are in agreement with ICH guidelines. It was found that rubraxanthone in dichloromethane extract of latex &lt;em&gt;G. cowa&lt;/em&gt; was 56.56%. &lt;strong&gt;Conclusions:&lt;/strong&gt; The results demonstrated that the developed method is a reliable HPLC technique for determination of rubraxanthone in the latex of &lt;em&gt;G. cowa&lt;/em&gt;.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">288</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Dachriyanus*, Nova Susanti Asjar, Meri Susanti &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Andalas University, Kampus Limau Manis, Padang, West Sumatra, Indonesia.&amp;nbsp;&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mukund Manikrao Donglikar</style></author><author><style face="normal" font="default" size="100%">Sharada Laxman Deore</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development and Evaluation of Herbal Sunscreen</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Curcumin</style></keyword><keyword><style  face="normal" font="default" size="100%">Quercetin</style></keyword><keyword><style  face="normal" font="default" size="100%">Resveratrol</style></keyword><keyword><style  face="normal" font="default" size="100%">safranal</style></keyword><keyword><style  face="normal" font="default" size="100%">SPF.</style></keyword><keyword><style  face="normal" font="default" size="100%">Sunscreen</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">83-97</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;Thus present research work deals with the development and evaluation of topical photo protective formulation, containing antioxidant, wound healing, anti-inflammatory and rather photo protective poly phenols like curcumin, quercetin, resveratrol and safranal. The present research work provides stable natural photo protective formulation with antioxidant potential, high SPF and more important uniform UVA/UVB protection.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">83</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Mukund Manikrao Donglikar&lt;sup&gt;1&lt;/sup&gt; and Sharada Laxman Deore&lt;sup&gt;2*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Sciences, Shri Jagdish Prasad Jhabarmal Tibrewala University, Vidyanagari, Jhunjhunu, Rajasthan-333001, INDIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy and Phytochemistry, Government College of Pharmacy, Amravati-444604, Maharashtra, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Venkata Siva Satyanarayana Kantamreddi</style></author><author><style face="normal" font="default" size="100%">V. Thirumala Veni</style></author><author><style face="normal" font="default" size="100%">Murali Krishna Malasani</style></author><author><style face="normal" font="default" size="100%">Boddana Simhachalam</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Differentiation of Five Commercially Available Triphala churnas of an Ayurvedic Formulation by Elemental Fingerprint</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ayurvedic Drugs</style></keyword><keyword><style  face="normal" font="default" size="100%">Elemental Fingerprint</style></keyword><keyword><style  face="normal" font="default" size="100%">Fuzzy c-Means</style></keyword><keyword><style  face="normal" font="default" size="100%">Hierarchical Cluster Analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Inductively Coupled Plasma Mass Spectrometry</style></keyword><keyword><style  face="normal" font="default" size="100%">k-Means</style></keyword><keyword><style  face="normal" font="default" size="100%">Triphala churna</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">117-122.</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt;&lt;em&gt;Triphala churna&lt;/em&gt;&lt;/span&gt; (TPC) is one of the well known &lt;em&gt;Ayurvedic&lt;/em&gt; powdered preparations of Indian System of Medicine and is used in the treatment of various diseases. Elemental pattern of TPC was developed in order to investigate the identity and quality of commercial TPC drugs. &lt;strong&gt;Method:&lt;/strong&gt; Inductively coupled plasma mass spectrometry (ICP-MS) was used for the quantitative determination of ten essential and trace elements in five marketed samples of &lt;em&gt;Triphala churna&lt;/em&gt;. The concentration patterns of these elements were deciphered by multivariate statistical analysis such as hierarchical cluster analysis (HCA), fuzzy c-means (FCM) and k-means (KM) cluster analysis. &lt;strong&gt;Results:&lt;/strong&gt; The elemental concentrations ranged from 1.3 mg/kg (Cr, TPC3) to 14220 mg/kg (K, TPC4). The elemental fingerprint of &lt;em&gt;Triphala churna&lt;/em&gt; was established based on three churnas viz. TPC1, TPC3 and TPC5, which were found in one cluster with a very high degree of similarity by KM, FCM and HCA techniques. &lt;strong&gt;Conclusion:&lt;/strong&gt; Based on the results, the graphical pattern of elements detected in these samples can be considered as elemental fingerprint of &lt;em&gt;Triphala churna&lt;/em&gt; and can be used for authentication and/or to determine the quality of commercial TPC drugs.&amp;nbsp;&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">117</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Venkata Siva Satyanarayana Kantamreddi&lt;sup&gt;1&lt;/sup&gt;&lt;sup&gt;,2&lt;/sup&gt;*, Thirumala Veni Vasupalli&lt;sup&gt;1&lt;/sup&gt;, Murali Krishna Malasani&lt;sup&gt;2&lt;/sup&gt;, and Simhachalam Boddana&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Centre for Chemical Analysis, Central Research Laboratory, GIT, GITAM University, Visakhapatnam, INDIA&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;S.V. Enviro Labs &amp; Consultants, IDA, Auto Nagar, Visakhapatnam, INDIA&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Mathematics, GIT, GITAM University, Visakhapatnam, INDIA&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Temin Payum</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Distribution, Ethnobotany, Pharmacognosy and Phytoconstituents of Coptis teeta Wall.: A Highly Valued and Threatened Medicinal Plant of Eastern Himalayas</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Berberine</style></keyword><keyword><style  face="normal" font="default" size="100%">Eastern Himalayas</style></keyword><keyword><style  face="normal" font="default" size="100%">Medicinal plant</style></keyword><keyword><style  face="normal" font="default" size="100%">Mishmi tribe</style></keyword><keyword><style  face="normal" font="default" size="100%">Phytoconstituents</style></keyword><keyword><style  face="normal" font="default" size="100%">Threatened</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/378</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">s28-s34</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objectives:&amp;nbsp;&lt;/strong&gt;To study the distribution, traditional knowledge, dose and preparations, phytoconstituents, pharmacognostic characters and to correlate phytoconstituents and the claimed health benefits among the tribal people of Arunachal Pradesh if any, the present study was carried out. &lt;strong&gt;Methods:&lt;/strong&gt; Field survey and interview were used for ethnobotany and protocol given in Shah and Seth (2010), Kakote &lt;em&gt;et. al.&lt;/em&gt;,(2012) and Wallis (2011) was followed to study pharmacognostic studies while GC-MS was used in the studies of phytoconstituents. &lt;strong&gt;Results:&lt;/strong&gt; This study reports numbers of volatile and non-volatile compounds from the rhizome of &lt;em&gt;Coptis teeta&lt;/em&gt; with high percentage of berberine alkaloids. The study also reports alkaloid deposition at parenchymatous tissues and vascular tissues of rhizome. Phytoconstituents presents in the ethanolic extract of &lt;em&gt;C.teeta &lt;/em&gt;cold be related to health problems and phytoconstituents as claimed by tribal people of Arunachal Pradesh. &lt;strong&gt;Conclusion:&lt;/strong&gt; Locally called Mishmi teeta in Arunachal Pradesh, &lt;em&gt;Coptis teeta&lt;/em&gt; Wall. is a well-known medicinal plant used among Mishmi and other tribes of Arunachal Pradesh for health problems like loose motion, stomach pain, diarrhoea and malaria. This endemic and threatened medicinal plant contains numbers of biologically active compounds and need &lt;em&gt;in-situ&lt;/em&gt; as well as &lt;em&gt;ex-situ&lt;/em&gt; conservation.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s28</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Temin Payum &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Botany, J.N. College, Pasighat, Arunachal Pradesh-791103, INDIA.&amp;nbsp;&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sonam Sharma</style></author><author><style face="normal" font="default" size="100%">Siva Hemalatha</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">DNA Fingerprinting Profile and Quality Control Standardization of Folklore Medicinal Plant Exacum lawii</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">DNA fingerprinting</style></keyword><keyword><style  face="normal" font="default" size="100%">Exacum lawii</style></keyword><keyword><style  face="normal" font="default" size="100%">GC-MS.</style></keyword><keyword><style  face="normal" font="default" size="100%">Swertiamerin</style></keyword><keyword><style  face="normal" font="default" size="100%">Ursolic acid</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/175</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">775-785</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Context and Aim:&lt;/strong&gt; &lt;em&gt;Exacum lawii &lt;/em&gt;(Gentianaceae) is bitter folk medicinal herb. The study deals with molecular investigation by DNA fingerprinting profile of &lt;em&gt;Exacum lawii&lt;/em&gt;, quality control and phytochemical standardization of &lt;em&gt;Exacum lawii&lt;/em&gt;. &lt;strong&gt;Methods:&lt;/strong&gt; The DNA fingerprinting profile was performed by RAPD technique using 3 pairs of primers. The quality control standardization was done as per the WHO guidelines and official methods of AOAC. Phytochemical standardization employed quantitative estimations of phytoconstituents by spectrophotometric and identification using GCMS technique. The quantification of Swertiamerin and Ursolic acid in &lt;em&gt;Exacum lawii&lt;/em&gt; was carried by HPLC. &lt;strong&gt;Results:&lt;/strong&gt; Macroscopical and microscopical examination confirmed the diagnostic morphological and histological features. The content of vitamins, minerals and fatty acids were estimated. Physicochemical parameters obtained within the provided limits as per WHO. The phytochemical screening of ethanolic extract and its fraction revealed the presence of alkaloids, flavonoids, phenols, tannins, terpenoids, glycosides and steroids Total phenolics (57.4mg/g tannic acid equivalent), total tannins (15.3 mg/gm), total flavonoids (51.4 mg/gm rutin equivalent), total flavonols (5.4 mg/gm) and carbohydrates (12.6 mg/gm D-fructose equivalent) content were estimated using spectroscopic techniques. The GC-MS data revealed 20 compounds. Swertiamerin and Ursolic acid content was 119.59 mg/gm and 5.34 mg/gm respectively. &lt;strong&gt;Conclusion:&lt;/strong&gt; Present study provides the referential information to develop a monograph for quality control standardization of &lt;em&gt;Exacum lawii&lt;/em&gt;.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt; &lt;em&gt;Exacum lawii&lt;/em&gt;, DNA fingerprinting, Swertiamerin, Ursolic acid, GC-MS.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">775</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sonam Sharma, Siva Hemalatha&lt;sup&gt;*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmaceutics, Indian Institute of Technology, Banaras Hindu University, Varanasi-221005, Uttar Pradesh, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ian Edwin Cock</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Duboisia leichhardtii (F.Muell.) Extracts Inhibit The Growth of Bacterial Triggers of Selected Autoimmune Inflammatory Diseases</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">ankylosing spondylitis</style></keyword><keyword><style  face="normal" font="default" size="100%">Corkwood</style></keyword><keyword><style  face="normal" font="default" size="100%">Hyoscyamine.</style></keyword><keyword><style  face="normal" font="default" size="100%">multiple sclerosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Rheumatic Heart Disease</style></keyword><keyword><style  face="normal" font="default" size="100%">rheumatoid arthritis</style></keyword><keyword><style  face="normal" font="default" size="100%">Scopolamine</style></keyword><keyword><style  face="normal" font="default" size="100%">Solanaceae</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">542-550</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Duboisia leichhardtii &lt;/em&gt;F.Muell. is a medium to large tree which is native to subtropical regions of eastern Australia.&lt;em&gt; Duboisia&lt;/em&gt; spp. contain a number of psychoactive tropane and pyrrolidine alkaloids with reported antibacterial activity. Despite this, &lt;em&gt;D. leichhardtii&lt;/em&gt; leaf extracts have not been rigorously examined for growth inhibitory properties against many bacteria, including the bacterial triggers of autoimmune inflammatory diseases. &lt;strong&gt;Methods:&lt;/strong&gt; The antimicrobial activity of &lt;em&gt;D. leichhardtii&lt;/em&gt; leaf solvent extracts was investigated by disc diffusion and growth time course assays against a panel of bacterial triggers of autoimmune diseases. The growth inhibitory activity was further quantified by MIC determination and growth time course assays. Toxicity was determined using the &lt;em&gt;Artemia franciscana&lt;/em&gt; nauplii bioassay. &lt;strong&gt;Results: &lt;/strong&gt;Methanolic and aqueous &lt;em&gt;D. leichhardtii &lt;/em&gt;leaf solvent extracts were potent inhibitors of the bacterial triggers of rheumatoid arthritis and ankylosing spondylitis. The methanolic extract displayed the most potent bacterial growth inhibitory activity. It was particularly potent against &lt;em&gt;P. mirabilis &lt;/em&gt;(MICs of 85 and 116 &lt;em&gt;&amp;mu;&lt;/em&gt;g/mL against reference and clinical strains respectively) and &lt;em&gt;P. vulgaris&lt;/em&gt; (MIC of 187 &lt;em&gt;&amp;mu;&lt;/em&gt;g/mL). The methanolic extract was also a good inhibitor of &lt;em&gt;K. pneumoniae&lt;/em&gt; growth (MICs of 143 and 118 &lt;em&gt;&amp;mu;&lt;/em&gt;g/mL against reference and clinical strains respectively). The aqueous and ethyl acetate extracts were also potent bacterial growth inhibitors, albeit with higher MIC values. The antibacterial activity of the methanolic and aqueous &lt;em&gt;D. leichhardtii &lt;/em&gt;leaf extracts were further investigated by growth time course assays which showed significant growth inhibition in cultures of &lt;em&gt;P. mirabilis&lt;/em&gt; and &lt;em&gt;K. pneumoniae &lt;/em&gt;within 1 h of exposure. All extracts were determined to be nontoxic in the &lt;em&gt;Artemia franciscana &lt;/em&gt;nauplii bioassay, indicating their safety for use in preventing these autoimmune inflammatory diseases. &lt;strong&gt;Conclusions:&lt;/strong&gt; The lack of toxicity of the &lt;em&gt;D. leichhardtii&lt;/em&gt; leaf extracts and their growth inhibitory bioactivity against the bacterial triggers of rheumatoid arthritis and ankylosing spondylitis indicate their potential in the development of new therapies targeting the onset of these diseases.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">542</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ian Edwin Cock &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of Natural Sciences, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland 4111, AUSTRALIA.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Environmental Futures Research Institute, Griffith University, 170 Kessels Rd, Nathan, Brisbane, Queensland 4111, Australia.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yi-ming Li</style></author><author><style face="normal" font="default" size="100%">Yan-Ru Liu</style></author><author><style face="normal" font="default" size="100%">Bing-Kun Xiao</style></author><author><style face="normal" font="default" size="100%">Jian-Yun Yang</style></author><author><style face="normal" font="default" size="100%">Rong-Qing Huang</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Dynamic Comparison of Free Radical Scavenging Abilities of Hypericum Perforatum L., Herba Verbenae Officinalis, and Valeriana Officinalis L. Extracts</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">ABTS•+</style></keyword><keyword><style  face="normal" font="default" size="100%">DPPH•</style></keyword><keyword><style  face="normal" font="default" size="100%">Herba Verbena Officinalis</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypericum perforatum L.</style></keyword><keyword><style  face="normal" font="default" size="100%">Menopause Oxidative Stress</style></keyword><keyword><style  face="normal" font="default" size="100%">Valeriana officinalis L.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">09th Mar, 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">198-204</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objectives:&lt;/strong&gt; The purpose of this research was to compare the dynamic antioxidant activities and the free radical scavenging abilities of three botanical supplements, &lt;em&gt;Hypericum perforatum L&lt;/em&gt;. (HPL),&lt;em&gt; Herba Verbena Officinalis &lt;/em&gt;(HVO), and &lt;em&gt;Valeriana officinalis L. &lt;/em&gt;(VO), which have been reported to effectively treat menopause symptoms. &lt;strong&gt;Methods:&lt;/strong&gt; The antioxidant activities of the three supplements were determined by the ferric reducing ability of plasma (FRAP) assay. In addition, their free radical scavenging abilities were studied by ftheir interactions with the stable radicals of 2, 2&amp;rsquo;-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH). &lt;strong&gt;Results: &lt;/strong&gt;The results indicated that the HPL ethanolic extract exhibited greater antioxidant activity (1.2688 &amp;plusmn; 0.01 mmol Trolox/g) than the HVO ethanolic extract (1.1686&amp;plusmn; 0.043 mmol Trolox/g) and the VO ethanolic extract (0.2579 &amp;plusmn; 0.0031 mmol Trolox/g) as compared to Nilestriol (0.0026&amp;plusmn;0.0012), a positive control agent in the experiment. Moreover, the HPL extract showed remarkable free radical scavenging activity against ABTS&lt;strong&gt;&amp;bull;&lt;/strong&gt;+, and the HVO extract was the most potent against DPPH&lt;strong&gt;&amp;bull;&lt;/strong&gt;. &lt;strong&gt;Conclusion:&lt;/strong&gt; These activities may be attributed to the total flavonoid or phenolic acid contents of among these extracts.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words: &lt;/strong&gt;ABTS&amp;bull;+, DPPH&amp;bull;,&lt;em&gt; Hypericum perforatum L.,&lt;/em&gt;&lt;em&gt;Herba Verbena Officinalis&lt;/em&gt;, Menopause Oxidative Stress, &lt;em&gt;Valeriana officinalis L.&lt;/em&gt;&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">198</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Yi-ming Li&lt;sup&gt;1&lt;/sup&gt;,Yan-Ru Liu&lt;sup&gt;2,3&lt;/sup&gt;, Bing-Kun Xiao&lt;sup&gt;2&lt;/sup&gt;, Jian-Yun Yang&lt;sup&gt;2&lt;/sup&gt;, Rong-Qing Huang&lt;sup&gt;2* &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Anhui Medical University,Hefei 230032, P. R.China;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Beijing Institute of Radiation Medicine, Haidian District, Beijing 100850, P.R. China;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;The School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenhe District, Shenyang 110016, P.R. China&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yi-ming Li</style></author><author><style face="normal" font="default" size="100%">Yan-Ru Liu</style></author><author><style face="normal" font="default" size="100%">Bing-Kun Xiao</style></author><author><style face="normal" font="default" size="100%">Jian-Yun Yang</style></author><author><style face="normal" font="default" size="100%">Rong-Qing Huang</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Dynamic Comparison of Free Radical Scavenging Abilities of Hypericum Perforatum L., Herba Verbenae Officinalis, and Valeriana Officinalis L. Extracts</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">ABTS•+</style></keyword><keyword><style  face="normal" font="default" size="100%">DPPH•</style></keyword><keyword><style  face="normal" font="default" size="100%">Herba Verbena Officinalis</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypericum perforatum L.</style></keyword><keyword><style  face="normal" font="default" size="100%">Menopause Oxidative Stress</style></keyword><keyword><style  face="normal" font="default" size="100%">Valeriana officinalis L.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">01/2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">198-204</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objectives:&lt;/strong&gt; The purpose of this research was to compare the dynamic antioxidant activities and the free radical scavenging abilities of three botanical supplements, &lt;em&gt;Hypericum perforatum&lt;/em&gt; L. (HPL), &lt;em&gt;Herba Verbena Officinalis&lt;/em&gt; (HVO), and &lt;em&gt;Valeriana officinalis&lt;/em&gt; L. (VO), which have been reported to effectively treat menopause symptoms. &lt;strong&gt;Methods:&lt;/strong&gt; The antioxidant activities of the three supplements were determined by the ferric reducing ability of plasma (FRAP) assay. In addition, their free radical scavenging abilities were studied by ftheir interactions with the stable radicals of 2, 2&amp;rsquo;-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH). &lt;strong&gt;Results:&lt;/strong&gt; The results indicated that the HPL ethanolic extract exhibited greater antioxidant activity (1.2688 &amp;plusmn; 0.01 mmol Trolox/g) than the HVO ethanolic extract (1.1686&amp;plusmn; 0.043 mmol Trolox/g) and the VO ethanolic extract (0.2579 &amp;plusmn; 0.0031 mmol Trolox/g) as compared to Nilestriol (0.0026&amp;plusmn;0.0012), a positive control agent in the experiment. Moreover, the HPL extract showed remarkable free radical scavenging activity against ABTS&lt;strong&gt;&amp;bull;&lt;/strong&gt;+, and the HVO extract was the most potent against DPPH&lt;strong&gt;&amp;bull;&lt;/strong&gt;. &lt;strong&gt;Conclusion:&lt;/strong&gt; These activities may be attributed to the total flavonoid or phenolic acid contents of among these extracts.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">198</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Yi-ming Li&lt;sup&gt;1&lt;/sup&gt;, Yan-Ru Liu&lt;sup&gt;2,3&lt;/sup&gt;, Bing-Kun Xiao&lt;sup&gt;2&lt;/sup&gt;, Jian-Yun Yang&lt;sup&gt;2&lt;/sup&gt;, Rong-Qing Huang&lt;sup&gt;2*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Anhui Medical University,Hefei 230032, P. R.China.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Beijing Institute of Radiation Medicine, Haidian District, Beijing 100850, P.R. China.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;The School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenhe District, Shenyang 110016, P.R. China.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sharada L. Deore</style></author><author><style face="normal" font="default" size="100%">Sharad Chaudhari</style></author><author><style face="normal" font="default" size="100%">Bhushan A. Baviskar</style></author><author><style face="normal" font="default" size="100%">Somshekhar S. Khadabadi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development and Antifungal Evaluation of Cinnamaldehyde Containing Silver Nanoparticles against Candida albicans</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Letter to the Editor</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2nd July 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">63-65</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p &gt;NA&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Letter To The Editor</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sharada L. Deore&lt;sup&gt;1*&lt;/sup&gt;, Sharad Chaudhari&lt;sup&gt;1&lt;/sup&gt;, Bhushan A. Baviskar&lt;sup&gt;1&lt;/sup&gt;, Somshekhar S. Khadabadi&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;2 &lt;/strong&gt;&lt;/sup&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy and Phytochemistry, Government College of Pharmacy, Amravati, Maharashtra, India,&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy and Phytochemistry, Government College of Pharmacy, Aurangabad, Maharashtra, India.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ananth Kumar Kammalla,</style></author><author><style face="normal" font="default" size="100%">Mohan Kumar Ramasamy,</style></author><author><style face="normal" font="default" size="100%">Agarwal Aruna,</style></author><author><style face="normal" font="default" size="100%">Dubey GP,</style></author><author><style face="normal" font="default" size="100%">Ilango Kaliappan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development and validation of a RP-HPLC method for the simultaneous determination of Mangiferin, Ellagic acid and Hydroxycitric acid in polyherbal formulation</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ellagic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydroxycitric acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Mangiferin</style></keyword><keyword><style  face="normal" font="default" size="100%">Polyherbal formulation</style></keyword><keyword><style  face="normal" font="default" size="100%">RP-HPLC</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">8th April 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">23-28</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;The US patented polyherbal formulation for the prevention and management of Type II diabetes and its vascular complications was used for the present study. The formulation consists of roots of &lt;em&gt;Salacia species&lt;/em&gt;, leaves of &lt;em&gt;Lagestroemia parviflora&lt;/em&gt; and fruit rind of &lt;em&gt;Garcinia indica&lt;/em&gt;. The use of reversed phase C&lt;sub&gt;18&lt;/sub&gt; HPLC column was used and eluted with isocratic mobile phase of acetonitrile and phosphoric acid buffer solution enabled the efficient separation of chemical markers within 20min. Validation of the method was performed in order to demonstrate its selectivity, accuracy, precision, repeatability and recovery. All calibration curve shows good linear correlation coefficients (r&lt;sup&gt;2&lt;/sup&gt;&amp;gt;0.995) within tested ranges. Three markers in this polyherbal formulation were quantified were Mangiferin (1.53% w/w), Ellagic acid (0.9655 w/w), Hydroxycitric acid (5.3% w/w). Intra and inter day RSDs of retention times and peak areas were less than 3%. The recoveries were between 95% and 102.5%. In conclusion a method has been developed for the simultaneous quantification of three markers in this polyherbal formulation. The established RP-HPLC method was simple, precise and accurate and can be used for the quality control of the raw materials as well as formulations.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt; Polyherbal formulation, Mangiferin, Ellagic acid, Hydroxycitric acid, RP-HPLC.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ananth Kumar Kammalla&lt;sup&gt;1&lt;/sup&gt;, Mohan Kumar Ramasamy&lt;sup&gt;1&lt;/sup&gt;, Agarwal Aruna&lt;sup&gt;2&lt;/sup&gt;, Dubey GP&lt;sup&gt;3&lt;/sup&gt; and Ilango Kaliappan&lt;sup&gt;1*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Interdisciplinary School of Indian System of Medicine, SRM University, Kattankulathur-603203, Tamil Nadu, India&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;National Facility for Tribal &amp;amp; Herbal Medicine, Institute of Medical sciences, Banaras Hindu University, Varanasi, India&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Faculty of Ayurveda, Institute of Medical sciences, Banaras Hindu University, Varanasi, India.&lt;/p&gt;</style></auth-address></record></records></xml>