<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sahmad S</style></author><author><style face="normal" font="default" size="100%">Andi Zulkifli Abdullah</style></author><author><style face="normal" font="default" size="100%">Muh. Syafar</style></author><author><style face="normal" font="default" size="100%">Indahwaty Sidin</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Health Action Process Approach in Non-Communicable Diseases: A Systematic Review</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Behaviour change</style></keyword><keyword><style  face="normal" font="default" size="100%">Health action process approach</style></keyword><keyword><style  face="normal" font="default" size="100%">non-communicable diseases</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">107-116</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Epidemiological research has indicated that the deleterious effects of non-communicable disease can be prevented through participation in health behaviour. The HAPA is a dual-phase model that identifies the determinants of the initiation and maintenance of health behaviour. The aim of this study was to systematically map the Health Action Process Approach (HAPA)- based interventions in non-communicable diseases in relation to the type of intervention, the target groups and the constructs of the HAPA model that are used in the study and to assess the clinical relevance of the studies. &lt;strong&gt;Methods: &lt;/strong&gt;This review study complies with the Preferred Reporting Items for Systematic review and Meta-analysis (PRISMA) version 2020. The search for relevant literature involved PubMed, Sciencedirect, Willey online Library and Proquest databases for the studies published in 2000 to 2023 period. Quality of the study was assessed using CASP, and the Risk of Bias using Cochrane RoB tool.&lt;strong&gt; Results:&lt;/strong&gt; In data bases search, there are 912 studies. The results for eligibility resulted in 18 articles consist of 13 observational studies, and 5 experimental studies. &lt;strong&gt;Discussion: &lt;/strong&gt;Physical activity, healthy diet behaviour, and medication adherence were the targeted behaviour. In the majority of the studies, the targeted intervention was physical activity and the population consisted of adult patients. &lt;strong&gt;Conclusion:&lt;/strong&gt; All studies used only a selection of the HAPA constructs. Therefore, only a minority of the studies can be considered real HAPA intervention studies.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">107</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sahmad&lt;sup&gt;1*&lt;/sup&gt;, Andi Zulkifli Abdullah&lt;sup&gt;2&lt;/sup&gt;, Muh. Syafar&lt;sup&gt;3&lt;/sup&gt;, Indahwaty Sidin&lt;sup&gt;4&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;5&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Phd student, College of public health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Professor, Department of Epidemiology, College of public health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Professor, Department of Health behavioral science, College of public health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Associate Professor, Department of Hospital Management, College of public health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Professor, Department of Environmental Health Faculty of public health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Desi Novianti</style></author><author><style face="normal" font="default" size="100%">I Nyoman Ehrich Lister</style></author><author><style face="normal" font="default" size="100%">Ali Napiah Nasution</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective Potential of Coffea arabica Extract Against Carbon Tetrachloride Induced Liver Damage: Ultrasonographic and Cytokine Evaluation</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">CCl₄</style></keyword><keyword><style  face="normal" font="default" size="100%">Coffea arabica</style></keyword><keyword><style  face="normal" font="default" size="100%">Cytokines</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">liver protection</style></keyword><keyword><style  face="normal" font="default" size="100%">Ultrasonographic</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">742-750</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Carbon tetrachloride (CCl₄) is a hepatotoxic agent widely used to model liver injury in experimental animals, and coffee (&lt;em&gt;Coffea arabica&lt;/em&gt;) extract is known to contain various bioactive compounds with antioxidant and anti-inflammatory potential. This study aimed to evaluate the hepatoprotective activity of &lt;em&gt;Coffea arabica&lt;/em&gt; extract in male Wistar rats induced with CCl₄ through phytochemical analysis, liver biochemical parameters (albumin, bilirubin, SGOT, SGPT), inflammatory cytokines (TNF-α, IL-6, CRP), and liver morphology observations using ultrasonography and histopathology. The extract contained alkaloids, flavonoids, triterpenoids, saponins, and glycosides, with total phenolic and flavonoid contents of 51.32 mg GAE/g and 1.25 mg QE/g extract, respectively, and moderate antioxidant activity (IC₅₀ = 124.36 ppm). Administration of the extract at 300 mg/kg BW significantly improved liver structure, reduced TNF-α (120.62 ± 21.78 pg/mL), IL-6 (68 ± 14.44 pg/mL), CRP (199.0 ± 41.5 pg/mL), SGOT (147.0 ± 34.28 g/dL), and SGPT (69.6 ± 9.94 g/dL) levels, while increasing albumin (2.94 ± 0.34 g/dL) and reducing bilirubin (0.09 ± 0.04 mg/dL), approaching normal conditions. The 300 mg/kg BW dose showed the most optimal protective effect compared to other treatment groups, as evidenced by improvements in biochemical parameters, liver morphology, and hepatic histology, indicating that &lt;em&gt;Coffea arabica&lt;/em&gt; extract has strong potential as an effective hepatoprotective agent against CCl₄-induced liver damage&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">742</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Desi Novianti&lt;sup&gt;1*&lt;/sup&gt;, I Nyoman Ehrich Lister&lt;sup&gt;2&lt;/sup&gt;, Ali Napiah Nasution&lt;sup&gt;2&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Doctoral Program, Faculty of Medicine, Dentistry, and Health Science, Universitas Prima Indonesia, Medan 20118, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Family Medicine, Faculty of Medicine, Dentistry, and Health Science, Universitas Prima Indonesia, Medan 20118, INDONESIA&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Babiker Bashir Haroun Baraka</style></author><author><style face="normal" font="default" size="100%">Bhagya Venkanna Rao</style></author><author><style face="normal" font="default" size="100%">Tanuja Krishnamurthy</style></author><author><style face="normal" font="default" size="100%">Ramya Vasudev</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Housing In An Enriched Environment Enhances The Neuroprotective Effect Of Celastrus Paniculatus And Tribulus Terrestris In An Animal Model Of Chronic Stress</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Chronic Immobilization stress</style></keyword><keyword><style  face="normal" font="default" size="100%">Depression</style></keyword><keyword><style  face="normal" font="default" size="100%">Enriched Environment</style></keyword><keyword><style  face="normal" font="default" size="100%">Hippocampus</style></keyword><keyword><style  face="normal" font="default" size="100%">Neurotrophic factor</style></keyword><keyword><style  face="normal" font="default" size="100%">Pro-inflammatory cytokines</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">191-202</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Prolonged exposure to stress can contribute to depressive episodes. Preclinical studies have shown that stimuli like environmental enrichment (EE) can produce beneficial effects against stress by positively modulating neuroplasticity, neurochemistry, and behaviour. Hence, we explored whether exposure to EE can augment the neuroprotective activities of &lt;em&gt;Celastrus paniculatus&lt;/em&gt; (CP) and &lt;em&gt;Tribulus terrestris&lt;/em&gt; (TT) in stressed conditions. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Rats were placed in immobilisation bags and stressed for two hours a day for ten days. After that, these stressed rats were treated by CP or TT, alone or in combination with enriched housing. Behavioural analysis in elevated plus maze, open field, forced swim and sucrose preference tests. The novel object recognition test and the rewarded alteration test on the T-maze were used to assess working memory. The brain-derived neurotrophic factor, interleukin-6, and tumour necrotic factor-alpha were measured in the hippocampus and prefrontal cortical tissues following stress and herbal treatment combined with an enriched environment.&lt;strong&gt; Results: &lt;/strong&gt;We found that &lt;em&gt;Celastrus paniculatus&lt;/em&gt; and &lt;em&gt;Tribulus terrestris&lt;/em&gt;, combined with an enriched environment, produced a synergistic neuroprotective effect. CP + EE and TT + EE improved working memory and recognition memory in CIS animals, but they also reduced anxiety and depressive-like behaviours. TNF-α and IL-6 levels were decreased while brain-derived neurotrophic factor levels were raised in the frontal cortex and hippocampus regions, respectively.&lt;strong&gt; Conclusion: &lt;/strong&gt;Our results show that living in an enriched environment can improve CP and TT neuromodulatory activities, highlighting the potential of combining sensory-motor interventions with herbal remedies for psychiatric disorders.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">191</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Babiker Bashir Haroun Baraka&lt;sup&gt;1,2&lt;/sup&gt;, Bhagya Venkanna Rao&lt;sup&gt;1*&lt;/sup&gt;, Tanuja Krishnamurthy&lt;sup&gt;1&lt;/sup&gt;, Ramya Vasudev&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, KLE College of Pharmacy, KLE Academy of Higher Education and Research Rajajinagar, Bengaluru-560010, Karnataka, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Dr.Prabhakar B Kore Basic Science Research Centre, KLE College of Pharmacy, KLE Academy of Higher Education and Research Rajajinagar, Bengaluru-560010, Karnataka, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Arman Yurisaldi Saleh</style></author><author><style face="normal" font="default" size="100%">Dwi Arwandi Yogi Saputra</style></author><author><style face="normal" font="default" size="100%">Riezky Valentina</style></author><author><style face="normal" font="default" size="100%">Tirta Darmawan Susanto</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">How Extensively is Herbal Medicine Used as a Therapy for Insomnia? A Bibliometric Study</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antiepileptic</style></keyword><keyword><style  face="normal" font="default" size="100%">Bibliometric</style></keyword><keyword><style  face="normal" font="default" size="100%">Carbamazepine</style></keyword><keyword><style  face="normal" font="default" size="100%">Neuroprotective</style></keyword><keyword><style  face="normal" font="default" size="100%">Riluzole</style></keyword><keyword><style  face="normal" font="default" size="100%">Topiramat</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">342-364</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;This bibliometric study explores the use of herbal medicine as a treatment for insomnia, identifying trends and gaps in existing literature. It provides a comprehensive overview of the current state of research, guiding future efforts and improving care quality for insomnia patients. &lt;strong&gt;Materials and methods: &lt;/strong&gt;This research aims to explore the evolution of scientific disciplines by finding and identifying trends, patterns and correlations in scientific texts related to certain topics. The focus of this study was on insomnia, therapy, and &quot;herbal medicine&quot; using both quantitative and qualitative analysis. &lt;strong&gt;Results and discussion:&lt;/strong&gt; The study evaluates the use of herbal medicine for insomnia, finding a significant increase in publications but a lack of information on correct dosage. This highlights a gap in literature and calls for further research on dosage and methodological standards to improve its effectiveness.; and &lt;strong&gt;Conclusions:&lt;/strong&gt; The study confirms the effectiveness of herbal medicine as an insomnia therapy, but highlights the need for further research on appropriate dosage for safer and more effective treatment. This research was conducted in January 2025.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">342</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Arman Yurisaldi Saleh&lt;sup&gt;1*&lt;/sup&gt;, Dwi Arwandi Yogi Saputra&lt;sup&gt;2&lt;/sup&gt;, Riezky Valentina&lt;sup&gt;3&lt;/sup&gt;, Tirta Darmawan Susanto&lt;sup&gt;4&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Neurology Department Faculty of Medicine UPN Veteran Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Public Health Sciences, Faculty of Medicine, UPN Veteran Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Neurology Department Faculty of Medicine UPN Veteran Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Family Medicine and Primary Care Department, Universitas Pelita Harapan, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Uratchat Vichaidit</style></author><author><style face="normal" font="default" size="100%">Chuntida Kamalashiran</style></author><author><style face="normal" font="default" size="100%">Kammal Kumar Pawa</style></author><author><style face="normal" font="default" size="100%">Pratya Phetkate</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hydrolyzed Collagen Tonic Drink Prevents Worsening of Skin Parameters and Improves Photoaging Classification in Healthy Thai Women: A Randomized Controlled Trial</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Dermal aging</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydrolyzed collagen</style></keyword><keyword><style  face="normal" font="default" size="100%">photoaging</style></keyword><keyword><style  face="normal" font="default" size="100%">Skin elasticity</style></keyword><keyword><style  face="normal" font="default" size="100%">Wrinkle</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2025</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2025</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">17</style></volume><pages><style face="normal" font="default" size="100%">644-652</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Skin aging represents a significant public health burden globally, with Southeast Asian populations experiencing accelerated photoaging due to intensive environmental ultraviolet exposure. &lt;strong&gt;Aim: &lt;/strong&gt;To evaluate the preventive efficacy of hydrolyzed collagen tonic drink on skin aging parameters in healthy Thai women. &lt;strong&gt;Methods: &lt;/strong&gt;A double-blind, randomized controlled trial was conducted with 135 Thai women aged 40-60 years. Participants were randomized to receive either hydrolyzed fish collagen peptides with supportive nutrients (n=67) or active fruit juice control (n=68) daily for 12 weeks. Primary outcomes included skin microtopography parameters measured by Visioscan, skin elasticity assessed by Cutometer, and clinical photoaging classification using Glogau scale. Secondary outcomes examined molecular biomarker changes in procollagen Type I synthesis. &lt;strong&gt;Results:&lt;/strong&gt; The collagen group demonstrated significantly attenuated skin surface deterioration compared to placebo. The Wrinkles parameter showed significant betweengroup differences at week 8 (-100.43 units, p=0.001). Smoothness parameter exhibited protective effects with significant between-group differences at week 8 (-80.08 units, p=0.002). Gross elasticity improved significantly within the collagen group at week 12 (p=0.033). Procollagen Type I synthesis demonstrated superior maintenance in the collagen group versus placebo (between-group percent change difference, p=0.002). Both groups achieved comparable Glogau classification improvements (23.9% versus 20.6%). &lt;strong&gt;Conclusion: &lt;/strong&gt;Daily hydrolyzed collagen supplementation with supportive nutrients effectively prevented skin surface parameter deterioration in Thai women, demonstrating meaningful preservation of skin integrity through medium effect sizes for key parameters. These findings support nutritional approaches as complementary strategies for photoaging management in high ultraviolet-exposure populations&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">644</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Uratchat Vichaidit&lt;sup&gt;1&lt;/sup&gt;, Chuntida Kamalashiran&lt;sup&gt;1&lt;/sup&gt;, Kammal Kumar Pawa&lt;sup&gt;1&lt;/sup&gt;, Pratya Phetkate&lt;sup&gt;1*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Integrative Medicine, Chulabhorn International College of Medicine, Thammasat University (Rangsit Campus), Pathum Thani, 12120, THAILAND.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sofia Wardhani</style></author><author><style face="normal" font="default" size="100%">Aryati Aryati</style></author><author><style face="normal" font="default" size="100%">Bambang Purwanto</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">HBOT2 Preconditioning Prolonged Inflammation After Decompression Diving</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">HBO2 preconditioning</style></keyword><keyword><style  face="normal" font="default" size="100%">IL-1a</style></keyword><keyword><style  face="normal" font="default" size="100%">MDA</style></keyword><keyword><style  face="normal" font="default" size="100%">Syndecan-1</style></keyword><keyword><style  face="normal" font="default" size="100%">VCAM-1</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">1192-1195</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;The mechanism involved in HBO&lt;sub&gt;2&lt;/sub&gt; preconditioning in preventing inflammation in diving is still unclear. Syndecan-1, which is an important part of glycocalyx, has never been studied for its involvement in HBO&lt;sub&gt;2&lt;/sub&gt; preconditioning to prevent inflammation in decompression diving. This study aims to determine how HBO&lt;sub&gt;2&lt;/sub&gt; preconditioning impacts inflammation through Syndecan-1, MDA, and IL-1a markers.&lt;strong&gt; Method:&lt;/strong&gt; This study is a true experimental post-test design. Forty male 12- to 14-year-old Sprague Dawley rats were divided into four groups. HBO&lt;sub&gt;2 &lt;/sub&gt;and decompression diving were carried out in an animal hyperbaric chamber. All data were collected 12 and 24 hours after the decompression diving.&lt;strong&gt; Result: &lt;/strong&gt;The incidence of decompression sickness was less frequent in the HBO&lt;sub&gt;2 &lt;/sub&gt;preconditioning treatment group as opposed to the control group (4 vs 9) but did not reach a significant level (p &amp;gt; 0.05). All parameters showed no difference between the control and treatment groups 12 hours after the dive (p &amp;gt; 0.05). Twenty-four hours after diving, the treatment group demonstrated substantially elevated IL-1a levels in comparison to the control group (p = 0.030), and the increase of IL-1a in the treatment group is significant (p = 0.001). Although MDA levels did not reach significant, the treatment group's increase in MDA levels 24 hours after diving was greater than that of the control group. Meanwhile, The treatment group had a smaller reduction in Syndecan-1 levels in comparison to the control group following diving 24 hours later. &lt;strong&gt;Conclusion:&lt;/strong&gt; HBO&lt;sub&gt;2&lt;/sub&gt; preconditioning prolongs the inflammation, as evidenced by increased levels of MDA, Syndecan-1, and IL-1a, even though it can prevent decompression sickness. Further research is needed to find the right time and dose of HBO&lt;sub&gt;2&lt;/sub&gt; preconditioning to shorten the inflammation time.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1192</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sofia Wardhani&lt;sup&gt;1&lt;/sup&gt;, Aryati Aryati&lt;sup&gt;2*&lt;/sup&gt;, Bambang Purwanto&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Doctoral Program of Medical Science, Faculty of Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Clinical Pathology, Faculty of Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Medical Physiology and Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sahmad</style></author><author><style face="normal" font="default" size="100%">Andi Zulkifli Abdullah</style></author><author><style face="normal" font="default" size="100%">Muh. Syafar</style></author><author><style face="normal" font="default" size="100%">Indahwaty Sidin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Health Action Process Approach in Non-Communicable Diseases: A Systematic Review</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Behaviour change</style></keyword><keyword><style  face="normal" font="default" size="100%">Health action process approach</style></keyword><keyword><style  face="normal" font="default" size="100%">Non-communicable diseases.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">966-974</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Epidemiological research has indicated that the deleterious effects of non-communicable disease can be prevented through participation in health behaviours. The HAPA is a dual-phase model that identifies the determinants of the initiation and maintenance of health behaviour. The aim of this study was to systematically map the Health Action Process Approach (HAPA)- based interventions in non-communicable diseases in relation to the type of intervention, the target groups and the constructs of the HAPA model that are used in the study and to assess the clinical relevance of the studies. &lt;strong&gt;Methods:&lt;/strong&gt; This review study complies with the Preferred Reporting Items for Systematic review and Meta-analysis (PRISMA) version 2020. The search for relevant literature involved PubMed, Sciencedirect, Willey online Library and Proquest databases for the studies published in 2000 to 2023 period. Quality of the study was assessed using CASP, and the Risk of Bias using Cochrane RoB tool. &lt;strong&gt;Results:&lt;/strong&gt; In databases search, there are 912 studies. The results for eligibility resulted in 18 articles consist of 13 observational studies, and 5 experimental studies. Discussion: Physical activity, healthy diet behaviour, and medication adherence were the targeted behaviour. In the majority of the studies, the targeted intervention was physical activity and the population consisted of adult patients. &lt;strong&gt;Conclusion&lt;/strong&gt;: All studies used only a selection of the HAPA constructs. Therefore, only a minority of the studies can be considered real HAPA intervention studies.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">966</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sahmad&lt;sup&gt;1*&lt;/sup&gt;, Andi Zulkifli Abdullah&lt;sup&gt;2&lt;/sup&gt;, Muh. Syafar&lt;sup&gt;3&lt;/sup&gt;, Indahwaty Sidin&lt;sup&gt;4&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Phd student, College of public health,&amp;nbsp;Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Professor, Department of Epidemiology, College of public health,&amp;nbsp;Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Professor, Department of Health behavioral science, College of public health,&amp;nbsp;Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Associate Professor, Department of Hospital Management, College of public health,&amp;nbsp;Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rochfika</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author><author><style face="normal" font="default" size="100%">Aminuddin Syam</style></author><author><style face="normal" font="default" size="100%">Agus Bintara Birawida</style></author><author><style face="normal" font="default" size="100%">Syafri Kamsul Arif</style></author><author><style face="normal" font="default" size="100%">A. Indahwaty Sidin</style></author><author><style face="normal" font="default" size="100%">Muh. Nasrum Massi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Health Risk Assessment and Monte Carlo Simulation of Microorganism Aerosol Pollution at the Intensive Care Unit of Dr. Wahidin Sudirohusodo Hospital. Makassar</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bioaerosol</style></keyword><keyword><style  face="normal" font="default" size="100%">Health risk assessment</style></keyword><keyword><style  face="normal" font="default" size="100%">Microorganisms</style></keyword><keyword><style  face="normal" font="default" size="100%">Monte carlo</style></keyword><keyword><style  face="normal" font="default" size="100%">Pollution</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">1170-1176</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Microorganism pollutants can be bacteria, fungi and spores in the room. Microorganisms that are distributed in space are known as bioaerosols. The spread of bioaerosol in hospitals can result in danger to human health, especially for patients with weakened immune systems. Risk assessment is very important for an organization or institution to overcome current and future risks related to contamination. The QMRA approach has been applied to inform standards for the microbiological quality of food, water, air, and touched surfaces. The method uses descriptive analytics with a literature review design. Data was obtained through searches on the electronic databases Pubmed , Elsevier , and Google Scholar. Keyword terms such as: (Bioaerosol * and Airborne * and Infections * and Hospital *) , ( Bioaerosol * and Microorganisms * and Inhalation ) , ( Airborne * and Microbial and * Hospital * or Intensive Room *) , ( Bioaerosol * Quantitative Microbial Risk Assessment (QMRA)* and Hospital-Acquired Infection* and Intensive Care unit ) . health risks AND sensitivity AND aerosol pollution AND microorganisms OR fungi OR bacteria AND montercarlo AND intensive care OR hospital rooms: (Bioaerosol * and Airborne * and Infections * and Hospital *) , ( Bioaerosol * and Microorganisms * and Inhalation ) , ( Airborne * and Microbial and * Hospital * or Intensive Room *) , (Bioaerosol * Quantitative Microbial Risk Assessment (QMRA) * and Hospital-Acquired Infection * and Intensive Care unit ) . health risks AND sensitivity AND aerosol pollution AND microorganisms OR fungi OR bacteria AND monter carlo AND intensive care OR hospital rooms are used. The search covered research conducted over the past ten years, from 2012 to 2022. Of the 27 articles found using the search terms, seventeen articles were selected for examination. The four categories of analysis are population, type of study, aims, and findings. According to research, one of the parameters for evaluating indoor environmental quality is bioaerosol. Microbial bioaerosol media in the air are ambient air and indoor air. The routes of exposure can be through ingestion/swallowing, direct contact and inhalation/inhalation. The cause of hospital infections is because hospital environmental conditions do not meet the requirements, causing high levels of room air germs. Poor hospital indoor air quality can cause HAIs. Therefore increasing levels of mechanical or natural ventilation as well as regular cleaning and maintenance activities can play an important role in improving indoor air quality.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1170</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Rochfika&lt;sup&gt;1&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;2&lt;/sup&gt;, Aminuddin Syam&lt;sup&gt;3&lt;/sup&gt;, Agus Bintara Birawida&lt;sup&gt;2&lt;/sup&gt;, Syafri Kamsul Arif&lt;sup&gt;4&lt;/sup&gt;, A. Indahwaty Sidin&lt;sup&gt;5&lt;/sup&gt;, Muh. Nasrum Massi&lt;sup&gt;6&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Doctoral Program and Department of Public Health, Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Environmental Health, Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Nutritional Science, Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Anesthesiology and Intensive Therapy, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Hospital Management, Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Microbiology Medical Faculty, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Vimala Yerramilli</style></author><author><style face="normal" font="default" size="100%">Mahendra Singh</style></author><author><style face="normal" font="default" size="100%">Ishwar Singh</style></author><author><style face="normal" font="default" size="100%">Laxman Nagar</style></author><author><style face="normal" font="default" size="100%">Jitendra Singh</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepato-restorative Activity of Methanolic Extracts of Coccinia grandis L. Voigt. in CCl4 - Intoxicated Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Callus</style></keyword><keyword><style  face="normal" font="default" size="100%">CCl4</style></keyword><keyword><style  face="normal" font="default" size="100%">Coccinia grandis</style></keyword><keyword><style  face="normal" font="default" size="100%">GC-MS</style></keyword><keyword><style  face="normal" font="default" size="100%">Liver</style></keyword><keyword><style  face="normal" font="default" size="100%">Silymarin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">1096-1102</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Coccinia grandis&lt;/em&gt; has pharmacological activities such as antioxidant, anti-ulcer, antiinflammatory, anti-hypersensitive, anti-hyperglycaemic, anti-cancer and hepatoprotective.&lt;strong&gt; Objective: &lt;/strong&gt;This work is aimed to investigate an alternative low-cost green drug with hepatoprotective potential from methanolic extract of the leaf, stem and their corresponding calli of &lt;em&gt;Coccinia grandis&lt;/em&gt;. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;Using 42 Albino Wistar rats divided into seven groups each group containing 6 rats. 1.5ml/kg bw of CCl&lt;sub&gt;4&lt;/sub&gt; diluted in olive oil was orally injected for fourteen days and methanolic extracts of parent plant parts, callus and silymarin, and on the last day of treatment, experimental rats were anesthetized, blood and organ removed for the biochemical and histopathological analysis.&lt;strong&gt; Results:&lt;/strong&gt; This work is aimed to investigate an alternative low-cost green drug with hepatoprotective potential. Liver damage was induced by CCl&lt;sub&gt;4&lt;/sub&gt; (1.5 ml/kg body weight) in Wistar albino rats and recovery was noted by treating with Silymarin (100mg/kg bw), a known standard herbal drug and by treating with crude methanolic extract of leaf and stem parts of &lt;em&gt;Coccinia grandis&lt;/em&gt; and their corresponding calli (leaf callus and stem callus at 180mg/kg bw) in terms of marked decrease in CCl&lt;sub&gt;4-&lt;/sub&gt; increased SGOT (Serum glutamic oxaloacetic transaminase), SGPT (Serum glutamic pyruvic transaminase), ALP (Alkaline phosphatase), TB (Total bilirubin) and rise in TP (Total protein) compared to untreated control group. Histopathological studies of hepatocytes provide evidence of the centrilobular vacuolar degeneration and recovery by Silymarin or treatment with plant and callus extracts. &lt;strong&gt;Conclusion:&lt;/strong&gt; Biochemical and histopathological examination proved the hepatoprotective potential of calli and parent plant parts (leaf, stem) of &lt;em&gt;Coccinia grandis&lt;/em&gt;.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1096</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Vimala Yerramilli&lt;sup&gt;1*&lt;/sup&gt;, Mahendra Singh&lt;sup&gt;1&lt;/sup&gt;,Ishwar Singh&lt;sup&gt;2&lt;/sup&gt;, Laxman Nagar&lt;sup&gt;3&lt;/sup&gt;, Jitendra Singh&lt;sup&gt;4&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1,2&lt;/sup&gt;,Department of Botany, Chaudhary Charan Singh, University, Meerut, 250004-INDIA&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1, 3,4&lt;/sup&gt;Department of Microbiology, Chaudhary Charan Singh, University, Meerut, 250004-INDIA&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Febria Rizky Patikawa</style></author><author><style face="normal" font="default" size="100%">Dyah Fauziah</style></author><author><style face="normal" font="default" size="100%">Willy Sandhika</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">HIF-1α and VEGF Expression in Adult-type Diffuse High-Grade Astrocytoma</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Astrocytoma IDH mutant grade 4</style></keyword><keyword><style  face="normal" font="default" size="100%">Glioblastoma IDH wild type</style></keyword><keyword><style  face="normal" font="default" size="100%">Glioma</style></keyword><keyword><style  face="normal" font="default" size="100%">HIF-1α</style></keyword><keyword><style  face="normal" font="default" size="100%">VEGF</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">466-470</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Gliomas stand as the prevalent primary malignant brain tumors in adults with astrocytoma being more common than oligodendroglioma. Based on isocitrate dehydrogenase (IDH) status, astrocytomas are classified as astrocytoma with mutated IDH and astrocytoma with wild-type IDH (glioblastoma). Tumor growth relies on angiogenesis, a process facilitated by key factors such as Vascular Endothelial Growth Factor (VEGF) and Hypoxia Inducible Factor-1α (HIF-1α). This study aims to investigate the VEGF and HIF-1α expression profiles in grade 4 astrocytomas, encompassing both mutated IDH and wild-type IDH.&lt;strong&gt; Method:&lt;/strong&gt; This study was conducted on 43 formalin fixed paraffin embedded (FFPE) materials of surgical specimens from adult-type grade 4 astrocytoma. Immunohistochemistry with IDH1 R132H was carried out to determine the IDH status, followed by assessment of HIF-1α and VEGF expression using semi-quantitatively utilizing immunoreactive score (IRS), and categorized as negative, weak, moderate, and strong. &lt;strong&gt;Results:&lt;/strong&gt; Statistical analysis revealed no disparity in HIF-1α expression between both tumor types, nor was there a difference in VEGF expression in both tumor types, yet a positive association was established between VEGF and HIF-1α expression levels in IDH mutant and wild type of grade 4 astrocytoma with moderate strength (r=0.433). &lt;strong&gt;Conclusion:&lt;/strong&gt; HIF-1α and VEGF are positively linked, despite the IDH status, and simultaneously work to promote angiogenesis in diffuse high-grade astrocytoma.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">466</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Febria Rizky Patikawa, Dyah Fauziah*, Willy Sandhika&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;Department of Anatomical Pathology, Faculty of Medicine, Universitas Airlangga – Dr. Soetomo Academic General Hospital, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Atheer A. Ali</style></author><author><style face="normal" font="default" size="100%">Enas F. Kadhim</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Histological Characterization of Modified Calcite Paste as Pulpotomy Material in Partially Pulpotomized Rabbit Incisors</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Calcite</style></keyword><keyword><style  face="normal" font="default" size="100%">Calcium carbonate</style></keyword><keyword><style  face="normal" font="default" size="100%">Pulpotomy</style></keyword><keyword><style  face="normal" font="default" size="100%">Rabbit incisor</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">415-421</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; increasing the demand for vital pulp therapy (VPT) as a minimally invasive treatment, evolving the need for bio-inspired capping material to optimize the outcome with more predictable results.&lt;strong&gt; Aim: &lt;/strong&gt;is to evaluate the biological efficacy of modified calcite paste as potential material for pulpotomy in terms of pulpal inflammatory response, dentin bridge formation and morphology. &lt;strong&gt;Methods:&lt;/strong&gt; 24 lower central incisors of New Zealand rabbits were used, subdivided into two groups of 12 teeth according to sacrificing time (1 and 4 weeks), in each group, six teeth were used as the control group, the pulp is traumatically exposed and partially amputated left free of capping material, and six teeth used as the experimental group, were the amputated pulp capped with Modified Calcite (MC) paste, the cavity of both groups sealed with resin modified glass ionomere cement (pulpdent, USA).animal were sacrificed and teeth were collected for histological examination. &lt;strong&gt;Results:&lt;/strong&gt; At 1-week and 4-week periods respectively, both groups showed non-significant differences in inflammatory extent, a highly significant difference in calcific bridge formation (P=0.002) and dentin morphology (P=0.002). The MC group showed faster dentin bridge formation with favourable morphology according to the scoring system in both periods compared to the control group. &lt;strong&gt;Conclusions:&lt;/strong&gt; MC composite is a promising novel pulpotomy material.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">415</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Atheer A. Ali, Enas F. Kadhim*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Oral Diagnosis, College of Dentistry, University of Baghdad, Baghdad, IRAQ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Kinda M. Al-Taee</style></author><author><style face="normal" font="default" size="100%">Luay A. Al-Helaly</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hydrogen Sulfide and Cystathionine γ–Lyase with Oxidants and Antioxidants Levels for Patients with Epilepsy Diseases</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Cystationine γ–lyase</style></keyword><keyword><style  face="normal" font="default" size="100%">Epilepsy</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydrogen sulfide</style></keyword><keyword><style  face="normal" font="default" size="100%">Oxidative stress</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">319-322</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The research includes studying the levels of hydrogen sulphide (H2S) and cystathionine γ–lyase (CSE) with some oxidants and antioxidants in the serum of patients with epilepsy disease in Mosul city which include: malondialdehyde (MDA), peroxynitrite (ONOO-), glutathione (GSH), total bilirubin (TSB), albumin (Alb) and uric acid (UA), were measured in the patient group who suffered from epilepsy disease in Mosul city, Samples reached (116), which included: (56) samples for epilepsy patients group, and (60) for control group. The results showed there was a significant decrease in the levels of H2S, CSE, GSH, and TSB and a significant increase in the levels of MDA, ONOO-, Alb and UA in serum for epilepsy patients when Compared with the control group. The study concluded that H2S gas produced within the body and CSE suffer from low levels within the body, and they also decrease with the increase in the duration of the disease as a result of their use as protective functions in the body against epilepsy disease and developing it, by observing the levels of oxidants and antioxidants compounds and stimulating the body to increase their levels (H2S, and CSE) in various ways can lead to improving the health condition of patients.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">319</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Kinda M. Al-Taee&lt;sup&gt;1&lt;/sup&gt;, Luay A. Al- Helaly&lt;sup&gt;2,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Chemistry, College of Education for Pure Science, University of Mosul, Mosul, IRAQ.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Chemistry, College of Science, University of Mosul, Mosul, IRAQ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Titut Harnanik</style></author><author><style face="normal" font="default" size="100%">Ketut Edy Sudiarta</style></author><author><style face="normal" font="default" size="100%">Rudi Pandapotan Napitupulu</style></author><author><style face="normal" font="default" size="100%">Arif Rahman Nurdianto</style></author><author><style face="normal" font="default" size="100%">Ni Ketut Alit Darmayanti</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hyperbaric Oxygen in Animal Model of Diabetes Nephropathy: Analysis of Blood Glucose, Proteinuria and Kidney Tissue Necrosis Cells</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Blood glucose</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetes Nephropaty</style></keyword><keyword><style  face="normal" font="default" size="100%">Hyperbaric Oxygen</style></keyword><keyword><style  face="normal" font="default" size="100%">Kidney Tissue Necrosis Cells</style></keyword><keyword><style  face="normal" font="default" size="100%">Proteinuria</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">1043-1046</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Diabetic nephropathy (DN) is a microvascular complication of diabetes mellitus (DM) and is the main cause of 20 to 40 times higher mortality compared to diabetes without nephropathy. Therefore, the author wants to prove the effect of hyperbaric oxygen therapy (HBO) on changes in blood glucose levels, proteinuria and kidney tissue necrosis cells in DN animal models. This study used 27 male white rats Rattus Norvegicus strain Wistar, weighing 170 - 220 grams, aged 8-12 weeks, healthy and active, divided into 3 groups, namely the normal rats group (G0), the DN rats without HBO group (G1) and the DN rats with HBO group (G2). Making a DN model with Streptozotocin (STZ) induction 75 mg / kgBW intraperitoneally in a single dose. HBO was performed in a 2.4 ATA pressurized air chamber by inhaling 98% O2 for 3 x 30 minutes interspersed with inhaling normal air for 2 x 5 minutes for 5 consecutive days. The results showed a significant decrease in blood glucose levels p = 0.000 (p &amp;lt;0.05). In proteinuria levels, there was an insignificant decrease p = 0.077 (p &amp;gt; 0.05) in G2 compared to G1. Repair of kidney tissue damage was also indicated by a decrease in necrotic cells by 45.45% in G2 compared to G1. These results prove that HBO can repair kidney damage in DN model mice, so HBO is expected to be used as an additional therapy in cases of diabetic nephropathy.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1043</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Titut Harnanik&lt;sup&gt;1,2,*&lt;/sup&gt;, Ketut Edy Sudiarta&lt;sup&gt;1&lt;/sup&gt;, Rudi Pandapotan Napitupulu&lt;sup&gt;1&lt;/sup&gt;, Arif Rahman Nurdianto&lt;sup&gt;1&lt;/sup&gt;, Ni Ketut Alit Darmayanti&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Marine Health, Faculty of Medicine, Hang Tuah University, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Naval Health Institute Drs. Med. R. Rijadi S, Phys., Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Muh Ichsan</style></author><author><style face="normal" font="default" size="100%">Hasanuddin Ishak</style></author><author><style face="normal" font="default" size="100%">Erniwati Ibrahim</style></author><author><style face="normal" font="default" size="100%">Hasnawati Amqam</style></author><author><style face="normal" font="default" size="100%">Isra Wahid</style></author><author><style face="normal" font="default" size="100%">Syahribulan</style></author><author><style face="normal" font="default" size="100%">Rusdiyah Sudirman</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Habitat Characteristics of Aedes Sp Larval Containers and Density of Container Index (CI) In the Area Endemic and Non-Endemic to DHF In Makassar City</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Characteristics of Container Habitats</style></keyword><keyword><style  face="normal" font="default" size="100%">Endemic and Non-Endemic.</style></keyword><keyword><style  face="normal" font="default" size="100%">Larval Density</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">290-295</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;em&gt;Aedes sp &lt;/em&gt;has breeding habitats in water reservoirs or containers with relatively clear water, both inside and outside the house and in public places. The existence of containers as a breeding habitat for &lt;em&gt;Aedes sp &lt;/em&gt;mosquitoes can increase the population density of&lt;em&gt; Aedes sp&lt;/em&gt; mosquitoes, triggering high transmission of the dengu virus in the city of Makassar. The purpose of the study is to determine the characterisitic relationship of containers with the index of &lt;em&gt;aedes sp&lt;/em&gt; larvae in dengue endemism areas in Makassar city in 2022. This study is an analytical observational study. Quantitative analysis with a cross-sectional approach. The sample sampling technique is a technique with simple purposive sampling. The sample was 600 houses in endemic and non-endemic areas in makassar city. The results of this study are container types with CI density in endemic areas, namely bucket 242 (CI = 9.5), while in non-endemic areas namely bucket 298 (CI = 5.4), container materials with CI density in endemic areas namely plastic 422 (CI = 10.9), while in non-endemic areas namely plastic 482 (CI = 5.6), and container locations with CI materials and densities namely in indoor locations with plastic material 398 (CI = 8.0), while in non-endemic areas with CI materials and densities, namely in indoor locations with plastic material 455 (CI = 5.5). The results of the chi-square test in the endemic area obtained a value of p = 0.478 which means that there is no relationship between the container type and the presence of&lt;em&gt; aedes sp&lt;/em&gt; larvae in Tamamaung, Chi-square test results in non-endemic areas obtained a value of p = 0.217 which means that there is no relationship between the container type and the presence of &lt;em&gt;Aedes sp&lt;/em&gt; larvae in the new Malimangan Village. The results of the chi-square test in the endemic area obtained a value of p = 0.000 which means that there is a relationship between the location and the presence of &lt;em&gt;aedes sp &lt;/em&gt;larvae in tamamaung, and Meanwhile, the results of the Chi-Square test in non-endemic areas obtained a value of p = 0.631 which means that there is no relationship between the location and the presence of&lt;em&gt; Aedes sp &lt;/em&gt;larvae in the new malimongan. There is no relationship between CI density and endemic and nonendemic regions. All six regions fall into the moderate category. His advice for the Makassar City Health Office, especially in Tamamaung, Pisang Utara, Pampang, Malimongan Baru, Kalukuang and Rappojawa villages, is that it is necessary to conduct counseling / information about the importance of environmental cleanliness and mosquito breeding sites to residents evenly and distribute abate, so that the community can be vigilant and avoid the transmission of dengue fever&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><section><style face="normal" font="default" size="100%">290</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Muh Ichsan&lt;sup&gt;1&lt;/sup&gt;, Hasanuddin Ishak&lt;sup&gt;1,*&lt;/sup&gt;, Erniwati Ibrahim&lt;sup&gt;1&lt;/sup&gt;, Hasnawati Amqam&lt;sup&gt;1&lt;/sup&gt;, Isra Wahid&lt;sup&gt;2&lt;/sup&gt;, Syahribulan&lt;sup&gt;3&lt;/sup&gt;, Rusdiyah Sudirman&lt;sup&gt;1&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Master Program of Department of Environmental Health, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Parasitology, Faculty of Medicine, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biology, Faculty of Mathematics and Natural Sciences, Hasanuddin University, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Prasanna Mohana Bhaskaran</style></author><author><style face="normal" font="default" size="100%">Mohammed Nawar Alotaibi</style></author><author><style face="normal" font="default" size="100%">Inbaraj Susai Domnic</style></author><author><style face="normal" font="default" size="100%">Bhaskaran Ashokan</style></author><author><style face="normal" font="default" size="100%">Sudharshan Reddy Dachani</style></author><author><style face="normal" font="default" size="100%">Semmal Syed Meerasa</style></author><author><style face="normal" font="default" size="100%">Osama Mohammed Alruways</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hand Hygiene Awareness and Knowledge Among Healthcare Personnel in The Dawadmi Region of Saudi Arabia: A Cross- Sectional Survey Study</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">awareness</style></keyword><keyword><style  face="normal" font="default" size="100%">Cross infection</style></keyword><keyword><style  face="normal" font="default" size="100%">Hand hygiene</style></keyword><keyword><style  face="normal" font="default" size="100%">Healthcare workers</style></keyword><keyword><style  face="normal" font="default" size="100%">Knowledge.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">368-371</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction&lt;/strong&gt;: The outcome of patient care in healthcare settings is influenced predominantly by healthcare-associated infections (HAIs). Hand hygiene is the single most essential component in avoiding HAIs. &lt;strong&gt;Objectives:&lt;/strong&gt; The aim of the study is to evaluate the awareness and knowledge about hand hygiene among the healthcare personnel in the Dawadmi Region of Saudi Arabia. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;This cross-sectional survey study was carried out between May till September 2021. The tool (Questionnaire) was adopted from World Health Organization's Hand Hygiene Knowledge and awareness Questionnaire (revised in 2009), validated according to CROSS (Checklist for Reporting of Survey Studies) check list. &lt;strong&gt;Results:&lt;/strong&gt; A total of 300 participants were randomly enrolled, 60 were nursing assistants, 140 nurses, and 100 residents, were enrolled in this study. With respect to years of experience in hand washing, 123 participants had 1–5 years (41%), 6–10 years (80%), 11–20 years (77%), and greater than 30 years of participation (6.67%). Concerning the education of hand washing and hygiene, training programs were attended by 230 participants (76.67%), and 70 participants (23.33%) did not attend the latest training program conducted by each institution. Most of them (83.33%) were using alcohol for hand hygiene. &lt;strong&gt;Conclusions&lt;/strong&gt;: This study has clearly shown the requirement of an in-depth appraisal of important issues of compliance and patient safety. Educational interventions to recognize the hand hygiene opportunities, improved availability of hand hygiene facilities and multifaceted approach to tackle various barriers (poor attitude, workload, etc) of adherence are needed to be accorded priority.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">368</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Prasanna Mohana Bhaskaran&lt;sup&gt;1&lt;/sup&gt;, Mohammed Nawar Alotaibi&lt;sup&gt;2&lt;/sup&gt;, Inbaraj Susai Domnic&lt;sup&gt;1,*&lt;/sup&gt;, Bhaskaran Ashokan&lt;sup&gt;3&lt;/sup&gt;, Sudharshan Reddy Dachani&lt;sup&gt;4&lt;/sup&gt;, Semmal Syed Meerasa&lt;sup&gt;3&lt;/sup&gt;, Osama Mohammed Alruways&lt;sup&gt;5&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty, College of Medicine - Al-Dawadmi Campus, Shaqra University&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Final year Medical Student, College of Medicine - Al-Dawadmi Campus, Shaqra University&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Faculty, College of Medicine - Shaqra Campus, Shaqra University&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Faculty, College of Pharmacy - Al-Dawadmi Campus, Shaqra University&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Second year Medical Student, College of Medicine - Al-Dawadmi Campus, Shaqra University&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Andi Asrina</style></author><author><style face="normal" font="default" size="100%">Rizal Payapo</style></author><author><style face="normal" font="default" size="100%">Fairus Concerned Idris</style></author><author><style face="normal" font="default" size="100%">Sukri Palutturi</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Health Behavior and Social Support in Postpartum Mothers Treatment in Ba'ukup Tradition in Maluku</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ba'ukup</style></keyword><keyword><style  face="normal" font="default" size="100%">Health.</style></keyword><keyword><style  face="normal" font="default" size="100%">Postpartum</style></keyword><keyword><style  face="normal" font="default" size="100%">Tradition</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">438-442</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;The maternal mortality rate is still high in Indonesia and one of the priorities of government agendas to decrease, one of them is giving good treatment to Postpartum Mothers. This is very important because in the Postpartum periode, there is a risk to get bleeding and infection that has an impact on maternal death. Many Postpartum Mothers' treatment is based on local wisdom, but not all give benefits to Postpartum Mothers. The aim of this study was to analyze Ba’ukup Tradition as a Postpartum Mothers Treatment Based on Local Wisdom in Negeri Luhu, Huamual, Maluku. This study used Qualitative method with ethnographic approach. The informants were 8 people which consisted of 1 supporting informant (Traditional Midwife/ Mama Biang), 1 Midwife as a key informant and 6 ordinary informants were selected purposively with the criteria of Mothers who are carrying out Ba'ukup. Thematic data analysis and data validity used triangulation technique. The results showed that Ba’ukup tradition is an ancestral heritage felt psychically and beneficially by Postpartum Mothers such as feeling more relaxed, sleeping better, sweating and helping to increase breast milk production. Meanwhile, Ba’ukup tradition is a local wisdom in Postpartum Mothers treatment so that in its implementation, it requires the assistance of health workers because during the Postpartum period, there is a risk to get bleeding and other complications. It is suggested that there are persuasive approach and communication between health workers and the society in order to build a harmonious trust in local traditions and health services.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">438</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Andi Asrina&lt;sup&gt;1,*&lt;/sup&gt;, Rizal Payapo&lt;sup&gt;1&lt;/sup&gt;, Fairus Concerned Idris&lt;sup&gt;1&lt;/sup&gt;, Sukri Palutturi&lt;sup&gt;2&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Health Promotion Concentration, Faculty of Public Health, Indonesian Muslim University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Health Administration and Policy, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Environmental Health, Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Zainuddin</style></author><author><style face="normal" font="default" size="100%">Andi Zulkifli Abdullah</style></author><author><style face="normal" font="default" size="100%">Nurhaedar Jafar</style></author><author><style face="normal" font="default" size="100%">Suriah</style></author><author><style face="normal" font="default" size="100%">Nursalam</style></author><author><style face="normal" font="default" size="100%">Darmawansyah</style></author><author><style face="normal" font="default" size="100%">Syahrul Syahrul</style></author><author><style face="normal" font="default" size="100%">Wahiduddin</style></author><author><style face="normal" font="default" size="100%">Widiantoro</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Health Literacy Brisk Walking Exercise on Clinical Outcomes of Blood Sugar in Patients with Type 2 Diabetes Mellitus in Indonesia</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Blood Sugar (HbA1c).</style></keyword><keyword><style  face="normal" font="default" size="100%">DMT2</style></keyword><keyword><style  face="normal" font="default" size="100%">Health Literacy Brisk walking</style></keyword><keyword><style  face="normal" font="default" size="100%">Physical Activity</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">433-438</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Regular Physical activity (PA) is recommended for patients with type 2 diabetes because it has a beneficial effect on metabolic risk factors for the development of diabetic complications. This study was designed to determine the effect of health literacy (HL) brisk walking on clinical outcomes (HbA1c) and PA in patients with DMT2. &lt;strong&gt;Method:&lt;/strong&gt; In using the Quasi Experimental method using the Two group pre-posttest design approach. Research subjects were allocated for the provision of Health literacy Brisk walking (n-30, 30 completed) and the usual care group (n = 30,30 completed). Health literacy brisk walking participants received weekly scheduled information via WhatsApp group with monitoring to walk 3-5 times for 150 minutes/week, while the control group only received regular care from the Chronic Disease Management (Prolanis) program. &lt;strong&gt;Results:&lt;/strong&gt; Sixty T2DM patients (thirty in the intervention group and thirty in the control group) were examined. The results showed that Health literacy Brisk walking with Whatsapp Group Monitoring in the intervention group was significantly higher than usual care from the Chronic Disease Management program (Prolanis) in the control group towards changes in HbA1c and PA after 3 months (p&amp;lt;0.05). &lt;strong&gt;Conclusion: &lt;/strong&gt;Health literacy brisk walking related to diabetes can be a modifiable factor related to HbA1c for DMT2 patients. The findings indicate the need for health care providers to be able to consider brisk walking PA as a solution in controlling blood sugar (HbA1c).&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">433</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Zainuddin&lt;sup&gt;1,2&lt;/sup&gt;, Andi Zulkifli Abdullah&lt;sup&gt;2,*&lt;/sup&gt;, Nurhaedar Jafar&lt;sup&gt;3&lt;/sup&gt;, Suriah&lt;sup&gt;4&lt;/sup&gt;, Nursalam&lt;sup&gt;5&lt;/sup&gt;, Darmawansyah&lt;sup&gt;6&lt;/sup&gt;, Syahrul Syahrul&lt;sup&gt;7&lt;/sup&gt;, Wahiduddin&lt;sup&gt;8&lt;/sup&gt;, Widiantoro&lt;sup&gt;9&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;10&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Public Health, Doctoral Student of Public Health, Hasanuddin University, Department of Nursing, STIKes Tanawali, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Epidemiology, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Nutrition Science, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Health Promotion, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Department of Nursing, Faculty of Nursing, Airlangga University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Health Administration and policy study program, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Department of Nursing, Faculty of Nursing, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;8&lt;/sup&gt;Department of Epidemiology, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;9&lt;/sup&gt;School of Health sciences Santoo Borromeus, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;10&lt;/sup&gt;Department of Environmental Health, Faculty of Public Health, Hasanuddin University, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sunadi</style></author><author><style face="normal" font="default" size="100%">Saddam Al Aziz</style></author><author><style face="normal" font="default" size="100%">Fadhilah Fitri</style></author><author><style face="normal" font="default" size="100%">Devni Prima Sari</style></author><author><style face="normal" font="default" size="100%">Muhammad Raffi Ghifari</style></author><author><style face="normal" font="default" size="100%">Rismi Verawati</style></author><author><style face="normal" font="default" size="100%">Nita Yessirita</style></author><author><style face="normal" font="default" size="100%">Oski Illiandri</style></author><author><style face="normal" font="default" size="100%">Riso Sari Mandeli</style></author><author><style face="normal" font="default" size="100%">Devi Purnamasari</style></author><author><style face="normal" font="default" size="100%">Putri Azhari</style></author><author><style face="normal" font="default" size="100%">Rahadian Zainul</style></author><author><style face="normal" font="default" size="100%">Viol Dhea Kharisma</style></author><author><style face="normal" font="default" size="100%">Vikash Jakhmola</style></author><author><style face="normal" font="default" size="100%">Maksim Rebezov</style></author><author><style face="normal" font="default" size="100%">ANM Ansori</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatitis E Inhibited by Rosmarinic Acid Extract from Clove Plant (Syzygium Aromaricum) through Computational Analysis</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Hepatitis E</style></keyword><keyword><style  face="normal" font="default" size="100%">Molecular Docking.</style></keyword><keyword><style  face="normal" font="default" size="100%">Rosmarinic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Syzygium aromaricum</style></keyword><keyword><style  face="normal" font="default" size="100%">Tyrosine FYN</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">518-523</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;This study aims to evaluate the potential of Rosmarinic Acid as an inhibitor against Hepatitis E by interacting with the active site of the Tyrosine FYN protein. Computational approaches were employed to predict the molecular interactions between Rosmarinic Acid and Tyrosine FYN. The research methodology involved the use of software such as Pymol, Pyrex, Protein Plus, and the Lepinski Rule. Docking analysis was conducted using Pymol to obtain information about the binding energy between Rosmarinic Acid and Tyrosine FYN. The results of the analysis showed that Rosmarinic Acid exhibited a Binding Affinity of -8.3, -8, and -7.9, indicating a strong affinity towards the target protein. Additionally, Root Mean Square Deviation (RMSD) values of 0, 15.905, and 17.014 were used to assess the stability of the formed protein-ligand complex. Analysis using Protein Plus revealed interactions between Rosmarinic Acid and Tyrosine FYN. Furthermore, analysis using the Lepinski Rule to examine the physicochemical properties of Rosmarinic Acid indicated that the molecule had a mass of 360, 5 hydrogen bond donors, 8 hydrogen bond acceptors, a log P value of 1.76, and a molar reactivity of 89.8. These findings highlight the potential of Rosmarinic Acid as an inhibitor of Hepatitis E through its interaction with the Tyrosine FYN protein, providing a basis for the development of potential new therapies in the treatment of this disease.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article </style></work-type><section><style face="normal" font="default" size="100%">518</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sunadi1, Saddam Al Aziz&lt;sup&gt;2&lt;/sup&gt;, Fadhilah Fitri&lt;sup&gt;3&lt;/sup&gt;, Devni Prima Sari&lt;sup&gt;4&lt;/sup&gt;, Muhammad Raffi Ghifari&lt;sup&gt;5&lt;/sup&gt;, Rismi Verawati&lt;sup&gt;6&lt;/sup&gt;, Nita&amp;nbsp;Yessirita&lt;sup&gt;7&lt;/sup&gt;, Oski Illiandri&lt;sup&gt;8&lt;/sup&gt;, Riso Sari Mandeli&lt;sup&gt;9&lt;/sup&gt;, Devi Purnamasari&lt;sup&gt;10&lt;/sup&gt;, Putri Azhari&lt;sup&gt;11&lt;/sup&gt;, Rahadian Zainul&lt;sup&gt;6,12,*&lt;/sup&gt;, Viol&amp;nbsp;Dhea Kharisma&lt;sup&gt;13,14&lt;/sup&gt;, Vikash Jakhmola&lt;sup&gt;15&lt;/sup&gt;, Maksim Rebezov&lt;sup&gt;16,17&lt;/sup&gt;, ANM Ansori&lt;sup&gt;13,15&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Agrotechnology Study Program, Faculty of Agriculture, Universitas Tamansiswa, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Mathematics Department, Universitas Negeri Padang, Padang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Statistics Department, Universitas Negeri Padang, Padang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Mathematics Department, Universitas Negeri Padang, Padang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Informatics Engineering, Faculty of Computer Sciences, Universitas Brawijaya, Malang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;7&lt;/sup&gt;Agricultural Product Technology Study Program, Faculty of Agriculture, Universitas Ekasakti, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;8&lt;/sup&gt;Department of Biomedicine, Faculty of Medicine, Universitas Lambung Mangkurat, Banjarmasin, South Kalimantan, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;9&lt;/sup&gt;Environmental and Policy Researcher, Environmental Science Program, Universitas Negeri Padang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;10&lt;/sup&gt;Department of Radiology, Universitas Awalbros, Pekanbaru, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;11&lt;/sup&gt;Department of Agricultural Technology, Faculty of Agricultural Technology, Universitas Andalas, Padang, West Sumatra, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;12&lt;/sup&gt;Center for Advanced Material Processing, Artificial Intelligence, and Biophysic Informatics (CAMPBIOTICS), Universitas Negeri Padang, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;13&lt;/sup&gt;Faculty of Science and Technology, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;14&lt;/sup&gt;Generasi Biologi Indonesia Foundation, Gresik, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;15&lt;/sup&gt;Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;16&lt;/sup&gt;Department of Scientific Research, V. M. Gorbatov Federal Research Center for Food Systems, Moscow, RUSSIAN FEDERATION.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;17&lt;/sup&gt;Faculty of Biotechnology and Food Engineering, Ural State Agrarian University, Yekaterinburg, RUSSIAN FEDERATION.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ali Mohammed Zaki Al-Jaberi</style></author><author><style face="normal" font="default" size="100%">Sabaa Ali Mohammed Al-Fadal</style></author><author><style face="normal" font="default" size="100%">Thukaa Zuhair Abdul-Jalil</style></author><author><style face="normal" font="default" size="100%">Haider Al-Wafi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">HPLC Isolation of Rutin, Hesperidin and Quercetin from Ruta Chalepensis Extract Growing in Iraq</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Ethanol</style></keyword><keyword><style  face="normal" font="default" size="100%">Extraction.</style></keyword><keyword><style  face="normal" font="default" size="100%">Maceration</style></keyword><keyword><style  face="normal" font="default" size="100%">Methanol</style></keyword><keyword><style  face="normal" font="default" size="100%">Reflex</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">606-611</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Ethnopharmacological relevance: &lt;em&gt;Ruta chalepensis &lt;/em&gt;L For years, various portions of this plant have been utilized in traditional medicine to treat a number of illnesses, including nervous disorders, rheumatism, menstrual issues, fever, convulsions, mental disorders, dropsy, and neuralgia. Objection: In this study, we aim to characterize three flavonoids extracted from &lt;em&gt;Ruta chalepensis L.&amp;nbsp;&lt;/em&gt;&lt;strong&gt;Material and Methods&lt;/strong&gt;: In this study, various concentrations (80% and 100%) of methanol and ethanol in water were used as solvents in the extraction of flavonoids (rutin, hesperidin, and quercetin) from &lt;em&gt;Ruta chalepensis &lt;/em&gt;L. by using conventional extraction methods (reflex and maceration). &lt;strong&gt;Result:&lt;/strong&gt; HPLC results confirm Using maceration with 80% methanol was recommended for extracting flavonoids from &lt;em&gt;Ruta chalepensis&lt;/em&gt; L. to obtain the highest yields, whereas reflex with 80% ethanol showed a slight increase in quercetin amount. The phytochemical screening of &lt;em&gt;Ruta chalepensis&lt;/em&gt; L. exhibited the presence of flavonoids. &lt;strong&gt;Conclusion:&lt;/strong&gt; The highest amount of the three flavonoids was found in maceration with 80% methanol.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">606</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ali Mohammed Zaki Al-Jaberi&lt;sup&gt;1&lt;/sup&gt;, Sabaa Ali Mohammed Al- Fadal&lt;sup&gt;1,*&lt;/sup&gt;, Thukaa Zuhair Abdul- Jalil&lt;sup&gt;2&lt;/sup&gt;, Haider Al-Wafi&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;University of Basra collage of pharmacy, Department of pharmacognosy, IRAQ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;University of Baghdad collage of pharmacy, Department of pharmacognosy, IRAQ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;University of Basra collage of pharmacy, Department of Clinical Laboratory Sciences, IRAQ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Shanthini Nachiar G</style></author><author><style face="normal" font="default" size="100%">Thirumal M</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">HPTLC Comparision Studies with Marker Compound and Isolation of Rutin Anti Inflammatory Agent from Ethanolic Leaf Extract of Rivea Hypocrateriformis (Desr.) Choisy</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Column chromatography</style></keyword><keyword><style  face="normal" font="default" size="100%">HPTLC studies</style></keyword><keyword><style  face="normal" font="default" size="100%">Marker compound</style></keyword><keyword><style  face="normal" font="default" size="100%">Rivea hypocrateriformis ethanolic leaf extract</style></keyword><keyword><style  face="normal" font="default" size="100%">TLC plates.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">April 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">353-358</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;To extract the leafy parts with ethanol and perform the HPTLC studies with marker compounds Quercetin, Rutin, and gallic acid then a compound was isolated and susceptible to spectroscopic analysis &lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Rivea hypocrateriformis &lt;/em&gt;(Desr.) Choisy holds Convolvulaceae family the leafy parts underwent a Soxhlet extraction with ethanol which was then subjected to a phytochemical investigation that shows the presence of alkaloids, phenols, flavonoids, terpenoids, tannins, glycosides saponins, sterols, and carbohydrates. &lt;strong&gt;Material and Methods:&lt;/strong&gt; Firstly, the ethanolic leaf extract is treated with petroleum ether to remove excess lipids, sterols, and impurities. TLC was performed by toluene: ethyl acetate: formic acid and the same solvent system was used for column chromatography. The bands getting separated into the column were collected separately in a test tube. Once the solvent toluene ends, the next solvent system with 18 ml of toluene and 2 ml of ethyl acetate, is introduced into the column, and continues the separation procedure. Collect separated bands and perform TLC of each separate band by using the same solvent system in a concentration of 5:4:1. A single component on a TLC plate with a solvent system of 12 ml toluene and 8 ml ethyl acetate was obtained whose characterization was done by IR, NMR, and mass. &lt;strong&gt;Results: &lt;/strong&gt;The RF value of Rutin is 0.17 which correlates with the Retention factor of ethanolic leaf extracts of RH by HPTLC comparative studies and a compound was isolated by column chromatography. &lt;strong&gt;Conclusion: &lt;/strong&gt;These studies have concluded that a compound is separated by means of HPTLC and spectroscopic interpretation and identified as Rutin.&lt;/p&gt;
&lt;quillbot-extension-portal&gt;&lt;/quillbot-extension-portal&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">353</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Shanthini Nachiar G, Thirumal M*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Department of Pharmacognosy, SRM College of Pharmacy, SRM Institute of science and technology, Kattankulathur, Chennai, INDIA.&lt;/p&gt;
&lt;quillbot-extension-portal&gt;&lt;/quillbot-extension-portal&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yusuf Baktir</style></author><author><style face="normal" font="default" size="100%">Muhammad Arifin Parenrengi</style></author><author><style face="normal" font="default" size="100%">Wihasto Suryaningtyas</style></author><author><style face="normal" font="default" size="100%">Dyah Fauziah</style></author><author><style face="normal" font="default" size="100%">I Ketut Sudiana</style></author><author><style face="normal" font="default" size="100%">Budi Utomo</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hydrocephalus Mice Model: Choroid Plexus Aquaporin-1 Dynamics Following Cerebrospinal Fluid Drainage</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">AQP1</style></keyword><keyword><style  face="normal" font="default" size="100%">Aquaporin 1</style></keyword><keyword><style  face="normal" font="default" size="100%">Choroid plexus</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydrocephalus.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">891-896</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Aquaporins (AQPs) are a family of membrane proteins that act as channels for water, facilitating its movement across the plasma membrane of cells. Aquaporin1 (AQP1), located in the choroid plexus, is thought to be involved in the process of cerebrospinal fluid (CSF) production. Objective: The objective of this study is to examine the impact of hydrocephalus and cerebrospinal fluid (CSF) drainage on the expression of AQP1 in a mice model of hydrocephalus.&lt;strong&gt; Material and Methods&lt;/strong&gt;: Laboratory experimental study with six groups. Five test groups, one control group, and a rat model of hydrocephalus caused by kaolin were used in the experiment. &lt;strong&gt;Results:&lt;/strong&gt; Hydrocephalus in mice model induced by kaolin, and CSF drainage was performed on the 7&lt;sup&gt;th&lt;/sup&gt; and 14&lt;sup&gt;th&lt;/sup&gt; days group. Immunohistochemical analysis was conducted to examine the presence of AQP1 in the&lt;em&gt; choroid plexus&lt;/em&gt; using microscopes. The findings revealed a noticeable decrease in AQP1 expression levels in the &lt;em&gt;choroid plexus,&lt;/em&gt; which exhibited a semi-quantitative decline in correlation with the duration of hydrocephalus (p = 0.01). This decrease was observed when comparing the normal group with the hydrocephalus groups on the 7&lt;sup&gt;th&lt;/sup&gt;, 14&lt;sup&gt;th&lt;/sup&gt;, and 21st days following induction. However, after cerebrospinal fluid (CSF) drainage, there was a significant increase in AQP1 expression (p &amp;lt; 0.05). &lt;strong&gt;Conclusions: &lt;/strong&gt;This study shows the significant role of AQP1 in CSF production by comparing of AQP1 expression in the&lt;em&gt; choroid plexus &lt;/em&gt;of hydrocephalus mice model, with and without CSF drainage. AQP1 expression experiences downregulation in hydrocephalus mice model and upregulation after CSF drainage.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">891</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Yusuf Baktir&lt;sup&gt;1&lt;/sup&gt;, Muhammad Arifin Parenrengi&lt;sup&gt;1,*&lt;/sup&gt;, Wihasto Suryaningtyas&lt;sup&gt;1&lt;/sup&gt;, Dyah Fauziah&lt;sup&gt;2&lt;/sup&gt;, I Ketut Sudiana&lt;sup&gt;2&lt;/sup&gt;, Budi Utomo&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Neurosurgery, Faculty of Medicine, Airlangga University, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pathology Anatomy, Faculty of Medicine, Airlangga University, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Public Health Science, Faculty of Medicine, Airlangga University, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">EV Ferubko</style></author><author><style face="normal" font="default" size="100%">TD Rendyuk</style></author><author><style face="normal" font="default" size="100%">TD Dargaeva</style></author><author><style face="normal" font="default" size="100%">SM Nikolaev</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Herbal Medicines Intended for Correction of Digestive System Diseases</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2022</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">128-132</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Purpose:&lt;/strong&gt; Studying the assortment of herbal medicines (HMs) available in the Russian Federation, and generalizing the use experience of them in gastroenterological practice. &lt;strong&gt;Methods:&lt;/strong&gt; Information and analytical.&lt;strong&gt; Results: &lt;/strong&gt;The analysis of the State Register of Medicines Permitted for Use in Medical Practice, as well as foreign and domestic publications from authoritative international databases, has been carried out. The limited range of drugs prescribed for diseases of the digestive system was revealed. The advantages of using complex drugs in comparison with monopreparations are shown. &lt;strong&gt;Conclusion&lt;/strong&gt;: It is necessary to develop new multicomponent HMs of high therapeutic efficacy and low toxicity for prevention and treatment of digestive system diseases.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt; Herbal medicines, Digestive system diseases, Correction.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">128</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;EV Ferubko&lt;sup&gt;1,*&lt;/sup&gt;, TD Rendyuk&lt;sup&gt;2&lt;/sup&gt;, TD Dargaeva&lt;sup&gt;1&lt;/sup&gt;, SM Nikolaev&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;All-Russian Research Institute of medicinal and Aromatic Plants, Moscow, RUSSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Sechenov First Moscow State Medical University, Moscow, RUSSIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Institute of General and Experimental Biology of the Siberian Branch of the RAS, Ulan-Ude, RUSSIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hani Plumeriastuti</style></author><author><style face="normal" font="default" size="100%">Annise Proboningrat</style></author><author><style face="normal" font="default" size="100%">Djoko Legowo</style></author><author><style face="normal" font="default" size="100%">Bilqisthi Ari Putra</style></author><author><style face="normal" font="default" size="100%">Gracia Angelina H</style></author><author><style face="normal" font="default" size="100%">Agung Budianto Achmad</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Histopathological Perspectives of Multiple Organs in a Red- Footed Tortoise (Chelonoidis carbonaria) with Suspected Metabolic Bone Disease: A Case Report</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Hematoxylin-eosin</style></keyword><keyword><style  face="normal" font="default" size="100%">MBD</style></keyword><keyword><style  face="normal" font="default" size="100%">Septicemia.</style></keyword><keyword><style  face="normal" font="default" size="100%">Tortoise</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2022</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">14</style></volume><pages><style face="normal" font="default" size="100%">1075-1078</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Introduction: Exotic pet lovers' interest in keeping tortoises is increasing all over the world, including Indonesia. However, this trend cannot be separated from the potential emergence of various health problems in tortoises. One of the problems that often affects tortoises is metabolic bone disease. Metabolic bone disease (MBD) is a disorder related to the mechanisms of vitamin D and calcium metabolism, which generally occurs in reptiles, especially Chelonia and Lizards. Case Presentation: A 3-month-old redfooted tortoise, which was clinically suspected to have a MBD, was necropsied as an effort to support the provisional diagnosis through histopathological evaluation. The purpose of this examination was to analyze the impact of the disease on various organs microscopically in patients with suspected MBD. The results showed a decrease in the number of trabeculae and hematopoietic cells in the metatarsal bones; moderate myonecrotic changes and atrophy in the skeletal muscle; inflammation of the perineuron; acute tubular necrosis and mild edema of the renal cortex; congestion and an increase in the number of melanomacrophages in the liver; as well as epicarditis and myocarditis in the heart. Conclusion: Several forms of the histopathological changes seem to indicate a pathophysiological relationship between the suspected metabolic bone disease and the multiple organs examined.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Case Report</style></work-type><section><style face="normal" font="default" size="100%">1075</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Hani Plumeriastuti&lt;sup&gt;1,*&lt;/sup&gt;, Annise Proboningrat&lt;sup&gt;1&lt;/sup&gt;, Djoko Legowo&lt;sup&gt;1&lt;/sup&gt;, Bilqisthi Ari Putra&lt;sup&gt;1&lt;/sup&gt;, Gracia Angelina Hendarti&lt;sup&gt;2&lt;/sup&gt;, Agung Budianto Achmad&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Division of Veterinary Pathology, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Division of Veterinary Anatomy, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Health, Faculty of Vocational Studies, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ruiz-Reyes SG</style></author><author><style face="normal" font="default" size="100%">Villarreal-La Torre Víctor E</style></author><author><style face="normal" font="default" size="100%">Silva-Correa Carmen R</style></author><author><style face="normal" font="default" size="100%">Sagástegui Guarniz William Antonio</style></author><author><style face="normal" font="default" size="100%">Cruzado-Razco José L</style></author><author><style face="normal" font="default" size="100%">Gamarra-Sánchez César D</style></author><author><style face="normal" font="default" size="100%">Venegas Casanova Edmundo A</style></author><author><style face="normal" font="default" size="100%">Miranda-Leyva Manuel</style></author><author><style face="normal" font="default" size="100%">Valdiviezo Campos Juan Ernesto</style></author><author><style face="normal" font="default" size="100%">Cuellar-Cuellar Armando</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective Activity of Cordia lutea Lam Flower Extracts Against Paracetamol‑Induced Hepatotoxicity in Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acetaminophen</style></keyword><keyword><style  face="normal" font="default" size="100%">Biochemical parameters</style></keyword><keyword><style  face="normal" font="default" size="100%">Cordia lutea</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatoprotection</style></keyword><keyword><style  face="normal" font="default" size="100%">Histopathology</style></keyword><keyword><style  face="normal" font="default" size="100%">Paracetamol</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">309-316</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Paracetamol or acetaminophen overdose leads to hepatotoxicity. This study evaluates the effect of &lt;em&gt;Cordia lutea&lt;/em&gt; extract on paracetamol-induced hepatotoxicity in rats. &lt;strong&gt;Methods:&lt;/strong&gt; Three different doses of dry fluid extract of &lt;em&gt;C. lutea&lt;/em&gt; (200, 400 and 600 mg / Kg) were evaluated and compared with Silymarin 200 mg / Kg. Biochemical parameters such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), direct bilirubin, indirect bilirubin, total bilirubin, albumin, globulin and total proteins were evaluated, and histopathological changes in the liver were studied and evaluated. &lt;strong&gt;Results: &lt;/strong&gt;&lt;em&gt;C. lutea &lt;/em&gt;reduced the levels of ALT, AST, ALP and increases proteins significantly, although the reduction of bilirubin was not significant, the extract at 400 mg / Kg reduced the levels better than the extract at 600 mg / Kg. The histopathological evaluation suggested that &lt;em&gt;C. lutea&lt;/em&gt; extract reduced paracetamol-induced liver necrosis. &lt;strong&gt;Conclusions: &lt;/strong&gt;The extract of &lt;em&gt;C. lutea&lt;/em&gt; has a marked hepatoprotective effect, significantly reducing the levels of ALT, AST and ALP, in addition to increasing the levels of albumin, globulin and total proteins, in&lt;em&gt; Rattus norvegicus&lt;/em&gt; var. &lt;em&gt;albinus&lt;/em&gt;.&lt;em&gt; C. lutea &lt;/em&gt;extract is an excellent candidate for use in paracetamol-induced liver diseases.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">309</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ruiz-Reyes SG, Villarreal-La Torre Víctor E*, Silva-Correa Carmen R, Sagástegui Guarniz William Antonio, Cruzado-Razco José L, Gamarra-Sánchez César D, Venegas Casanova Edmundo A, Miranda-Leyva Manuel, Valdiviezo Campos Juan Ernesto, Cuellar-Cuellar Armando&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Universidad Nacional de Trujillo, PERÚ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Raden Joko Kuncoroningrat Susilo</style></author><author><style face="normal" font="default" size="100%">Dwi Winarni</style></author><author><style face="normal" font="default" size="100%">Saikhu Akhmad Husen</style></author><author><style face="normal" font="default" size="100%">Suhailah Hayaza</style></author><author><style face="normal" font="default" size="100%">Sri Puji Astuti Wahyuningsih</style></author><author><style face="normal" font="default" size="100%">Ruey-An Doong</style></author><author><style face="normal" font="default" size="100%">Win Darmanto</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective Effect of Ganoderma applanatum Crude Polysaccharides on Carbon Tetrachloride-Induced Early Liver Fibrosis in Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-inflammatory</style></keyword><keyword><style  face="normal" font="default" size="100%">Carbon tetrachloride</style></keyword><keyword><style  face="normal" font="default" size="100%">Crude polysaccharides</style></keyword><keyword><style  face="normal" font="default" size="100%">Fibrosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Ganoderma applanatum</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1428-1436</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Liver fibrosis is a treatable disease when still at early stages. &lt;em&gt;Ganoderma applanatum &lt;/em&gt;plays role as alternative medicine. The fungi have antioxidant, anti-inflammatory, and anticancer bioactivities. This study aimed to evaluate the hepatoprotective effects of &lt;em&gt;G. applanatum &lt;/em&gt;crude polysaccharides (GACP) on liver fibrosis due to CCl4 induction. &lt;strong&gt;Methods&lt;/strong&gt;: This study was divided into six groups. BALB/c mice were given CCl4 dissolved in olive oil (2 mL/kg; 1:3) intraperitoneally (i.p) twice a week for four weeks to produce a liver fibrosis model. Distilled water (control group), silymarin 100 mg/kg and GACP 25, 50, 100 mg/kg were given once daily for four weeks. Alanine aminotransferase (ALT), aspartate aminotransferase (AST), tumor necrosis-α (TNF-α) and interleukin-6 (IL-6) were determined by enzyme-linked immunosorbent assay (ELISA) kit. Histopathology was stained by hematoxylin &amp;amp; eosin (H&amp;amp;E) and Masson’s trichome.&lt;strong&gt; Results: &lt;/strong&gt;The administration of GACP effectively prevented ALT, AST, TNF-α, and IL-6 levels from high elevation. Additionally, the GACP had protective effect after liver histological analysis exhibited less injury in the liver tissue.&lt;strong&gt; Conclusion: &lt;/strong&gt;The hepatoprotective effect of GACP on liver fibrosis is mainly due to avoid high elevation of pro-inflammatory cytokine. This result revealed that GACP could be a potential hepatoprotective agent for later clinical therapy.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1428</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Raden Joko Kuncoroningrat Susilo&lt;sup&gt;1&lt;/sup&gt;, Dwi Winarni&lt;sup&gt;1,*&lt;/sup&gt;, Saikhu Akhmad Husen&lt;sup&gt;1&lt;/sup&gt;, Suhailah Hayaza&lt;sup&gt;1&lt;/sup&gt;, Sri Puji Astuti Wahyuningsih&lt;sup&gt;1&lt;/sup&gt;, Ruey-An Doong&lt;sup&gt;1,2&lt;/sup&gt;, Win Darmanto&lt;sup&gt;1,&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biology, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Institute of Analytical and Environmental Sciences, National Tsing Hua University, Sec. 2 Kuang Fu Road, Hsinchu 30013, TAIWAN.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Suparmi Suparmi</style></author><author><style face="normal" font="default" size="100%">Minidian Fasitasari</style></author><author><style face="normal" font="default" size="100%">Martanto Martosupono</style></author><author><style face="normal" font="default" size="100%">Jubhar Christian Mangimbulude</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hypoglycemic and Antianemia Effects of Chlorophyll from Sauropus androgynus (L) Merr Leaves in Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidants</style></keyword><keyword><style  face="normal" font="default" size="100%">Chlorophyll</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetes mellitus (DM)</style></keyword><keyword><style  face="normal" font="default" size="100%">Iron deficiency anemia (IDA)</style></keyword><keyword><style  face="normal" font="default" size="100%">Sauropus androgynus (L) Merr</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">924-932</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Beneficial effect of katuk (&lt;em&gt;Sauropus androgynus &lt;/em&gt;L Merr) leaves (CSA) as one of medicinal plant in Indonesian jamu may potential to cure diabetes mellitus (DM) and iron deficiency anemia (IDA) as well as its well-known effect to increase breast milk production. &lt;strong&gt;Objectives:&lt;/strong&gt; This study was aiming to explore the hypoglycemic effects of CSA in streptozotocininduced DM rats (STZ) and antianemia effects in IDA rats (FeD). &lt;strong&gt;Material and Methods: &lt;/strong&gt;STZ male Wistar rats were treated with CSA, commercial chlorophyll (Chln) and glibencamide. Blood glucose levels and histological changes of liver, kidney and pancreas were analyzed after 14 days treatment. At separate experiment, FeD female Wistar rats were treated with CSA and Chln. The treatment was performed orally at the 1&lt;sup&gt;st&lt;/sup&gt; - 20&lt;sup&gt;th &lt;/sup&gt;day of pregnancy. Levels of Hb, Fe and ferritin blood serum, number and body weight of the offspring were analyzed on 21st day (post-partum). &lt;strong&gt;Results: &lt;/strong&gt;Treatment of CSA for 14 days to diabetic animals demonstrated the hypoglycemic effect, however the histological analysis suggested that the scores of liver, kidney and pancreas were higher than that in the normal group. Moreover, CSA exerted a significant restorative effect by returning the levels of hemoglobin, serum iron, and serum ferritin. A fetus analysis suggested that the fetus body weight of in the CSA and Chln groups was similar to that in the normal group. &lt;strong&gt;Conclusion: &lt;/strong&gt;CSA treatment are potential as a new herbal supplement to cure DM and IDA. However, the safety dose should be considered to prevent the toxicity.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">924</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Suparmi Suparmi&lt;sup&gt;1,&lt;/sup&gt;*, Minidian Fasitasari&lt;sup&gt;2,3&lt;/sup&gt;, Martanto Martosupono&lt;sup&gt;4&lt;/sup&gt;, Jubhar Christian Mangimbulude&lt;sup&gt;4&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biology, Faculty of Medicine, Universitas Islam Sultan Agung, Semarang 50112, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Clinical Nutrition, Faculty of Medicine, Universitas Islam Sultan Agung, Semarang 50112, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Sultan Agung Islamic Hospital, Semarang 50112, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Master Program of Biology, Satya Wacana Christian University, Jl. Diponegoro 52-60 Salatiga 50711, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ruqiah Ganda Putri Panjaitan</style></author><author><style face="normal" font="default" size="100%">Astrid Maulidya</style></author><author><style face="normal" font="default" size="100%">Anita Restu Puji Raharjeng</style></author><author><style face="normal" font="default" size="100%">Shovon Chakma</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Healing Capacity of Leaves Stalks Extract of Pasak Bumi (Eurycoma longifolia Jack.) on Incised Wounds of Mice Skin</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Eurycoma longifolia Jack.</style></keyword><keyword><style  face="normal" font="default" size="100%">Incised wound</style></keyword><keyword><style  face="normal" font="default" size="100%">Ointment</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1351-1356</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;&lt;em&gt;Pasak bumi &lt;/em&gt;is a medicinal plant commonly used as herbal medicine by Indonesian people. This study aims to examine the healing capacity of mice skin incised wounds by using &lt;em&gt;pasak bumi &lt;/em&gt;leaves stalks ethanol extract ointment. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;This study used twenty-five male mice Balb/ c strains, grouped into five groups, divided into three treatment groups (ointment with 20% extract concentration, ointment with 35% extract concentration, and ointment with 50% extract concentration), a positive control group using &lt;em&gt;Betadine&lt;/em&gt;®, and the negative the negative control group using an ointment base. The back of the mouse was slashed 1.0 cm long with a depth of 0.2 cm. Then, the wound was smeared twice a day for 21 consecutive days.&lt;strong&gt; Results: &lt;/strong&gt;The application of 20%, 35%, and 50% of ointment extract had the effect of healing the incised wounds after 21 days just as&lt;em&gt; Betadine&lt;sup&gt;®&lt;/sup&gt;.&lt;/em&gt; From the description score of the wound on the twenty-first day, it can be seen that the applied ointment with 35% of extract concentration shows the same healing capacity as&lt;em&gt; Betadine&lt;sup&gt;®&lt;/sup&gt;&lt;/em&gt; (p&amp;gt; 0.05), unlike the administration of ointment base (p &amp;lt;0.05). &lt;strong&gt;Conclusions:&lt;/strong&gt; It can be concluded that&lt;em&gt; pasak bumi &lt;/em&gt;leaves stalks has the potential effect to heal incised wounds.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1351</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ruqiah Ganda Putri Panjaitan&lt;sup&gt;1,&lt;/sup&gt;*, Astrid Maulidya&lt;sup&gt;1&lt;/sup&gt;, Anita Restu Puji Raharjeng&lt;sup&gt;2&lt;/sup&gt;, Shovon Chakma&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biology Education, Faculty of Teacher Training and Education, Tanjungpura University. Jl. Prof. Dr. H. Hadari Nawawi, Bansir Laut, Kec. Pontianak Tenggara, Kota Pontianak, West Kalimantan 78124, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department Biology, UIN Raden Fatah Palembang, Jl. Prof. K. H. Zainal Abidin Fikri No. 1 Kel, Pahlawan, Kec. Kemuning, Kota Palembang, South Sumatera 30126, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;School of Veterinary Science, University of Queensland, St Lucia QLD 4072, AUSTRALIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sagástegui-Guarniz William Antonio</style></author><author><style face="normal" font="default" size="100%">Silva-Correa Carmen R</style></author><author><style face="normal" font="default" size="100%">Villarreal-La Torre Víctor E</style></author><author><style face="normal" font="default" size="100%">Cruzado-Razco José L</style></author><author><style face="normal" font="default" size="100%">Calderón-Peña Abhel A</style></author><author><style face="normal" font="default" size="100%">Aspajo-Villalaz Cinthya L</style></author><author><style face="normal" font="default" size="100%">Gamarra-Sánchez César D</style></author><author><style face="normal" font="default" size="100%">Ruiz-Reyes Segundo G</style></author><author><style face="normal" font="default" size="100%">Chávez-Flores Juana E</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective and Nephroprotective Activity of Artemisia absinthium L. on Diclofenac-induced Toxicity in Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Artemisia absinthium</style></keyword><keyword><style  face="normal" font="default" size="100%">Biochemical parameters</style></keyword><keyword><style  face="normal" font="default" size="100%">Diclofenac</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatoprotective</style></keyword><keyword><style  face="normal" font="default" size="100%">Histopathology</style></keyword><keyword><style  face="normal" font="default" size="100%">Nephroprotective</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1032-1041</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Artemisia absinthium L. is known for its antimalarial activity however, hepatoprotective activity of aqueous extracts has also been reported but, nephroprotective activity not yet evaluated. &lt;strong&gt;Objective:&lt;/strong&gt; To evaluate the hepatoprotective and nephroprotective activities of &lt;em&gt;A. absinthium &lt;/em&gt;against diclofenac-induced toxicity on rats. Materials and Methods: Three different doses of methanol and ethyl acetate extract of &lt;em&gt;A. absinthium &lt;/em&gt;(50, 100 and 200 mg/kg/day) were evaluated and compared with silymarin 100 mg/kg. Rats received these doses for 5 days and on the 3rd and 4th day diclofenac (50 mg/kg i.p.) was administered 1 h after treatment. Animals were sacrificed 48 h after the last injection of diclofenac. Biochemical blood parameters like aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), urea and creatinine, and histopathologic changes of liver and kidney were studied and evaluated. &lt;strong&gt;Results:&lt;/strong&gt;&lt;strong&gt; &lt;/strong&gt;&lt;em&gt;A. absinthium &lt;/em&gt;reduced the elevated blood levels of ALT, AST, ALP, urea and creatinine with the methanol extract to 200 mg/kg/day being more effective. The histopathologic evaluation suggested that &lt;em&gt;A. absinthium &lt;/em&gt;decreased hepatic and renal necrosis induced by diclofenac. &lt;strong&gt;Conclusions: &lt;/strong&gt;Hepatoprotective and nephroprotective activities of methanol and ethyl acetate extract of &lt;em&gt;A. absinthium&lt;/em&gt; were demonstrated, being methanol extract to 200 mg/kg/day the most effective. This provides scientific support for the use of medicinal plants such as&lt;em&gt; A. absinthium &lt;/em&gt;in the treatment of liver and kidney disorders.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1032</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Sagástegui-Guarniz William Antonio&lt;sup&gt;1&lt;/sup&gt;, Silva-Correa Carmen R&lt;sup&gt;1&lt;/sup&gt;, Villarreal-La Torre Víctor E&lt;sup&gt;1,&lt;/sup&gt;*, Cruzado-Razco José L&lt;sup&gt;1&lt;/sup&gt;, Calderón- Peña Abhel A&lt;sup&gt;2&lt;/sup&gt;, Aspajo-Villalaz Cinthya L&lt;sup&gt;2&lt;/sup&gt;, Gamarra-Sánchez César D&lt;sup&gt;1&lt;/sup&gt;, Ruiz-Reyes Segundo G&lt;sup&gt;1&lt;/sup&gt;, Chávez-Flores Juana E&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Facultad de Farmacia y Bioquímica, Universidad Nacional de Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Facultad de Ciencias Biológicas, Universidad Nacional de Trujillo, PERÚ.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Facultad de Farmacia y Bioquímica, Universidad Norbert Wiener, PERÚ.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Lal Chand Pal</style></author><author><style face="normal" font="default" size="100%">Anil kumar</style></author><author><style face="normal" font="default" size="100%">Veena Pande</style></author><author><style face="normal" font="default" size="100%">Ch V Rao</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective Effect of Bioactive Fraction of Lagerstroemia speciosa (L.) Pers. Bark Against Monosodium Glutamate-Induced Liver Toxicity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Apoptosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Lagerstroemia speciosa</style></keyword><keyword><style  face="normal" font="default" size="100%">Monosodium glutamate</style></keyword><keyword><style  face="normal" font="default" size="100%">Superoxide dismutase</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1630-1640</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; The phenolics and flavanoid enriched bioactive fraction of &lt;em&gt;L. speciosa&lt;/em&gt; bark were reported for its medicinal value in various illness however hepatoprotective activity against monosodium glutamate-induced liver toxicity yet to be reported. &lt;strong&gt;Objective:&lt;/strong&gt; To evaluate the hepatoprotective and antioxidant potential of &lt;em&gt;L. speciosa&lt;/em&gt; bark extract fraction against monosodium glutamate-induced liver toxicity. &lt;strong&gt;Methods: &lt;/strong&gt;The phytochemical constituent of ethyl acetate fraction of &lt;em&gt;L. speciosa&lt;/em&gt; bark extract (LSE) were identified by GC-MS analysis. The antioxidant activity of LSE were analyzed with &lt;em&gt;in-vitro&lt;/em&gt; antioxidant assay and subjected to evaluate hepatoprotective activity against monosodium glutamate induced liver toxicity in rat. &lt;strong&gt;Results:&lt;/strong&gt; LSE evaluated as rich in phenolics and flavonoid content along with potent hepatoprotective activity. GC-MS analysis of bioactive fraction exhibits Palmitic Acid, Octadecanoic acid, 5-methyluridine, catechine, epigallocatechin, and norgestrel as major biologically active phytocompounds. Oral administration of LSE (100 and 200 mg/kg.) declined the elevated levels of the biochemical marker as well as interleukins while enhanced the enzymatic antioxidant activity and reduced the increased level of stress marker (MDA) in monosodium glutamate-induced rats. It also restored the altered expression level of proapoptotic genes, but there is no significant change in the expression level of the anti-apoptotic gene. LSE improved histopathology of the liver through the improvement of hepatocellular architecture, inflammation, and attenuation of vascular and cellular degeneration. &lt;strong&gt;Conclusion:&lt;/strong&gt; The bioactive fraction of &lt;em&gt;L. speciosa&lt;/em&gt; bark was found to exhibit strong antioxidant and hepatoprotection in monosodium glutamate induced liver toxicity in rats.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1630</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Lal Chand Pal&lt;sup&gt;1,2&lt;/sup&gt;, Anil kumar&lt;sup&gt;1,2&lt;/sup&gt;, Veena Pande&lt;sup&gt;2&lt;/sup&gt;, Ch.V. Rao&lt;sup&gt;1,&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;CSIR-National Botanical Research Institute, Lucknow, UP, INDIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biotechnology, Kumaun University, Nainital, Uttarakhand- 263001, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yudi Her Oktaviono</style></author><author><style face="normal" font="default" size="100%">Muhammad Rafdi Amadis</style></author><author><style face="normal" font="default" size="100%">Makhyan Jibril Al-Farabi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">High Dose Allicin with Vitamin C Improves EPCs Migration from the Patient with Coronary Artery Disease</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Allicin</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Endothelial Progenitor</style></keyword><keyword><style  face="normal" font="default" size="100%">Migration</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">232-235</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Endothelial Progenitor Cells (EPCs) have an important role in endothelial dysfunction repairment through neovasculogenesis and cardiac myocytes regeneration. However, EPCs migration is greatly reduced in the patient with Coronary Artery Disease (CAD). Allicin and Vitamin C are hypothesized to improve EPCs migration due to its antioxidant properties. &lt;strong&gt;Objective:&lt;/strong&gt; To investigate the effect of Allicin and its combination with Vitamin C in EPCs migration of CAD patients. &lt;strong&gt;Material and Method:&lt;/strong&gt; Mononuclear cells were isolated from CAD patients and cultured on fibronectin-coated plates with colony-forming unit Hill medium. The cells were divided into untreated (control), Allicin treatment (dose 100 mcg/ml, 200 mcg/ml, 400 mcg/ ml), and each dose of Allicin combined with 250 mcg/mL of Vitamin C. EPCs migration was assessed with Transwell Migration Assay Kit and evaluated by using statistical tests. &lt;strong&gt;Results: &lt;/strong&gt;This research shows that EPC migration was significantly higher in the treatment. Allicin at all dose (dose 100 mcg/ml, 200 mcg/ml, 400 mcg/ml) and its combination with 250 mcg/mL of vitamin C compared to untreated group (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05). Allicin increase EPCs migration in a dosedependent manner. However, the only combination of 400 mcg/ml Allicin with 250 mcg/mL of vitamin C which has significantly higher EPCs migration compared to Allicin treatment alone. &lt;strong&gt;Conclusion: &lt;/strong&gt;Allicin improves EPCs migration in a dose-dependent manner. Improvement of the migration only observed on the Allicin dose 400 mcg/ml with Vitamin C.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">232</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Yudi Her Oktaviono&lt;sup&gt;1,&lt;/sup&gt;*, Muhammad Rafdi Amadis&lt;sup&gt;1&lt;/sup&gt;, Makhyan Jibril Al-Farabi&lt;sup&gt;1,2&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Airlangga, Prof Moestopo Street 6-8, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;School of Management, Healthcare Entrepreneurship Division, University College London, Gower St, Bloomsbury, WC1E 6BT London, UK.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Yudi Her Oktaviono</style></author><author><style face="normal" font="default" size="100%">Melly Susanti</style></author><author><style face="normal" font="default" size="100%">Achmad Lefi</style></author><author><style face="normal" font="default" size="100%">Ferry Sandra</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Human Umbilical Cord Blood-derived Secretome Enhance Endothelial Progenitor Cells Migration on Hyperglycemic Conditions</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Endothelial progenitor cells</style></keyword><keyword><style  face="normal" font="default" size="100%">Hyperglycemia state</style></keyword><keyword><style  face="normal" font="default" size="100%">Mesenchymal stem cells</style></keyword><keyword><style  face="normal" font="default" size="100%">Migration</style></keyword><keyword><style  face="normal" font="default" size="100%">Secretome</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">793-797</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;Hyperglycemia state is harmful to body’s homeostasis. Uncontrolled hyperglycemic patients, especially patients with diabetes mellitus have a higher mortality risk of heart disease 2 to 4 times compared to non-hyperglycemic patients. Vascular endothelial impairment always been observed and found as a key feature of hyperglycemia state, which is correlated with reduced numbers and dysfunction of endothelial progenitor cells (EPCs). &lt;strong&gt;Objective: &lt;/strong&gt;This paper aims to investigate the effect of hUCB-MSCs derived secretome treatment on the EPCs migration under hyperglycemia state. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;EPCs were isolated and cultured from peripheral blood samples and cultured for three days. Cultured EPCs were cultivated in 6-well plates until confluence and incubated with high glucose for 5 days, then placed in the modified Boyden chamber at the upper chamber with basal media. The lower chamber was supplemented with basal media and secretome at 2%, 10%, and 20% concentration and VEGF treated group as a control. EPCS migration was evaluated using a Boyden chamber assay. Statistical analysis was performed using SPS 25.0. &lt;strong&gt;Results: &lt;/strong&gt;EPCs migration were significantly higher when hUCB-MSCs-derived secretome was given in high glucose concentrations compared to the and control group (79.80 ± 5.07 vs 51.00 ± 5.15, &lt;em&gt;p&lt;/em&gt;&amp;lt;0.000). This study also showed that hUCB-MSCs-derived secretome increase EPCs migration under high glucose concentrations in a dose-dependent manner (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05). &lt;strong&gt;Conclusion:&lt;/strong&gt; hUCB-MSCsderived secretome enhances EPCs migration under hyperglycemic state. This result may be of relevance for cell-free and regenerative therapeutic modality for a diabetic patient with coronary artery disease (CAD).&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">793</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Yudi Her Oktaviono&lt;sup&gt;1,&lt;/sup&gt;*, Melly Susanti&lt;sup&gt;1,&lt;/sup&gt;*, Achmad Lefi&lt;sup&gt;1&lt;/sup&gt;, Ferry Sandra&lt;sup&gt;2,3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Airlangga, Prof Moestopo Street 6-8, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Prodia Stem Cell Laboratory, Kramat 7 No. 11 Street, Jakarta, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biochemistry and Molecular Biology, Faculty of Dentistry, Universitas Trisakti, Kyai Tapa Street No.260, Jakarta, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ana L Agüero-Hernández</style></author><author><style face="normal" font="default" size="100%">Catalina Rosales-López</style></author><author><style face="normal" font="default" size="100%">Cristina Herrera</style></author><author><style face="normal" font="default" size="100%">Andrés Vargas-Picado</style></author><author><style face="normal" font="default" size="100%">Rodrigo Muñoz</style></author><author><style face="normal" font="default" size="100%">Ana Abdelnour-Esquivel</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hypoglycemic Effect of Kalanchoe pinnata (Lam) Pers. Leaf Extract</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antidiabetic activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Kalanchoe pinnata</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">557-561</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; &lt;em&gt;Kalanchoe pinnata &lt;/em&gt;(Lam) Pers (Crasulaceae) is a succulent ornamental plant. In Costa Rica, the leaves are used as a coadjuvant treatment for &lt;em&gt;Diabetes Mellitus&lt;/em&gt; based on traditional knowledge of natural remedies. Moreover, there are some studies mentioning its use for &lt;em&gt;Diabetes Mellitus&lt;/em&gt; as medicinal plant in several countries. This research aimed to demonstrate the antidiabetic properties of hydroalcoholic extracts of &lt;em&gt;K. pinnata&lt;/em&gt; leaves through phytochemical screening, alpha amylase inhibition and rodent models. &lt;strong&gt;Methods: &lt;/strong&gt;Crude extracts of &lt;em&gt;K. pinnata&lt;/em&gt; leaves were prepared by infusion and decoction using water:ethanol (70:30) as a solvent. The extracts prepared by decoction (LAED, lyophilized-water:ethanoldecoction) and by infusion (LAEI, lyophilized-water:ethanol-infusion) were analyzed by FolinCiocalteu, HPLC and capacity of inhibition of α-amylase activity. To determine hypoglycemic activity in rats, extracts were administered orally at doses of 250, 500 and 750 mg/Kg and blood sugar levels were monitored over a four hours period using a glucometer. &lt;strong&gt;Results:&lt;/strong&gt; A significant reduction (p &amp;lt; 0.05) in blood glucose was observed after one hour in rats treated with 500 mg/Kg of LAED extract. Treatment with 750 mg/Kg LAEI induced a statistically significant reduction in blood sugar at 90, 180 and 240 min, showing that the glucose-lowering effect of this extract was greater at a higher concentration. &lt;strong&gt;Conclusions: &lt;/strong&gt;This study confirmed the hypoglycemic effect of &lt;em&gt;K. pinnata&lt;/em&gt; extracts in the acute phase in rats and supports the use of this Crassulaceae as a home remedy.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">557</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Ana L. Agüero-Hernández&lt;sup&gt;1,&lt;/sup&gt;*, Catalina Rosales-López&lt;sup&gt;1&lt;/sup&gt;, Cristina Herrera&lt;sup&gt;2&lt;/sup&gt;, Andrés Vargas-Picado&lt;sup&gt;3&lt;/sup&gt;, Rodrigo Muñoz&lt;sup&gt;3&lt;/sup&gt;&lt;sup&gt;&amp;nbsp;&lt;/sup&gt;and Ana Abdelnour-Esquivel&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Centro de Investigación en Biotecnología (CIB), del Instituto Tecnológico de Costa Rica, Cartago, COSTA RICA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Instituto de Investigaciones Farmacéuticas (INIFAR), Facultad de Farmacia, Universidad de Costa Rica, San José, COSTA RICA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Centro Nacional de Innovaciones Biotecnológicas (CENIBiot), San José, COSTA RICA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">I Gde Rurus Suryawan</style></author><author><style face="normal" font="default" size="100%">Andrianto</style></author><author><style face="normal" font="default" size="100%">Ratna Dewi Cahyaningtias</style></author><author><style face="normal" font="default" size="100%">Makhyan Jibril Al-Farabi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hypoxic Preconditioning Decrease ROS and Increase SOD Expression in Adipose-Derived Mesenchymal Cell</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypoxia</style></keyword><keyword><style  face="normal" font="default" size="100%">Oxidative stress</style></keyword><keyword><style  face="normal" font="default" size="100%">Stem Cells</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">430-435</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Adipose-derived Mesenchymal Stem Cells (AMSCs) have promising ability to differentiate into a cardiomyocyte. However, post-transplantation survival of AMSCs is relatively low due to lethal cellular hypoxia. Hypoxic preconditioning is a sublethal hypoxia condition which may improve AMSCs survival. This research evaluates the effect of hypoxic preconditioning on the expression of reactive oxygen species (ROS) and superoxide dismutase (SOD) of AMSCs. Isolated human AMSCs was cultured to the 4&lt;sup&gt;th&lt;/sup&gt; passage and confirmed with CD45, CD90 and CD105 expression. Cells were divided into control group (normoxia with 21% O&lt;sub&gt;2&lt;/sub&gt;) and hypoxic preconditioning group (with 1% O&lt;sub&gt;2&lt;/sub&gt;). ROS and SOD were evaluated using immunofluorescence and analyzed using SPSS 25. AMSCs was characterized by the CD105 and CD90 without expression of CD44 and CD45. ROS expression is significantly lower in hypoxia group than in controlled group (253,13 ± 67,795 vs 342,13 ± 116,447; p &amp;lt; 0.05) and SOD expression is significantly higher in hypoxia group than in controlled group (340,25 ± 96,476 vs 234,56 ± 38,238; p &amp;lt;0.05). In conclusion, hypoxic preconditioning in human AMSCs induce lower expression of intracellular ROS and higher expression of intracellular SOD.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">430</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;I Gde Rurus Suryawan&lt;sup&gt;1,&lt;/sup&gt;*, Andrianto&lt;sup&gt;1&lt;/sup&gt;, Ratna Dewi Cahyaningtias&lt;sup&gt;1&lt;/sup&gt;, Makhyan Jibril Al-Farabi&lt;sup&gt;1,2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Cardiology and Vascular Medicine, Soetomo General Hospital, Airlangga University, Mayjend. Prof. Dr. Moestopo Street No.6-8, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;School of Health Management, University College London, Gower St, Bloomsbury, London WC1E 6BT, UK.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Boualem HARFI</style></author><author><style face="normal" font="default" size="100%">Lakhdar KHELIFI</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hairy Root Technology: Effect of Etiolation on Datura sp. Transgenic Root Induction and Hyoscyamine Production</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Datura sp.</style></keyword><keyword><style  face="normal" font="default" size="100%">Etiolation</style></keyword><keyword><style  face="normal" font="default" size="100%">Gas chromatography</style></keyword><keyword><style  face="normal" font="default" size="100%">Hairy roots</style></keyword><keyword><style  face="normal" font="default" size="100%">Hyoscyamine</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">991-995</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Hyoscyamine, because of its medicinal properties, is an important tropane alkaloid. In order to implement a biotechnological process for its production, hairy roots of&lt;em&gt; Datura &lt;/em&gt;species resulting from genetic transformation by &lt;em&gt;Agrobacterium rhizogenes&lt;/em&gt; A4 strain have been the subject of this work. In the &lt;em&gt;in vitro &lt;/em&gt;alkaloids production programs, optimization of the transformation is a crucial step for obtaining a large number of root lines allowing the selection of efficient lines. &lt;strong&gt;Methods:&lt;/strong&gt; The conditions for hairy roots induction were explored by studying the effect of &lt;em&gt;Datura&lt;/em&gt; sp. &lt;em&gt;in vitro&lt;/em&gt; seedling etiolation on the genetic transformation. The first step was the establishment of &lt;em&gt;Datura&lt;/em&gt; &lt;em&gt;in vitro&lt;/em&gt; plantlet cultures followed by the hairy roots induction with A4 strain of &lt;em&gt;A. rhizogenes&lt;/em&gt;. The confirmation of the genetic transformation was performed by polymerase chain reaction (PCR) analysis of rolB gene in the roots. After hyoscyamine extraction, it was analyzed (quantitatively and qualitatively) by gas chromatography. Results: 343 root lines were obtained in total, 96 root lines from non-etiolated &lt;em&gt;Datura in vitro&lt;/em&gt; seedlings and 247 root lines from etiolated &lt;em&gt;in vitro&lt;/em&gt; plantlets. After the selection of six transgenic root lines, tow root lines from each species (&lt;em&gt;D. tramonium, D. tatula &lt;/em&gt;and&lt;em&gt; D. innoxia&lt;/em&gt;), one from non-etiolated &lt;em&gt;in vitro &lt;/em&gt;plantlet and one from etiolated &lt;em&gt;in vitro&lt;/em&gt; plantlet, the most hyoscyamine content was 8.43 mg/g D.W. obtained with &lt;em&gt;D. tatula&lt;/em&gt; etiolated &lt;em&gt;in vitro&lt;/em&gt; seedling. &lt;strong&gt;Conclusion: &lt;/strong&gt;The etiolated&lt;em&gt; in vitro&lt;/em&gt; plantlets seem more favorable to hairy roots induction.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">991</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Boualem HARFI&lt;sup&gt;1,2,&lt;/sup&gt;*, Lakhdar KHELIFI&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Biotechnology Research Center (C.R.Bt), Constantine, ALGERIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;National Higher School of Agronomy (ENSA – El-Harrach), Algiers, ALGERIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rezi Riadhi Syahdi</style></author><author><style face="normal" font="default" size="100%">Jasmine Tiara Iqbal</style></author><author><style face="normal" font="default" size="100%">Abdul Munim</style></author><author><style face="normal" font="default" size="100%">Arry Yanuar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">HerbalDB 2.0: Optimization of Construction of Three-Dimensional Chemical Compound Structures to Update Indonesian Medicinal Plant Database</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Herbal database</style></keyword><keyword><style  face="normal" font="default" size="100%">MarvinSketch</style></keyword><keyword><style  face="normal" font="default" size="100%">Three-dimensional structure</style></keyword><keyword><style  face="normal" font="default" size="100%">VegaZZ</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1189-1194</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Objective: &lt;/strong&gt;Development of novel drugs is an important challenge in the pharmaceutical world and industry. &lt;em&gt;In-silico &lt;/em&gt;methods are often considered in refinement / correction processes of drug design because they may lower the costs. The &lt;em&gt;in-silico&lt;/em&gt; drug discovery process requires a three- Dimensional Structure (3DS) of the chemical compounds as input. Computational 3DSs often exhibit structural mismatches thus affecting the validity of the &lt;em&gt;in-silico&lt;/em&gt; drug design process. In a previous study, a 3DS database with 1405 of Indonesian herbal compounds was developed, named HerbalDB. In this database, various structural mismatches were identified in some of the 3DSs. Our study aimed to identify and correct the structural mismatches in the herbalDB and to determine the best method in creating correct 3DS of chemical compounds. &lt;strong&gt;Methods: &lt;/strong&gt;Structural mismatches in the herbal database were identified by molecular visualization. &lt;strong&gt;Results:&lt;/strong&gt; The identification process yielded 170 compounds with structural mismatches that were corrected with 10 different parameters using the MarvinSketch and VegaZZ software, evaluated by molecular visualization. &lt;strong&gt;Conclusions:&lt;/strong&gt; based on 3DS of chemical compound visualization, *.mol and *.sdf file format created using Dreiding force fields of MarvinSketch are the best method to construct the proper structure of Indonesian medicinal plant’s chemical compound database compared with MMFF94, AMBER and CHARMM forcefields.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">1189</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Rezi Riadhi Syahdi&lt;sup&gt;1&lt;/sup&gt;, Jasmine Tiara Iqbal&lt;sup&gt;1&lt;/sup&gt;, Abdul Munim&lt;sup&gt;1&lt;/sup&gt;, Arry Yanuar&lt;sup&gt;1&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Pharmacy, Universitas Indonesia, Depok, 16424 West Java, INDONESIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gan B Bajracharya</style></author><author><style face="normal" font="default" size="100%">Pratigya KC</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">A High Antibacterial Efficacy of Fruits of Litsea cubeba (Lour.) Pers from Nepal. GC-MS and Antioxidative Capacity Analyses</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Brine-shrimp assay</style></keyword><keyword><style  face="normal" font="default" size="100%">DPPH assay</style></keyword><keyword><style  face="normal" font="default" size="100%">GC-MS analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Litsea oil</style></keyword><keyword><style  face="normal" font="default" size="100%">Minimum bactericidal concentration</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">889-893</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Biological activities of the plant materials may vary with different geographic origin. &lt;em&gt;Litsea cubeba &lt;/em&gt;fruits are consumed in Nepal as a spice ingredient and are considered to be possessed antibacterial property. &lt;strong&gt;Objectives:&lt;/strong&gt; Aims of this work are: to compare phytoconstituents present in litsea oil by GC-MS analysis, and to evaluate antibacterial and antioxidant activities of the volatile oil and the fruit extracts. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;Hydrodistillation of &lt;em&gt;L. cubeba&lt;/em&gt; fruits was performed to obtain litsea oil followed by extractions with boiling methanol. Fractionations of the extract provided hexane, dichloromethane, ethyl acetate and aqueous extracts. The oil and extracts were analysed for the phytochemicals present. They were evaluated by using antibacterial susceptibility, brine-shrimp lethality and antioxidant capacity assays. &lt;strong&gt;Results:&lt;/strong&gt; All together 49 compounds (accounting 93.66%) were identified in the litsea oil by GC-MS. Monoterpenes being dominant components, the oil constituted 15.96% of citral (geranial and neral). Other major constituents were capric acid (12.44%), β-caryophyllene oxide (7.69%), linalool (5.96%), eucalyptol (5.13%) and cis- β-terpineol (4.22%). Litsea oil, hexane extract and dichloromethane extract displayed very effective antibacterial property. Ethyl acetate extract (LC&lt;sub&gt;50&lt;/sub&gt; = 21.52 μg mL‒1) and litsea oil (LC&lt;sub&gt;50&lt;/sub&gt; = 31.62 μg mL‒1) were found highly cytotoxic against brine-shrimp nauplii. Ethyl acetate (IC&lt;sub&gt;50&lt;/sub&gt; = 124.57 μg mL‒1) and dichloromethane (IC&lt;sub&gt;50&lt;/sub&gt; = 271.08 μg mL‒1) extracts displayed a modest DPPH free radical scavenging activity. &lt;strong&gt;Conclusion:&lt;/strong&gt; Phytoconstituents present in the &lt;em&gt;L. cubeba&lt;/em&gt; fruits from Nepal were analysed. Litsea oil and the extracts have displayed high antibacterial and potentially anticarcinogenic activities.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">889</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Gan B Bajracharya&lt;sup&gt;1,&lt;/sup&gt;*, Pratigya KC&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Faculty of Science, Nepal Academy of Science and Technology (NAST), Khumaltar, Lalitpur, NEPAL.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Chemistry, Tri-Chandra Multiple Campus, Tribhuvan University, Kathmandu, NEPAL.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Worawat Songjang</style></author><author><style face="normal" font="default" size="100%">Arunya Jiraviriyakul</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Honokiol and Magnolol Induce Apoptosis and Cell Cycle Arrest in Human Ovarian Cancer Cells</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Apoptosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Honokiol</style></keyword><keyword><style  face="normal" font="default" size="100%">Magnolol</style></keyword><keyword><style  face="normal" font="default" size="100%">Metastasis</style></keyword><keyword><style  face="normal" font="default" size="100%">Ovarian Cancer</style></keyword><keyword><style  face="normal" font="default" size="100%">Proliferation</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">1114-1123</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Ovarian cancer is a major cause of cancer-related death among women. The growth, persistence, and cancer metastasis are causes of poor prognosis and high mortality rate. Honokiol and magnolol are derivative compounds extracted from the root and stem bark of &lt;em&gt;Magnolia officinalis&lt;/em&gt;. Many studies have reported that honokiol and magnolol have anti-tumour effects on various types of cancer. The present study investigates the anti-tumour effect of these compounds on human ovarian cancer. &lt;strong&gt;Methods:&lt;/strong&gt; Ovarian cancer cell lines, SKOV3 and ES-2 cells were tested with honokiol and magnolol to determine their responses including the cytotoxicity, cell proliferation, induction of cell apoptosis and metastasis ability. &lt;strong&gt;Result:&lt;/strong&gt; The results indicate that low concentrations of honokiol and magnolol suppressed the proliferation of ovarian cancer cells through induction of cell cycle arrest at G0/G1 and down-regulation of the cyclin D1 protein. These compounds also exhibited an anti-metastatic ability mediated by inhibiting migration, adhesion, and MMP activities. Additionally, high concentrations of honokiol and magnolol could activate cell death associated with the apoptosis signalling pathway, either along an intrinsic or extrinsic pathway. &lt;strong&gt;Conclusion: &lt;/strong&gt;The data provides evidence that honokiol and magnolol have potential anti-tumour properties and minimal toxicity on normal cells, and could therefore be applied in the treatment of ovarian cancer.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1114</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Worawat Songjang&lt;sup&gt;1&lt;/sup&gt; and Arunya Jiraviriyakul&lt;sup&gt;2&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Biomedical Science Graduated School, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok 65000, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Medical technology, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok 65000, THAILAND.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Fidan Suleymanova</style></author><author><style face="normal" font="default" size="100%">Olga Nesterova</style></author><author><style face="normal" font="default" size="100%">Alexey Matyushin</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">HPLC Quantification of Hydroxycinnamic and Organic Acids of Canadian Goldenrod (Solidago canadensis L.)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Canadian goldenrod</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Hydroxycinnamic acids</style></keyword><keyword><style  face="normal" font="default" size="100%">Organic acids</style></keyword><keyword><style  face="normal" font="default" size="100%">Solidago canadensis</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2019</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2019</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">11</style></volume><pages><style face="normal" font="default" size="100%">400-404</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;strong&gt;Background&lt;/strong&gt;: Canadian goldenrod (&lt;em&gt;Solidago canadensis&lt;/em&gt; L.) is a medicinal plant widely used in traditional medicine across the world for several hundred years. According to literature data, &lt;em&gt;S. canadensis&lt;/em&gt; contains various groups of biologically active substances, including tannins, flavonoids, etc. The aim of the study was to identify and quantify hydroxycinnamic and organic acids in aerial parts of Canadian goldenrod, as these groups of substances demonstrate a broad spectrum of therapeutic activities. &lt;strong&gt;Materials and Methods&lt;/strong&gt;: Ethanolic extracts of &lt;em&gt;S. canadensis&lt;/em&gt;, gathered in Central Russia, were analyzed using highperformance liquid chromatography (HPLC). Hydroxycinnamic acids (HCA) determination was carried out by HPLC method with UV detection at 330 nm using HCA reference standards (RS). Organic acids (OA) determination was performed in the same manner, utilizing UV detection at 210 nm and corresponding OA RS. &lt;strong&gt;Results&lt;/strong&gt;: It was established that &lt;em&gt;S. canadensis&lt;/em&gt; HCA composition is represented by cichoric, caffeic, chlorogenic, quinic and ferulic acids. The total HCA content in was 1.16 g ± 10.7 mg / 100 g. Main OA, found in &lt;em&gt;S. canadensis&lt;/em&gt;, are ascorbic, citric, tartaric, succinic, gallic, malic, oxalic and fumaric acids, with the total OA content of 426.5 mg ± 6.4 mg / 100 g. &lt;strong&gt;Conclusion&lt;/strong&gt;: The described HPLC method was successfully used for analysis of &lt;em&gt;S. canadensis&lt;/em&gt; aerial parts ethanolic extracts. The method can be utilized for HCA and OA identification and quantification in both herbal raw material and herbal medicinal products containing Canadian goldenrod.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">400</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;!-- x-tinymce/html --&gt;&lt;/p&gt;

&lt;p&gt;&lt;strong&gt;Fidan Suleymanova&lt;sup&gt;1,&lt;/sup&gt;*, Olga Nesterova&lt;sup&gt;1&lt;/sup&gt;, Alexey Matyushin&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Chemistry, Institute of Pharmacy, Sechenov First Moscow State Medical University, 119991 Moscow, RUSSIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Analytical Toxicology, Pharmaceutical Chemistry and Pharmacognosy, Institute of Pharmacy, Sechenov First Moscow State Medical University, 119991 Moscow, RUSSIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ramesh Kumar Gupta</style></author><author><style face="normal" font="default" size="100%">Sudhansu Ranjan Swain</style></author><author><style face="normal" font="default" size="100%">Jagannath Sahoo</style></author><author><style face="normal" font="default" size="100%">Amresh Gupta</style></author><author><style face="normal" font="default" size="100%">Sachin Chaudhary</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective Potential of Trichosanthes dioica Roxb in Hepatotoxicity Induced by Simvastatin and its consequences on Biochemical and Haematological Indices</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Hepatocytes</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Liver</style></keyword><keyword><style  face="normal" font="default" size="100%">Simvastatin</style></keyword><keyword><style  face="normal" font="default" size="100%">Trichosanthes dioica</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/658</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">720-724</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt;To evaluate hepatoprotective activity along with hematological and defensive recital of &lt;em&gt;Trichosanthes dioica&lt;/em&gt; Roxb against simvastatin induced hepatotoxicity in experimental rodents. &lt;strong&gt;Methods:&lt;/strong&gt; In the present study, &lt;em&gt;in- vivo&lt;/em&gt; hepatoprotective effect of 50% methanolic fruit extract of &lt;em&gt;Trichosanthes dioica&lt;/em&gt; Roxb (TME 200 and 400 mg/kg body weight) was evaluated using experimental model, simvastatin (20 mg/kg, &lt;em&gt;p.o&lt;/em&gt;.), induced hepatotoxicity in experimental animals. The hepatoprotective activity was estimatedby interpreting using various biochemical parameters like SGOT, SGPT, ALP, total bilirubin, total protein and albumin along with the haematological and histopathological studies. &lt;strong&gt;Results:&lt;/strong&gt; The treatment with TME significantly (P&amp;lt;0.05-P&amp;lt;0.001) and dose-dependently reversed simvastatin induced elevation in serum level ofSGOT, SGPT, ALP, total bilirubin and restored the total protein and albumin level. Furthermore, TME also signify the blood parameters at dose of 1000 and 2000 mg/kg and restored the body defense mechanism. The histological examination revealed that TME at dose of 200 mg/kg showed regeneration of hepatocytes around central vein with near normal liver architecture. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results of this study exhibited liver protective effect of &lt;em&gt;Trichosanthes dioica&lt;/em&gt; Roxb against simvastatin induced liver injury and there by scientifically support its traditional use.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">720</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ramesh Kumar Gupta&lt;sup&gt;1,2*&lt;/sup&gt;, Sudhansu Ranjan Swain&lt;sup&gt;3&lt;/sup&gt;, Jagannath Sahoo&lt;sup&gt;4&lt;/sup&gt;, Amresh Gupta&lt;sup&gt;5&lt;/sup&gt;, Sachin Chaudhary&lt;sup&gt;6&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Sherwood College of Faculty of Pharmacy, Barabanki -225001, Uttar Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;S.R.M.S. College of Engineering and Technology, Bareilly-243202, Uttar Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Moradabad Educational Trust Group of Institutions, Faculty of Pharmacy, Moradabad- 244001, Uttar Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;KIET School of Pharmacy, Ghaziabad- 201001, Uttar Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;5&lt;/sup&gt;Goel Institute of Pharmacy and Sciences, Lucknow-226024, Uttar Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;6&lt;/sup&gt;College of Pharmacy, University of Sharjah, Sharjah-27272, UNITED ARAB EMIRATES.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Parichat Phalanisong</style></author><author><style face="normal" font="default" size="100%">Kanit Vichitphan</style></author><author><style face="normal" font="default" size="100%">Jaehong Han</style></author><author><style face="normal" font="default" size="100%">Sukanda Vichitphan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">High Antioxidant and Phenolic Contents Related to Antibacterial Activity against Gastrointestinal Pathogenic Bacteria of Some Thai Medicinal Plants</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antibacterial activity</style></keyword><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Caesalpinia sappan</style></keyword><keyword><style  face="normal" font="default" size="100%">Scanning electron microscope</style></keyword><keyword><style  face="normal" font="default" size="100%">total phenolic content</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">January 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/488</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">341-348</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; Thai medicinal plants were used as the traditional medicines and as part of everyday plants diet. Plants contain a mixture of phytochemical and exhibit a lot of functional food and medicinal properties. This project aims to investigate the potential of selected Thai medicinal plants according to the properties of their antioxidant and antibacterial activities. &lt;strong&gt;Methods:&lt;/strong&gt; The eighteen plants were extracted using maceration method with 95% ethanol. The antioxidant activity was evaluated by DPPH and FRAP assay. The total phenolic content was evaluated by Folin-Ciocalteu phenol reagent. The antibacterial activity was evaluated by agar disc diffusion method. The extract which exhibited high antioxidant and antibacterial activity was selected to observe morphological changes by the scanning electron microscope (SEM). &lt;strong&gt;Results:&lt;/strong&gt; The extract of &lt;em&gt;Caesalpinia sappan&lt;/em&gt; showed the highest activities on both antioxidant assayed by FRAP method and total phenolic contents, however, exhibited high antioxidant assayed by DPPH compared to &lt;em&gt;Bauhinia strychnifolia&lt;/em&gt; extract. Moreover, the extract of &lt;em&gt;C. sappan&lt;/em&gt; showed the excellent antibacterial activities against six pathogenic bacteria in Gastro-intestinal tract. The morphological change by SEM was selected for further investigation antibacterial activities of &lt;em&gt;C. sappan&lt;/em&gt; extract. The results showed that the inhibitory effect to those bacterial strains could be caused by the disruption of the cell membrane and decrease biofilm formation after treatment with the extract. &lt;strong&gt;Conclusion:&lt;/strong&gt; The ethanol extract of &lt;em&gt;C. sappan&lt;/em&gt; exhibited strong antioxidant and antibacterial activities against the six pathogenic bacteria. This result suggested that &lt;em&gt;C. sappan&lt;/em&gt; could be applied to use for medicinal purpose and functional products.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">341</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Parichat Phalanisong&lt;sup&gt;1,2,&lt;/sup&gt; Kanit Vichitphan&lt;sup&gt;2,3&lt;/sup&gt;*, Jaehong Han&lt;sup&gt;4&lt;/sup&gt;, Sukanda Vichitphan&lt;sup&gt;2,3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Graduate School, Khon Kaen University, Khon Kaen, THAILAND.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biotechnology, Faculty of Technology, Khon Kaen University, Khon Kaen, THAILAND.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Fermentation Research Center for Value Added Agricultural Products (FerVAAP), Khon Kaen University, Khon Kaen, THAILAND.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;4&lt;/sup&gt;Department of Integrative Plant Science, Chung-Ang University, Anseong, KOREA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ashwani Kumar Bhardwaj</style></author><author><style face="normal" font="default" size="100%">Avilekh Naryal</style></author><author><style face="normal" font="default" size="100%">Pushpender Bhardwaj</style></author><author><style face="normal" font="default" size="100%">Ashish Rambhau Warghat</style></author><author><style face="normal" font="default" size="100%">Balpreet Arora</style></author><author><style face="normal" font="default" size="100%">Shikha Dhiman</style></author><author><style face="normal" font="default" size="100%">Shweta Saxena</style></author><author><style face="normal" font="default" size="100%">Pratap Kumar Pati</style></author><author><style face="normal" font="default" size="100%">Om Prakash Chaurasia</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">High Efficiency in vitro Plant Regeneration and Secondary Metabolite Quantification from Leaf Explants of Rhodiola imbricata</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acclimatization</style></keyword><keyword><style  face="normal" font="default" size="100%">Cinnamyl alcohol.</style></keyword><keyword><style  face="normal" font="default" size="100%">Endangered</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant growth regulator</style></keyword><keyword><style  face="normal" font="default" size="100%">Regeneration system</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">x</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">x</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Aim:&lt;/strong&gt; &lt;em&gt;Rhodiola imbricata&lt;/em&gt; is an endangered medicinal plant of the trans-Himalayan Leh-Ladakh region belonging to the family Crassulaceae. An efficient propagation and regeneration system via direct shoot organogenesis from leaf explant and evaluation of cinnamyl alcohol (Secondary metabolite) was established in this study. &lt;strong&gt;Material and Methods:&lt;/strong&gt; &lt;em&gt;In vitro&lt;/em&gt; grown leaves were inoculated using Murashige and Skoog (MS) medium supplemented with (alpha)- naphtalene acetic acid (NAA) in combination with 6- benzyladenine (BAP) for callus proliferation and regeneration. &lt;strong&gt;Results:&lt;/strong&gt; The highest percentage of rhizogenous callus was induced in medium containing NAA (10.0-15.0 &lt;em&gt;&amp;mu;&lt;/em&gt;M). The highest percentage of shoot formation from leaf derived callus was obtained in the medium containing of NAA (5.0 &lt;em&gt;&amp;mu;&lt;/em&gt;M) and BAP (2.5 &lt;em&gt;&amp;mu;&lt;/em&gt;M) as well as in NAA (1.0 &lt;em&gt;&amp;mu;&lt;/em&gt;M), BAP (5.0 &lt;em&gt;&amp;mu;&lt;/em&gt;M) (38.88% and 37.49%) respectively. Rooting of regenerated shoots were effective when a lower concentration of NAA (0.5 &lt;em&gt;&amp;mu;&lt;/em&gt;M) was used alone. A maximum number of roots (22.0) and higher length (0.6 cm) was observed. The &lt;em&gt;in-vitro&lt;/em&gt; plantlets with well-developed shoots and roots were acclimatized successfully to natural field conditions with a survival rate of over 80%. Cinnamyl alcohol (Secondary metabolite) evaluation was also done for the very first time and an upregulation of 49.6% and 30.6% were observed in &lt;em&gt;in-vitro&lt;/em&gt; roots and shoots when compared with mother root and shoot respectively. Hence, it was proved that the content of secondary metabolites obtained from &lt;em&gt;in-vitro&lt;/em&gt; raised plants is higher than mother plant. &lt;strong&gt;Conclusion:&lt;/strong&gt; These results may lay a foundation for genetic improvement and can be used to determine sequential level of targeted secondary metabolites through cell culture in &lt;em&gt;Rhodiola imbricata&lt;/em&gt;.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt; Regeneration system, Acclimatization, Endangered, Plant growth regulator, Cinnamyl alcohol.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2s</style></issue><work-type><style face="normal" font="default" size="100%">x</style></work-type><section><style face="normal" font="default" size="100%">XX</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ashwani Kumar Bhardwaj&lt;sup&gt;1&lt;/sup&gt;, Avilekh Naryal&lt;sup&gt;1&lt;/sup&gt;, Pushpender Bhardwaj&lt;sup&gt;1&lt;/sup&gt;, Ashish Rambhau Warghat&lt;sup&gt;1,3&lt;/sup&gt;, Balpreet Arora&lt;sup&gt;2&lt;/sup&gt;, Shikha Dhiman&lt;sup&gt;1&lt;/sup&gt;, Shweta Saxena&lt;sup&gt;1&lt;/sup&gt;, Pratap Kumar Pati&lt;sup&gt;2&lt;/sup&gt;, Om Prakash Chaurasia&lt;sup&gt;1* &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biotechnology, Defence Institute of High Altitude Research, Defence Research and Development Organization, Leh-194101, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biotechnology, Guru Nank Dev University, Amritsar-143040, Punjab, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;&lt;span style=&quot;text-decoration: line-through;&quot;&gt;3&lt;/span&gt;&lt;/sup&gt;Department of Biotechnology, Institute of Himalayan Bioresource Technology, Council of Scientific and Industrial Research, Palampur-176061, Himachal Pradesh, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ashwani Kumar Bhardwaj</style></author><author><style face="normal" font="default" size="100%">Avilekh Naryal</style></author><author><style face="normal" font="default" size="100%">Pushpender Bhardwaj</style></author><author><style face="normal" font="default" size="100%">Ashish Rambhau Warghat</style></author><author><style face="normal" font="default" size="100%">Balpreet Arora</style></author><author><style face="normal" font="default" size="100%">Shikha Dhiman</style></author><author><style face="normal" font="default" size="100%">Shweta Saxena</style></author><author><style face="normal" font="default" size="100%">Pratap Kumar Pati</style></author><author><style face="normal" font="default" size="100%">Om Prakash Chaurasia</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">High Efficiency in vitro Plant Regeneration and Secondary Metabolite Quantification from Leaf Explants of Rhodiola imbricata</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acclimatization</style></keyword><keyword><style  face="normal" font="default" size="100%">Cinnamyl alcohol</style></keyword><keyword><style  face="normal" font="default" size="100%">Endangered</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant growth regulator</style></keyword><keyword><style  face="normal" font="default" size="100%">Regeneration system</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/510</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">470-475</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Aim:&lt;/strong&gt; &lt;em&gt;Rhodiola imbricata&lt;/em&gt; is an endangered medicinal plant of the trans-Himalayan Leh-Ladakh region belonging to the family Crassulaceae. An efficient propagation and regeneration system via direct shoot organogenesis from leaf explant and evaluation of cinnamyl alcohol (Secondary metabolite) was established in this study. &lt;strong&gt;Material and Methods:&lt;/strong&gt; &lt;em&gt;In vitro&lt;/em&gt; grown leaves were inoculated using Murashige and Skoog (MS) medium supplemented with (alpha)- naphtalene acetic acid (NAA) in combination with 6- benzyladenine (BAP) for callus proliferation and regeneration. &lt;strong&gt;Results:&lt;/strong&gt; The highest percentage of rhizogenous callus was induced in medium containing NAA (10.0-15.0 &lt;em&gt;&amp;mu;&lt;/em&gt;M). The highest percentage of shoot formation from leaf derived callus was obtained in the medium containing of NAA (5.0 &lt;em&gt;&amp;mu;&lt;/em&gt;M) and BAP (2.5 &lt;em&gt;&amp;mu;&lt;/em&gt;M) as well as in NAA (1.0 &amp;mu;M), BAP (5.0 &lt;em&gt;&amp;mu;&lt;/em&gt;M) (38.88% and 37.49%) respectively. Rooting of regenerated shoots were effective when a lower concentration of NAA (0.5 &lt;em&gt;&amp;mu;&lt;/em&gt;M) was used alone. A maximum number of roots (22.0) and higher length (0.6 cm) was observed. The &lt;em&gt;in-vitro&lt;/em&gt; plantlets with well-developed shoots and roots were acclimatized successfully to natural field conditions with a survival rate of over 80%. Cinnamyl alcohol (Secondary metabolite) evaluation was also done for the very first time and an upregulation of 49.6% and 30.6% were observed in in-vitro roots and shoots when compared with mother root and shoot respectively. Hence, it was proved that the content of secondary metabolites obtained from &lt;em&gt;in-vitro&lt;/em&gt; raised plants is higher than mother plant. &lt;strong&gt;Conclusion:&lt;/strong&gt; These results may lay a foundation for genetic improvement and can be used to determine sequential level of targeted secondary metabolites through cell culture in &lt;em&gt;Rhodiola imbricata&lt;/em&gt;.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">470</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ashwani Kumar Bhardwaj&lt;sup&gt;1&lt;/sup&gt;, Avilekh Naryal&lt;sup&gt;1&lt;/sup&gt;, Pushpender Bhardwaj&lt;sup&gt;1&lt;/sup&gt;, Ashish Rambhau Warghat&lt;sup&gt;1,3&lt;/sup&gt;, Balpreet Arora&lt;sup&gt;2&lt;/sup&gt;, Shikha Dhiman&lt;sup&gt;1&lt;/sup&gt;, Shweta Saxena&lt;sup&gt;1&lt;/sup&gt;, Pratap Kumar Pati&lt;sup&gt;2&lt;/sup&gt;, Om Prakash Chaurasia&lt;sup&gt;1*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biotechnology, Defence Institute of High Altitude Research, Defence Research and Development Organization, Leh-194101, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Biotechnology, Guru Nank Dev University, Amritsar-143040, Punjab, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Biotechnology, Institute of Himalayan Bioresource Technology, Council of Scientific and Industrial Research, Palampur-176061, Himachal Pradesh, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Abhishek Gupta</style></author><author><style face="normal" font="default" size="100%">Harinath Dwivedi</style></author><author><style face="normal" font="default" size="100%">AKS Rawat</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">High Performance Thin Layer Chromatographic Analysis for the Simultaneous Quantification of Two Polyphenolic Biomarkers in Methanolic Fraction of Bauhinia tomentosa L. Floral Buds</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Bauhinia tomentosa</style></keyword><keyword><style  face="normal" font="default" size="100%">Caffeic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">HPTLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Quercetin</style></keyword><keyword><style  face="normal" font="default" size="100%">Validation</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/668</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">773-777</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objectives:&lt;/strong&gt; A high-performance thin layer chromatography (HPTLC) method for the simultaneous quantitative determination of caffeic acid and quercetin in methanolic fraction of &lt;em&gt;Bauhinia tomentosa&lt;/em&gt; L. floral buds was developed for the first time. &lt;strong&gt;Method:&lt;/strong&gt; For achieving good separation, a mobile phase of toluene: ethyl acetate: formic acid (7:3:0.5, v/v/v) was used. The densitometric determination was carried out at 366 nm in reflection/absorption mode. The calibration curves were linear in the range of 100-600 ng per spot for caffeic acid and quercetin. &lt;strong&gt;Results:&lt;/strong&gt; During the analysis methanolic fraction of &lt;em&gt;Bauhinia tomentosa&lt;/em&gt; L. floral buds showed the pres&amp;not;ence of caffeic acid (0.02%) and quercetin (0.018%). &lt;strong&gt;Conclusion:&lt;/strong&gt; The proposed method is simple, precise, specific, accurate, less time consuming and cost effective. The statistical analysis of data obtained proves that the method is reproducible and selective and can be used for routine analysis of reported phenolic compounds in crude drug and extracts. The simultaneous quan&amp;not;tification of these compounds has not yet been reported in floral buds of &lt;em&gt;Bauhinia tomentosa&lt;/em&gt; which may be utilized for the proper standardization of the plant.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">773</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Abhishek Gupta&lt;sup&gt;1,2&lt;/sup&gt;, Harinath Dwivedi&lt;sup&gt;2&lt;/sup&gt;, AKS Rawat&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;1*&lt;/strong&gt; &lt;/sup&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Pharmacognosy and Ethnopharmacology Division, CSIR-National Botanical Research Institute, Lucknow, Uttar Pradesh, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;School of Pharmacy, Babu Banarsi Das University, Faizabad Road, Lucknow, Uttar Pradesh, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Herra Williany Monalissa</style></author><author><style face="normal" font="default" size="100%">Berna Elya</style></author><author><style face="normal" font="default" size="100%">Nuraini Puspitasari</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">HMG-CoA Reductase Inhibitory Activity of Garcinia latissima Miq. Mesocarp Water Extract for Herbal Tea</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti Cholesterol</style></keyword><keyword><style  face="normal" font="default" size="100%">Garcinia Latissima</style></keyword><keyword><style  face="normal" font="default" size="100%">Herbal Tea</style></keyword><keyword><style  face="normal" font="default" size="100%">HMG-CoA reductase</style></keyword><keyword><style  face="normal" font="default" size="100%">Mesocarp</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2018</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">s141-s146</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Context:&lt;/strong&gt; High cholesterol in the blood is a risk factor for atherosclerosis that causes various diseases. The main pharmacologic intervention to reduce cholesterol levels is inhibiting the HMG-CoA reductase enzyme. One of the genera of Garcinia, &lt;em&gt;Garcinia dulcis&lt;/em&gt;, has potential as an anti-cholesterol. Based on chemotaxonomy, &lt;em&gt;Garcinia latissima&lt;/em&gt; Miq. is also estimated to have a potency as anti-cholesterol.&lt;strong&gt; Aims:&lt;/strong&gt; This study aims to test the inhibition of HMG-CoA reductase water extract activity of&lt;em&gt; G. latissima&lt;/em&gt; fruit flesh with different duration of infusions.&lt;strong&gt; Materials and Methods:&lt;/strong&gt; &lt;em&gt;Garcinia latissima&lt;/em&gt; Miq. mesocarp was extracted using infusion method with different duration of infusions. Each of extracts was tested the inhibitory activity of HMG-CoA reductase as well as the determination of total flavonoid and total phenol content. In addition, the simplicia of the mesocarp of G.latissima Miq. will be made as a herbal tea and a hedonic test is performed to find out the degree of liking for the tea. &lt;strong&gt;Result:&lt;/strong&gt; The test results showed the inhibitory activity of 100 ppm &lt;em&gt;G. latissima&lt;/em&gt; Miq. mesocarp water extract with infusion for 5, 10 and 15 min respectively 11.32; 29.02; 13.03%. The 10 min extract with the largest enzyme inhibition had total flavonoids content of 31.24 mg QE / gram extract and total phenol content of 4.64 mg GAE/ gram extract. The result of the hedonic test for the colour, aroma, flavour of herbal tea formula A respectively 30; 30; 20% and formula B respectively for 40; 33.3; 50%. Conclusion: The water extract of G.latissima Miq mesocarp has a low potency in HMG-CoA reductase inhibitory activities.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s141</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Herra Williany Monalissa, Berna Elya&lt;sup&gt;*&lt;/sup&gt;, Nuraini Puspitasari &lt;/strong&gt;&lt;/p&gt;
&lt;p&gt;Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Universitas Indonesia Depok, 16424, West Java, INDONESIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Parameswari Royapuram Parthasarathy</style></author><author><style face="normal" font="default" size="100%">Janani Murthy</style></author><author><style face="normal" font="default" size="100%">Dinesh Murugan Girija</style></author><author><style face="normal" font="default" size="100%">Srivani Telapolu</style></author><author><style face="normal" font="default" size="100%">Chamundeeswari Duraipandian</style></author><author><style face="normal" font="default" size="100%">Thyagarajan Sadras Panchatcharam</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hydroalcoholic and Alkaloidal Extracts of Murraya koenigii(L.) Spreng Augments Glucose Uptake Potential against Insulin Resistance Condition in L6 Myotubes and Inhibits Adipogenesis in 3T3L1 Adipocytes</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">complications</style></keyword><keyword><style  face="normal" font="default" size="100%">Diabetes</style></keyword><keyword><style  face="normal" font="default" size="100%">glucose uptake</style></keyword><keyword><style  face="normal" font="default" size="100%">L6 myotubes</style></keyword><keyword><style  face="normal" font="default" size="100%">Mahanine</style></keyword><keyword><style  face="normal" font="default" size="100%">α - amylase</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2018</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June 2018</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/642</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">10</style></volume><pages><style face="normal" font="default" size="100%">633-639</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; &lt;em&gt;Murraya koenigii&lt;/em&gt;, commonly known as &amp;ldquo;curry leaves&amp;rdquo; is native to India. The highly valued part of the plant is the leaves which possess various biological activities. &lt;strong&gt;Objective:&lt;/strong&gt; The present study aimed to investigate the antidiabetic effect of &lt;em&gt;Murraya koenigii&lt;/em&gt; (MK) leaf extracts, of two different solvent ratios. &lt;strong&gt;Materials and methods:&lt;/strong&gt; 70% hydroalcoholic and alkaloidal extracts of MK leaves were prepared by cold maceration method. Preliminary phytochemical analysis was carried out for both the extracts. &lt;em&gt;In vitro&lt;/em&gt; anti diabetic activity was screened by inhibitory action on &amp;alpha; &amp;ndash; amylase, &amp;alpha; &amp;ndash; glucosidase enzymes. Further, the 70% hydroalcoholic and alkaloidal extracts were assessed for glucose uptake potential, anti - adipogenic property, as well as inhibitory activity on diabetes associated complications. HPTLC quantification of major phytoconstituent was carried out. &lt;strong&gt;Results:&lt;/strong&gt; The study showed presence of various phytoconstituents such as, polyphenols, alkaloids, tannins, reducing sugars etc. The 70% hydroalcoholic and alkaloidal extracts of MK leaves exhibited &amp;gt;90% inhibition against carbohydrate metabolising enzymes compared to aqueous and absolute alcohol extracts. Both the extracts showed enhanced glucose uptake in L6 myotubes attenuating the effect of Palmitate induced insulin resistance. Significant inhibition on adipogenesis was exerted by both 70% hydroalcoholic and alkaloidal extracts of MK leaves. Besides, marked inhibition of advanced glycation end products was exhibited by the extracts. HPTLC quantification analysis of the aforementioned extracts showed the presence of major phytoconstituent, Mahanine, in it. &lt;strong&gt;Conclusion:&lt;/strong&gt; The results of the present study showed that MK possesses significant antidiabetic property and also exhibited considerable effect in preventing diabetes associated complications. The potent antidiabetic activity of MK could be attributed to the presence of Mahanine, the major active constituent, which is a carbazole alkaloid.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">633</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Parameswari Royapuram Parthasarathy&lt;sup&gt;1&lt;/sup&gt;, Janani Murthy&lt;sup&gt;1&lt;/sup&gt;, Dinesh Murugan Girija&lt;sup&gt;1&lt;/sup&gt;, Srivani Telapolu&lt;sub&gt;1&lt;/sub&gt;, Chamundeeswari Duraipandian&lt;sup&gt;2&lt;/sup&gt;, Thyagarajan Sadras Panchatcharam&lt;sup&gt;3&lt;/sup&gt;* &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;SRMC Centre for Indian Systems of Medicine, Quality assurance and Standardization, Central Research Facility, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy, Faculty of Pharmacy, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Central Research Facility, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Thriveni Vasanthkumar</style></author><author><style face="normal" font="default" size="100%">Manjunatha Hanumanthappa</style></author><author><style face="normal" font="default" size="100%">Prabhakar BT</style></author><author><style face="normal" font="default" size="100%">Santhosh Kondajji Hanumanthappa</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective Effect of Curcumin and Capsaicin against Lipopolysaccharide Induced Liver Damage in Mice</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">ALP.</style></keyword><keyword><style  face="normal" font="default" size="100%">Capsaicin</style></keyword><keyword><style  face="normal" font="default" size="100%">Curcumin</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatoprotective activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipopolysaccharide</style></keyword><keyword><style  face="normal" font="default" size="100%">SGOT</style></keyword><keyword><style  face="normal" font="default" size="100%">SGPT</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/201</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">947-951</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The present study was undertaken to evaluate the possible ameliorative role of curcumin, capsaicin and their combination against lipopolysaccharide (LPS) induced hepatic toxicity in mice. &lt;strong&gt;Methods:&lt;/strong&gt; Animals were distributed into five experimental groups: Normal control, vehicle control, curcumin, capsaicin and combined curcumin and capsaicin treatment groups respectively, for 7 days prior to LPS induced liver toxicity (3 mg/kg b.w. in saline). Hepatoprotective effect of individual and combined spice principles were evidenced by the measurement of serum marker enzyme activities such as, SGPT, ALP and TB and it was further confirmed by histopathological observation of liver tissue section. &lt;strong&gt;Results:&lt;/strong&gt; The administration of LPS increased serum nonspecific enzymes (SGOT; 174.2&amp;plusmn;3.79 IU/L, SGPT; 124.0&amp;plusmn;3.14 IU/L, ALP; 320.15&amp;plusmn;3.88 IU/L and total bilirubin level; 2.32&amp;plusmn;1.23 mg/dL), however dietary curcumin and capsaicin decreased the activities of these non&amp;ndash;specific serum enzymes including total bilirubin indicating amelioration of the severe LPS induced hepatotoxicity, while the combined spice principles were more significant as shown by the levels of enzymes activities SGOT; 89.9&amp;plusmn;1.39 IU/L, SGPT; 85.9&amp;plusmn;1.83 IU/L, ALP; 138.4&amp;plusmn;2.05 IU/L including total bilirubin level; 0.86&amp;plusmn;0.03 mg/dL. &lt;strong&gt;Conclusion:&lt;/strong&gt; Dietary curcumin and capsaicin individually are protective to LPS induced hepatotoxicity, the beneficial effect was found to be more when the two compounds were fed in combination.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">947</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Thriveni Vasanthkumar&lt;sup&gt;1&lt;/sup&gt;, Manjunatha Hanumanthappa&lt;sup&gt;1&lt;/sup&gt;, Prabhakar BT&lt;sup&gt;2&lt;/sup&gt;, Santhosh Kondajji Hanumanthappa&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biotechnology, Kuvempu University, Shankaraghatta - 577 451 Shimoga, Karnataka (St), INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Molecular biomedicine laboratory, Postgraduate department of studies and research in biotechnology, Sahyadri science college, Kuvempu University, Shimoga-577203, Karnataka (St), INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Gayathri Megashyam Rao</style></author><author><style face="normal" font="default" size="100%">Sudhanshu Sekhar Sahu</style></author><author><style face="normal" font="default" size="100%">Beena Vichithra Shetty</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hindering Effect of Resveratrol on Oxidative Changes and Na&lt;sup&gt;+&lt;/sup&gt;K&lt;sup&gt;+&lt;/sup&gt;-ATPase activity in Rat Hepatocytes Exposed to Prenatal stress</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Cortisol</style></keyword><keyword><style  face="normal" font="default" size="100%">Na+K+-ATPa</style></keyword><keyword><style  face="normal" font="default" size="100%">Oxidative Changes</style></keyword><keyword><style  face="normal" font="default" size="100%">Prenatal Stress</style></keyword><keyword><style  face="normal" font="default" size="100%">Resveratrol</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">/files/pj-9-5/10.5530pj.2017.5.98/index.html</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">615-620</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; The fetal programming hypothesis states that conditions during pregnancy, including stress, will have long-term effects on adult health, probably via epigenetic mechanisms. &lt;strong&gt;Methodology:&lt;/strong&gt; Pregnant rats were subjected to restrain stress either during early or late pregnancy with and without resveratrol. Blood and liver tissues were collected from 40 days old offsprings of the above rats to study the prenatal effect on corticosterone, and stress development. &lt;strong&gt;Results:&lt;/strong&gt; It was found that levels of corticosterone advanced protein and lipid oxidation products, GSHRx, increase significantly in offsprings of stressed rats and decreased on intervention with resveratrol, whereas total antioxidants, vitamin C, GSH, SOD and Na+K+- ATPase decreased with stress and increase on resveratrol intervention as compared to controls. &lt;strong&gt;Conclusion:&lt;/strong&gt; The alterations may be due to the effect of stress on HPA axis. Results also support the prevention/protective effect of resveratrol on oxidative stress and may be used as a measure to prevent the metabolic changes in adult life due to prenatal stress.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">615</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Gayathri Megashyam Rao, Sudhanshu Sekhar Sahu, Beena Vichithra Shetty&lt;sup&gt;* &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Biochemistry, Kasturba Medical College, Mangaluru, Manipal University, Karnataka, INDIA.&amp;nbsp;&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Madathilparambil Vasu Sudhakaran</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Histo-Chromatographic Finger Printing Profiles of the Root of Plumbago zeylanica Linn and Quantification of Marker Compound, Plumbagin</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Axial Parenchyma</style></keyword><keyword><style  face="normal" font="default" size="100%">Calibration Curve</style></keyword><keyword><style  face="normal" font="default" size="100%">Mesomorphy Ratio</style></keyword><keyword><style  face="normal" font="default" size="100%">Plumbagin</style></keyword><keyword><style  face="normal" font="default" size="100%">Tylosis</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/386</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">s77-s86</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Plumbagin, a plant-derived naphthoquinone is known to be biosynthesized by polyacetate-malonate pathway. The ayurvedic drug Chitraka is obtained from the medicinal plant &lt;em&gt;Plumbago zeylanica&lt;/em&gt; Linn, which belongs to the family Plumbaginaceae. The Chitraka is found used in the traditional forms of medicine for the treatment of various illnesses, since ancient times. &lt;strong&gt;Aim:&lt;/strong&gt; The present study concerns the microscopic, powder and quantitative microscopic characteristics of the root of &lt;em&gt;Plumbago zeylanica&lt;/em&gt; Linn. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; Delimiting the morpho-histological profile of the root using digital, stereo and polarized microscopic techniques and to develop the chromatogram of the extract of the root of &lt;em&gt;Plumbago zeylanica&lt;/em&gt; Linn using High performance thin-layer chromatographic (HPTLC) method. &lt;strong&gt;Results:&lt;/strong&gt; The presence of cortical deposition of plumbagin pigment as yellowish tints in the surface view of the sections of root, arrangement of starch grains as bunches of grapes in cortical tissues and ray parenchyma, crystal idioblasts containing calcium oxalate embedded in the intervening walls of the cortical cells, distinct band or patch of sclreids at the pericyclic region of the phloem, wood with non-storied cambium, distinct growth ring boundaries, paratracheal axial parenchyma, chains of vessels in radial multiplies of three to four, uniseriate to biseriate medullary rays with homogeneous cells, crowding of vessels at the central portion of secondary xylem, wood plugged with tylosis and low mesomorphy ratio for wood were the anatomical features characteristics of the taxon. The HPTLC profile of the methanol extract of root developed using the mobile phase, n-hexane:ethyl acetate (8:2 v/v) had revealed four phytoconstituents. The R&lt;sub&gt;f&lt;/sub&gt; value for plumbagin (C&lt;sub&gt;11&lt;/sub&gt;H&lt;sub&gt;8&lt;/sub&gt;O&lt;sub&gt;3&lt;/sub&gt;) was found to be 0.86. Densitometric scanning had shown &amp;lambda;&lt;sub&gt;max&lt;/sub&gt; of plumbagin at 270 nm. Spectral matching by overlaying the spectra of both standards and extract of root sample were confirmed the specificity of &amp;lambda;&lt;sub&gt;max&lt;/sub&gt; at 270 nm for the marker compound. The calibration curve was found to be linear in the concentration range of 2.00 to 10.00 &amp;mu;g/ band with the polynomial calibration equation Y=178.8+91.61*X+-4.825*X&lt;sup&gt;2&lt;/sup&gt; and estimated that 5 &amp;mu;L of methanol extract of roots contained 1.326 &amp;mu;g of plumbagin. Thus the content of marker constituent (plumbagin) present in shade-dried roots of &lt;em&gt;Plumbago zeylanica&lt;/em&gt; Linn (a Kerala habitant) was estimated as 0.179%. &lt;strong&gt;Conclusion:&lt;/strong&gt; The present study suggests that the delineated characteristics of the roots of &lt;em&gt;Plumbago zeylanica&lt;/em&gt; Linn could tag as the identifying parameters to substantiate and authenticate the raw drugs from the spurious/adulterants materials and developed HPTLC method could be effectively used for the regulatory perspectives and quality assessment of plumbagin in the polyherbal formulation/finished products of traditional medicine.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s77</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Madathilparambil Vasu Sudhakaran &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;UGC Academic Staff College, University of Calicut, Calicut University PO, Malappuram -673635, Kerala, INDIA&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Ma Yue-ling</style></author><author><style face="normal" font="default" size="100%">Chen Yu-jie</style></author><author><style face="normal" font="default" size="100%">Wan Ding-rong</style></author><author><style face="normal" font="default" size="100%">Chen ping</style></author><author><style face="normal" font="default" size="100%">Xu Ran</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">HPLC Determination of Quercetin in Three Plant Drugs from Genus Sedum and Conjecture of the Best Harvest Time</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">best harvest time.</style></keyword><keyword><style  face="normal" font="default" size="100%">Genus Sedum</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC determination</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant medicines</style></keyword><keyword><style  face="normal" font="default" size="100%">Quercetin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/167</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">725-728</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;To establish a method for quercetin content determination of the three plant drugs from genus Sedum and to decide their best harvesting time. Dried herbs of Sedum sarmentosum Bunge., &lt;em&gt;S. lineare&lt;/em&gt; Thunb. and &lt;em&gt;S. erythrostictum&lt;/em&gt; Migo. are all traditional medicines from Genus Sedum. They all have long been used to cure hepatitis, dysentery, swelling poison and so on. It has been reported that flavonoids contained in &lt;em&gt;S. sarmentosum&lt;/em&gt; Bunge. were one type of the active components to protect liver and reduce serum alanine aminotransferase level. Through the qualitative analysis and TLC assay, we have verified that both &lt;em&gt;S. lineare&lt;/em&gt; Thunb. and &lt;em&gt;S. sarmentosum&lt;/em&gt; Bunge. contain flavonoid glycosides whose aglycones include quercetin. In this study, a HPLC methodology was established to determine quercetin which was a common hydrolyzate of the flalvonoid glycosides in the three plant medicines. The determination method developed showed good linearity in the range of 41.2-412.0 &amp;mu;g/mL, and had a nice accuracy and repeatability. It indicated that the content of quercetine in Sedum sarmentosum, Sedum lineare and Sedum emarginatum can achieve the quality standard required by Chinese Pharmacopoeia.( No less than 0.01%), The results also revealed preliminarily a relation between collected season and medicine quality. Thus it could be used to control some flavonoids content in the three plant drugs indirectly. By determining the samples of the 3 drugs collected in different seasons, the optimal harvest periods could be preliminarily ascertained.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">725</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Ma Yue-ling&lt;sup&gt;1&lt;/sup&gt;, Chen Yu-jie&lt;sup&gt;2&lt;/sup&gt;, Wan Ding-rong&lt;sup&gt;3&lt;/sup&gt;, Chen Ping&lt;sup&gt;1&lt;/sup&gt;, and Xu Ran&lt;sup&gt;1*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;School of biological and pharmaceutical engineering, Wuhan Polytechnic University, Wuhan, 430023, CHINA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Shandong Center for Drug Evaluation &amp;amp; Certification, Jinan, CHINA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;College of Pharmacy, South-Central University for Nationalities, Wuhan, 430074, CHINA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Diangang Liu</style></author><author><style face="normal" font="default" size="100%">Qing Mei</style></author><author><style face="normal" font="default" size="100%">Weifang Long</style></author><author><style face="normal" font="default" size="100%">Xiangluan Wan</style></author><author><style face="normal" font="default" size="100%">Dingrong Wan</style></author><author><style face="normal" font="default" size="100%">Luyao Wang</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">HPLC Fingerprint Analysis and Content Determination of Extract with Anticancer Activities of Sedi Linearis Herba</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anticancer Activity Ingredients</style></keyword><keyword><style  face="normal" font="default" size="100%">Content Determination</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC Fingerprint</style></keyword><keyword><style  face="normal" font="default" size="100%">Sedum lineare Thunb.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">February 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://phcogj.com/fulltext/289</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">128-134</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Aims:&lt;/strong&gt; The purpose of this paper was to develop a HPLC fingerprint analysis method, compare the chromatographic fingerprints characteristics of the ethyl acetate extract with anticancer activity from Sedi Linearis Herba (&lt;em&gt;Sedum lineare&lt;/em&gt; Thumb.) collected in different seasons and environments, determine the contents of active ingredients hyperoside, isoquercetin and astragalin of each sample by HPLC, provide believable scientific foundations for quality control and evaluation of Sedi Linearis Herba. &lt;strong&gt;Methods:&lt;/strong&gt; The analyte was analyzed using BDS Hypersil C&lt;sub&gt;18&lt;/sub&gt; as chromatographic column, acetonitrile -0.1% acetic acid solution as the mobile phase (gradient elution). &lt;strong&gt;Results:&lt;/strong&gt; The results showed that the major active ingredient contents of the samples collected in different seasons but at the same environment all had obvious differences. These ingredient contents of the samples collected in the end of April were much more than those in mid-August in general. Moreover, the major active ingredient contents of the samples picked in the same season but different environments were different too. For instance, the major ingredient contents of the sample in damp environment in August were more than those in sunny environment. &lt;strong&gt;Conclusion:&lt;/strong&gt; All of these indicated that the HPLC fingerprint analysis and contents determination method established were very useful for quality analysis and control of Sedi Linearis Herba.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">128</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Diangang Liu&lt;sup&gt;1&lt;/sup&gt;, Qing Mei&lt;sup&gt;2&lt;/sup&gt;, Weifang Long&lt;sup&gt;2&lt;/sup&gt;, Xiangluan Wan&lt;sup&gt;1&lt;/sup&gt;, Dingrong Wan&lt;sup&gt;2&lt;/sup&gt;, Luyao Wang* &lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacy, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, CHINA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacy, College of Pharmacy, South-Central University for Nationalities, Wuhan, CHINA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;School of Chinese Medicine,Hong Kong Baptist University,Hong Kong,CHINA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Sakshi Bajaj</style></author><author><style face="normal" font="default" size="100%">Sharad Wakode</style></author><author><style face="normal" font="default" size="100%">Washim Khan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">HPTLC Analysis and Antiproliferative Effect of Various Extracts of Swertia alata on Growth of Leishmania donovani Promastigotes in vitro</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Antiproliferative</style></keyword><keyword><style  face="normal" font="default" size="100%">HPTLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Oleanolic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Quality control</style></keyword><keyword><style  face="normal" font="default" size="100%">Swertiamarin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">November 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/391</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">s107-s116</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;The present study was carried out to evaluate the quality control analysis and antiproliferative effects of petroleum ether, chloroform, ethanol and aqueous extracts of Swertia alata (family Gentianaceae) on Leishmania donovani. A basic, exact, quick and reproducible high performance thin layer chromatography (HPTLC) has been created for synchronous analysis of Oleanolic acid and Swertiamarin from S. alata. &lt;/p&gt;

Read more...</style></abstract><issue><style face="normal" font="default" size="100%">6s</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">s107</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Sakshi Bajaj&lt;sup&gt;1&lt;/sup&gt;*, Sharad Wakode&lt;sup&gt;2&lt;/sup&gt;, Washim Khan&lt;sup&gt;3 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacognosy and Phytochemistry, University of Delhi, DIPSAR, Sec-III, Pushp Vihar, M.B Road, Delhi-110017, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Professor, Department of Pharmaceutical Chemistry, University of Delhi, DIPSAR, Sec-III, Pushp Vihar, M.B Road, Delhi-110017, INDIA.&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Ph.D Scholar, Faculty of Pharmacy, Department of Pharmacognosy and Phytochemistry, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi - 110062, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Teeraporn Katisart</style></author><author><style face="normal" font="default" size="100%">Surapong Rattana</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hypoglycemic Activity of Leaf Extracts from Tiliacora triandra in Normal and Streptozotocin-Induced Diabetic Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Hypoglycemic Effect</style></keyword><keyword><style  face="normal" font="default" size="100%">Streptozotocin-Induced Diabetic Rats.</style></keyword><keyword><style  face="normal" font="default" size="100%">Tiliacora triandra</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">July 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">/files/pj-9-5/10.5530pj.2017.5.99/index.html</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">621-625</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; &lt;em&gt;Tiliacora triandra&lt;/em&gt; is a common plant found in southeast Asian countries. It is traditionally used as anti-pyrogenic agent. &lt;strong&gt;Objective:&lt;/strong&gt; The present study was aimed to investigate the hypoglycemic activities leaf extracts from &lt;em&gt;Tiliacora triandra&lt;/em&gt; (TTE) in normal and streptozotocin- induced diabetic rats. &lt;strong&gt;Methods:&lt;/strong&gt; TTE was prepared and daily and orally administered at dose of 300 mg/kg b.w. to the rats for 8 weeks. The body weight and blood glucose level were measured weekly. At the end of the experiments, blood samples were collected from cardiac puncture and analyzed for serum insulin levels. The pancreatic tissues were stained by hematoxylin-eosin for histo-pathological investigations. &lt;strong&gt;Results:&lt;/strong&gt; Normal and diabetic rats treated with TTE and glibenclamide tended to have an increased body weight. TTE significantly decreased the blood glucose level by 25.01 &amp;plusmn; 19.77% in week 3 in diabetic rats and similar to that of glibenclamide group (27.01 &amp;plusmn; 11.89%). However, the extracts slightly decreased the blood glucose level in normal rats by 9.48 &amp;plusmn; 2.14% in week 2. TTE significantly increased serum insulin level by 21.63 &amp;plusmn; 1.39 IU/mL in diabetic rats compared to the controls (10.63 &amp;plusmn; 0.37 IU/mL) but not in normal rats. In additions, TTE activated the regeneration of pancreatic Islets of Langerhans in diabetic rats which in turn stimulated insulin secretion. &lt;strong&gt;Conclusion:&lt;/strong&gt; TTE exhibits the hypoglycemic potential by stimulating insulin secretion from the pancreas.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">621</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Teeraporn Katisart&lt;sup&gt;1*&lt;/sup&gt;, Surapong Rattana&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biology, Faculty of Science, Mahasarakham University, THAILAND&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Pharmaceutical chemistry and Natural Products Research Unit, Faculty of Pharmacy, Mahasarakham University, THAILAND&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Piyapong Yupparach</style></author><author><style face="normal" font="default" size="100%">Ampa Konsue</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hypoglycemic and Hypolipidemic Activities of Ethanolic Extract from Mimosa pudica L. in Normal and Streptozotocin-Induced Diabetic Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Hypoglycemic</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypolipidemic</style></keyword><keyword><style  face="normal" font="default" size="100%">Mimosa pudica</style></keyword><keyword><style  face="normal" font="default" size="100%">Oral glucose tolerance test.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2017</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://fulltxt.org/article/183</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">9</style></volume><pages><style face="normal" font="default" size="100%">834-837</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Context:&lt;/strong&gt; &lt;em&gt;Mimosa pudica&lt;/em&gt; L. its unique property to collapse when touched and opens up. &lt;strong&gt;Aims:&lt;/strong&gt; To evaluate hypoglycemic and hypolipidemic activities of 80% ethanolic extract from whole plant of &lt;em&gt;Mimosa pudica&lt;/em&gt; L. (MPE) by measuring fasting blood glucose in normal and streptozotocin (STZ)-induced diabetic rats treated with MPE. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; An eight-week study using MPE was performed in normal and streptozotocin (STZ)-induced diabetic rats. Hypoglycemic activities in normal and STZ-induced diabetic rats and oral glucose tolerance test (OGTT) and biochemical data include total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL) and low-density lipoprotein (LDL) of MPE were compared with glibenclamide, a standard anti-diabetic drug. &lt;strong&gt;Results:&lt;/strong&gt; OGTT showed that MPE did not decrease blood glucose both in normal and STZ-induced diabetic rats comparable to controls and glibenclamide treated rats. Moreover, MPE did not affect FBG in the normal rats. However, it significantly (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.05) decreased FBG in the diabetic rats while MPE increased HDL and decreased TC, TG and LDL in the diabetic rats. &lt;strong&gt;Conclusions:&lt;/strong&gt; The results from this study confirmed the traditional use of &lt;em&gt;Mimosa pudica&lt;/em&gt; L. for the treatment of diabetes mellitus.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">834</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Piyapong Yupparach, Ampa Konsue&lt;sup&gt;*&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;
&lt;p style=&quot;text-align: justify;&quot;&gt;Faculty of Medicine, Mahasarakham University, Maha Sarakham, 44000, THAILAND.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Mohammad Ali</style></author><author><style face="normal" font="default" size="100%">Mruthunjaya Kenganora</style></author><author><style face="normal" font="default" size="100%">Santhepete Nanjundaiah Manjula</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Health Benefits of Morinda citrifolia (Noni): A Review</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anticancer.</style></keyword><keyword><style  face="normal" font="default" size="100%">Antioxidant</style></keyword><keyword><style  face="normal" font="default" size="100%">Morinda citrifolia</style></keyword><keyword><style  face="normal" font="default" size="100%">Neutraceutical</style></keyword><keyword><style  face="normal" font="default" size="100%">Phyto-constituents</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">June/2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">321-334</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Morinda citrifolia &lt;/em&gt;(Noni) has been used widely as a complementary and alternative therapy in many countries owing to its potent antioxidant activity and proven health benefits. Traditionally, it finds used as a therapeutic remedy to various diseases as an antibacterial, antitumor, anthelminthic, analgesic, anti-inflammatory, immunostimulant. Also it has proved beneficial in conditions like gastritis, skin diseases, respiratory infections, menstrual and urinary tract disorders, fever, diabetes and venereal diseases. &lt;strong&gt;Objective:&lt;/strong&gt; This review emphasizes on the phytochemical and mineral profile of the different parts of Noni plant. In addition, this review corroborates the pharmacological basis for the various health benefits, traditional and medicinal applications of Noni. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; All the available information of Noni were collected from electronic databases such as Academic Journals, Ethnobotany, Ethnopharmacology, Springer, PubMed, Google Scholar, Science Direct and other primary and secondary sources.&lt;strong&gt; Results:&lt;/strong&gt; According to our search results pertaining to scientific literature, &lt;em&gt;Morinda citrifolia&lt;/em&gt; is used for more than 40 types of ailments worldwide. Crude extract of various parts of plant and fruit juice are reported to contain amino acids, anthraquinones, fatty acids, flavonoids, iridoids, lignans, polysaccharides, sterols, sugars, terpenoids etc. which are therapeutically useful for a broad range of pathological conditions. Fourteen human clinical trials have validated the remarkable health benefits of Noni. &lt;strong&gt;Conclusion:&lt;/strong&gt; Literatures prove that Noni is pharmacologically active and is used in different forms of cancer, viz. colon, esophageal, breast, colorectal cancers; cardiovascular diseases, diabetes, arthritis, hypertension. These properties are substantiated by the preclinical or/and clinical investigations.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Review Article</style></work-type><section><style face="normal" font="default" size="100%">321</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Mohammad Ali, Mruthunjaya Kenganora, Santhepete Nanjundaiah Manjula* &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacology, JSS College of Pharmacy, JSS University, Sri Shivarathreeshwara Nagar- 570015, Dist-Mysore, State- Karnataka, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Varsha Raj</style></author><author><style face="normal" font="default" size="100%">Arun Kumar Mishra</style></author><author><style face="normal" font="default" size="100%">Amrita Mishra</style></author><author><style face="normal" font="default" size="100%">Najam Ali Khan</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective effect of Prunus armeniaca L. (Apricot) leaf extracts on Paracetamol induced liver damage in Wistar rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Apricot</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Liver toxicity.</style></keyword><keyword><style  face="normal" font="default" size="100%">Paracetamol</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">December 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">154-158</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align:justify&quot;&gt;&lt;strong&gt;Objective&lt;/strong&gt;: To evaluate the hepatoprotective effect of &lt;em&gt;Prunus armeniaca&lt;/em&gt; L. (Apricot) leaf on paracetamol induced liver toxicity in rats. &lt;strong&gt;Method: &lt;/strong&gt;Phytochemical investigation was performed to find active constituents of the plant extracts by the different phytochemical tests. After induction of liver toxicity, the biochemical parameters such as serum glutamic pyruvic transaminase (sGPT), serum glutamic oxaloacetic transaminase (sGOT), serum alkaline phosphatase (sALP), serum bilirubin (SB), thiobarbituric acid reactive substances (TBARS), &amp;gamma;-glutamyl transferase (GGT), lactate dehydrogenase (LDH), total protein (TP), albumin. The physical parameters including liver weight, body weight and histopathological changes in the liver were studied with Ursodeoxycholic acid as standard hepatoprotective agents.&lt;strong&gt; Results: &lt;/strong&gt;The phytochemical investigation of the extracts showed the presence of Alkaloids, volatile oil, saponin glycosides, condensed tanins, terpenoids, steroids and flavonoids. Methanol and aqueous extract before the paracetamol administration caused a significant reduction in the values of sGOT, sGPT, sALP, TBARS, GGT, LDH TP, Albumin and sB (P&amp;lt;0.01) almost comparable to the Ursodeoxycholic acid. The hepatoprotective activity was confirmed by histopathological examination of the liver tissue of control and treated animals. &lt;strong&gt;Conclusions:&lt;/strong&gt; The result concludes that &lt;em&gt;Prunus armeniaca&lt;/em&gt; L. possesses the hepatoprotective effect against paracetamol induced liver toxicity in rats.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">154</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align:justify&quot;&gt;&lt;strong&gt;Varsha Raj*, Arun Kumar Mishra, Amrita Mishra, Najam Ali Khan&lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align:justify&quot;&gt;Department of Pharmacy, Pharmacology Research Lab, IFTM University, Moradabad, 244102, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Shaik Aminabee</style></author><author><style face="normal" font="default" size="100%">Atmakuri Lakshmana Rao</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">Maram Chinna Eswaraiah</style></author></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective Activity of Michelia nilagirica against Paracetamol Induced Hepatic Injury in Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Albino rats</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatoprotective</style></keyword><keyword><style  face="normal" font="default" size="100%">Michelia nilagirica</style></keyword><keyword><style  face="normal" font="default" size="100%">Paracetamol</style></keyword><keyword><style  face="normal" font="default" size="100%">Screening</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Jul-Aug 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">228-235</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Background:&lt;/strong&gt; Michelia nilagirica belonging to the family Mangoliaceae is commonly used by many traditional healers in most of the herbal preparations for diabetes and kidney diseases. &lt;strong&gt;Objective: &lt;/strong&gt;Different fractions isolated from ethanolic extract of whole plant of Michelia nilagirica is investigated for hepatoprotective activity in wistar albino rats against paracetamol induced hepatic injury. &lt;strong&gt;Materials &amp;amp; Methods:&lt;/strong&gt; Rats were divided into eight groups. Each group contains six animals. Hepatic injury was achieved by injecting paracetamol at a dose of 2 mg/kg p.o. &lt;strong&gt;Results:&lt;/strong&gt; The hepatoprotective action is seen with fraction A by reduction in serum marker enzymes like Aspartate transaminase (AST), Alanine transaminase (ALT). It also reduced the elevated levels of Alkaline phosphotase (ALP) &amp;amp; Serum bilirubin. &lt;strong&gt;Conclusion:&lt;/strong&gt; Histopathological studies further confined the hepatoprotective activity of fraction A against paracetamol treated group. The results obtained were compared with silymarin (100 mg/kg, orally), a standard drug.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">228</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Shaik Aminabee&lt;sup&gt;1&lt;/sup&gt;, Atmakuri Lakshmana Rao&lt;sup&gt;*1&lt;/sup&gt; and Maram Chinna Eswaraiah&lt;sup&gt;2 1&lt;/sup&gt;&lt;/strong&gt;Department of Pharmacology, V. V. Institute of Pharmaceutical Sciences, Gudlavalleru, Andhra Pradesh, INDIA 2Department of Pharmacognosy, Anurag College of Pharmacy, Kodad, Telangana, INDIA.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Shaik Aminabee</style></author><author><style face="normal" font="default" size="100%">Atmakuri Lakshmana Rao</style></author><author><style face="normal" font="default" size="100%">Maram Chinna Eswaraiah</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective Activity of Michelia nilagirica against Paracetamol Induced Hepatic Injury in Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Albino rats</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatoprotective</style></keyword><keyword><style  face="normal" font="default" size="100%">Michelia nilagirica</style></keyword><keyword><style  face="normal" font="default" size="100%">Paracetamol</style></keyword><keyword><style  face="normal" font="default" size="100%">Screening.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">29th Apr, 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">228-235</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt;&lt;em&gt;Michelia nilagirica&lt;/em&gt; belonging to the family &lt;em&gt;Mangoliaceae&lt;/em&gt; is commonly used by many traditional healers in most of the herbal preparations for diabetes and kidney diseases. &lt;strong&gt;Objective:&lt;/strong&gt; Different fractions isolated from ethanolic extract of whole plant of Michelia nilagirica is investigated for hepatoprotective activity in wistar albino rats against paracetamol induced hepatic injury. &lt;strong&gt;Materials &amp;amp; Methods: &lt;/strong&gt;Rats were divided into eight groups. Each group contains six animals. Hepatic injury was achieved by injecting paracetamol at a dose of 2 mg/kg p.o. &lt;strong&gt;Results: &lt;/strong&gt;The hepatoprotective action is seen with fraction A by reduction in serum marker enzymes like Aspartate transaminase (AST), Alanine transaminase (ALT). It also reduced the elevated levels of Alkaline phosphotase (ALP) &amp;amp; Serum bilirubin. &lt;strong&gt;Conclusion:&lt;/strong&gt; Histopathological studies further confined the hepatoprotective activity of fraction A against paracetamol treated group. The results obtained were compared with silymarin (100 mg/kg, orally), a standard drug.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words: &lt;/strong&gt;Albino rats, Hepatoprotective, &lt;em&gt;Michelia nilagirica&lt;/em&gt;, Paracetamol, Screening.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">4</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">228</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Shaik Aminabee&lt;sup&gt;1&lt;/sup&gt;, Atmakuri Lakshmana Rao&lt;sup&gt;*1&lt;/sup&gt; and Maram Chinna Eswaraiah&lt;sup&gt;2 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, V. V. Institute of Pharmaceutical Sciences, Gudlavalleru, Andhra Pradesh, INDIA&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy, Anurag College of Pharmacy, Kodad, Telangana, INDIA.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rajesh A Maheshwari,</style></author><author><style face="normal" font="default" size="100%">Bhagyashree Pandya</style></author><author><style face="normal" font="default" size="100%">R. Balaraman, Avinash K Seth</style></author><author><style face="normal" font="default" size="100%">Yogesh Chand</style></author><author><style face="normal" font="default" size="100%">Yadav</style></author><author><style face="normal" font="default" size="100%">Vasa Siva Sankar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective effect of Livplus- A polyherbal formulation</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acetylcholine</style></keyword><keyword><style  face="normal" font="default" size="100%">Antitussive</style></keyword><keyword><style  face="normal" font="default" size="100%">Bronchoprotection</style></keyword><keyword><style  face="normal" font="default" size="100%">Citric acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Cough</style></keyword><keyword><style  face="normal" font="default" size="100%">Cough variant asthma (CVA)</style></keyword><keyword><style  face="normal" font="default" size="100%">Ethanolic extract of Woodfordia fruticosa (L.) Kurz (EEWF)</style></keyword><keyword><style  face="normal" font="default" size="100%">Histamine.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">9th June 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">4-4</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;Nill&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">4</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Rajesh A Maheshwari&lt;sup&gt;*&lt;/sup&gt;, Bhagyashree Pandya, R. Balaraman, Avinash K Seth, Yogesh Chand Yadav, Vasa Siva Sankar &lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacy, Sumandeep Vidyapeeth, Piparia, Vadodara-391760, Gujarat, India&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rajesh Maheshwari</style></author><author><style face="normal" font="default" size="100%">Bhagyashree Pandya</style></author><author><style face="normal" font="default" size="100%">Ramachandran Balaraman</style></author><author><style face="normal" font="default" size="100%">Avinash Kumar Seth</style></author><author><style face="normal" font="default" size="100%">Yogesh Chand Yadav</style></author><author><style face="normal" font="default" size="100%">Vasa Siva Sankar</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective effect of Livplus-A polyherbal formulation</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">CCl4</style></keyword><keyword><style  face="normal" font="default" size="100%">GGT</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatic enzymes.</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Livplus</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">01/2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">311-316</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; The aim of the present study was to investigate the hepatoprotective effect of Livplus (a polyherbal formulation) against CCl&lt;sub&gt;4&lt;/sub&gt;-induced hepatotoxicity in rats. &lt;strong&gt;Methods:&lt;/strong&gt; Hepatotoxicity was induced in rats by i.p. injection of CCl&lt;sub&gt;4&lt;/sub&gt; once three days for 14 days. Livplus or Silymarin was administered along with CCl&lt;sub&gt;4&lt;/sub&gt; and the biochemical parameters like aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkalinephosphatase (ALP), total bilirubin (TB), direct bilirubin, total protein (TP), gamma-glutamyl transferase (GGT), total cholesterol (TC) and triglycerides (TG) were estimated. Furthermore, biomarkers of oxidative stress such as MDA levels, Glutathione contents, SOD and catalase activity in liver tissue were estimated. &lt;strong&gt;Results:&lt;/strong&gt; Treatment with Livplus significantly reduced the elevated levels of ALT, AST, ALP, bilirubin (direct and total), GGT, TC, TG and increased levels of TP compared to CCl&lt;sub&gt;4&lt;/sub&gt; control rats. The treatment with Livplus also showed a significant increase in glutathione contents, SOD and catalase activity and a decrease in MDA levels compared to CCl&lt;sub&gt;4&lt;/sub&gt; control rats. &lt;strong&gt;Conclusion:&lt;/strong&gt; The finding of present study indicates that Livplus showed a potential hepatoprotective activity. These results support the traditional use of Livplus in the treatment of liver disorders.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">311</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Rajesh Maheshwari&lt;sup&gt;*&lt;/sup&gt;, Bhagyashree Pandya, Ramachandran Balaraman, Avinash Kumar Seth, Yogesh Chand Yadav and Vasa Siva Sankar&lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;Department of Pharmacy, Sumandeep Vidyapeeth, Piparia, Vadodara, Gujarat, India.&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dandare Shamsudeen Umar</style></author><author><style face="normal" font="default" size="100%">Bawa Muhammad</style></author><author><style face="normal" font="default" size="100%">Wasagu Ibrahim Zubairu</style></author><author><style face="normal" font="default" size="100%">Magaji Umar Faruk</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective effect of Quail egg against carbon tetra chloride (CCl4) induced hepatic damage in albino rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Mar-Apr 2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">102-106</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Quail egg has been used traditionally in the treatment of many ailments. Despite the wide speculations of its involvement in the treatment of liver diseases, very little scientific evidence exist to support this claim. This work investigated the hepatoprotective effect of quail egg against carbon tetrachloride (CCl4) induced liver damage in albino rats. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; The rats were divided into five groups of five rats per group. Animals of group A (positive control) were fed with vehicle (distilled water) on the first four days and with vehicle and CCl4 on the fifth, sixth and seventh day. Animals of group B (negative control) were given only vehicle for seven days. Animals of groups C, D and E were respectively administered with 100, 200 and 400 mg/kg body weight of quail egg for the first four days and with vehicle, quail egg and CCl4 for the fifth, sixth and seventh day. Animals were subsequently anaesthetized, and blood samples were taken for the estimation of albumin, alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), total protein (TP) and bilirubin. The liver was isolated for histopathological studies. &lt;strong&gt;Results:&lt;/strong&gt; The levels of ALT, ALP and TP were significantly affected (p &amp;lt; 0.05) in CCl4 fed groups, indicating liver injury. The effects were reduced significantly (p &amp;lt; 0.05) after treatment of rats with quail egg. Furthermore, histopathological studies of the liver tissues also supported the hepatoprotective activity of quail egg- photomicrographs of treated groups showed mild reduction in vacuolarisation/ballooning degeneration of the hepatocytes. &lt;strong&gt;Conclusion:&lt;/strong&gt; Quail egg showed some potentials of protecting the liver from damage by stabilising the levels of ALP, ALT and TP and reducing the degeneration of the hepatocytes. Thus, this finding has provided information that suggests utilising quail egg for treatment of liver dysfunction.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Dandare Shamsudeen Umar&lt;sup&gt;1*,&lt;/sup&gt; Bawa Muhammad&lt;sup&gt;1&lt;/sup&gt;, Wasagu Ibrahim Zubairu&lt;sup&gt;2&lt;/sup&gt; and Magaji Umar Faruk&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;br /&gt;
&lt;sup&gt;1&lt;/sup&gt;Department of Biochemistry, Faculty of Science,&lt;br /&gt;
&lt;sup&gt;2&lt;/sup&gt;Department of Chemical Pathology, Faculty of Medical Laboratory Science,&lt;br /&gt;
Usmanu Danfodiyo University, P.M.B. 2346, Sokoto, Nigeria&lt;/p&gt;
</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Dandare Shamsudeen Umar</style></author><author><style face="normal" font="default" size="100%">Bawa Muhammad</style></author><author><style face="normal" font="default" size="100%">Wasagu Ibrahim Zubairu</style></author><author><style face="normal" font="default" size="100%">Magaji Umar Faruk</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective Effect of Quail Egg Against Carbontetrachloride (CCl4) Induced Hepatic Damage in Albino Rats</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Carbon tetrachloride</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatoprotection</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatotoxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Histopathology.</style></keyword><keyword><style  face="normal" font="default" size="100%">Quail egg</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">27th Dec, 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">7</style></volume><pages><style face="normal" font="default" size="100%">102-106</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; Quail egg has been used traditionally in the treatment of many ailments. Despite the wide speculations of its involvement in the treatment of liver diseases, very little scientific evidence exist to support this claim. This work investigated the hepatoprotective effect of quail egg against carbon tetrachloride (CCl&lt;sub&gt;4&lt;/sub&gt;) induced liver damage in albino rats.&lt;strong&gt; Materials and Methods:&lt;/strong&gt; The rats were divided into five groups of five rats per group. Animals of group A (positive control) were fed with vehicle (distilled water) on the first four days and with vehicle and CCl4 on the fifth, sixth and seventh day. Animals of group B (negative control) were given only vehicle for seven days. Animals of groups C, D and E were respectively administered with 100, 200 and 400 mg/kg body weight of quail egg for the first four days and with vehicle, quail egg and CCl&lt;sub&gt;4&lt;/sub&gt; for the fifth, sixth and seventh day. Animals were subsequently anaesthetized, and blood samples were taken for the estimation of albumin, alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), total protein (TP) and bilirubin. The liver was isolated for histopathological studies. &lt;strong&gt;Results: &lt;/strong&gt;The levels of ALT, ALP and TP were significantly affected (p &amp;lt; 0.05) in CCl&lt;sub&gt;4&lt;/sub&gt; fed groups, indicating liver injury. The effects were reduced significantly (p &amp;lt; 0.05) after treatment of rats with quail egg. Furthermore, histopathological studies of the liver tissues also supported the hepatoprotective activity of quail egg- photomicrographs of treated groups showed mild reduction in vacuolarisation/ballooning degeneration of the hepatocytes. &lt;strong&gt;Conclusion: &lt;/strong&gt;Quail egg showed some potentials of protecting the liver from damage by stabilising the levels of ALP, ALT and TP and reducing the degeneration of the hepatocytes. Thus, this finding has provided information that suggests utilising quail egg for treatment of liver dysfunction.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key Words: &lt;/strong&gt;Quail egg, Carbon tetrachloride, Hepatotoxicity, Hepatoprotection, Histopathology.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">102</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Dandare Shamsudeen Umar&lt;sup&gt;1*&lt;/sup&gt;, Bawa Muhammad&lt;sup&gt;1&lt;/sup&gt;, Wasagu Ibrahim Zubairu&lt;sup&gt;2&lt;/sup&gt; and Magaji Umar Faruk&lt;sup&gt;1 &lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Biochemistry, Faculty of Science,&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Chemical Pathology, Faculty of Medical Laboratory Science, Usmanu Danfodiyo University, P.M.B. 2346, Sokoto, Nigeria.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Noor Kamil</style></author><author><style face="normal" font="default" size="100%">Hafi z Syed Imran-ul-Haque</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hepatoprotective Effect of Calotropis procera in Isoniazid and Rifampicin Induced Hepatotoxicity</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Calotropis procera</style></keyword><keyword><style  face="normal" font="default" size="100%">Hepatoprotective</style></keyword><keyword><style  face="normal" font="default" size="100%">isoniazid</style></keyword><keyword><style  face="normal" font="default" size="100%">rifampicin</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2nd July 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">9-14</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align:justify&quot;&gt;&lt;strong&gt;Objective:&lt;/strong&gt; In this study anti-tubercular drugs (isoniazid and rifampicin) induced liver toxicity has been studied for the hepatoprotective effect of hydroethanolic extract of &lt;em&gt;Calotropis procera&lt;/em&gt; (CP) flowers in rats. &lt;strong&gt;Materials and Method:&lt;/strong&gt; Animals were divided into four groups, group Awas given normal saline (1ml/kg), group B received Isoniazid (INH) (50mg/kg) and Rifampicin (RMP)(100mg/kg) group C received INH (50mg/kg), RMP(100mg/kg) and CP(150mg/kg)orally for fourteen days. &lt;strong&gt;Results:&lt;/strong&gt; Biochemical markers of liver toxicity such as AST,ALT,ALP, bilirubin and tissue histology were done inall groups. Anti-Tubercular (Anti-TB) drugs (INH 50mg/kg and RMP100mg/kg) have enhanced the ALT, AST, ALP, bilirubin and histological changes in liver, whereas co-administration of anti-TB drugs with Calotropis procera has reduced these levels within the normal range. &lt;strong&gt;Conclusion:&lt;/strong&gt; Findings of this study showed the hepatoprotective effct of Calotropis Proceraagainst Isoniazid and Rifampicinadministration to reduce the liver damage for chronic treatment.&lt;/p&gt;&lt;p style=&quot;text-align:justify&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt; Isoniazid, Rifampicin, &lt;em&gt;Calotropis procera&lt;/em&gt;, Hepatoprotective.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Noor Kamil&lt;sup&gt;1&lt;/sup&gt;, Hafiz Syed Imran-ul-Haque&lt;/strong&gt;&lt;sup&gt;&lt;strong&gt;2 &lt;/strong&gt;&lt;/sup&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982-KSA,&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacology, Dow International Medical College, Dow University of Health Sciences, Karachi-Pakistan.&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rajani Srivastava</style></author><author><style face="normal" font="default" size="100%">Alok Mukerjee</style></author><author><style face="normal" font="default" size="100%">Amita Verma</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">High-Performance Thin-Layer Chromatography Fingerprinting of Ethnopharmacological Important Seeds of Wrightia tinctoria</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alcoholic extract</style></keyword><keyword><style  face="normal" font="default" size="100%">chloroform extract</style></keyword><keyword><style  face="normal" font="default" size="100%">High-performance thin-layer chromatography fingerprinting</style></keyword><keyword><style  face="normal" font="default" size="100%">petether extract</style></keyword><keyword><style  face="normal" font="default" size="100%">Wrightia tinctoria</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">3rd Sept, 2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">10-14</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt;&lt;em&gt;Wrightia tinctoria&lt;/em&gt; R. Br. belongs to family &lt;em&gt;Apocynaceae&lt;/em&gt; commonly called as sweet Indrajao, Pala indigo plant, Dyer&amp;rsquo;s Oleander. &amp;ldquo;Jaundice curative tree&amp;rdquo; in south India. &lt;strong&gt;Materials and Methods:&lt;/strong&gt; A method has been developed for different extracts of &lt;em&gt;W. tinctoria&lt;/em&gt; for high-performance thin-layer chromatography (HPTLC) fingerprinting analysis for identification and quantification of the marker compound.&lt;strong&gt; Result:&lt;/strong&gt; The satisfactory resolution was obtained in the solvent system toluene:ethyl acetate v/v (8:2) for petroleum ether extract, toluene:ethyl acetate v/v (7:3) for chloroform extract and toluene:ethyl acetate:formic acid v/v (7:3:0.1) for alcoholic extract. &lt;strong&gt;Conclusion:&lt;/strong&gt; The HPTLC fingerprinting profile developed for different extracts of &lt;em&gt;W. tinctoria&lt;/em&gt; will help in proper identification and quantification of the marker compound.&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Key words:&lt;/strong&gt; High-performance thin-layer chromatography fingerprinting, &lt;em&gt;Wrightia tinctoria&lt;/em&gt;, petether extract, chloroform extract, alcoholic extract.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">6</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">10</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Rajani Srivastava&lt;sup&gt;1*&lt;/sup&gt;, Alok Mukerjee&lt;sup&gt;2&lt;/sup&gt;, Amita Verma&lt;sup&gt;1&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmaceutical Sciences, Faculty of Health Sciences, Sam Higginbottom Institute of Agriculture, Technology and Sciences-Deemed University, Allahabad, Uttar Pradesh, India,&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;United Institute of Pharmacy, Allahabad, Uttar Pradesh, India&lt;/p&gt;</style></auth-address></record><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Azadeh Hamedi,</style></author><author><style face="normal" font="default" size="100%">Abdolali Mohagheghzadeh</style></author><author><style face="normal" font="default" size="100%">Samaneh Rivaz</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Hydrodistilled volatile constituents obtained from the roots of Operculina turpethum</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Operculina turpethum</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">18th Feb,2014</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">6</style></volume><pages><style face="normal" font="default" size="100%">115-116</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;em&gt;Operculina turpethum&lt;/em&gt; (basionym: &lt;em&gt;Convolvulus turpethum&lt;/em&gt; L.; homotypic synonym:&lt;em&gt;Ipomoea turpethum&lt;/em&gt; L., &lt;em&gt;Merremia turpethum&lt;/em&gt; L.) is a perennial climber from Convolvulaceae. The plant roots, which are called Turbad in Persian folk medicine, are a strong purgative and have also been used for phlegmatic disorders, burns, fevers, jaundice, cough, uterine problems, joints and muscles pain, paralysis and sciatica.&lt;sup&gt;[1]&lt;/sup&gt; The plant has a wide range of applications in Ayurvedic formulations. Extracts of Turbad exhibited antioxidant, antihyperglycemic, antiulcer, anti-inflammatory, antimicrobial, cytotoxic, immunodulatory and antiedema activities.&lt;sup&gt;[2]&lt;/sup&gt; read more..,&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">115</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Azadeh Hamedi&lt;sup&gt;*,a&lt;/sup&gt;, Abdolali Mohagheghzadeh&lt;sup&gt;b&lt;/sup&gt; and Samaneh Rivaz&lt;sup&gt;c&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;a&lt;/sup&gt;Medicinal Plants Processing Research Center, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran,&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;b&lt;/sup&gt;Department of Traditional Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran&lt;/p&gt;&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;c&lt;/sup&gt;Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.&lt;/p&gt;</style></auth-address></record></records></xml>